المؤلفون: Emma V. Jones, Joon Rhee, Jérôme Alexandre, Zhongwu Lai, L Opincar, Matthew G Krebs, Yeon Hee Park, Jean Pierre Delord, Antoine Italiano, Anna M. L. Coenen-Stass, Seock-Ah Im, Sara Bastian, Sophie Postel-Vinay, Sakshi Gulati, Susan M. Domchek, Ding Wang, Saiama N. Waqar, Haiyan Gao, Benoit You, P. Herbolsheimer, M. Lanasa, Helen K. Angell, Iwanka Kozarewa, Vidalba Rocher-Ros, Bella Kaufman

المصدر: Domchek, S M, Postel-Vinay, S, Im, S-A, Park, Y H, Delord, J-P, Italiano, A, Alexandre, J, You, B, Bastian, S, Krebs, M G, Wang, D, Waqar, S N, Lanasa, M, Rhee, J, Gao, H, Rocher-Ros, V, Jones, E V, Gulati, S, Coenen-Stass, A, Kozarewa, I, Lai, Z, Angell, H K, Opincar, L, Herbolsheimer, P & Kaufman, B 2020, ' Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA) : an open-label, multicentre, phase 1/2, basket study ', The Lancet. Oncology, vol. 21, no. 9, pp. 1155-1164 . https://doi.org/10.1016/S1470-2045Test(20)30324-7

مصطلحات موضوعية: 0301 basic medicine, Oncology, Durvalumab, Germ-Line Mutation/genetics, B7-H1 Antigen, Piperazines, chemistry.chemical_compound, 0302 clinical medicine, Medicine, Neoplasm Metastasis, Phthalazines/administration & dosage, Manchester Cancer Research Centre, BRCA1 Protein, Antibodies, Monoclonal, Middle Aged, BRCA2 Protein/genetics, Metastatic breast cancer, Neoplasm Recurrence, Local/drug therapy, Tolerability, 030220 oncology & carcinogenesis, Female, Adult, medicine.medical_specialty, Adolescent, B7-H1 Antigen/antagonists & inhibitors, Breast Neoplasms, Antibodies, Monoclonal/administration & dosage, Olaparib, Young Adult, 03 medical and health sciences, Breast cancer, Breast Neoplasms/drug therapy, Internal medicine, Humans, Lung cancer, Adverse effect, Germ-Line Mutation, Aged, BRCA2 Protein, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, Piperazines/administration & dosage, medicine.disease, Clinical trial, 030104 developmental biology, chemistry, BRCA1 Protein/genetics, Phthalazines, Neoplasm Recurrence, Local, business

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c34416fb3adf2a299c05113cf960a2cTest
https://doi.org/10.1016/s1470-2045Test(20)30324-7

المؤلفون: Carsten Müller-Tidow, Kaya Veelken, Stefan Schönland, Ute Hegenbart, Alexander Carpinteiro, Christoph Kimmich, Axel Benner, Tobias Dittrich, Jörg Beimler, Dirk Hose, Timon Hansen, Tobias Terzer, Anna Jauch, Hartmut Goldschmidt, Anja Seckinger, Stefan Wörner

المساهمون: Hematology, Basic (bio-) Medical Sciences

المصدر: Blood. 135:1517-1530

مصطلحات موضوعية: Male, medicine.medical_specialty, Albuminuria/diagnosis, Immunology, Medizin, Plasma cell dyscrasia, Salvage therapy, Kidney Function Tests, Antibodies, Monoclonal/administration & dosage, Biochemistry, Gastroenterology, Immunoglobulin Light Chains/blood, Internal medicine, medicine, AL amyloidosis, Humans, business.industry, Proportional hazards model, Hazard ratio, biomarkers, Daratumumab, Cell Biology, Hematology, Prognosis, medicine.disease, Survival Analysis, Treatment Outcome, Immunoglobulin G/blood, Immunoglobulin Light-chain Amyloidosis/complications, oncology, Albuminuria, Female, Neoplasm Grading, Lymphocytopenia, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf74ef2016e119f5d5ffa6dd43f5f99Test
https://doi.org/10.1182/blood.2019003633Test

المؤلفون: Davide Rossi, Rahel Schwotzer, Raphael Heimgartner, Andreas J. Flammer, Georg Stussi, Bernhard Gerber, Guido Ghilardi, Erika Lerch, Christine Waibel, Harald Seeger, Clemens Caspar, Stefanie Pederiva, Thomas Fehr, Elena Bianchi, Markus G. Manz, Sofie Brouwers

المساهمون: Pharmaceutical and Pharmacological Sciences, Clinical Pharmacology and Clinical Pharmacy, Experimental Pharmacology, University of Zurich, Schwotzer, Rahel

