المؤلفون: Cristina Barca, Claudia Foray, Sven Hermann, Ulrich Herrlinger, Isabel Remory, Damya Laoui, Michael Schäfers, Oliver M. Grauer, Bastian Zinnhardt, Andreas H. Jacobs

المساهمون: Supporting clinical sciences, Medical Imaging, Department of Bio-engineering Sciences, Cellular and Molecular Immunology

المصدر: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology

مصطلحات موضوعية: positron emission tomography, Receptor, Macrophage Colony-Stimulating Factor/antagonists & inhibitors, Immunology, Anti-Inflammatory Agents, Brain Neoplasms/drug therapy, Antineoplastic Agents, Receptor, Macrophage Colony-Stimulating Factor, Review, microglia/macrophages, neuroinflammation, Macrophages/drug effects, colony stimulating factor-1 receptor, Signal Transduction/drug effects, glioma, Animals, Humans, Immunology and Allergy, Anti-Inflammatory Agents/pharmacology, Microglia/drug effects, Brain Neoplasms, Macrophages, RC581-607, Neuroinflammatory Diseases/drug therapy, stroke, Disease Models, Animal, Review Literature as Topic, Neuroprotective Agents, Glioma/drug therapy, Neuroinflammatory Diseases, Disease Progression, Microglia, Immunologic diseases. Allergy, Antineoplastic Agents/pharmacology, Neuroprotective Agents/pharmacology, Stroke/drug therapy, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c71155a4e0ea75bbd889f5f0913aac5Test
https://www.frontiersin.org/articles/10.3389/fimmu.2021.787307/fullTest

المؤلفون: Andreas Janata, Kristin L. Schreiber, Caleb D Wilson, Ingrid A.M. Magnet, Tomas Drabek, Patrick M. Kochanek, Jason Stezoski, Keri Janesko-Feldman

المصدر: World Journal of Critical Care Medicine

مصطلحات موضوعية: Survival rate, medicine.medical_specialty, medicine.medical_treatment, macromolecular substances, Minocycline/pharmacology, Heart arrest/pathology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, cardiovascular diseases, Cardiopulmonary resuscitation, Microglia/drug effects, business.industry, 030208 emergency & critical care medicine, Minocycline, Basic Study, medicine.disease, Neurons/drug effects, 3. Good health, nervous system, 030228 respiratory system, Ventricular fibrillation, cardiovascular system, Cardiology, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d25add8cbf70b26671f3bd3e66fcd8Test
https://doi.org/10.5492/wjccm.v8.i7.106Test

المؤلفون: Izzettin Hatip-Al-Khatib, Funda F. Bölükbaşı Hatip, Junichi Matsumoto, Fuyuko Takata, Takashi Machida, Yasufumi Kataoka, Shinya Dohgu, Atsushi Yamauchi

المصدر: Brain Research. 1692:34-44

مصطلحات موضوعية: 0301 basic medicine, Animals, Brain/*cytology, Cells, Cultured, Dose-Response Relationship, Drug, Enzyme Inhibitors/pharmacology, Gene Expression Regulation/drug effects, I-kappa B Proteins/metabolism, Interleukin-6/*metabolism, Mice, Microglia/*drug effects, NF-kappa B, Pericytes/*drug effects, RNA, Messenger/metabolism, Rats, Rats, Wistar, STAT3 Transcription Factor/metabolism, Signal Transduction/*drug effects, Tumor Necrosis Factor-alpha/*pharmacology, microglia, animal cell, Wistar rat, STAT3, I kappa B, NF?B, 0302 clinical medicine, dose response, pericyte, rat, animal, Enzyme Inhibitors, primary culture, Microglia, biology, messenger RNA, Chemistry, brain pericyte, General Neuroscience, drug effect, neutralizing antibody, Brain, Interleukin, gene expression regulation, Tumor necrosis factor-α, cell activation, Cell biology, immunoglobulin enhancer binding protein, medicine.anatomical_structure, cytokine release, priority journal, Tumor necrosis factor-?, JAK-STAT signaling, I-kappa B Proteins, Tumor necrosis factor alpha, Pericyte, Tyrosine kinase, signal transduction, Signal Transduction, Astrocyte, STAT3 Transcription Factor, tumor necrosis factor, animal experiment, central nervous system disease, enzyme inhibitor, interleukin 6, Article, 03 medical and health sciences, STAT3 protein, medicine, RNA, Messenger, Molecular Biology, mouse, Neuroinflammation, cell culture, nonhuman, Interleukin-6, Tumor Necrosis Factor-alpha, animal cell culture, protein phosphorylation, 030104 developmental biology, receptor cross-talk, Gene Expression Regulation, gene expression, cytology, biology.protein, Neurology (clinical), Pericytes, metabolism, Janus kinase, 030217 neurology & neurosurgery, NFκB, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706aba2f546c7b20734ef8cf336638f0Test
https://doi.org/10.1016/j.brainres.2018.04.023Test

