المؤلفون: Anders Bergström, David W. G. Stanton, Ulrike H. Taron, Laurent Frantz, Mikkel-Holger S. Sinding, Erik Ersmark, Saskia Pfrengle, Molly Cassatt-Johnstone, Ophélie Lebrasseur, Linus Girdland-Flink, Daniel M. Fernandes, Morgane Ollivier, Leo Speidel, Shyam Gopalakrishnan, Michael V. Westbury, Jazmin Ramos-Madrigal, Tatiana R. Feuerborn, Ella Reiter, Joscha Gretzinger, Susanne C. Münzel, Pooja Swali, Nicholas J. Conard, Christian Carøe, James Haile, Anna Linderholm, Semyon Androsov, Ian Barnes, Chris Baumann, Norbert Benecke, Hervé Bocherens, Selina Brace, Ruth F. Carden, Dorothée G. Drucker, Sergey Fedorov, Mihály Gasparik, Mietje Germonpré, Semyon Grigoriev, Pam Groves, Stefan T. Hertwig, Varvara V. Ivanova, Luc Janssens, Richard P. Jennings, Aleksei K. Kasparov, Irina V. Kirillova, Islam Kurmaniyazov, Yaroslav V. Kuzmin, Pavel A. Kosintsev, Martina Lázničková-Galetová, Charlotte Leduc, Pavel Nikolskiy, Marc Nussbaumer, Cóilín O’Drisceoil, Ludovic Orlando, Alan Outram, Elena Y. Pavlova, Angela R. Perri, Małgorzata Pilot, Vladimir V. Pitulko, Valerii V. Plotnikov, Albert V. Protopopov, André Rehazek, Mikhail Sablin, Andaine Seguin-Orlando, Jan Storå, Christian Verjux, Victor F. Zaibert, Grant Zazula, Philippe Crombé, Anders J. Hansen, Eske Willerslev, Jennifer A. Leonard, Anders Götherström, Ron Pinhasi, Verena J. Schuenemann, Michael Hofreiter, M. Thomas P. Gilbert, Beth Shapiro, Greger Larson, Johannes Krause, Love Dalén, Pontus Skoglund

