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المؤلفون: Xiaobin Xu, Aming Zhang, Yingjie Xu, Yuan Cao, Stephen Cale, Matthew Franklin, Prasad Sarangapani, Peter M. Ihnat, Haibo Qiu, Dingjiang Liu, Erica A. Pyles, Mohammed Shameem, Ning Li
المصدر: Journal of Pharmaceutical Sciences. 111:1335-1345
مصطلحات موضوعية: Viscosity, Microdialysis, Antibodies, Monoclonal, Deuterium Exchange Measurement, Humans, Pharmaceutical Science, Hydrogen Deuterium Exchange-Mass Spectrometry, Deuterium, Complementarity Determining Regions, Mass Spectrometry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5df5011bc0d9950e5e4b7d3f135ef7Test
https://doi.org/10.1016/j.xphs.2021.12.027Test -
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المؤلفون: Michelle Tran, Rachel L. Signorelli, Adriana Yamaguchi, Eefie Chen, Michael Holinstat, Anthony T. Iavarone, Adam R. Offenbacher, Theodore Holman
مصطلحات موضوعية: Blood Platelets, Biochemistry & Molecular Biology, Biophysics, Deuterium Exchange Measurement, Single Nucleotide, Hematology, Deuterium, Arachidonate 12-Lipoxygenase, Biochemistry, Liposomes, Humans, 2.1 Biological and endogenous factors, Biochemistry and Cell Biology, Polymorphism, Aetiology, Molecular Biology, Hydrogen
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f9a998da61ed346989afd2958a0730Test
https://escholarship.org/uc/item/60g5005rTest -
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المؤلفون: Seetaloo, Neeleema, Zacharopoulou, Maria, Stephens, Amberley D, Kaminski Schierle, Gabriele S, Phillips, Jonathan J
المساهمون: Seetaloo, Neeleema [0000-0002-8312-2542], Stephens, Amberley D [0000-0002-7303-6392], Kaminski Schierle, Gabriele S [0000-0002-1843-2202], Phillips, Jonathan J [0000-0002-5361-9582], Apollo - University of Cambridge Repository
المصدر: Analytical chemistry. 94(48)
مصطلحات موضوعية: Protein Conformation, alpha-Synuclein, Humans, Deuterium Exchange Measurement, Hydrogen Deuterium Exchange-Mass Spectrometry, Parkinson Disease, Deuterium, Article, Analytical Chemistry
وصف الملف: application/pdf; application/zip; text/xml
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44e097d2e596cccd57f23e1a1016fb8Test
https://pubmed.ncbi.nlm.nih.gov/36413494Test -
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المؤلفون: Zheng Jian Li, Guodong Chen, Li Tao
المصدر: Drug Discovery Today. 27:196-206
مصطلحات موضوعية: Pharmacology, Protein therapeutics, Protein Conformation, Chemistry, Drug Compounding, Deuterium Exchange Measurement, Proteins, Computational biology, Photochemical Processes, Mass spectrometry, Mass Spectrometry, Stability assessment, Characterization (materials science), Structure-Activity Relationship, Epitope mapping, Drug Development, Drug Discovery, Humans, Hydrogen–deuterium exchange, Higher Order Structure
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae999ccb9e706280083492927b01199Test
https://doi.org/10.1016/j.drudis.2021.09.010Test -
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المؤلفون: Neel H. Shah, Christine L. Gee, John Kuriyan, Jean M. Badroos, Helen T. Hobbs, Susan Marqusee
المصدر: Protein Science : A Publication of the Protein Society
مصطلحات موضوعية: Protein Conformation, alpha-Helical, Conformational change, Full‐Length Papers, T-Lymphocytes, Genetic Vectors, Gene Expression, Syk, chemical and pharmacologic phenomena, Adaptive Immunity, Molecular Dynamics Simulation, Crystallography, X-Ray, SH2 domain, Biochemistry, Full‐Length Paper, evolution, Immunoreceptor tyrosine-based activation motif, Escherichia coli, Animals, Humans, Syk Kinase, Protein Interaction Domains and Motifs, Cloning, Molecular, Tyrosine, Molecular Biology, B-Lymphocytes, Binding Sites, ZAP-70 Protein-Tyrosine Kinase, Chemistry, conformational landscape, hydrogen–deuterium exchange mass spectrometry, tyrosine kinase signaling, Deuterium Exchange Measurement, hemic and immune systems, Biological Evolution, Recombinant Proteins, Protein kinase domain, protein dynamics, Biophysics, Phosphorylation, Protein Conformation, beta-Strand, Tyrosine kinase, Protein Binding, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838256900e2374647a4621bc4fc68d20Test
