نتائج البحث - "ANGIOPLASTY"

81

TIMI flow and myocardial blushing after rescue PCI and cardiac magnetic resonance: Results from the Myocardial Salvage After Rescue Angioplasty: Evaluation by Magnetic Resonance (SAVE-ME) study

المؤلفون: Francesco, Moroni, Lorenzo, Azzalini, Adriano, Caixeta, Thiago P, Oliveira, Luiz F, Ybarra

المصدر: International Journal of Cardiology. 369:77-79

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Angioplasty, Blushing, Contrast Media, Gadolinium, Stroke Volume, Coronary Angiography, Magnetic Resonance Imaging, Ventricular Function, Left, Percutaneous Coronary Intervention, Treatment Outcome, Coronary Circulation, Humans, ST Elevation Myocardial Infarction, Cardiology and Cardiovascular Medicine

الوصف: Thrombolysis is currently reserved for ST-elevation myocardial infarction (STEMI) patients who cannot access timely percutaneous coronary intervention (PCI). In case of failed thrombolysis, rescue PCI is a viable option. Substantial data concerning the outcomes in terms of infarct size and myocardial function after rescue PCI are lacking.Forty patients treated with rescue PCI underwent serial contrast-enhanced cardiac magnetic resonance imaging (CMR) at 1 week, 3 months and 6 months from the index STEMI. Angiographic images were reviewed to assess Thrombolysis in Myocardial Infarction (TIMI) blood flow and TIMI Myocardial Blush Grade (TMBG) in the infarct related artery after PCI.Patients with lower TMBG at the end of procedure, but not patients with worse TIMI flow, had lower left ventricular ejection fraction (LVEF) and higher volume of late gadolinium enhancement (LGE) on baseline CMR (44 ± 13% vs 52 ± 9%, p = 0.026, and 41 ± 21 ml vs 26 ± 12, p = 0.030, respectively). Patients with lower TMBG remained with significantly lower LVEF at 6 months follow up (48 ± 16% vs 59 ± 14, p = 0.049).TMBG after rescue PCI is associated with reduced LVEF and increased LGE burden. As TMBG is a known marker of microvascular damage after STEMI, novel strategies aimed at improving microvascular function in the setting of rescue PCI are needed to improve the outcomes in this patient population.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3046b45be897e185a24d250906c76954Test
https://doi.org/10.1016/j.ijcard.2022.08.014Test

82

Effect of coarctation of aorta anatomy and balloon profile on the outcome of balloon angioplasty in infantile coarctation

المؤلفون: Hamid Amoozgar, Narjes Nouri, Sajad Shabanpourhaghighi, Neda Bagherian, Nima Mehdizadegan, Mohammad Reza Edraki, Amir Naghshzan, Hamid Mohammadi, Gholamhossein Ajami, Ashkan Abdollahi

المصدر: BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Cardiovascular Disorders

الوصف: Objective Coarctation of the Aorta (CoA) is a relatively common cardiovascular disorder. The present study aimed to evaluate the effect of COA anatomy and high versus low-pressure balloons on the outcome of balloon angioplasty among neonates and infants. Methods In this retrospective study, the neonates and infants undergoing balloon angioplasty at Namazi hospital were enrolled. After balloon angioplasty, immediate data results were promptly recorded.Moreover, midterm echocardiographic information was collected via electronic cardiac records of pediatric wards and clinical and echocardiographic data at least 12 months after balloon angioplasty. Finally, data were analyzed using SPSS-20. Results In this study, 42 infants were included. The median age at the time of balloon angioplasty was 1.55 (range 0.1–12) months and 66.7% of the patients were male. The mean pressure gradient of coarctation was 38.49 ± 24.97 mmHg, which decreased to 7.61 ± 8.00 mmHg (P Conclusion Recoarctation rate was lower in the high-pressure balloon. The infant with discrete COA had a better response to the balloon with more decrease in gradient and lower recoarctation rate. Therefore, the stenotic segment anatomy needs to be considered in the selection of treatment methods.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202934349a80fe4e7031239c1693a741Test
https://doaj.org/article/c8981a0f88c5482280a1df8b18af1d8aTest

83

Portal vein obstruction after pediatric liver transplantation

المؤلفون: Hubert P. J. van der Doef, Bader A Alfares, Henkjan J. Verkade, Stéphanie Franchi-Abella, Ruben H J de Kleine, Reinoud P H Bokkers, Girish Gupte, Rudi Dierckx