المساهمون: Bergström, Anders [0000-0002-4096-9268], Frantz, Laurent [0000-0001-8030-3885], Sinding, Mikkel-Holger S [0000-0003-1371-219X], Lebrasseur, Ophélie [0000-0003-0687-8538], Fernandes, Daniel M [0000-0002-7434-6552], Ollivier, Morgane [0000-0002-8361-4221], Westbury, Michael V [0000-0003-0478-3930], Ramos-Madrigal, Jazmin [0000-0002-1661-7991], Feuerborn, Tatiana R [0000-0003-1610-3402], Conard, Nicholas J [0000-0002-4633-0385], Haile, James [0000-0002-8521-8337], Linderholm, Anna [0000-0002-1613-9926], Barnes, Ian [0000-0001-8322-6918], Baumann, Chris [0000-0002-1001-8621], Bocherens, Hervé [0000-0002-0494-0126], Brace, Selina [0000-0003-2126-6732], Drucker, Dorothée G [0000-0003-0854-4371], Germonpré, Mietje [0000-0001-8865-0937], Jennings, Richard P [0000-0001-9996-7518], Kuzmin, Yaroslav V [0000-0002-4512-2269], Orlando, Ludovic [0000-0003-3936-1850], Outram, Alan [0000-0003-3360-089X], Perri, Angela R [0000-0002-4349-1060], Plotnikov, Valerii V [0000-0002-4870-3499], Sablin, Mikhail [0000-0002-2773-7454], Crombé, Philippe [0000-0002-4198-8057], Hansen, Anders J [0000-0002-1890-2702], Willerslev, Eske [0000-0002-7081-6748], Leonard, Jennifer A [0000-0003-0291-7819], Pinhasi, Ron [0000-0003-1629-8131], Shapiro, Beth [0000-0002-2733-7776], Larson, Greger [0000-0002-4092-0392], Krause, Johannes [0000-0001-9144-3920], Dalén, Love [0000-0001-8270-7613], Skoglund, Pontus [0000-0002-3021-5913], Apollo - University of Cambridge Repository, The Francis Crick Institute [London], Swedish Museum of Natural History (NRM), Ludwig Maximilian University [Munich] (LMU), University of Copenhagen = Københavns Universitet (UCPH), Trinity College Dublin, University of Greenland, University of Tübingen, University of Oxford, Ecosystèmes, biodiversité, évolution [Rennes] (ECOBIO), Université de Rennes (UR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS), University College of London [London] (UCL), IT University of Copenhagen (ITU), Max Planck Institute for the Science of Human History (MPI-SHH), Max-Planck-Gesellschaft, Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen, Globe Institute, Faculty of Health and Medical Sciences, University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Texas A&M University System, Stockholm University, Natural History Museum [Oslo], University of Oslo (UiO), German Archaeological Institute (DAI), The Natural History Museum [London] (NHM), UCD School of Biology and Environmental Science, UCD, Royal Belgian Institute of Natural Sciences (RBINS), North-Eastern Federal University, School of Archaeology, Histoire naturelle de l'Homme préhistorique (HNHP), Muséum national d'Histoire naturelle (MNHN)-Université de Perpignan Via Domitia (UPVD)-Centre National de la Recherche Scientifique (CNRS), Centre d'anthropologie et de génomique de Toulouse (CAGT), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), University of Vienna [Vienna], Max Planck Institute for Evolutionary Anthropology [Leipzig], This work was supported by grants to P. Skoglund from the European Research Council (grant no. 852558), the Erik Philip Sörensen Foundation and the Science for Life Laboratory, Swedish Biodiversity Program, made available by support from the Knut and Alice Wallenberg Foundation. A.B., L.S., P. Swali and P. Skoglund were supported by Francis Crick Institute core funding (FC001595) from Cancer Research UK, the UK Medical Research Council and the Wellcome Trust. P. Skoglund was also supported by the Vallee Foundation, the European Molecular Biology Organisation and the Wellcome Trust (217223/Z/19/Z). Computations were supported by SNIC-UPPMAX. We also acknowledge support from Science for Life Laboratory, the Knut and Alice Wallenberg Foundation, the National Genomics Infrastructure funded by the Swedish Research Council and the Uppsala Multidisciplinary Center for Advanced Computational Science for assistance with massively parallel sequencing and access to the UPPMAX computational infrastructure. We thank the Yukon gold mining community and First Nations, including the Tr’ondëk Hwëch’in, for continued support of our palaeontology research in the Yukon Territories, Canada. We thank the Danish National High-Throughput Sequencing Centre and BGI-Europe for assistance in sequencing data generation and the Danish National Supercomputer for Life Sciences–Computerome (https://computerome.dtu.dkTest) for computational resources. We thank National Museum Wales for continued sampling support. M. Germonpré acknowledges support from the Brain.be 2.0 ICHIE project (BELSPO B2/191/P2/ICHIE). M.T.P.G. was supported by the European Research Council (grant no. 681396). M.-H.S.S. was supported by the Velux Foundations through the Qimmeq Project, the Aage og Johanne Louis-Hansens Fond and the Independent Research Fund Denmark (8028-00005B). L.D. acknowledges support from FORMAS (2018-01640). D.W.G.S. received funding for this project from the European Union’s Horizon 2020 research and innovation programme under Marie Skłodowska-Curie grant agreement no. 796877. M.P. was supported by the Polish National Agency for Academic Exchange–NAWA (grant no. PPN/PPO/2018/1/00037). V.J.S. was supported by the University of Zurich’s University Research Priority Program ‘Evolution in Action: From Genomes to Ecosystems’. This research was done with the participation of ZIN RAS (grant no. 075-15-2021-1069). We are grateful to the museum of the Institute of Plant and Animal Ecology UB RAS (Ekaterinburg, Russia) for provision of samples. R.P.J. and C.O’D. were supported by the Standing Committee for Archaeology of the Royal Irish Academy through the Archaeological Excavation Research Grant Scheme. E.Y.P., P.N. and V.V.P. are supported by the Russian Science Foundation (grant no. 16-18-10265-RNF and 21-18-00457-RNF). Y.V.K. was supported by the Russian Science Foundation (grant no. 20-17-00033). M.H. was supported by the European Research Council (consolidator grant GeneFlow no. 310763). M.L.-G. was supported by the Czech Science Foundation GAČR (grant no. 15-06446S) and institutional financing of the Moravian Museum from the Czech Ministry of Culture (IP DKRVO 2019-2023, MK000094862). L.S. is supported by the Sir Henry Wellcome fellowship (220457/Z/20/Z). We thank Staatliches Museum für Naturkunde Stuttgart for sample access. L.F. and G.L. were supported by European Research Council grants (ERC-2013-StG-337574-UNDEAD and ERC-2019-StG-853272-PALAEOFARM) and Natural Environmental Research Council grants (NE/K005243/1, NE/K003259/1, NE/S007067/1 and NE/S00078X/1). L.F. was also supported by the Wellcome Trust (210119/Z/18/Z). This research was funded in whole, or in part, by the Wellcome Trust (FC001595). For the purpose of open access, the author has applied a CC-BY public copyright licence to any author accepted manuscript version arising from this submission., Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut Ecologie et Environnement (INEE), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS), Department of Geosciences and Geography, Faculty of Science

