نتائج البحث - "Patrizia Agostinis"

1

Kinase Photoaffinity Labeling Reveals Low Selectivity Profile of the IRE1 Targeting Imidazopyrazine-Based KIRA6 Inhibitor

المؤلفون: Rita Derua, Dimitris Korovesis, Nicole Rufo, Steven H. L. Verhelst, Patrizia Agostinis

المصدر: ACS Chemical Biology. 15:3106-3111

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55afe163bdb72b4d19cc9761fd91d285Test
https://doi.org/10.1021/acschembio.0c00802Test

2

Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1 alpha kinase inhibitor KIRA6 through HSP60 targeting

المؤلفون: Sofie Van Eygen, Rita Derua, Dimitris Korovesis, Thomas Sauter, Monica Vara-Perez, Leonidas G. Alexopoulos, Lasse Sinkkonen, Francesca Finotello, Nicole Rufo, Jan Rožanc, Michael Dewaele, Patrizia Agostinis, Abhishek D. Garg, Sophie Janssens, Peter de Witte, Steven H. L. Verhelst

المصدر: Cell Death and Differentiation
CELL DEATH AND DIFFERENTIATION

مصطلحات موضوعية: RECRUITMENT, Chemokine, RNA-SEQ EXPERIMENTS, Inflammation, Immunogenic Cell Death, Signal transduction, Naphthalenes, Protein Serine-Threonine Kinases, Endoplasmic Reticulum, ER-STRESS, Article, Proinflammatory cytokine, ACTIVATION, Target identification, Chaperones, Endoribonucleases, Medicine and Health Sciences, Medicine, Humans, Molecular Biology, CALRETICULIN EXPOSURE, biology, business.industry, UNFOLDED-PROTEIN-RESPONSE, Immune cell death, Imidazoles, Biology and Life Sciences, Cell Biology, Dendritic cell, CANCER, APOPTOSIS, DIFFERENTIAL EXPRESSION ANALYSIS, Pyrazines, Cancer cell, Cancer research, biology.protein, Unfolded protein response, Immunogenic cell death, medicine.symptom, Chemokines, business

وصف الملف: Print-Electronic; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e250130d194566c9e02cd034ace4c3c5Test
https://lirias.kuleuven.be/handle/123456789/679916Test

3

BNIP3 promotes HIF‐1α‐driven melanoma growth by curbing intracellular iron homeostasis

المصدر: The EMBO Journal

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, HIF‐, 1α, Apoptosis, Inbred C57BL, Mice, 0302 clinical medicine, Mitophagy, Cancer, 0303 health sciences, Tumor, HIF‐1α, General Neuroscience, Melanoma, Articles, Immunohistochemistry, 3. Good health, Autophagy & Cell Death, Female, Hypoxia-Inducible Factor 1, Life Sciences & Biomedicine, Intracellular, Signal Transduction, Biochemistry & Molecular Biology, BNIP3, Immunoblotting, ATG5, HIF-1α, Biology, alpha Subunit, Article, Gas Chromatography-Mass Spectrometry, General Biochemistry, Genetics and Molecular Biology, Cell Line, Mitochondrial Proteins, 03 medical and health sciences, Downregulation and upregulation, In vivo, Cell Line, Tumor, melanoma, medicine, Animals, Humans, Gene silencing, Molecular Biology, 030304 developmental biology, ferritinophagy, metabolism, Computational Biology, Hypoxia-Inducible Factor 1, alpha Subunit, Membrane Proteins, Mice, Inbred C57BL, Science & Technology, General Immunology and Microbiology, Cell Biology, medicine.disease, Cancer research, 030217 neurology & neurosurgery

وصف الملف: Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8105460bf5b75f4db7cdc6ad825546Test
https://doi.org/10.15252/embj.2020106214Test

4

Endothelial cell autophagy in homeostasis and cancer

المؤلفون: Patrizia Agostinis, Jelle Verhoeven, Madhur Agrawal, Jef Baelen

مصطلحات موضوعية: Endothelial cells, Biophysics, Autophagy-Related Proteins, Biology, Biochemistry, 03 medical and health sciences, Immune system, Structural Biology, Tumor vasculature, Neoplasms, Genetics, medicine, Tumor Microenvironment, Autophagy, Animals, Homeostasis, Humans, Hypoxia, Molecular Biology, Immunologic Surveillance, 030304 developmental biology, Cancer, 0303 health sciences, Neovascularization, Pathologic, Mechanism (biology), 030302 biochemistry & molecular biology, Immunosurveillance, Endothelial Cells, Cell Biology, Hypoxia (medical), Cell biology, Endothelial stem cell, Gene Expression Regulation, Neoplastic, Metabolic pathway, Blood Vessels, Cytokines, medicine.symptom, Lysosomes, Signal Transduction

وصف الملف: Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ffb04bba95e07565416c320765ea54Test
https://lirias.kuleuven.be/handle/123456789/674122Test

5

Autophagy in endothelial cells and tumor angiogenesis

المؤلفون: Diede Houbaert, Marco B.E. Schaaf, Odeta Mece, Patrizia Agostinis

المصدر: Cell Death and Differentiation

وصف الملف: Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deda9c5c3a6c8ff8ba81a699edb4c43cTest
https://doi.org/10.1038/s41418-019-0287-8Test