المصدر: Transplantation Reviews. 35(4):1-8

مصطلحات موضوعية: Gastrointestinal bleeding, medicine.medical_specialty, medicine.medical_treatment, CHILDREN, 030230 surgery, Splenic artery, Liver transplantation, STENOSIS, 03 medical and health sciences, 0302 clinical medicine, Biliary atresia, Angioplasty, medicine.artery, Ascites, medicine, Humans, Embolization, Child, ANGIOPLASTY, SHUNT, Vascular Patency, Stent placement, Transplantation, COMPLICATIONS, HYPERTENSION, Portal Vein, business.industry, Endovascular recanalization, Percutaneous transluminal angioplasty, medicine.disease, Portal vein obstruction, Liver Transplantation, Surgery, Mesorex bypass, THROMBOSIS, Systematic review, Portal hypertension, REX, Stents, 030211 gastroenterology & hepatology, medicine.symptom, business, INTERVENTION

الوصف: Introduction Portal vein obstruction (PVO) is a significant vascular complication after liver transplantation (LT) in pediatric patients. Current treatment strategies include percutaneous transluminal angioplasty (PTA), with or without stent placement, mesorex bypass (MRB), splenorenal shunt, mesocaval shunt, endovascular recanalization (EVR), splenic artery embolization and splenectomy. However, specific characteristics of patients undergoing intervention and selection of individual treatment and its efficacy have remained unclear. This review systematically analyzed biochemical and clinical characteristics, selection of treatment, efficacy, and post-procedural complications. Methods We systematically searched PubMed and Embase between January 1995 and March 2021 for studies on the management of PVO after LT. We analyzed the reports for biochemical and clinical characteristics at the timing of the intervention in different patients, selection of treatment, and reported efficacies. Results We found 22 cohort studies with 362 patients who had the following characteristics: biliary atresia (83%), living-donor LT (85%), thrombocytopenia (73%), splenomegaly (40%), ascites (16%), or gastrointestinal bleeding (26%). The 3-year primary patency of PTA without stent placement was similar to that with stent placement (70%–80% and 43%–94%, respectively). MRB was used as an initial treatment with a 3-year patency of 75% to 100%. One study showed that 5-year primary patency of EVR was 80%. Secondary patency was 90% to 100% after 3 years in all studies with PTA alone, PTA/stent placement, and stent placement alone. Conclusion This is the first review of all treatment protocols in PVO after pediatric LT. We showed that an important group of patients has severe symptoms of portal hypertension. Efficacy of all treatment modalities was high in the included studies which make them important modalities for these patients.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805156d2f65bc03cca6c7b85e475b80cTest
https://doi.org/10.1016/j.trre.2021.100630Test

84

Balloon pulmonary angioplasty combined with riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (PRACTICE study): study protocol for a randomized controlled trial

المؤلفون: Qin-Hua Zhao, Su-Gang Gong, Jing He, Ping Yuan, Wen-Hui Wu, Ci-Jun Luo, Rong Jiang, Rui Zhang, Hong-Ling Qiu, Hui-Ting Li, Yuan Li, Jin-Ming Liu, Lan Wang

المصدر: Trials, Vol 22, Iss 1, Pp 1-7 (2021)
Trials

مصطلحات موضوعية: Riociguat, Medicine (General), Hypertension, Pulmonary, Medicine (miscellaneous), Study Protocol, Pyrimidines, Balloon pulmonary Angioplasty, R5-920, Randomized controlled trial, Chronic Disease, Humans, Pyrazoles, Pharmacology (medical), Pulmonary Embolism, Angioplasty, Balloon, Randomized Controlled Trials as Topic, Chronic thromboembolic Pulmonary hypertension

الوصف: Background Management of inoperable chronic thromboembolic pulmonary hypertension (CTEPH) remains a clinical challenge. Currently, riociguat, a soluble guanylate-cyclase stimulator is recommended by international guidelines. More recently, balloon pulmonary angioplasty (BPA) develops as an alternative treatment for inoperable CTEPH. Method This study is a single-center randomized controlled trial. Subjects with inoperable CTEPH are randomized into either a BPA combined with riociguat or riociguat monotherapy group (2:1) and observed for 12 months after initiation of treatment. The primary endpoint is the change in pulmonary vascular resistance from baseline to 12 months after initiation of treatment. The secondary endpoints include 6-min walk distance (6MWD), WHO-FC, NT-proBNP, SF-36, and other hemodynamic parameters. Safety endpoints are analyzed too. Discussion This study aims to compare the efficacy and safety of BPA combined with riociguat and riociguat monotherapy for inoperable CTEPH. Trial registration Chinese Clinical Trial Registry ChiCTR2000032403. Registered on 27 April 2020.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa2fce6d06b6a1bb9321fce08f248ccTest
https://doaj.org/article/79cb40013f634c76956e1ebeb61bd0dfTest