المصدر: Bergström, Anders; Stanton, David W G; Taron, Ulrike H; Frantz, Laurent; Sinding, Mikkel-Holger S; Ersmark, Erik; Pfrengle, Saskia; Cassatt-Johnstone, Molly; Lebrasseur, Ophélie; Girdland-Flink, Linus; Fernandes, Daniel M; Ollivier, Morgane; Speidel, Leo; Gopalakrishnan, Shyam; Westbury, Michael V; Ramos-Madrigal, Jazmin; Feuerborn, Tatiana R; Reiter, Ella; Gretzinger, Joscha; Münzel, Susanne C; ... (2022). Grey wolf genomic history reveals a dual ancestry of dogs. Nature, 607(7918), pp. 313-320. Springer Nature 10.1038/s41586-022-04824-9 <http://dx.doi.org/10.1038/s41586-022-04824-9Test>
Nature
Bergström, A, Stanton, D W G, Taron, U H, Frantz, L, Sinding, M H S, Ersmark, E, Pfrengle, S, Cassatt-Johnstone, M, Lebrasseur, O, Girdland-Flink, L, Fernandes, D M, Ollivier, M, Speidel, L, Gopalakrishnan, S, Westbury, M V, Ramos-Madrigal, J, Feuerborn, T R, Reiter, E, Gretzinger, J, Münzel, S C, Swali, P, Conard, N J, Carøe, C, Haile, J, Linderholm, A, Androsov, S, Barnes, I, Baumann, C, Benecke, N, Bocherens, H, Brace, S, Carden, R F, Drucker, D G, Fedorov, S, Gasparik, M, Germonpré, M, Grigoriev, S, Groves, P, Hertwig, S T, Ivanova, V V, Janssens, L, Jennings, R P, Kasparov, A K, Kirillova, I V, Kurmaniyazov, I, Kuzmin, Y V, Kosintsev, P A, Lázničková-Galetová, M, Leduc, C, Nikolskiy, P, Nussbaumer, M, O’Drisceoil, C, Orlando, L, Outram, A, Pavlova, E Y, Perri, A R, Pilot, M, Pitulko, V V, Plotnikov, V V, Protopopov, A V, Rehazek, A, Sablin, M, Seguin-Orlando, A, Storå, J, Verjux, C, Zaibert, V F, Zazula, G, Crombé, P, Hansen, A J, Willerslev, E, Leonard, J A, Götherström, A, Pinhasi, R, Schuenemann, V J, Hofreiter, M, Gilbert, M T P, Shapiro, B, Larson, G, Krause, J, Dalén, L & Skoglund, P 2022, ' Grey wolf genomic history reveals a dual ancestry of dogs ', Nature, vol. 607, no. 7918, pp. 313-320 . https://doi.org/10.1038/s41586-022-04824-9Test
Nature, 2022, ⟨10.1038/s41586-022-04824-9⟩
Nature, Nature Publishing Group, 2022, ⟨10.1038/s41586-022-04824-9⟩
NATURE
Nature, vol 607, iss 7918

