المؤلفون: Berry, James D, Paganoni, Sabrina, Atassi, Nazem, Macklin, Eric A, Goyal, Namita, Rivner, Michael, Simpson, Ericka, Appel, Stanley, Grasso, Daniela L, Mejia, Nicte I, Mateen, Farrah, Gill, Alan, Vieira, Fernando, Tassinari, Valerie, Perrin, Steven

المصدر: Muscle & Nerve
Berry, James D; Paganoni, Sabrina; Atassi, Nazem; Macklin, Eric A; Goyal, Namita; Rivner, Michael; et al.(2017). Phase IIa trial of fingolimod for amyotrophic lateral sclerosis demonstrates acceptable acute safety and tolerability.. Muscle & nerve, 56(6), 1077-1084. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/5513221pTest

مصطلحات موضوعية: Adult, Male, circulating lymphocytes, FOXP3, RNA profiling, neuroinflammation, diagnosis, drug therapy [Amyotrophic Lateral Sclerosis], Clinical Research, Medicine and Health Sciences, Bradycardia, Humans, Single-Blind Method, adverse effects, therapeutic use [Fingolimod Hydrochloride], Fatigue, Aged, chemically induced [Bradycardia], therapeutic use [Immunosuppressive Agents], target engagement, Fingolimod Hydrochloride, Amyotrophic Lateral Sclerosis, clinical trial, Middle Aged, chemically induced [Fatigue], Female, Immunosuppressive Agents

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::691ebd15857579dada48b10620919769Test
http://europepmc.org/articles/PMC5724488Test

المؤلفون: Liu, Ganqiang, Locascio, Joseph J, Winder-Rhodes, Sophie, Vidailhet, Marie, Bonnet, Anne-Marie, Bonnet, Cecilia, Corvol, Jean-Christophe, Elbaz, Alexis, Grabli, David, Hartmann, Andreas, Klebe, Stephan, Lacomblez, Lucette, Mangone, Graziella, Tanner, Caroline M, Bourdain, Frédéric, Brandel, Jean-Philippe, Derkinderen, Pascal, Durif, Franck, Mesnage, Valérie, Pico, Fernando, Rascol, Olivier, Brefel-Courbon, Christine, Ory-Magne, Fabienne, Lang, Anthony E, Forlani, Sylvie, Lesage, Suzanne, Tahiri, Khadija, Albin, Roger, Alcalay, Roy, Ascherio, Alberto, Bowman, Dubois, Chen-Plotkin, Alice, Dawson, Ted, Eberly, Shirley, Dewey, Richard, German, Dwight, Saunders-Pullman, Rachel, Scherzer, Clemens, Vaillancourt, David, Petyuk, Vladislav, West, Andy, Zhang, Jing, Brice, Alexis, Ravina, Bernard, Shoulson, Ira, Cormier-Dequaire, Florence, Heutink, Peter, van Hilten, Jacobus J, Barker, Roger A, Williams-Gray, Caroline H, Marinus, Johan, Scherzer, Clemens R, HBS, CamPaIGN, PICNICS, PROPARK, Boot, Brendon, PSG, DIGPD, PDBP, Hyman, Bradley T, Ivinson, Adrian J, Trisini-Lipsanopoulos, Ana, Franco, Daly, Burke, Kyle, Sudarsky, Lewis R, Liao, Zhixiang, Hayes, Michael T, Umeh, Chizoba C, Sperling, Reisa, Growdon, John H, Schwarzschild, Michael A, Hung, Albert Y, Flaherty, Alice W, Blacker, Deborah, Wills, Anne-Marie, Sohur, U Shivraj, Page, Kara, Mejia, Nicte I, Viswanathan, Anand, Gomperts, Stephen N, Khurana, Vikram, Albers, Mark W, Alora-Palli, Maria, McGinnis, Scott, Sharma, Nutan, Dickerson, Bradford, Frosch, Matthew, Gomez-Isla, Teresa, Greenberg, Steven, Gusella, James, Hedden, Trey, Hedley-Whyte, E Tessa, Koenig, Aaron, Marquis-Sayagues, Marta, Marshall, Gad, Okereke, Olivia, Stemmer-Rachaminov, Anat, Kloppenburg, Jessica, Schlossmacher, Michael G, Selkoe, Dennis J, Yi, Thomas, Li, Haining, Stalberg, Gabriel, Jansen, Iris E, Barker, Roger, Foltynie, Tom, Williams-Gray, Caroline, Robbins, Trevor, Brayne, Carol, Mason, Sarah, Breen, David P, Cummins, Gemma, Evans, Jonathan, Mallet, Alain

المساهمون: Neurology, Amsterdam Neuroscience - Neurodegeneration, Human genetics

المصدر: The Lancet Neurology, 16(8), 620-629. Lancet Publishing Group
The lancet / Neurology 16(8), 620-629 (2017). doi:10.1016/S1474-4422(17)30122-9
Liu, G, Locascio, J J, Corvol, J C, Boot, B, Liao, Z, Page, K, Franco, D, Burke, K, Jansen, I E, Trisini-Lipsanopoulos, A, Winder-Rhodes, S, Tanner, C M, Lang, A E, Eberly, S, Elbaz, A, Brice, A, Mangone, G, Ravina, B, Shoulson, I, Cormier-Dequaire, F, Heutink, P, van Hilten, J J, Barker, R A, Williams-Gray, C H, Marinus, J & Scherzer, C R 2017, ' Prediction of cognition in Parkinson's disease with a clinical–genetic score : a longitudinal analysis of nine cohorts ', The Lancet Neurology, vol. 16, no. 8, pp. 620-629 . https://doi.org/10.1016/S1474-4422Test(17)30122-9
The Lancet Neurology, 16(8), 620-629

مصطلحات موضوعية: 0301 basic medicine, Gerontology, Male, medicine.medical_specialty, Population, etiology [Cognitive Dysfunction], 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Dementia, Humans, Cognitive Dysfunction, ddc:610, Longitudinal Studies, Cognitive decline, education, Aged, Proportional Hazards Models, Aged, 80 and over, education.field_of_study, Mini–Mental State Examination, Framingham Risk Score, medicine.diagnostic_test, Proportional hazards model, Hazard ratio, Parkinson Disease, Middle Aged, medicine.disease, Prognosis, diagnosis [Dementia], 030104 developmental biology, diagnosis [Cognitive Dysfunction], Quartile, Disease Progression, Female, Neurology (clinical), etiology [Dementia], complications [Parkinson Disease], Psychology, diagnosis [Parkinson Disease], 030217 neurology & neurosurgery, Algorithms

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7ad22cbe182392732b4b0ecb12076eTest
https://research.vumc.nl/en/publications/6b6b3533-b145-4979-8a44-ac24734cd334Test