85

Effect of temperature-sensitive nanogel combined with angioplasty on sICAM-1 and VE-cadherin in lower extremity arterial occlusion rabbits

المؤلفون: Ming Qi, Ze Song, Lei Wang, Xu Xie

المصدر: Bioengineered, Vol 12, Iss 2, Pp 12535-12543 (2021)
Bioengineered
article-version (VoR) Version of Record

الوصف: The study was to explore the effect of subintimal angioplasty (SIA) on the levels of soluble intercellular adhesion molecule-1 (sICAM-1) and vascular endothelial cadherin (VE-cadherin) in the rabbit model of lower extremity arterial occlusion. Specifically, the poly(N-isopropylacrylamide-co-butyl methacrylate) (PIB) temperature-sensitive nanogel was prepared, and the cytotoxicity of direct and indirect contact with PIB temperature-sensitive gel was analyzed then. Subsequently, the PIB temperature-sensitive gel was injected to the New Zealand white rabbit to prepare the lower extremity arterial occlusion model. The healthy control, model group, and SIA group were compared for the serum lipids, fibrinogen (Fbg), fibrinogen (Fbg), and fibrinogen (Fbg) levels. The results showed that the cell proliferation activity and survival rate were always higher than 90% under different concentrations of PIB temperature-sensitive gels. Compared with the model group, the SIA group had increased total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), and Fbg levels, but decreased high-density lipoprotein (HDL) level (P

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868755248f0641a71968e8e6710e1f83Test
https://doaj.org/article/099fc8c86f794ed3a0ea3630f9e948a2Test

86

Portal vein obstruction after pediatric liver transplantation

المصدر: Transplantation Reviews. 35(4):1-8

مصطلحات موضوعية: Stent placement, COMPLICATIONS, HYPERTENSION, Endovascular recanalization, CHILDREN, Percutaneous transluminal angioplasty, Portal vein obstruction, STENOSIS, Mesorex bypass, THROMBOSIS, Systematic review, REX, ANGIOPLASTY, SHUNT, INTERVENTION, STENT PLACEMENT

الوصف: INTRODUCTION: Portal vein obstruction (PVO) is a significant vascular complication after liver transplantation (LT) in pediatric patients. Current treatment strategies include percutaneous transluminal angioplasty (PTA), with or without stent placement, mesorex bypass (MRB), splenorenal shunt, mesocaval shunt, endovascular recanalization (EVR), splenic artery embolization and splenectomy. However, specific characteristics of patients undergoing intervention and selection of individual treatment and its efficacy have remained unclear. This review systematically analyzed biochemical and clinical characteristics, selection of treatment, efficacy, and post-procedural complications.METHODS: We systematically searched PubMed and Embase between January 1995 and March 2021 for studies on the management of PVO after LT. We analyzed the reports for biochemical and clinical characteristics at the timing of the intervention in different patients, selection of treatment, and reported efficacies.RESULTS: We found 22 cohort studies with 362 patients who had the following characteristics: biliary atresia (83%), living-donor LT (85%), thrombocytopenia (73%), splenomegaly (40%), ascites (16%), or gastrointestinal bleeding (26%). The 3-year primary patency of PTA without stent placement was similar to that with stent placement (70%-80% and 43%-94%, respectively). MRB was used as an initial treatment with a 3-year patency of 75% to 100%. One study showed that 5-year primary patency of EVR was 80%. Secondary patency was 90% to 100% after 3 years in all studies with PTA alone, PTA/stent placement, and stent placement alone.CONCLUSION: This is the first review of all treatment protocols in PVO after pediatric LT. We showed that an important group of patients has severe symptoms of portal hypertension. Efficacy of all treatment modalities was high in the included studies which make them important modalities for these patients.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dris___01423::8f765cf40e172292760ad39de6230778Test
https://doi.org/10.1016/j.trre.2021.100630Test

87

Drug-Coated Balloon-Only Angioplasty Outcomes in Diabetic and Nondiabetic Patients with De Novo Small Coronary Vessels Disease