مصطلحات موضوعية: History, RUSSIAN FEDERATION, 631/158/2464, CANIS LUPUS, ANIMAL EXPERIMENT, Domestication, Ecology,Evolution & Ethology, MIDDLE EAST, DOG, History, Ancient, Phylogeny, CANID, WOLF, Multidisciplinary, Genome, ORIGIN, article, 45/77, Genomics, CC, ADMIXTURE, CONTAMINATION, Europe, GENOME, EXTINCTION, DOGS, COMPLETE MITOCHONDRIAL GENOME, Genetics & Genomics, NATURAL SELECTION, 1171 Geosciences, AFRICA, EUROPE, NORTH AMERICA, GENETICS, SIBERIA, General Science & Technology, PHYLOGENY, PLEISTOCENE, LIBRARY PREPARATION, 45/23, Infectious Disease, ANCESTRY, SEQUENCE, EURASIA, Ancient, TIME SERIES ANALYSIS, 631/181/27, Middle East, QH301, Dogs, UPPER PLEISTOCENE, Genetic, EVOLUTIONARY HISTORY, WOLVES, GENE MUTATION, ANCIENT DNA, Animals, NONHUMAN, 631/181/457, DNA, Ancient, Selection, Genetic, ARTICLE, Selection, QH426, QL, Wolves, History and Archaeology, Tumor Suppressor Proteins, ANIMALS, Biology and Life Sciences, DNA, ANIMAL, GENE, Siberia, CONTROLLED STUDY, DOMESTICATION, 631/181/2474, Africa, Mutation, North America, 570 Life sciences, biology, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, GENOMICS

وصف الملف: application/pdf; application/zip; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c464467823beb42b77db28634ed4c98Test
https://boris.unibe.ch/171035/1/s41586-022-04824-9.pdfTest

المؤلفون: Alexei Protopopov, Xingzhi Song, Jiabin Tang, Lynda Chin, Christopher A. Bristow, Lixing Yang, Xiaojia Ren, Lovelace J. Luquette, Yiqun Zhang, Jonathan G. Seidman, Chad J. Creighton, Melanie H. Kucherlapati, Raju Kucherlapati, Eunjung Lee, Semin Lee, Huandong Sun, Ruibin Xi, Harshad S. Mahadeshwar, Jianhua Zhang, Angela Hadjipanayis, Angeliki Pantazi, Sahil Seth, Peter J. Park

المصدر: Genome Biology, Vol 20, Iss 1, Pp 1-24 (2019)
Genome Biology

مصطلحات موضوعية: Methyltransferase, lcsh:QH426-470, Genomic Structural Variation, Structural variation, Epigenome, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Humans, Gene, lcsh:QH301-705.5, 030304 developmental biology, Genetics, 0303 health sciences, biology, Research, Methylation, lcsh:Genetics, Histone, CpG site, lcsh:Biology (General), 030220 oncology & carcinogenesis, DNA methylation, biology.protein, CpG Islands

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c192ce8a0a6d482f055c2ad6d2e848eTest
http://link.springer.com/article/10.1186/s13059-019-1818-9Test

المؤلفون: Semin Lee, Huandong Sun, Lovelace J. Luquette, Chad J. Creighton, Melanie H. Kucherlapati, Yiqun Zhang, Xiaojia Ren, Raju Kucherlapati, Lynda Chin, Alexei Protopopov, Lixing Yang, Xingzhi Song, Fengju Chen, Christopher A. Bristow, Jiabin Tang, Jonathan G. Seidman, Jianhua Zhang, Wei Li, Eunjung Lee, Angela Hadjipanayis, Angeliki Pantazi, Sahil Seth, Peter J. Park, Harshad S. Mahadeshwar, Ruibin Xi

المصدر: Cell Reports, Vol 24, Iss 2, Pp 515-527 (2018)

مصطلحات موضوعية: 0301 basic medicine, DNA Copy Number Variations, Carcinogenesis, Article, General Biochemistry, Genetics and Molecular Biology, Structural variation, 03 medical and health sciences, Neoplasms, Humans, PTEN, Enhancer, lcsh:QH301-705.5, Gene, Exome sequencing, Gene Rearrangement, Whole genome sequencing, Genetics, Base Sequence, biology, Genome, Human, Point mutation, Breakpoint, Gene Expression Regulation, Neoplastic, Enhancer Elements, Genetic, 030104 developmental biology, lcsh:Biology (General), biology.protein, Genes, Neoplasm

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ed596b31d7906a2224e2a9e5ea2de2Test
https://doi.org/10.1016/j.celrep.2018.06.025Test

المؤلفون: Joachim Theilhaber, Jack Pollard, Alexei Protopopov, Maximilian Rogers-Grazado