المصدر: Hematological Oncology. 37:595-600

مصطلحات موضوعية: Male, Cancer Research, 2720 Hematology, Immunoglobulin Light-chain Amyloidosis/diagnosis, Severity of Illness Index, Gastroenterology, Antineoplastic Agents, Immunological, 0302 clinical medicine, Bone Marrow, Recurrence, Immunoglobulin Light-chain Amyloidosis, 10035 Clinic for Nephrology, 1306 Cancer Research, Bortezomib, Amyloidosis, Antibodies, Monoclonal, Hematology, General Medicine, Middle Aged, Treatment Outcome, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Retreatment, 10209 Clinic for Cardiology, 2730 Oncology, Female, medicine.drug, Adult, medicine.medical_specialty, Plasma Cells, Infections/etiology, 610 Medicine & health, Infections, Antibodies, Monoclonal/administration & dosage, 03 medical and health sciences, Antineoplastic Agents, Immunological/administration & dosage, Refractory, Internal medicine, medicine, AL amyloidosis, Humans, Lymphocyte Count, Adverse effect, Aged, Lenalidomide, Bone Marrow/metabolism, business.industry, Daratumumab, medicine.disease, Drug Resistance, Neoplasm, 10032 Clinic for Oncology and Hematology, Plasma Cells/pathology, Bone marrow, business, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afce2e4f761edbd1d13b6d39b85360dfTest
https://doi.org/10.1002/hon.2677Test