المؤلفون: Yingguang Shan, Botey Katamu Benjamin, Guoju Sun, Peng Qin, Zhanying Han, Xule Wang, Sen Guo, Xi Wang, Liang Pan, Shuai Zhou, Xiaolin Zheng, Ran Li, Qiangwei Shi, Xiaofei Qin, Chunguang Qiu, Wenjie Lu, Chhatra Pratap Singh, Wencai Zhang, Jianzeng Dong

المصدر: Journal of Interventional Cardiology
Journal of Interventional Cardiology, Vol 2021 (2021)

الوصف: Background. The revascularization of small vessels using drug-eluting stents remains challenging. The use of the drug-coated balloon is an attractive therapeutic strategy in de novo lesions in small coronary vessels, particularly in the diabetic group. This study aimed to assess the outcomes of DCB-only angioplasty in small vessel disease. Methods. A total of 1198 patients with small vessel disease treated with DCB-only strategy were followed. Patients were divided into the diabetic and nondiabetic groups. Clinical and angiographical follow-up were organized at 12 months. The primary endpoints were target lesion failure and secondary major adverse cardiac events. Results. There was a significantly higher rate of target lesion failure among diabetic patients compared to nondiabetic [17 (3.9%) vs. 11 (1.4%), P = 0.006 ], taken separately, the rate of target lesion revascularization significantly differed between groups with a higher rate observed in the diabetic group [9 (2%) vs. 4 (0.5%), P = 0.014 ]. Diabetes mellitus remained an independent predictor for TLF (HR: 2.712, CI: 1.254–5.864, P = 0.011 ) and target lesion revascularization (HR: 3.698, CI: 1.112–12.298, P = 0.033 ) after adjustment. However, no significant differences were observed between groups regarding the target vessel myocardial infarction (0.6% vs. 0.1%, P = 0.110 ) and MACE [19 (4.4%) vs. 21 (2.7%), P = 0.120 ]. Conclusion. Drug-coated balloon-only treatment achieved lower incidence rates of TLF and MACE. Diabetes is an independent predictor for target lesion failure and target lesion revascularization at one year following DCB treatment in small coronary vessels. We observed no significant differences between groups regarding MACE in one year.

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الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4f050327f9951d93833392f025c3a9Test
https://doi.org/10.1155/2021/2632343Test

88

Cutting Balloon Combined with Drug-Coated Balloon Angioplasty for the Treatment of In-Stent Restenosis

المؤلفون: Chien-Jen Chen, Wei-Chieh Lee, Chiung-Jen Wu, Cheng-Hsu Yang, Chih-Yuan Fang, Hsiu-Yu Fang, You-Cheng Zheng

المصدر: International Heart Journal. 62:1213-1220

الوصف: Drug-coated balloon (DCB) has emerged as an alternative therapeutic choice for in-stent restenosis (ISR) lesions. Cutting balloon angioplasty (CBA) is also a strategy utilized to treat tight stenotic lesions or ISR lesions. Few studies have focused on whether CBA plus DCB could achieve a better result in lowering the incidence of recurrent ISR. This study aimed to evaluate the efficacy of CBA plus DCB for ISR lesions.Between August 2011 and December 2017, 681 patients (937 lesions) were diagnosed with ISR and treated with DCBs in our hospital. The CBA plus DCB group comprised 90 patients who underwent PCI with further CBA plus DCB, and the DCB alone group comprised 591 patients who underwent percutaneous coronary intervention (PCI) with DCB alone.Baseline characteristics, the types of previous stents, lesion type, prevalence of ostial lesion and left main lesion, and pre-PCI and post-PCI stenotic percentage showed no significant difference between the two groups. Only post-PCI reference luminal diameter and size of DCB were larger in the CBA plus DCB group. During the one-year follow-up period, late loss and clinical outcomes did not differ between the two groups before and after propensity score matching. The incidence of subtotal/total occlusion with delay flow was lower in the CBA plus DCB group after propensity score matching (4.1% versus 10.9%; P = 0.030).In these patients with ISR lesions, the clinical outcomes and the incidence of repeat target lesion revascularization were similar after treatment with CBA plus DCB versus DCB alone. Further study is warranted, including prospective, randomized comparisons.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6bba07b2c11df13ad630a3905b6dd7Test
https://doi.org/10.1536/ihj.21-207Test

89

Arterial Preparation by Longitudinal Micro-Incisions Before Balloon Angioplasty of the Superficial Femoral and Popliteal Artery: Acute and 12-Month Results

المؤلفون: Caroline Krieger, Rolf P. Engelberger, Jean-Baptiste Dexpert, Daniel Périard, Daniel Hayoz, Marie-Antoinette Rey Meyer