المصدر: Cancer Research. 80:4276-4276

مصطلحات موضوعية: Cancer Research, Colorectal cancer, RNA, Computational biology, Biology, medicine.disease, Target enrichment, Gene expression profiling, Oncology, Gene expression, medicine, Nucleic acid, RNA extraction, Gene

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::37951abd7fb08d44452aa6d183a29429Test
https://doi.org/10.1158/1538-7445.am2020-4276Test

المؤلفون: Ni Zhao, Carter Van Waes, Lori Boice, Ashley H. Salazar, Petar Stojanov, Michael B. Prystowsky, Akinyemi I. Ojesina, Tara M. Lichtenberg, Nikolaus Schultz, Joshua M. Stuart, Mitchell J. Frederick, Julie M. Gastier-Foster, Jeffrey N. Myers, Bradley A. Ozenberger, Margaret L. Gulley, Jean C. Zenklusen, Inanc Birol, Christina Yau, Mark E. Sherman, Saianand Balu, Angela Hadjipanayis, Barry S. Taylor, Piotr A. Mieczkowski, Anthony Saleh, Carol G. Shores, Ezra E.W. Cohen, Joonil Jung, Ari B. Kahn, Lisa Wise, Peter S. Hammerman, Pei Lin, Marc Ladanyi, Mark C. Weissler, Scott L. Carter, Michele C. Hayward, Rehan Akbani, Todd Pihl, J. Jack Lee, Sophie C. Egea, Harshad S. Mahadeshwar, Leigh B. Thorne, Matthew G. Soloway, Troy Shelton, Andrea Haddad, William N. William, Wiktoria Maria Suchorska, Johanna Gardner, Marco A. Marra, Julie Ahn, Travis I. Zack, Lihua Zou, Bayardo Perez-Ordonez, David A. Wheeler, Daniel Crain, Adrian Ally, Deepak Srinivasan, Jay Bowen, Aaron D. Black, Jing Wang, Ludmila Danilova, Roy Tarnuzzer, Brenda Diergaarde, Tod D. Casasent, Dean Cheng, Giovanni Ciriello, Ken Burnett, Jeff Bruce, Wojciech Golusiński, Jonathan G. Seidman, Corbin D. Jones, Daniel J. Weisenberger, Lisa A. Peterson, Thomas M. Harris, Angeliki Pantazi, Nina Thiessen, Curtis R. Pickering, Chandra Sekhar Pedamallu, Yingchun Liu, William Lee, Andrzej Mackiewicz, Hailei Zhang, Ronglai Shen, B. Arman Aksoy, Lixing Yang, Jeffrey Roach, Simion I. Chiosea, John Waldron, David Van Den Berg, James Stephen Marron, Tanja Davidsen, Liming Yang, Maciej Wiznerowicz, Benjamin Gross, Paul M. Weinberger, Yufeng Liu, Reanne Bowlby, Zhixiang Zuo, Bartosz Szybiak, Roni J. Bollag, Samuel S. Freeman, Heather M. Walline, Gad Getz, Scott Morris, Michael S. Noble, Charles Saller, Sahil Seth, Richard A. Gibbs, Jonathan C. Irish, Hollie A. Harper, George E. Sandusky, S. Onur Sumer, Trevor Hackman, Gordon B. Mills, Carol R. Bradford, Payal Sipahimalani, Nipun Kakkar, Robert Penny, Jennifer Drummond, Adam M. Zanation, Rebecca Carlsen, Andrew J. Mungall, Harshavardhan Doddapaneni, James G. Herman, Sylvia Wrenn, Andy Chu, Nilsa C. Ramirez, Patrick Kwok Shing Ng, Patrick K. Kimes, Tina Wong, Mark E. Prince, Han Si, Kristian Cibulskis, Katherine Tarvin, Peter W. Laird, Jiabin Tang, Raja R. Seethala, Michael Parfenov, Jan F. Prins, Erin