المؤلفون: Kastritis E., Palladini G., Minnema M. C., Wechalekar A. D., Jaccard A., Lee H. C., Sanchorawala V., Gibbs S., Mollee P., Venner C. P., Lu J., Schonland S., Gatt M. E., Suzuki K., Kim K., Cibeira M. T., Beksac M., Libby E., Valent J., Hungria V., Wong S. W., Rosenzweig M., Bumma N., Huart A., Dimopoulos M. A., Bhutani D., Waxman A. J., Goodman S. A., Zonder J. A., Lam S., Song K., Hansen T., Manier S., Roeloffzen W., Jamroziak K., Kwok F., Shimazaki C., Kim J. -S., Crusoe E., Ahmadi T., Tran N., Qin X., Vasey S. Y., Tromp B., Schecter J. M., Weiss B. M., Zhuang S. H., Vermeulen J., Merlini G., Comenzo R. L., Bradley Augustson, Fiona Kwok, Peter Mollee, Simon Gibbs, Chantal Doyen, Greet Bries, Isabelle Vande Broek, Ka Lung Wu, Koen Theunissen, Koen Van Eygen, Michel Delforge, Nathalie Meuleman, Philip Vlummens, Angelo Maiolino, Breno Moreno de Gusmão, Carlos Eduardo Miguel, Edvan Crusoe, Fernanda Moura, Fernanda Seguro, Jandey Bigonha, Juliane Musacchio, Karla Zanella, Laura Garcia, Marcelo Eduardo Zanella Capra, Reijane Alves de Assis, Rosane Bittencourt, Vania Hungria, Walter Braga, Wolney Barreto, Christopher Venner, Donna Reece, Emilie Lemieux-Blanchard, Kevin Song, Michael Sebag, Selay Lam, Victor Zepeda, Haitao Zhang, Jianda Hu, Jin Lu, Juan Li, Songfu Jiang, Ting Niu, Wenming Chen, Xiaonong Chen, Zhen Cai, Zhou Fude, Maja Oelholm Vase, Morten Salomo, Niels Abildgaard, Alain Fuzibet, Anne-Marie Stoppa, Arnaud Jaccard, Bertrand Arnulf, Bruno Moulin, Bruno Royer, David Ghez, Denis Caillot, Dominique Chauveau, Franck Bridoux, Lauriane Clement-Filliatre, Lionel Karlin, Lotfi Benboubker, Mamoun Dib, Margaret Macro, Mohamad Mohty, Olivier Decaux, Olivier Hermine, Olivier Tournilhac, Philippe Moreau, Salomon Manier, Sylvain Choquet, Véronique Dorvaux, Alexander Carpinteiro, Axel Nogai, Britta Besemer, Christoph Roellig, Roland Fenk, Stefan Knop, Stefan Schönland, Timon Hansen, Argiris Symeonidis, Efstathios Kastritis, Gabor Mikala, Tamás Masszi, Zsolt Nagy, Celia Suriu, Hila Magen, Iuliana Vaxman, Lev Shvidel, Meir Preis, Moshe Gatt, Noa Lavi, Osnat Jarchowsky, Tamar Tadmor, Yael Cohen, Angelo Vacca, Giovanni Palladini, Mario Boccadoro, Maurizio Martelli, Maurizio Musso, Michele Cavo, Chihiro Shimazaki, Hiroyuki Takamatsu, Kazutaka Sunami, Kenshi Suzuki, Nagaaki Katoh, Shinsuke Iida, Takayuki Ikezoe, Tomoaki Fujisaki, Yuta Katayama, Chang Ki Min, Ho-Jin Shin, Jin Seok Kim, Jung Yong Hong, Ki Hyun Kim, Sung-Soo Yoon, Aline Ramirez, Alvaro Cabrera, Christian Ramos, David Gomez Almaguer, Deborah Martinez, Guillermo Ruiz, Helen Dayani Caballero, Juan Antonio Flores Jimenez, Annemiek Broijl, Laurens Nieuwenhuizen, Monique Minnema, Paula Ypma, Wilfried Roeloffzen, Dominik Dytfeld, Grzegorz Charlinski, Grzegorz Helbig, Krzysztof Jamroziak, Sebastian Grosicki, Wieslaw Jedrzejczak, Albert Oriol Rocafiguera, Elham Askari, Fernando Escalante Barrigon, Isabel Krsnik Castello, Javier De la Rubia Comos, Jesus Martin Sanchez, Joaquin Martinez Lopez, Jose Angel Hernandez Rivas, Luis Felipe Casado Montero, Maria Jesus Blanchard Rodriguez, Maria Teresa Cibeira Lopez, Maria Victoria Mateos Manteca, Marta Sonia Gonzalez Perez, Mercedes Gironella Mesa, Rafael Rios Tamayo, Ramon Lecumberri Villamediana, Ricarda Garcia Sanchez, Sunil Lakhwani, Yolanda Gonzalez, Hareth Nahi, Kristina Carlsson, Markus Hansson, Ulf-Henrik Mellqvist, Ali Unal, Burhan Ferhanoglu, Hayri Ozsan, Levent Undar, Mehmet Turgut, Mehmet Yilmaz, Meral Beksac, Muhlis Cem Ar, Muzaffer Demir, Sevgi Besisik, Ashutosh Wechalekar, Jamie Cavenagh, Jim Cavet, Mark Cook, Rachel Hall, Adam Waxman, Anuj Mahindra, Cesar Rodriguez Valdes, Christine Ye, Craig Reeder, Daphne Friedman, David Siegel, Divaya Bhutani, Edward Libby, Eva Medvedova, Frank Passero, Giada Bianchi, Giampaolo Talamo, Guido Tricot, Hans Lee, Heather Landau, Jan Moreb, Jason Valent, Jeffrey Matous, Jeffrey A Zonder, Jesus Berdeja, Jonathan Kaufman, Keith Stockerl-Goldstein, Keren Osman, Ketan Doshi, Kevin Barton, Larry Anderson, Manisha Bhutani, Mehmet Kocoglu, Michael Rosenzweig, Michael Schuster, Michaela Liedtke, Morie Gertz, Naresh Bumma, Natalie Callander, Raymond Comenzo, Robert Vescio, Roger Pearse, Sandy W Wong, Stacey A Goodman, Stefano Tarantolo, Taimur Sher, Tibor Kovacsovics, Tomer Mark, Vaishali Sanchorawala, William Bensinger

