Multimodal Breast Phantoms for Microwave, Ultrasound, Mammography, Magnetic Resonance and Computed Tomography Imaging

التفاصيل البيبلوغرافية
العنوان: Multimodal Breast Phantoms for Microwave, Ultrasound, Mammography, Magnetic Resonance and Computed Tomography Imaging
المؤلفون: Jennie Cooke, Gaia Fiaschetti, Antonio Cuccaro, Giuseppe Ruvio, Andrew J. Fagan, Jacinta E. Browne, Raffaele Solimene, Seán Cournane, Jorge A. Tobon, Max J. Ammann
المساهمون: Ruvio, Giuseppe, Solimene, Raffaele, Cuccaro, Antonio, Fiaschetti, Gaia, Fagan, Andrew J, Cournane, Sean, Cooke, Jennie, Amman, J. Max, Tobon, Jorge, Browne, Jacinta E.
المصدر: Sensors (Basel, Switzerland)
Sensors
Volume 20
Issue 8
Sensors, Vol 20, Iss 2400, p 2400 (2020)
بيانات النشر: MDPI, 2020.
سنة النشر: 2020
مصطلحات موضوعية: Computer science, Computed tomography, 02 engineering and technology, tissue-mimicking materials, lcsh:Chemical technology, Biochemistry, Article, 030218 nuclear medicine & medical imaging, Analytical Chemistry, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, 0202 electrical engineering, electronic engineering, information engineering, medicine, Medical imaging, Image Processing, Computer-Assisted, Mammography, Humans, lcsh:TP1-1185, Computer Simulation, Breast, Electrical and Electronic Engineering, Microwaves, Instrumentation, dielectric propertie, Ultrasonography, Modality (human–computer interaction), medicine.diagnostic_test, business.industry, Phantoms, Imaging, Ultrasound, 020206 networking & telecommunications, Magnetic resonance imaging, Fibroglandular Tissue, medicine.disease, Magnetic Resonance Imaging, Atomic and Molecular Physics, and Optics, Microwave imaging, dielectric properties, microwave imaging, Female, business, Tomography, X-Ray Computed, Algorithms, Biomedical engineering
الوصف: The aim of this work was to develop multimodal anthropomorphic breast phantoms suitable for evaluating the imaging performance of a recently-introduced Microwave Imaging (MWI) technique in comparison to the established diagnostic imaging modalities of Magnetic Resonance Imaging (MRI), Ultrasound (US), mammography and Computed Tomography (CT). MWI is an emerging technique with significant potential to supplement established imaging techniques to improve diagnostic confidence for breast cancer detection. To date, numerical simulations have been used to assess the different MWI scanning and image reconstruction algorithms in current use, while only a few clinical trials have been conducted. To bridge the gap between the numerical simulation environment and a more realistic diagnostic scenario, anthropomorphic phantoms which mimic breast tissues in terms of their heterogeneity, anatomy, morphology, and mechanical and dielectric characteristics, may be used. Key in this regard is achieving realism in the imaging appearance of the different healthy and pathologic tissue types for each of the modalities, taking into consideration the differing imaging and contrast mechanisms for each modality. Suitable phantoms can thus be used by radiologists to correlate image findings between the emerging MWI technique and the more familiar images generated by the conventional modalities. Two phantoms were developed in this study, representing difficult-to-image and easy-to-image patients: the former contained a complex boundary between the mammary fat and fibroglandular tissues, extracted from real patient MRI datasets, while the latter contained a simpler and less morphologically accurate interface. Both phantoms were otherwise identical, with tissue-mimicking materials (TMMs) developed to mimic skin, subcutaneous fat, fibroglandular tissue, tumor and pectoral muscle. The phantoms&rsquo
construction used non-toxic materials, and they were inexpensive and relatively easy to manufacture. Both phantoms were scanned using conventional modalities (MRI, US, mammography and CT) and a recently introduced MWI radar detection procedure called in-coherent Multiple Signal Classification (I-MUSIC). Clinically realistic artifact-free images of the anthropomorphic breast phantoms were obtained using the conventional imaging techniques as well as the emerging technique of MWI.
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67eb85cdb90e00fe86280fcbe6703fbTest
http://hdl.handle.net/11583/2816092Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....a67eb85cdb90e00fe86280fcbe6703fb
قاعدة البيانات: OpenAIRE