https://doi.org/10.1002/pro.4199Test -
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المؤلفون: Jodi Shaulsky, Andrew C. Good, Roman V. Agafonov, Tobie D. Lee, Christopher G. Nasveschuk, Andrew J. K. Phillips, Joe Sahil Patel, Ryan E. Michael, Hongwei Huang, Scott J. Eron, Mark E. Fitzgerald, Stewart L. Fisher, Ashley A. Hart
المصدر: 'ACS Chemical Biology ', vol: 16, pages: 2228-2243 (2021)
مصطلحات موضوعية: Models, Molecular, Indoles, Protein Conformation, Cell Cycle Proteins, Protein degradation, Biochemistry, Mass Spectrometry, Piperidines, Acetamides, Humans, Molecule, Computer Simulation, Macromolecular docking, Ternary complex, Molecular Structure, Chemistry, Deuterium Exchange Measurement, General Medicine, Combinatorial chemistry, HEK293 Cells, Gene Expression Regulation, Models, Chemical, Docking (molecular), Molecular Medicine, Hydrogen–deuterium exchange, Ternary operation, Linker, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cbcbb46e22a554e95dd60b690230ecTest
https://doi.org/10.1021/acschembio.1c00376Test -
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المصدر: ACS Chem Neurosci
مصطلحات موضوعية: Gene isoform, Physiology, Cognitive Neuroscience, Kinetics, Mutant, Peptide, Biochemistry, Article, 03 medical and health sciences, Residue (chemistry), 0302 clinical medicine, Alzheimer Disease, Amyloid precursor protein, Humans, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Amyloid beta-Peptides, biology, Deuterium Exchange Measurement, Cell Biology, General Medicine, Deuterium, Peptide Fragments, In vitro, chemistry, Biophysics, biology.protein, Hydrogen–deuterium exchange, 030217 neurology & neurosurgery, Hydrogen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b75628e276ac4f16ab8c107ac0905a3Test
https://doi.org/10.1021/acschemneuro.1c00072Test -
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المؤلفون: Marius Gramlich, Sandra Maier, Philipp D. Kaiser, Bjoern Traenkle, Teresa R. Wagner, Josef Voglmeir, Dieter Stoll, Ulrich Rothbauer, Anne Zeck
المصدر: Analytical chemistry. 94(27)
مصطلحات موضوعية: Tandem Mass Spectrometry, Deuterium Exchange Measurement, Humans, Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase, Deuterium, Epitope Mapping, Analytical Chemistry, Hydrogen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e87723e30672a2ddcb3ec592c7db0eTest
https://pubmed.ncbi.nlm.nih.gov/35749695Test -
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المؤلفون: Julie Ducharme, Vanja Polic, Christopher J. Thibodeaux, Karine Auclair
المصدر: ACS Chemical Biology. 16:882-890
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Allosteric regulation, Hydrogen Deuterium Exchange-Mass Spectrometry, Plasma protein binding, Molecular Dynamics Simulation, Ligands, 01 natural sciences, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, Protein structure, Cytochrome P-450 CYP3A, Humans, Structure–activity relationship, Bioconjugation, 010405 organic chemistry, Ligand, Chemistry, Deuterium Exchange Measurement, General Medicine, Deuterium, Small molecule, 0104 chemical sciences, 3. Good health, 030104 developmental biology, Biophysics, Molecular Medicine, Hydrogen–deuterium exchange, Allosteric Site, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0676cc08793fae1577d21f2c72cee82Test
https://doi.org/10.1021/acschembio.1c00084Test -
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المؤلفون: Miklos Guttman, Rick Harkewicz, Kimberly M. Alonge
المصدر: Curr Mol Med
مصطلحات موضوعية: Spectrometry, Mass, Electrospray Ionization, Ion-mobility spectrometry, Chondroitin Sulfates, Disaccharide, Deuterium Exchange Measurement, General Medicine, Mass spectrometry, Biochemistry, Article, chemistry.chemical_compound, Sulfation, chemistry, Deuterium, Computational chemistry, Humans, Molecular Medicine, Hydrogen–deuterium exchange, Chondroitin sulfate, Sulfate, Molecular Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e46484e92eefadf3dfb7957fc278ddTest
https://doi.org/10.2174/1566524020666200915110707Test