المساهمون: Role of intra-Clonal Heterogeneity and Leukemic environment in ThErapy Resistance of chronic leukemias (CHELTER), Université Clermont Auvergne (UCA), Kastritis E., Palladini G., Minnema M.C., Wechalekar A.D., Jaccard A., Lee H.C., Sanchorawala V., Gibbs S., Mollee P., Venner C.P., Lu J., Schonland S., Gatt M.E., Suzuki K., Kim K., Cibeira M.T., Beksac M., Libby E., Valent J., Hungria V., Wong S.W., Rosenzweig M., Bumma N., Huart A., Dimopoulos M.A., Bhutani D., Waxman A.J., Goodman S.A., Zonder J.A., Lam S., Song K., Hansen T., Manier S., Roeloffzen W., Jamroziak K., Kwok F., Shimazaki C., Kim J.-S., Crusoe E., Ahmadi T., Tran N., Qin X., Vasey S.Y., Tromp B., Schecter J.M., Weiss B.M., Zhuang S.H., Vermeulen J., Merlini G., Comenzo R.L., Bradley Augustson, Fiona Kwok, Peter Mollee, Simon Gibbs, Chantal Doyen, Greet Bries, Isabelle Vande Broek, Ka Lung Wu, Koen Theunissen, Koen Van Eygen, Michel Delforge, Nathalie Meuleman, Philip Vlummens, Angelo Maiolino, Breno Moreno de Gusmão, Carlos Eduardo Miguel, Edvan Crusoe, Fernanda Moura, Fernanda Seguro, Jandey Bigonha, Juliane Musacchio, Karla Zanella, Laura Garcia, Marcelo Eduardo Zanella Capra, Reijane Alves de Assis, Rosane Bittencourt, Vania Hungria, Walter Braga, Wolney Barreto, Christopher Venner, Donna Reece, Emilie Lemieux-Blanchard, Kevin Song, Michael Sebag, Selay Lam, Victor Zepeda, Haitao Zhang, Jianda Hu, Jin Lu, Juan Li, Songfu Jiang, Ting Niu, Wenming Chen, Xiaonong Chen, Zhen Cai, Zhou Fude, Maja Oelholm Vase, Morten Salomo, Niels Abildgaard, Alain Fuzibet, Anne-Marie Stoppa, Arnaud Jaccard, Bertrand Arnulf, Bruno Moulin, Bruno Royer, David Ghez, Denis Caillot, Dominique Chauveau, Franck Bridoux, Lauriane Clement-Filliatre, Lionel Karlin, Lotfi Benboubker, Mamoun Dib, Margaret Macro, Mohamad Mohty, Olivier Decaux, Olivier Hermine, Olivier Tournilhac, Philippe Moreau, Salomon Manier, Sylvain Choquet, Véronique Dorvaux, Alexander Carpinteiro, Axel Nogai, Britta Besemer, Christoph Roellig, Roland Fenk, Stefan Knop, Stefan Schönland, Timon Hansen, Argiris Symeonidis, Efstathios Kastritis, Gabor Mikala, Tamás Masszi, Zsolt Nagy, Celia Suriu, Hila Magen, Iuliana Vaxman, Lev Shvidel, Meir Preis, Moshe Gatt, Noa Lavi, Osnat Jarchowsky, Tamar Tadmor, Yael Cohen, Angelo Vacca, Giovanni Palladini, Mario Boccadoro, Maurizio Martelli, Maurizio Musso, Michele Cavo, Chihiro Shimazaki, Hiroyuki Takamatsu, Kazutaka Sunami, Kenshi Suzuki, Nagaaki Katoh, Shinsuke Iida, Takayuki Ikezoe, Tomoaki Fujisaki, Yuta Katayama, Chang Ki Min, Ho-Jin Shin, Jin Seok Kim, Jung Yong Hong, Ki Hyun Kim, Sung-Soo Yoon, Aline Ramirez, Alvaro Cabrera, Christian Ramos, David Gomez Almaguer, Deborah Martinez, Guillermo Ruiz, Helen Dayani Caballero, Juan Antonio Flores Jimenez, Annemiek Broijl, Laurens Nieuwenhuizen, Monique Minnema, Paula Ypma, Wilfried Roeloffzen, Dominik Dytfeld, Grzegorz Charlinski, Grzegorz Helbig, Krzysztof Jamroziak, Sebastian Grosicki, Wieslaw Jedrzejczak, Albert Oriol Rocafiguera, Elham Askari, Fernando Escalante Barrigon, Isabel Krsnik Castello, Javier De la Rubia Comos, Jesus Martin Sanchez, Joaquin Martinez Lopez, Jose Angel Hernandez Rivas, Luis Felipe Casado Montero, Maria Jesus Blanchard Rodriguez, Maria Teresa Cibeira Lopez, Maria Victoria Mateos Manteca, Marta Sonia Gonzalez Perez, Mercedes Gironella Mesa, Rafael Rios Tamayo, Ramon Lecumberri Villamediana, Ricarda Garcia Sanchez, Sunil Lakhwani, Yolanda Gonzalez, Hareth Nahi, Kristina Carlsson, Markus Hansson, Ulf-Henrik Mellqvist, Ali Unal, Burhan Ferhanoglu, Hayri Ozsan, Levent Undar, Mehmet Turgut, Mehmet Yilmaz, Meral Beksac, Muhlis Cem Ar, Muzaffer Demir, Sevgi Besisik, Ashutosh Wechalekar, Jamie Cavenagh, Jim Cavet, Mark Cook, Rachel Hall, Adam Waxman, Anuj Mahindra, Cesar Rodriguez Valdes, Christine Ye, Craig Reeder, Daphne Friedman, David Siegel, Divaya Bhutani, Edward Libby, Eva Medvedova, Frank Passero, Giada Bianchi, Giampaolo Talamo, Guido Tricot, Hans Lee, Heather Landau, Jan Moreb, Jason Valent, Jeffrey Matous, Jeffrey A Zonder, Jesus Berdeja, Jonathan Kaufman, Keith Stockerl-Goldstein, Keren Osman, Ketan Doshi, Kevin Barton, Larry Anderson, Manisha Bhutani, Mehmet Kocoglu, Michael Rosenzweig, Michael Schuster, Michaela Liedtke, Morie Gertz, Naresh Bumma, Natalie Callander, Raymond Comenzo, Robert Vescio, Roger Pearse, Sandy W Wong, Stacey A Goodman, Stefano Tarantolo, Taimur Sher, Tibor Kovacsovics, Tomer Mark, Vaishali Sanchorawala, William Bensinger

