المؤلفون: Sara Lopes, Thorsten Schmidt, Clévio Nóbrega, Miguel Monteiro Lopes, Dineke S. Verbeek, Diana Lobo, Dina Pereira, Ana Vasconcelos-Ferreira, Luís Pereira de Almeida, Inês Morgado Martins, Rosário Faro

المساهمون: Movement Disorder (MD), Molecular Neuroscience and Ageing Research (MOLAR)

المصدر: Molecular Therapy, 30(1), 370-387. CELL PRESS
Mol Ther

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Ataxia, Intranuclear Inclusions, Neuropathology, Mutant Huntingt, Biology, Neuroprotection, Mice, Cerebellar-Aaxiagene-Productcell-Lines, Drug Discovery, Genetics, medicine, Transcriptional regulation, Nuclear-Localization, Autophagy, Animals, Ataxin-3, Molecular Biology, Pharmacology, ULK2, Machado-Joseph Disease, ULK1, Dependovirus, medicine.disease, Cell biology, Disease Models, Animal, Molecular Medicine, Original Article, Polyglutamine-Expanded Ataxin-3, Rat Modelin-Vitro, medicine.symptom, Machado–Joseph disease

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6624ead970bd32025df3f2fed67eab6Test
https://hdl.handle.net/11370/6e7d478b-8917-4de9-ba98-76e5ef115fc2Test

المؤلفون: Contessotto, Miriam Gisele Gasparotto, 1972, Garcia, Maria Cristina Cabral, Oliveira, Cristiano Luis Pinto de, 1975, Torriani, Iris Concepcion Linares de, 1934, Lopes-Cendes, Íscia Teresinha, 1964, Murai, Marcelo Jun, 1978

المساهمون: UNIVERSIDADE ESTADUAL DE CAMPINAS

المصدر: Repositório Institucional da Unicamp
Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
Repositório da Produção Científica e Intelectual da Unicamp

مصطلحات موضوعية: Doença de Machado-Joseph, Expanded ataxin-3, Machado-Joseph disease, Small-angle X-ray scattering, Artigo original, Ataxia, Raios X - Espalhamento a baixo ângulo

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3888209f15dcce4c49e8bbf2e03113caTest

المؤلفون: Sandra Macedo-Ribeiro, Luís Pereira de Almeida, Bruno Almeida, Clévio Nóbrega, Susana R. Louros, Ana Luísa Carvalho, Elisabete Ferreiro, Jorge Valero, Carlos A. Matos

المساهمون: Instituto de Investigação e Inovação em Saúde

المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
The Journal of Cell Biology
Europe PubMed Central

مصطلحات موضوعية: Male, 0301 basic medicine, Time Factors, medicine.disease_cause, Synapse, Serine, 0302 clinical medicine, Transgenic mice, Phosphorylation, Ataxin-3, Mutant ataxin-3, Research Articles, Cerebral Cortex, Neurons, Mutation, Machado-Joseph Disease, Cell biology, Expanded ataxin-3, Biochemistry, Spinocerebellar ataxia, Rat model, RNA Interference, Protein ataxin-3, Machado–Joseph disease, Signal Transduction, congenital, hereditary, and neonatal diseases and abnormalities, Molecular Sequence Data, Gestational Age, Biology, Transfection, Neuroprotection, Article, 03 medical and health sciences, medicine, Animals, Humans, Amino Acid Sequence, Rats, Wistar, Cell Biology, Repeat expansion, Fibroblasts, medicine.disease, Clinical-features, Repressor Proteins, Disease Models, Animal, Polyglutamine disease, HEK293 Cells, 030104 developmental biology, nervous system, Ataxin, Machado-joseph-disease, Nerve Degeneration, Synapses, Huntingtin phosphorylation, Peptides, 030217 neurology & neurosurgery

وصف الملف: application/pdf; text/plain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa8599ef81658f39793e775da0d11fcTest
https://hdl.handle.net/10216/108249Test

