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المؤلفون: Manoj Kumar, Manasa P Srikanth, Michela Deleidi, Penelope J Hallett, Ole Isacson, Ricardo A Feldman
المصدر: Human molecular genetics 32(11), 1888-1900 (2023). doi:10.1093/hmg/ddad025
مصطلحات موضوعية: Acid Ceramidase, metabolism [Parkinson Disease], Mechanistic Target of Rapamycin Complex 1, genetics [Glucosylceramidase], metabolism [Lysosomes], ddc:570, Genetics, Humans, metabolism [alpha-Synuclein], metabolism [Glucosylceramidase], Molecular Biology, Genetics (clinical), TOR Serine-Threonine Kinases, metabolism [Dopaminergic Neurons], genetics [Mechanistic Target of Rapamycin Complex 1], MTOR Inhibitors, General Medicine, genetics [TOR Serine-Threonine Kinases], genetics [Acid Ceramidase], metabolism [Induced Pluripotent Stem Cells], metabolism [Gaucher Disease], Mutation, genetics [alpha-Synuclein], alpha-Synuclein, Glucosylceramidase, metabolism [Acid Ceramidase]
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e623d80d2d569f3311782fe53a2d787Test
https://doi.org/10.1093/hmg/ddad025Test -
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المؤلفون: Laura C. Gunder, Tyra H. Moyer, Hillary R. Johnson, Andrew S. Auyeung, Glen E. Leverson, Wei Zhang, Kristina A. Matkowskyj, Evie H. Carchman
المصدر: Journal of Surgical Research. 282:137-146
مصطلحات موضوعية: Male, Mice, Phosphatidylinositol 3-Kinases, 9,10-Dimethyl-1,2-benzanthracene, TOR Serine-Threonine Kinases, Carcinoma, Squamous Cell, Animals, Anal Canal, Surgery, MTOR Inhibitors, Anus Neoplasms
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb6ffa178c4fa1a9df2726a4613d7deTest
https://doi.org/10.1016/j.jss.2022.09.025Test -
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المؤلفون: Sunjae Bae, Jennifer L. Alejo, Teresa P.Y. Chiang, William A. Werbel, Aaron A.R. Tobian, Linda W. Moore, Ashrith Guha, Howard J. Huang, Richard J. Knight, A. Osama Gaber, R. Mark Ghobrial, Mara A. McAdams-DeMarco, Dorry L. Segev
المصدر: American Journal of Transplantation. 22:3137-3142
مصطلحات موضوعية: Graft Rejection, Immunosuppression Therapy, Transplantation, COVID-19 Vaccines, SARS-CoV-2, TOR Serine-Threonine Kinases, COVID-19, MTOR Inhibitors, Mycophenolic Acid, Kidney Transplantation, Tacrolimus, Transplant Recipients, Antibody Formation, Humans, Immunology and Allergy, Pharmacology (medical), Immunosuppressive Agents
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d132fd1865271788d0942c0bcd481c02Test
https://doi.org/10.1111/ajt.17158Test -
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المصدر: European Journal of Cancer. 175:326-335
مصطلحات موضوعية: Graft Rejection, Cancer Research, Oncology, Neoplasms, TOR Serine-Threonine Kinases, Humans, MTOR Inhibitors, Immune Checkpoint Inhibitors, Immunosuppressive Agents, Transplant Recipients
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e000161ab5212e7067d5282e0682761Test
https://doi.org/10.1016/j.ejca.2022.08.010Test -
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المؤلفون: Sunbin Ling, Qifan Zhan, Guangjiang Jiang, Qiaonan Shan, Lu Yin, Rui Wang, Qingyang Que, Xuyong Wei, Shengjun Xu, Jiongjie Yu, Wei Zhou, Lincheng Zhang, Jiaqi Bao, Qianwei Ye, Renyi Su, Rongli Wei, Jimin Liu, Kangchen Chen, Jingrui Wang, Haiyang Xie, Shusen Zheng, Xin He, Jiajia Xiang, Xiao Xu
المصدر: American Journal of Transplantation. 22:2323-2336
مصطلحات موضوعية: Sirolimus, Transplantation, Carcinoma, Hepatocellular, TOR Serine-Threonine Kinases, Liver Neoplasms, MTOR Inhibitors, Hypoxia-Inducible Factor 1, alpha Subunit, Liver Transplantation, E2F7 Transcription Factor, Cell Line, Tumor, Humans, Immunology and Allergy, Pharmacology (medical), Hypoxia, Cell Proliferation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7920f40f5ddde1fe42d12ac309d1e63Test