المصدر: New England Journal of Medicine, 385(1), 46-58. MASSACHUSETTS MEDICAL SOC
New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2021, 385 (1), pp.46-58. ⟨10.1056/NEJMoa2028631⟩
Kastritis, E, Palladini, G, Minnema, M C, Wechalekar, A D, Jaccard, A, Lee, H C, Sanchorawala, V, Gibbs, S, Mollee, P, Venner, C P, Lu, J, Schönland, S, Gatt, M E, Suzuki, K, Kim, K, Cibeira, M T, Beksac, M, Libby, E, Valent, J, Hungria, V, Wong, S W, Rosenzweig, M, Bumma, N, Huart, A, Dimopoulos, M A, Bhutani, D, Waxman, A J, Goodman, S A, Zonder, J A, Lam, S, Song, K, Hansen, T, Manier, S, Roeloffzen, W, Jamroziak, K, Kwok, F, Shimazaki, C, Kim, J-S, Crusoe, E, Ahmadi, T, Tran, N, Qin, X, Vasey, S Y, Tromp, B, Schecter, J M, Weiss, B M, Zhuang, S H, Vermeulen, J, Merlini, G, for the ANDROMEDA Trial Investigators & Abildgaard, N 2021, ' Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis ', The New England Journal of Medicine, vol. 385, no. 1, pp. 46-58 . https://doi.org/10.1056/NEJMoa2028631Test

مصطلحات موضوعية: Male, Treatment outcome, Immunoglobulin Light-chain Amyloidosis/drug therapy, CD38, Dexamethasone, Cyclophosphamide/administration & dosage, Bortezomib, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Medicine, CRITERIA, Immunoglobulin Light-chain Amyloidosis, ComputingMilieux_MISCELLANEOUS, Aged, 80 and over, biology, Amyloidosis, Antibodies, Monoclonal, [SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/Hematology, General Medicine, Middle Aged, 3. Good health, Treatment Outcome, 030220 oncology & carcinogenesis, Female, Antibody, Human, Adult, Dexamethasone/administration & dosage, ANTIBODY DARATUMUMAB, Immunoglobulin light chain, DIAGNOSIS, Antibodies, Monoclonal/administration & dosage, Disease-Free Survival, 03 medical and health sciences, Humans, Cyclophosphamide, Aged, Antineoplastic Combined Chemotherapy Protocol, business.industry, Antineoplastic Combined Chemotherapy Protocols/adverse effects, AL AMYLOIDOSIS, Daratumumab, Amyloid fibril, medicine.disease, Molecular biology, Immunoglobulin Light-chain Amyloidosi, biology.protein, Bortezomib/administration & dosage, business, 030215 immunology

وصف الملف: application/pdf; application/octet-stream; STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b685c6c0877c79c6650b72aaec2ee26Test
https://research.rug.nl/en/publications/74938df3-de87-47e6-b870-977d2f5bae19Test

المؤلفون: E. Laffitte, E. Brocco

المصدر: Clinical and experimental dermatology, Vol. 46, No 7 (2021) pp. 1322-1324

مصطلحات موضوعية: Adult, medicine.medical_specialty, Pityriasis Rubra Pilaris / drug therapy, Injections, Subcutaneous, Antibodies, Monoclonal / administration & dosage, Dermatology, Antibodies, Monoclonal / therapeutic use, Latent Tuberculosis, medicine, Humans, Pityriasis Rubra Pilaris / complications, Antibiotics, Antitubercular, ddc:616, Risankizumab, business.industry, Antibodies, Monoclonal, Antibiotics, Antitubercular / therapeutic use, medicine.disease, Pityriasis Rubra Pilaris / pathology, Pityriasis Rubra Pilaris, Pityriasis rubra pilaris, Female, Rifampin / therapeutic use, Rifampin, business, Latent Tuberculosis / complications, Latent Tuberculosis / drug therapy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179321a2a1d09232c2180a8677bda8e1Test
https://pubmed.ncbi.nlm.nih.gov/33914925Test