المؤلفون: Mário A. Barbosa, Teresa Summavielle, Susana G. Santos, Jaime Freitas, Joana Bravo, Maria Inês Almeida, Joao Paulo Bras

المساهمون: Instituto de Investigação e Inovação em Saúde, Repositório Científico do Instituto Politécnico do Porto

المصدر: Cell Death and Disease, Vol 11, Iss 6, Pp 1-15 (2020)
Cell Death & Disease
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Cancer Research, Gene Expression Regulation / drug effects, Neurotoxins / toxicity, Neuroimmunology, Inflammation / genetics, Tumor Necrosis Factor-alpha / pharmacology, Inflammation / pathology, Primary microglia, Microglia, lcsh:Cytology, Chemistry, Enzyme-linked immunosorbent assay (ELISA), NF-kappa B, MicroRNAs / metabolism, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, Microglia / metabolism, miRNAs, Cytokines, Tumor necrosis factor alpha, Neurotoxins, Immunology, Mixed glial cells, Context (language use), Models, Biological, Article, NF-kappa B / metabolism, Cell Line, Cellular and Molecular Neuroscience, Mediator, Downregulation and upregulation, medicine, Animals, Rats, Wistar, lcsh:QH573-671, Neuroinflammation, Inflammation, Microglia / pathology, Transcription Factors / metabolism, Tumor Necrosis Factor-alpha, Neurotoxicity, N9 microglial cells, DNA-Binding Proteins / metabolism, Cell Biology, Microglia / drug effects, medicine.disease, miR-342, Mice, Inbred C57BL, MicroRNAs, Cytokines / metabolism, MicroRNAs / genetics, Animals, Newborn, Gene Expression Regulation, nervous system, TNF-alpha-induced microglia activation, Neuron, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401f63fb9a756b8fd8925ca8ee30868bTest
https://doi.org/10.1038/s41419-020-2626-6Test

المؤلفون: Joilson Ramos-Jesus, Jand Venes R. Medeiros, André Luis Fernandes Lopes, Marcelo P. Bemquerer, Guilherme Antônio Lopes de Oliveira, Renato Socodato, Nayara A. Sousa, Luan Kelves Miranda de Souza, Eder Alves Barbosa, Thiago S.L. Araújo, Camila C. Portugal, Kerolayne M. Nogueira, Bruno Iles, Peter Eaton, Alexandra Plácido, Andrea Lobo, Alyne Rodrigues de Araújo, João B. Relvas, Yuri D. M. Campelo, José Roberto S. A. Leite, Ana Patrícia de Oliveira, Constança Pais do Amaral

المساهمون: Repositório da Universidade de Lisboa, NAYARA A. SOUSA, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBA, GUILHERME A. L. OLIVEIRA, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBA, ANA PATRÍCIA DE OLIVEIRA, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBA, ANDRÉ LUÍS F. LOPES, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBA, BRUNO ILES, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBA, KEROLAYNE M. NOGUEIRA, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBA, THIAGO S. L. ARAÚJO, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBA, LUAN K. M. SOUZA, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBA, ALYNE R. ARAÚJO, UFPI, JOILSON RAMOS-JESUS, UFPI, ALEXANDRA PLÁCIDO, FACULDADE DE CIENCIAS DA UNIVERSIDADE DO PORTO, PORTUGAL, CONSTANÇA AMARAL, UNIVERSIDADE DE LISBOA, PORTUGAL, YURI D. M. CAMPELO, FAHESP/IESVAP/NRE, EDER ALVES BARBOSA, UNB, CAMILA C. PORTUGAL, FACULDADE DE CIENCIAS DA UNIVERSIDADE DO PORTO, PORTUGAL, RENATO SOCODATO, FACULDADE DE CIENCIAS DA UNIVERSIDADE DO PORTO, PORTUGAL, ANDREA LOBO, FACULDADE DE CIENCIAS DA UNIVERSIDADE DO PORTO, PORTUGAL, JOAO RELVAS, FACULDADE DE CIENCIAS DA UNIVERSIDADE DO PORTO, PORTUGAL, MARCELO PORTO BEMQUERER, Cenargen, PETER EATON, FACULDADE DE CIENCIAS DA UNIVERSIDADE DO PORTO, PORTUGAL, JOSÉ ROBERTO S. A. LEITE, UNB, JAND VENES R. MEDEIROS, UNIVERSIDADE FEDERAL DO DELTA DO PARNAÍBA., Instituto de Investigação e Inovação em Saúde