المؤلفون: Yi Hsin Weng, Tu Hsueh Yeh, Hung Li Wang, Si Ying Chen, An Hsun Chou

المصدر: Neurobiology of Disease, Vol 41, Iss 2, Pp 481-488 (2011)

مصطلحات موضوعية: Transcriptional Activation, Genetically modified mouse, Cerebellum, congenital, hereditary, and neonatal diseases and abnormalities, Transgene, Down-Regulation, Mice, Transgenic, Nerve Tissue Proteins, Histone Deacetylases, lcsh:RC321-571, Mice, chemistry.chemical_compound, Downregulation and upregulation, Spinocerebellar ataxia type 3, medicine, Animals, Histone deacetylase, Enzyme Inhibitors, Polyglutamine-expanded ataxin-3, Ataxin-3, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Ataxin-1, biology, Nuclear Proteins, Acetylation, Sodium butyrate, Machado-Joseph Disease, Histone acetyltransferase, Molecular biology, Cell biology, Repressor Proteins, Phenotype, Histone, medicine.anatomical_structure, Ataxins, Neurology, chemistry, SCA3 transgenic mice, biology.protein, Butyric Acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764adb266c7489328157913970c7d266Test
http://www.sciencedirect.com/science/article/pii/S0969996110003530Test

المؤلفون: Tu Hsueh Yeh, Hung Li Wang, Pin Ouyang, Ying Ling Chen, Si Ying Chen, An Hsun Chou

المصدر: Neurobiology of Disease, Vol 31, Iss 1, Pp 89-101 (2008)

مصطلحات موضوعية: Genetically modified mouse, Cerebellum, Ataxia, Transcription, Genetic, Transgene, Blotting, Western, Gene Expression, Mice, Transgenic, Substantia nigra, Biology, lcsh:RC321-571, Mice, Spinocerebellar ataxia type 3, Heat shock protein, medicine, Animals, Humans, RNA, Messenger, Polyglutamine-expanded ataxin-3, Ataxin-3, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Oligonucleotide Array Sequence Analysis, Reverse Transcriptase Polymerase Chain Reaction, Neurodegeneration, Nuclear Proteins, Microarray analysis, Machado-Joseph Disease, medicine.disease, Immunohistochemistry, Molecular biology, Cell biology, Blotting, Southern, Disease Models, Animal, medicine.anatomical_structure, Neurology, nervous system, Ataxin, SCA3 transgenic mice, medicine.symptom, Peptides, Trinucleotide Repeat Expansion, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fdf1f8f122593d4685fa8d75ff9efdTest
http://www.sciencedirect.com/science/article/pii/S0969996108000673Test

المؤلفون: Shu Ru Tsai, Mei Jie Jou, An Hsun Chou, Akira Kakizuka, Yu Cheng Kao, Hung Li Wang, Yu Li Kuo, Chia Yu Hsu, Tu Hsueh Yeh

المصدر: Neurobiology of Disease, Vol 21, Iss 2, Pp 333-345 (2006)

مصطلحات موضوعية: Cerebellum, Blotting, Western, bcl-X Protein, Down-Regulation, Bcl-xL, Substantia nigra, Nerve Tissue Proteins, Apoptosis, lcsh:RC321-571, Downregulation and upregulation, Spinocerebellar ataxia type 3, medicine, In Situ Nick-End Labeling, Animals, Spinocerebellar Ataxias, RNA, Messenger, Polyglutamine-expanded ataxin-3, Ataxin-3, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Cells, Cultured, bcl-2-Associated X Protein, Neurons, TUNEL assay, biology, Reverse Transcriptase Polymerase Chain Reaction, Brain, Nuclear Proteins, medicine.disease, Molecular biology, Mitochondria, Rats, Up-Regulation, Repressor Proteins, Disease Models, Animal, medicine.anatomical_structure, Neurology, nervous system, Bax, Ataxin, Polyglutamine neurodegenerative disorders, Mutation, biology.protein, Spinocerebellar ataxia, Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3d5d13429a6fd76667d9d2033e65a3Test
http://www.sciencedirect.com/science/article/pii/S0969996105002123Test