المؤلفون: Joseph R. Mace, Mourad Tiab, Philippe Moreau, Torben Plesner, Margaret Macro, Aurore Perrot, Katja Weisel, Noopur Raje, Michael O'Dwyer, Maia Trial Investigators, Shaji Kumar, Tahamtan Ahmadi, Clarissa M. Uhlar, Michel Attal, Ming Qi, Hang Quach, Thierry Facon, Hartmut Goldschmidt, Cyrille Hulin, Jianping Wang, Laurent Frenzel, Hareth Nahi, Robert Z. Orlowski, Rachel Kobos, Nizar J. Bahlis, Christopher P. Venner, Rian Van Rampelbergh, Christopher Chiu, Xavier Leleu, Supratik Basu, Saad Z. Usmani

المصدر: Facon, T, Kumar, S, Plesner, T, Orlowski, R Z, Moreau, P, Bahlis, N, Basu, S, Nahi, H, Hulin, C, Quach, H, Goldschmidt, H, O’Dwyer, M, Perrot, A, Venner, C P, Weisel, K, Mace, J R, Raje, N, Attal, M, Tiab, M, Macro, M, Frenzel, L, Leleu, X, Ahmadi, T, Chiu, C, Wang, J, Rampelbergh, R V, Uhlar, C M, Kobos, R, Qi, M, Usmani, S Z, MAIA Trial Investigators & Abildgaard, N 2019, ' Daratumumab plus lenalidomide and dexamethasone for untreated Myeloma ', New England Journal of Medicine, vol. 380, no. 22, pp. 2104-2115 . https://doi.org/10.1056/NEJMoa1817249Test

مصطلحات موضوعية: Dexamethasone/administration & dosage, Male, Oncology, medicine.medical_specialty, Neutropenia, Multiple Myeloma/drug therapy, 030204 cardiovascular system & hematology, Antibodies, Monoclonal/administration & dosage, Antibodies, Dexamethasone, 03 medical and health sciences, 0302 clinical medicine, Neutropenia/chemically induced, Internal medicine, Monoclonal, Antineoplastic Combined Chemotherapy Protocols, 80 and over, medicine, Lenalidomide/administration & dosage, Humans, 030212 general & internal medicine, Lenalidomide, Multiple myeloma, Aged, Aged, 80 and over, Isatuximab, Bortezomib, business.industry, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Standard treatment, Antibodies, Monoclonal, Female, Middle Aged, Multiple Myeloma, Progression-Free Survival, Daratumumab, General Medicine, medicine.disease, Transplantation, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ab3633dfb860f2b0cd95f9e39f460dTest
https://doi.org/10.1056/nejmoa1817249Test

المؤلفون: Mateos, María-Victoria, Dimopoulos, Meletios A, Cavo, Michele, Suzuki, Kenshi, Jakubowiak, Andrzej, Knop, Stefan, Doyen, Chantal, Lucio, Paulo, Nagy, Zsolt, Kaplan, Polina, Pour, Ludek, Cook, Mark, Grosicki, Sebastian, Crepaldi, Andre, Liberati, Anna M, Campbell, Philip, Shelekhova, Tatiana, Yoon, Sung-Soo, Iosava, Genadi, Fujisaki, Tomoaki, Garg, Mamta, Chiu, Christopher, Wang, Jianping, Carson, Robin, Crist, Wendy, Deraedt, William, Nguyen, Huong, Qi, Ming, San-Miguel, Jesus, ALCYONE Trial Investigators

المساهمون: UCL - (MGD) Service d'hématologie, UCL - SSS/IREC/MONT - Pôle Mont Godinne, Clinical sciences, Hematology, Mateos, María-Victoria, Dimopoulos, Meletios A, Cavo, Michele, Suzuki, Kenshi, Jakubowiak, Andrzej, Knop, Stefan, Doyen, Chantal, Lucio, Paulo, Nagy, Zsolt, Kaplan, Polina, Pour, Ludek, Cook, Mark, Grosicki, Sebastian, Crepaldi, Andre, Liberati, Anna M, Campbell, Philip, Shelekhova, Tatiana, Yoon, Sung-Soo, Iosava, Genadi, Fujisaki, Tomoaki, Garg, Mamta, Chiu, Christopher, Wang, Jianping, Carson, Robin, Crist, Wendy, Deraedt, William, Nguyen, Huong, Ming, Qi, San-Miguel, Jesus for the ALCYONE Trial Investigators

المصدر: New England Journal of Medicine, Vol. 378, no. 6, p. 518-528 (2018)