المصدر: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Lipopolysaccharides, Lipopolysaccharide, lcsh:Medicine, ComputingMilieux_LEGALASPECTSOFCOMPUTING, Hippocampal formation, medicine.disease_cause, Hippocampus / drug effects, Hippocampus, Mice, chemistry.chemical_compound, 0302 clinical medicine, Infections / microbiology, lcsh:Science, Anura / metabolism, Neurons, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, biology, Microglia, Neurons / metabolism, Amino Acid Sequence / genetics, NF-kappa B, Antimicrobial Cationic Peptides / metabolism, Malondialdehyde, medicine.anatomical_structure, Hippocampus / metabolism, Nitrites / antagonists & inhibitors, Natural product synthesis, Anura, Antimicrobial Cationic Peptides / pharmacology, Neurons / drug effects, Infections, Cutaneous secretions, Article, Superoxide dismutase, Amphibians, 03 medical and health sciences, Nitrites / metabolism, Lipopolysaccharides / toxicity, medicine, Animals, Antimicrobial Cationic Peptides / chemistry, Amino Acid Sequence, Nitrites, 030304 developmental biology, Reactive oxygen species, Leptodactylus vastus, lcsh:R, Reactive Oxygen Species / metabolism, Glutathione, Antimicrobial Cationic Peptides / genetics, Microglia / drug effects, Molecular biology, NF-kappa B / genetics, Pharmacodynamics, chemistry, Infections / genetics, biology.protein, lcsh:Q, Infections / drug therapy, Reactive Oxygen Species, Peptides, Infections / chemically induced, 030217 neurology & neurosurgery, Oxidative stress, Antimicrobial Cationic Peptides

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c936432f2390466bc43188ee5504a1e8Test
https://hdl.handle.net/10451/47101Test

المؤلفون: Joana F. Henriques, Renata L. Alves, Ana Magalhães, Teresa Summavielle, Teresa Canedo, Camila C. Portugal, Cátia M. Silva, João B. Relvas, Renato Socodato, Tiago Almeida, Joana Tedim-Moreira

المساهمون: Instituto de Investigação e Inovação em Saúde

مصطلحات موضوعية: Male, Ethanol / administration & dosage, Synaptic pruning, Alcohol abuse, Anxiety, Synaptic Transmission, Biochemistry, Synapse, Neuronal Plasticity / drug effects, 0302 clinical medicine, Synaptic Transmission / physiology, Synapses / physiology, Tumor Necrosis Factor-alpha / metabolism, Cells, Cultured, Behavior, Animal / drug effects, Mice, Knockout, 0303 health sciences, Anxiety / psychology, Neuronal Plasticity, Behavior, Animal, Microglia, Synapses / drug effects, medicine.anatomical_structure, Neuronal Plasticity / physiology, Microglia / metabolism, Excitatory postsynaptic potential, Binge drinking, Mice, Transgenic, Neurotransmission, Behavior, Animal / physiology, Proinflammatory cytokine, 03 medical and health sciences, medicine, Animals, Humans, Synaptic Transmission / drug effects, Molecular Biology, 030304 developmental biology, Ethanol, Tumor Necrosis Factor-alpha, business.industry, Anxiety / physiopathology, Central Nervous System Depressants, Cell Biology, Microglia / drug effects, medicine.disease, Mice, Inbred C57BL, nervous system, Central Nervous System Depressants / administration & dosage, Ethanol / blood, Synapses, Microglia / cytology, business, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5323d1d38dd85484e38fe3dc3daa066Test
https://hdl.handle.net/10216/140511Test

المؤلفون: Jinglu Ai, R. L. Macdonald, Mervyn D.I. Vergouwen, Shakira Brathwaite, H Ni, Joost C. M. Meijers, H Wan, Yiming Wang, Elly M. Hol

المساهمون: Netherlands Institute for Neuroscience (NIN), ACS - Pulmonary hypertension & thrombosis, Vascular Medicine, ANS - Amsterdam Neuroscience, Experimental Vascular Medicine