https://doi.org/10.1111/ajt.17124Test -
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المؤلفون: Kevin Lou, Ziyang Zhang, Kevan M. Shokat, Xujun Luo, William A. Weiss, Qi-Wen Fan
المصدر: Nature, vol 609, iss 7928
مصطلحات موضوعية: Drug, General Science & Technology, media_common.quotation_subject, Central nervous system, Tacrolimus Binding Protein 1A, Pharmacology, Ligands, Rare Diseases, Drug Therapy, medicine, Humans, Adverse effect, PI3K/AKT/mTOR pathway, media_common, Cancer, Sirolimus, Multidisciplinary, Kinase, business.industry, TOR Serine-Threonine Kinases, Neurosciences, Brain, MTOR Inhibitors, Ligand (biochemistry), medicine.disease, Xenograft Model Antitumor Assays, Brain Disorders, Brain Cancer, medicine.anatomical_structure, FKBP, Orphan Drug, 5.1 Pharmaceuticals, Combination, Neurological, Drug Therapy, Combination, Development of treatments and therapeutic interventions, business, Glioblastoma
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d384cbe2d04023b9624254d84e3a1a69Test
https://doi.org/10.1038/s41586-022-05213-yTest -
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المؤلفون: Ina Aneva, Maciej Banach, Mohammad Amjad Kamal, Solomon Habtemariam, Maryam Khayatkashani, Adeleh Sahebnasagh, Parames C. Sil, Kasturi Sarkar, Hamid Reza Khayat Kashani
المصدر: Combinatorial Chemistry & High Throughput Screening. 25:1805-1808
مصطلحات موضوعية: Mechanistic Target of Rapamycin Complex 2, mTORC1, Mechanistic Target of Rapamycin Complex 1, mTORC2, Tacrolimus, Influenza A Virus, H1N1 Subtype, Drug Discovery, Humans, Medicine, Everolimus, PI3K/AKT/mTOR pathway, Sirolimus, SARS-CoV-2, business.industry, Cell growth, TOR Serine-Threonine Kinases, Organic Chemistry, MTOR Inhibitors, General Medicine, Temsirolimus, COVID-19 Drug Treatment, Computer Science Applications, Multiprotein Complexes, Cancer research, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72199e9674c30fb8803450798d43213Test
https://doi.org/10.2174/1386207325666211130140923Test -
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المؤلفون: Jan Miroslav Hartinger, Pavel Ryšánek, Ondřej Slanař, Martin Šíma
المصدر: Journal of Clinical Pharmacy and Therapeutics. 47:1362-1367
مصطلحات موضوعية: Sirolimus, Pharmacology, TOR Serine-Threonine Kinases, Humans, Pharmacology (medical), MTOR Inhibitors, Organ Transplantation, Immunosuppressive Agents
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df3c06328802dcb0221dd956307feb5Test
https://doi.org/10.1111/jcpt.13753Test -
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المؤلفون: Wenda Wang, Zhan Wang, Yang Zhao, Xu Wang, Hanzhong Li, Yushi Zhang
المصدر: Journal of Clinical Pharmacy and Therapeutics. 47:979-985
مصطلحات موضوعية: Sirolimus, Pharmacology, TOR Serine-Threonine Kinases, Cholesterol, HDL, Hyperlipidemias, Cholesterol, LDL, MTOR Inhibitors, Carotenoids, Lipids, Leukemia, Myeloid, Acute, Tuberous Sclerosis, Humans, Pharmacology (medical), Vitamin A, Triglycerides, Apolipoproteins B, Retrospective Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f771f6c8dc3997b75c337f2703e8813fTest
https://doi.org/10.1111/jcpt.13631Test -
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المؤلفون: Xiao-Lian, Liu, Gui-Ming, Zhang, Si-Si, Huang, Wen-Hui, Shi, Lin-Xuan, Ye, Zhong-Lu, Ren, Jia-Jie, Zhang, Shu-Wen, Liu, Le, Yu, Yi-Lei, Li
المصدر: Acta Pharmacologica Sinica. 43:2397-2409
مصطلحات موضوعية: Pharmacology, TOR Serine-Threonine Kinases, Tumor Suppressor Proteins, PTEN Phosphohydrolase, MTOR Inhibitors, General Medicine, Zebrafish Proteins, Kidney Neoplasms, Mice, Mutation, Animals, Humans, Pharmacology (medical), Carcinoma, Renal Cell, Zebrafish
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c9126aa0d5816a7761cf6226602aa3Test
https://doi.org/10.1038/s41401-022-00862-1Test