6

Lipid availability determines fate of skeletal progenitor cells via SOX9

المساهمون: CBITE, RS: MERLN - Cell Biology - Inspired Tissue Engineering (CBITE)

المصدر: Nature, 579(7797), 111-117. Nature Publishing Group

وصف الملف: application/pdf; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc0f87d3f5257cfa5eb404e4fe511aaTest
https://doi.org/10.1530/ey.17.5.12Test

7

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy

المؤلفون: Sarah-Maria Fendt, Francesca Maria Bosisio, Aljosja Rogiers, Florian Rambow, Rita Derua, Kathleen Van den Eynde, David Nittner, Ali Talebi, Etienne Waelkens, Joost van den Oord, Joao A.G. Duarte, Kris Nys, Jonas Dehairs, Jean-Christophe Marine, Frank Vanderhoydonc, Monica Vara Perez, Patrizia Agostinis, Johannes V. Swinnen

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Pyridines, medicine.medical_treatment, Regulator, General Physics and Astronomy, Mice, SCID, Targeted therapy, Gene Knockout Techniques, Mice, lcsh:Science, Vemurafenib, Melanoma, Multidisciplinary, Chemistry, Gene Expression Regulation, Neoplastic, Lipogenesis, Melanocytes, Female, lipids (amino acids, peptides, and proteins), Sterol Regulatory Element Binding Protein 1, Signal Transduction, medicine.drug, Proto-Oncogene Proteins B-raf, Science, Down-Regulation, Mice, Nude, Antineoplastic Agents, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, Protein Kinase Inhibitors, neoplasms, General Chemistry, medicine.disease, Xenograft Model Antitumor Assays, Sterol regulatory element-binding protein, Thiazoles, 030104 developmental biology, Drug Resistance, Neoplasm, Mutation, Cancer research, lcsh:Q

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132605deb2b464bc9143e438d21eb553Test
https://doaj.org/article/c1bb7bfd70be4f42827f1d7f1e16991fTest

8

The Unfolded Protein Response in Immunogenic Cell Death and Cancer Immunotherapy

المؤلفون: Abhishek D. Garg, Nicole Rufo, Patrizia Agostinis

المصدر: Trends in Cancer

وصف الملف: Print-Electronic; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a0d5701bfd6a2ab161d74dbbf2a35aTest
https://doi.org/10.1016/j.trecan.2017.07.002Test

9

Pathogen response-like recruitment and activation of neutrophils by sterile immunogenic dying cells drives neutrophil-mediated residual cell killing

المؤلفون: Sofie Van Eygen, Matthias Van Woensel, Norbert Graf, Stefaan Van Gool, Tekele Fasche, Abhishek D. Garg, Carolien Koks, Jan Willem Maes, Peter de Witte, Patrizia Agostinis, Petri Salven, Shentong Fang, Niels Vanthillo, Lien Vandenberk

المصدر: Cell Death & Differentiation. 24:832-843

مصطلحات موضوعية: Cytotoxicity, Immunologic, Male, 0301 basic medicine, Chemokine, Neutrophils, Chemokine CXCL1, Apoptosis, Inflammation, Animals, Genetically Modified, Mice, 03 medical and health sciences, Immunity, Cell Line, Tumor, medicine, Animals, Humans, Cytotoxic T cell, CXCL10, Molecular Biology, Chemokine CCL2, Zebrafish, Original Paper, Innate immune system, biology, Epithelial Cells, Cell Biology, Coculture Techniques, Cell biology, Chemokine CXCL10, Mice, Inbred C57BL, 030104 developmental biology, Cell killing, Gene Expression Regulation, Toll-Like Receptor 7, Chemokines, CC, Myeloid Differentiation Factor 88, Cancer cell, biology.protein, Melanocytes, Female, medicine.symptom, Neuroglia, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8b692cbf6b62490b482dbbd978aa6bTest
https://doi.org/10.1038/cdd.2017.15Test

10

NF-κB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis

المؤلفون: Behnaz Ahangarian Abhari, Nicole McCarthy, Patrizia Agostinis, Simone Fulda

المصدر: Apoptosis

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Programmed cell death, Clinical Biochemistry, Pharmaceutical Science, Apoptosis, Inhibitor of apoptosis, Cell Line, Inhibitor of Apoptosis Proteins, Mitochondrial Proteins, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, NF-KappaB Inhibitor alpha, Humans, Pharmacology, Gene knockdown, Chemistry, Kinase, Tunicamycin, Biochemistry (medical), Intracellular Signaling Peptides and Proteins, NF-kappa B, NF-κB, Cell Biology, 3. Good health, Cell biology, Up-Regulation, IκBα, 030104 developmental biology, HEK293 Cells, 030220 oncology & carcinogenesis, Myeloid Cell Leukemia Sequence 1 Protein, Apoptosis Regulatory Proteins, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1594c2544a6a92e11af7e08e00c097e6Test
https://pubmed.ncbi.nlm.nih.gov/30680482Test

تنقيح النتائج