المصدر: Journal of Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis, 16, 1413-1422. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 16(7), 1413. Wiley-Blackwell
Journal of thrombosis and haemostasis, 16(7), 1413-1422. Wiley-Blackwell

مصطلحات موضوعية: Male, Time Factors, Recombinant Proteins/administration & dosage, VASCULAR BIOLOGY, Apoptosis, von Willebrand factor, 030204 cardiovascular system & hematology, Inbred C57BL, Pathogenesis, Mice, 0302 clinical medicine, Interquartile range, hemic and lymphatic diseases, ADAMTS13 Protein/administration & dosage, Microglia/drug effects, Non-U.S. Gov't, Mice, Knockout, Neurons, Brain/drug effects, Hematology, biology, Caspase 3, Research Support, Non-U.S. Gov't, Brain Injuries/enzymology, Microfilament Proteins, Brain, Thrombosis, Recombinant Proteins, ADAMTS13, 3. Good health, Neuroprotective Agents/administration & dosage, Neuroprotective Agents, Phenotype, medicine.anatomical_structure, von Willebrand Factor/genetics, platelet aggregation, Cerebral cortex, Female, Original Article, Microglia, Caspase 3/metabolism, medicine.medical_specialty, Subarachnoid hemorrhage, brain diseases, subarachnoid hemorrhage, Knockout, ADAMTS13 Protein, Microfilament Proteins/metabolism, Research Support, Drug Administration Schedule, 03 medical and health sciences, Calcium-Binding Proteins/metabolism, Von Willebrand factor, Internal medicine, Journal Article, medicine, Animals, Genetic Predisposition to Disease, cardiovascular diseases, thrombosis, Animal, business.industry, Calcium-Binding Proteins, Original Articles, medicine.disease, Neurons/drug effects, Mice, Inbred C57BL, Disease Models, Animal, Endocrinology, Brain Injuries, Disease Models, Subarachnoid Hemorrhage/complications, biology.protein, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b5717ba674e50c8f0ea29e47800996Test
https://doi.org/10.1111/jth.14136Test

المؤلفون: Christopher J.R. Dunning, Tomas Deierborg, Bettina Hjelm Clausen, Yiyi Yang, Antonio Boza-Serrano, Kate Lykke Lambertsen

المصدر: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-19 (2018)
Journal of Neuroinflammation
Yang, Y, Boza-Serrano, A, Dunning, C J R, Clausen, B H, Lambertsen, K L & Deierborg, T 2018, ' Inflammation leads to distinct populations of extracellular vesicles from microglia ', Journal of Neuroinflammation, vol. 15, 168 . https://doi.org/10.1186/s12974-018-1204-7Test

مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, Male, Lipopolysaccharide, medicine.medical_treatment, TNF, Gene Expression Regulation/drug effects, Nitric Oxide Synthase Type II, lcsh:RC346-429, Etanercept, chemistry.chemical_compound, Mice, Neuroinflammation, Signal Transduction/drug effects, Microglia/drug effects, Cell Line, Transformed, Mice, Knockout, medicine.diagnostic_test, Microglia, General Neuroscience, Cytokines/metabolism, Etanercept/pharmacology, Interleukin, Infarction, Middle Cerebral Artery, Cell biology, Protein Transport, Cytokine, medicine.anatomical_structure, Neurology, Cytokines, Tumor necrosis factor alpha, medicine.symptom, Nitric Oxide Synthase Type II/metabolism, Immunosuppressive Agents, Signal Transduction, Inflammation/etiology, Immunology, Inflammation, 03 medical and health sciences, Cellular and Molecular Neuroscience, Extracellular Vesicles, Western blot, medicine, Animals, Infarction, Middle Cerebral Artery/complications, lcsh:Neurology. Diseases of the nervous system, Immunosuppressive Agents/pharmacology, Tumor Necrosis Factor-alpha, Research, Lipopolysaccharides/pharmacology, Protein Transport/drug effects, Mice, Inbred C57BL, Extracellular Vesicles/pathology, Disease Models, Animal, 030104 developmental biology, chemistry, Gene Expression Regulation, Tumor Necrosis Factor-alpha/deficiency, Extracellular vesicles (EVs)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5b9f02a66c45696b513383261ae0bfTest
http://link.springer.com/article/10.1186/s12974-018-1204-7Test