Curley, Hui Cheng, Donna M. Muzny, Lynda Chin, D. Neil Hayes, Margi Sheth, Carmen Gomez-Fernandez, Jessica Walton, Paul C. Boutros, Ariane Nguyen, Kristen M. Leraas, Robert L. Ferris, Greg Eley, Christopher C. Benz, Jaegil Kim, Thomas E. Carey, Douglas B. Chepeha, Janae V. Simons, Jiexin Zhang, Laura S. Rozek, Maureen A. Sartor, Christopher A. Bristow, Justin A. Bishop, Adel K. El-Naggar, Nishant Agrawal, Yiling Lu, Carrie Sougnez, Evan G. Taylor, Raju Kucherlapati, Scott M. Lippman, Colleen Mitchell, Wendell G. Yarbrough, Chu Chen, Donghui Tan, Bhishamjit S. Chera, Michael Mayo, Wenbin Liu, Ranabir Guin, W. Kimryn Rathmell, Mayya Malakh, Jessica Frick, John N. Weinstein, Kevin Lau, Michelle Q. Pham, Gideon Dresdner, Luc G. T. Morris, David Mallery, Zhining Wang, Yichao Sun, Lynn M. Herbert, Christine M. Komarck, Lauren Averett Byers, Angela Tam, Thomas Bodenheimer, Doug Voet, Christie Kovar, Junyuan Wu, Walker Hale, Charles M. Perou, Angela B.Y. Hui, Kenna R. Mills Shaw, Timothy J. Triche, Dong Zeng, Steven J.M. Jones, Matthew D. Wilkerson, Jinze Liu, Yan Guo, Hsu Chao, Tamara R. Jones, Katherine A. Hoadley, Stuart R. Jefferys, Thomas C. Motter, Matthew Meyerson, Konstanty Korski, Timothy A. Chan, Mark A. Jensen, Julien Baboud, Alexei Protopopov, David I. Heiman, Nils Gehlenborg, Heidi J. Sofia, Aaron D. Tward, Eric S. Lander, Yunhu Wan, Scot Waring, Peggy Yena, Robert I. Haddad, Daniel DiCara, Gordon Saksena, Juok Cho, Richard A. Moore, Darshan Singh, Peter J. Park, Matthew Ibbs, Robert A. Holt, Andrew D. Cherniack, Tanguy Y. Seiwert, Lee Lichtenstein, Anders Jacobsen, Rameen Beroukhim, Brandee T. Brown, Stephen C. Benz, Paweł Golusiński, Vonn Walter, Lixia Diao, Erik Zmuda, Scott Frazer, Michael S. Lawrence, Nils Weinhold, Jacqueline E. Schein, Xiaojia Ren, Denise Brooks, Elizabeth Buda, Jianjiong Gao, Jianhua Zhang, William W. Shockley, J. Todd Auman, Xingzhi Song, Jennifer R. Grandis, Jonathan B. McHugh, Stacey Gabriel, Martin L. Ferguson, Jeffrey S. Reid, Joseph Paulauskis, Umadevi Veluvolu, John A. Demchok, Moiz S. Bootwalla, Fei-Fei Liu, Alan P. Hoyle, Shaowu Meng, Mei Huang, Ann Marie Egloff, Christina Beard, Liu Xi, Ricardo Ramirez, Donna Morton, Lisle E. Mose, Leslie Cope, Marjorie Romkes, Zubair Khan, Noreen Dhalla, Candace Shelton, Boris Reva, Stephen B. Baylin, Miruna Balasundaram, Psalm Haseley, Andrew Wei Xu, Yan Shi, A. Gordon Robertson, Gregory T. Wolf, Darlene Lee, Steven E. Schumacher, Semin Lee, Rileen Sinha, Dennis T. Maglinte, Haiyan I. Li, William K. Funkhouser, Yi Han, Sam Ng, Joel S. Parker, Kai Wang, Zhong Chen, You Hong Fan, Yaron S.N. Butterfield, Jeffrey S. Moyer, Robert A. Burton, David Pot, Chris Sander, Daryl Waggott, Joseph A. Califano, Netty Santoso, Kyle Chang