مصطلحات موضوعية: Male, Oncology, Melphalan, Kaplan-Meier Estimate, Bortezomib, Prednisone/administration & dosage, 0302 clinical medicine, Prednisone, bortezomib, melphalan, prednisone, hemic and lymphatic diseases, Monoclonal, Antineoplastic Combined Chemotherapy Protocols, Multiple myeloma, Medicine (all), Standard treatment, antineoplastic agentbortezomibdaratumumabmelphalanmonoclonal antibodyprednisone, Antibodies, Monoclonal, General Medicine, Middle Aged, Intention to Treat Analysis, 3. Good health, Survival Rate, 030220 oncology & carcinogenesis, oncology, Female, Infection, Multiple Myeloma, medicine.drug, Adult, Melphalan/administration & dosage, medicine.medical_specialty, Multiple Myeloma/drug therapy, Infections, Antibodies, Monoclonal/administration & dosage, Antibodies, Disease-Free Survival, 03 medical and health sciences, Internal medicine, medicine, Humans, Survival rate, Aged, business.industry, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Daratumumab, Infections/chemically induced, medicine.disease, Follow-Up Studies, Transplantation, Bortezomib/administration & dosage, business, 030215 immunology

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad05469cd382ea0c0c730507710cf6cTest
https://doi.org/10.1056/nejmoa1714678Test

المؤلفون: Torben Plesner, René J. P. Musters, Berris van Kessel, Jeroen F. van Velzen, A. Kate Sasser, Pino J. Poddighe, Marloes E.C. Broekmans, Tuna Mutis, Inger S. Nijhof, Henk M. Lokhorst, Jakub Krejcik, Richard W.J. Groen, Kris A. Frerichs, Sonja Zweegman, Niels W.C.J. van de Donk, Andries C. Bloem, Johan van Meerloo, Christopher Chiu

المساهمون: Hematology laboratory, Hematology, CCA - Cancer biology and immunology, AII - Cancer immunology, Physiology, Human genetics, ACS - Microcirculation, ACS - Atherosclerosis & ischemic syndromes

المصدر: Krejcik, J, Frerichs, K A, Nijhof, I S, van Kessel, B, van Velzen, J, Bloem, A C, Broekmans, M, Zweegman, S, van Meerloo, J, Musters, R J, Poddighe, P, Groen, R, Chiu, C, Plesner, T, Lokhorst, H M, Sasser, A K, Mutis, T & van de Donk, N W C J 2017, ' Monocytes and granulocytes reduce CD38 expression levels on myeloma cells in patients treated with daratumumab ', Clinical Cancer Research, vol. 23, no. 24, pp. 7498-7511 . https://doi.org/10.1158/1078-0432.CCR-17-2027Test
Krejcik, J, Frerichs, K A, Nijhof, I S, van Kessel, B, van Velzen, J F, Bloem, A C, Broekmans, M E C, Zweegman, S, van Meerloo, J, Musters, R J P, Poddighe, P J, Groen, R W J, Chiu, C, Plesner, T, Lokhorst, H M, Sasser, A K, Mutis, T & van de Donk, N W C J 2017, ' Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab ', Clinical Cancer Research, vol. 23, no. 24, pp. 7498-7511 . https://doi.org/10.1158/1078-0432.CCR-17-2027Test
Clinical Cancer Research, 23(24), 7498-7511. American Association for Cancer Research Inc.

مصطلحات موضوعية: Male, Cancer Research, T-Lymphocytes, CD38, Dexamethasone, Monocytes, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, Lenalidomide, Multiple myeloma, Isatuximab, B-Lymphocytes, biology, Antibodies, Monoclonal, B-Lymphocytes/immunology, Middle Aged, Thalidomide, Gene Expression Regulation, Neoplastic, Killer Cells, Natural, Oncology, 030220 oncology & carcinogenesis, Killer Cells, Natural/immunology, ADP-ribosyl Cyclase 1/genetics, Female, Antibody, Multiple Myeloma, Granulocytes/drug effects, Dexamethasone/administration & dosage, Trogocytosis, Multiple Myeloma/drug therapy, Antibodies, Monoclonal/administration & dosage, Article, 03 medical and health sciences, Immune system, Monocytes/drug effects, Cell Line, Tumor, medicine, Humans, Aged, Thalidomide/administration & dosage, Daratumumab, medicine.disease, ADP-ribosyl Cyclase 1, Cell culture, Gene Expression Regulation, Neoplastic/drug effects, Immunology, biology.protein, 030215 immunology, Granulocytes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a411b4972ab21d4db661d3cca064dd68Test
https://doi.org/10.1158/1078-0432.ccr-17-2027Test