المؤلفون: Wendy Stoop, Sofie Verachtert, Peggy Verdood, Jacques De Keyser, Deborah De Geyter, Sofie Brouwers, Ron Kooijman

المساهمون: Experimental Pharmacology, Microbiology and Infection Control, Supporting clinical sciences, Clinical Biology, Faculty of Medicine and Pharmacy, Clinical Pharmacology and Clinical Pharmacy, Medicine and Pharmacy academic/administration, Clinical sciences, Neuroprotection & Neuromodulation, Basic (bio-) Medical Sciences

المصدر: Neuroscience, 348, 335-345. PERGAMON-ELSEVIER SCIENCE LTD

مصطلحات موضوعية: Male, 0301 basic medicine, STROKE-PRONE, Infarction, Blood Pressure, BRAIN-INJURY, Pharmacology, Rats, Inbred WKY, Tissue plasminogen activator, Brain Ischemia, Brain ischemia, ACTIVATION, Brain Ischemia/complications, 0302 clinical medicine, Rats, Inbred SHR, ARTERY OCCLUSION, ESTRADIOL-MEDIATED PROTECTION, rat, Microglia/drug effects, Stroke, General Neuroscience, LOCALIZATION, RECOVERY, stroke, Astrocytes/drug effects, Neuroprotective Agents, FOCAL CEREBRAL-ISCHEMIA, Anesthesia, neuroprotection, Microglia, INFARCTION, Neuroprotective Agents/pharmacology, medicine.drug, hypertension, Ischemia, Neuroprotection, Blood Pressure/drug effects, RATS, 03 medical and health sciences, Hypertension/complications, estradiol, medicine, Animals, Artery occlusion, cardiovascular diseases, HYPOTHERMIA, business.industry, medicine.disease, Estradiol/pharmacology, 030104 developmental biology, Blood pressure, Astrocytes, business, 030217 neurology & neurosurgery, Stroke/complications

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2752a6f97aab66fb70bea4b914a7cc8aTest
https://doi.org/10.1016/j.neuroscience.2017.02.040Test

المؤلفون: Philip Van Damme, Lien Beckers, Stijn Stroobants, Sander Beel, Ivana Geric, Myriam Baes, Rudi D'Hooge

المساهمون: Neurology

المصدر: Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Journal of Neuroinflammation

مصطلحات موضوعية: 0301 basic medicine, DYNAMICS, Lipopolysaccharides, Interleukin-4/administration & dosage, medicine.medical_treatment, Gene Expression Regulation/drug effects, Stimulation, Facial Nerve Diseases/complications, β-Oxidation, MULTIFUNCTIONAL PROTEIN-2, Microgliosis, Neuronal Transmission, lcsh:RC346-429, Functional Laterality, Cell Proliferation/drug effects, 0302 clinical medicine, CX3CR1, Hand Strength/physiology, Peroxisomal Multifunctional Protein-2, Microglia/drug effects, Facial nerve axotomy, Cells, Cultured, Medicine(all), ROLES, Brain/drug effects, Microglia, Hand Strength, General Neuroscience, Microfilament Proteins, LANGERHANS CELLS, Brain, DEGENERATION, INSIGHTS, medicine.anatomical_structure, Neurology, Exploratory Behavior/drug effects, Peroxisomal Multifunctional Protein-2/deficiency, Axotomy, medicine.symptom, Facial Nerve Diseases, Life Sciences & Biomedicine, CX3C Chemokine Receptor 1/metabolism, EXPRESSION, Inflammation/chemically induced, mice, Evoked Potentials, Auditory, Brain Stem/drug effects, Immunology, CX3C Chemokine Receptor 1, Conditional mouse model, Inflammation, Mice, Transgenic, Microfilament Proteins/metabolism, 03 medical and health sciences, Cellular and Molecular Neuroscience, Calcium-Binding Proteins/metabolism, In vivo, medicine, Evoked Potentials, Auditory, Brain Stem, Peroxisomes, Animals, Immune response, lcsh:Neurology. Diseases of the nervous system, Cell Proliferation, Behavior, Science & Technology, Oxidation, business.industry, Research, Calcium-Binding Proteins, Neurosciences, Disease Models, Animal, Lipopolysaccharides/toxicity, 030104 developmental biology, MAINTENANCE, Gene Expression Regulation, Animals, Newborn, IL-34, Exploratory Behavior, Neurosciences & Neurology, Interleukin-4, business, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956cabd117a620008453a8c092f71205Test
https://doi.org/10.1186/s12974-019-1442-3Test