المصدر: Journal of Endovascular Therapy. 29:420-426

الوصف: Purpose: Percutaneous transluminal angioplasty (PTA) with conventional plain old balloon (POBA) and/or drug-coated balloon (DCB) is the primary intervention to treat peripheral artery stenoses. However, acute dissections during the procedure and potential for future target lesion revascularization remain procedural complications. The purpose of this study was to assess the acute and 12-month outcomes in patients who underwent novel vessel preparation with longitudinal, controlled-depth micro-incisions prior to PTA. Materials and Methods: Patients with symptomatic lower extremity peripheral arterial disease with a Rutherford class of 2 to 6 and >70% de novo stenosis of the superficial femoral or popliteal arteries were included in this retrospective study. Patients with thrombotic or embolic lesions, restenosis, or in-stent restenosis were excluded. The FLEX Vessel Prep System (FLEX VP) was used to prepare the vessel prior to PTA by creating micro-incisions at the target lesion. The FLEX VP was followed by POBA or paclitaxel DCB. Results: The study included 65 patients. Lesion characteristics were 90% median stenosis (range = 70%–100%), 75.4% mild-to-severe calcifications, and 33.8% occlusion rate, and median lesion length was 196 (range = 10–480) mm. Following vessel preparation, 82.1% of the patients had low severity dissection or no flow-limiting dissection. The provisional stent rate postprocedure was 16.9%, with a median stent length of 60 mm. The freedom from target lesion revascularization (FFTLR) in 63 evaluable patients at 6 and 12 months was 98.4% and 93.7%, respectively. Freedom from amputation was 100%. Conclusion: In this real-world/all-comers patient population with long, stenotic lesions across the calcification spectrum, vessel preparation with longitudinal micro-incisions prior to PTA was associated with low dissection rate, low dissection severity, low stent implantation, and high FFTLR with the absence of amputation at 12 months relative to published reports in long-lesion cohorts. These results support vessel preparation via micro-incisions.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1802dc021ad62b98ce9176ebb44af7a8Test
https://doi.org/10.1177/15266028211057089Test

90

Delphi Consensus Study Toward a Comprehensive Classification System for Angioplasty-Induced Femoropopliteal Dissection

المؤلفون: Alexandra O Stathis, Michiel T. Voûte, Peter Schneider, Marianne Brodmann, Ehrin J. Armstrong, Ramon L. Varcoe, Shannon D. Thomas, Andrew Holden

المصدر: JACC: Cardiovascular Interventions. 14:2391-2401

مصطلحات موضوعية: medicine.medical_specialty, Adverse outcomes, business.industry, medicine.medical_treatment, medicine.disease, % diameter reduction, Percutaneous angioplasty, Dissection, Restenosis, Angioplasty, medicine, Radiology, Cardiology and Cardiovascular Medicine, Artery dissection, business, computer, Delphi, computer.programming_language

الوصف: Objectives The aim of this study was to seek expert consensus regarding the features that predict adverse outcomes in order to develop a dedicated angiographic classification system for femoropopliteal artery dissection. Background Dissection of the femoral and popliteal arteries is common after percutaneous angioplasty. Its classification is important. However, all current classification systems have significant limitations. Methods Delphi consensus methodology was performed over 3 rounds, using an expert panel of 17 interventionalists. Each was asked to rank dissection features with the potential to lead to acute technical failure and/or early restenosis and then which combination of features would require the placement of a metallic scaffold to avoid those outcomes. Results were used to develop a novel grading system and dissection treatment algorithm. Results Four main characteristics were identified from a comprehensive preliminary list. There was a good level of agreement between panelists from 773 responses (48 combinations). All panelists recommended scaffolding if a dissection produced a ≥50% diameter reduction (100%). Most recommended scaffolding if the dissection had a spiral shape (73%-100%), was severely flow limiting (93%-100%), or had complex morphology defined by long and multiple dissections (65%-100%). Multiple combinations of those features were more likely to receive a recommendation to scaffold. Conclusions Scaffolding of a postangioplasty dissection is recommended in the presence of significant diameter reduction, spiral shape, flow impairment, or adverse morphology (DISFORM). The DISFORM classification system has been developed as a tool to provide uniform language to standardize reporting and for discussion of dissection treatment and prognosis.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a7abfb9e8b987a866de2015e4c628ca0Test
https://doi.org/10.1016/j.jcin.2021.07.056Test

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