المؤلفون: Nushmia Z. Khokhar, Hareth Nahi, Neil Rabin, Donna E. Reece, Nizar J. Bahlis, Meletios A. Dimopoulos, Philippe Moreau, Jesús F. San-Miguel, Hartmut Goldschmidt, Albert Oriol, Dina Ben Yehuda, Saad Z. Usmani, Lisa O'Rourke, Christopher Chiu, Sung-Soo Yoon, Mieczysław Komarnicki, Xiang Qin, Paul G. Richardson, Tahamtan Ahmadi, Mary E. Guckert, Kenshi Suzuki, Steen Lisby, Torben Plesner, Robert Z. Orlowski

المصدر: Dimopoulos, M A, Oriol, A, Nahi, H, San-Miguel, J, Bahlis, N J, Usmani, S Z, Rabin, N, Orlowski, R Z, Komarnicki, M, Suzuki, K, Plesner, T, Yoon, S-S, Ben Yehuda, D, Richardson, P G, Goldschmidt, H, Reece, D, Lisby, S, Khokhar, N Z, O'Rourke, L, Chiu, C, Qin, X, Guckert, M, Ahmadi, T, Moreau, P & POLLUX Investigators 2016, ' Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma ', The New England Journal of Medicine, vol. 375, no. 14, pp. 1319-1331 . https://doi.org/10.1056/NEJMoa1607751Test

مصطلحات موضوعية: Dexamethasone/administration & dosage, Oncology, medicine.medical_specialty, Multiple Myeloma/drug therapy, Kaplan-Meier Estimate, Antibodies, Monoclonal/administration & dosage, Disease-Free Survival, Ixazomib, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Recurrence, Internal medicine, Humans, Medicine, Elotuzumab, Lenalidomide, Multiple myeloma, Dexamethasone, Aged, Thalidomide/administration & dosage, business.industry, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Daratumumab, General Medicine, Middle Aged, Pomalidomide, medicine.disease, Interim analysis, Surgery, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, business, 030215 immunology, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a61628e9bf3047e8da229f84c6cb1962Test
https://doi.org/10.1056/nejmoa1607751Test

المؤلفون: George D. Yancopoulos, Neil M.H. Graham, Bolanle Akinlade, Marjolein S. de Bruin-Weller, Diamant Thaçi, Carlos Ferrándiz, Jonathan I. Silverberg, Zhen Chen, Gianluca Pirozzi, Lisa A. Beck, Regina Fölster-Holst, Mette Deleuran, Eric L. Simpson, Lawrence F. Eichenfield, Thomas Bieber, Marius Ardeleanu

المصدر: Eichenfield, L F, Bieber, T, Beck, L A, Simpson, E L, Thaçi, D, de Bruin-Weller, M, Deleuran, M, Silverberg, J I, Ferrandiz, C, Fölster-Holst, R, Chen, Z, Graham, N M H, Pirozzi, G, Akinlade, B, Yancopoulos, G D & Ardeleanu, M 2019, ' Infections in Dupilumab Clinical Trials in Atopic Dermatitis : A Comprehensive Pooled Analysis ', American Journal of Clinical Dermatology, vol. 20, no. 3, pp. 443-456 . https://doi.org/10.1007/s40257-019-00445-7Test
American journal of clinical dermatology, vol 20, iss 3
American Journal of Clinical Dermatology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona

مصطلحات موضوعية: Dermatitis, Dermatitis, Atopic/complications, Skin infection, Severity of Illness Index, Placebos, 030207 dermatology & venereal diseases, 0302 clinical medicine, Monoclonal, Eczema herpeticum, Placebos/administration & dosage, Original Research Article, Skin Diseases, Infectious, Humanized, Randomized Controlled Trials as Topic, Subcutaneous, Incidence, Infectious, Antibodies, Monoclonal, General Medicine, Atopic dermatitis, Dupilumab, Phase III as Topic, Treatment Outcome, Adult, medicine.medical_specialty, Injections, Subcutaneous, Clinical Sciences, Dermatology, Placebo, Antibodies, Monoclonal, Humanized, Skin Diseases, Antibodies, Monoclonal/administration & dosage, Atopic, Antibodies, Dermatitis, Atopic, Injections, 03 medical and health sciences, Pharmacotherapy, Clinical Trials, Phase II as Topic, Double-Blind Method, Internal medicine, medicine, Humans, Clinical Trials, Skin Diseases, Infectious/epidemiology, Asthma, business.industry, Dermatology & Venereal Diseases, Phase II as Topic, medicine.disease, Clinical Trials, Phase III as Topic, Relative risk, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878f5fdd0301a399436c327054e17d29Test
https://pure.au.dk/portal/da/publications/infections-in-dupilumab-clinical-trials-in-atopic-dermatitisTest(c9ddd584-7cf4-4bfd-ac98-e1c7933c8e02).html