المصدر: Nature

مصطلحات موضوعية: Male, DNA Copy Number Variations, Somatic cell, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, CDKN2A, Humans, HRAS, Molecular Targeted Therapy, RNA, Neoplasm, Gene, neoplasms, 030304 developmental biology, Genetics, 0303 health sciences, Multidisciplinary, Oncogene, Genome, Human, Squamous Cell Carcinoma of Head and Neck, Wnt signaling pathway, DNA, Neoplasm, Genomics, Oncogenes, Cell cycle, 3. Good health, Gene Expression Regulation, Neoplastic, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Mutation, Cancer research, Carcinoma, Squamous Cell, Female, FAT1, Signal Transduction, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5264ed4b1b32a6f914be04bca6cbd268Test
http://europepmc.org/articles/PMC4311405Test

المؤلفون: Yuanqing Ye, Jiabin Tang, Yu Cao, Neda Kalhor, Cesar A. Moran, John V. Heymach, William N. William, Jiexin Zhang, Waun Ki Hong, J. Jack Lee, Jianhua Zhang, Stephen G. Swisher, Ignacio I. Wistuba, Xifeng Wu, Huandong Sun, Jianjun Zhang, David C. Wedge, Alexei Protopopov, Latasha Little, Harshad S. Mahadeshwar, Andrew Futreal, Curtis Gumbs, Junya Fujimoto, Sahil Seth, Kathryn A. Gold, Chi Wan Chow, Xingzhi Song

المصدر: Science. 346:256-259

مصطلحات موضوعية: Lung Neoplasms, DNA Mutational Analysis, Adenocarcinoma of Lung, Adenocarcinoma, Biology, medicine.disease_cause, Article, Genomic Instability, Genetic Heterogeneity, Intratumor heterogeneity, Carcinoma, Non-Small-Cell Lung, medicine, Humans, Neoplasm, Exome, Gene, Mutation, Multidisciplinary, Lung, Genetic heterogeneity, medicine.disease, Phenotype, medicine.anatomical_structure, Cancer research, Cancer gene, Neoplasm Recurrence, Local, Genes, Neoplasm

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3052e3e841743895a8324973eaedb1Test
https://doi.org/10.1126/science.1256930Test

المؤلفون: Alexei Protopopov, Michael Ittmann, Yuexin Liu, Melanie H. Kucherlapati, Kang Jin Jeong, Yiqun Zhang, Lovelace J. Luquette, John N. Weinstein, Jonathan G. Seidman, Lynda Chin, Semin Lee, Yiu Huen Tsang, Huandong Sun, Carter Van Waes, Xiaojia Ren, Guillermo de Velasco, Christopher A. Bristow, Xingzhi Song, Rehan Akbani, Ruibin Xi, Patrick Kwok Shing Ng, Raju Kucherlapati, Lixing Yang, Chad J. Creighton, Jiabin Tang, Fengju Chen, Han Liang, Kenneth L. Scott, Andrew K. Godwin, Elizabeth P. Henske, Gordon B. Mills, Angeliki Pantazi, Sahil Seth, David J. Kwiatkowski, Toni K. Choueiri, Peter J. Park, Jianhua Zhang, Eunjung Lee, Thomas F. Westbrook, Angela Hadjipanayis, Carl Simon Shelley, Harshad S. Mahadeshwar

المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, pan-cancer analysis, STK11, The Cancer Genome Atlas, Article, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, proteomics, Neoplasms, Databases, Genetic, PTEN, Humans, reverse-phase protein arrays, Protein kinase B, Gene, PI3K/AKT/mTOR pathway, Proteogenomics, Genetics, integrative genomics analysis, biology, Gene Expression Profiling, TOR Serine-Threonine Kinases, RPTOR, Cell Biology, Survival Analysis, Gene expression profiling, 030104 developmental biology, Oncology, Mutation, biology.protein, Signal transduction, Proto-Oncogene Proteins c-akt, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65b7cf4a6b1dd31cbcf472d18e42170Test
https://hdl.handle.net/20.500.12530/41594Test

المؤلفون: Cameron W. Brennan, Roel G.W. Verhaak, Aaron McKenna, Benito Campos, Houtan Noushmehr, Sofie R. Salama, Siyuan Zheng, Debyani Chakravarty, J. Zachary Sanborn, Samuel H. Berman, Rameen Beroukhim, Brady Bernard, Chang-Jiun Wu, Giannicola Genovese, Ilya Shmulevich, Jill Barnholtz-Sloan, Lihua Zou, Rahulsimham Vegesna, Sachet A. Shukla, Giovanni Ciriello, W.K. Yung, Wei Zhang, Carrie Sougnez, Tom Mikkelsen, Kenneth Aldape, Darell D. Bigner, Erwin G. Van Meir, Michael Prados, Andrew Sloan, Keith L. Black, Jennifer Eschbacher, Gaetano Finocchiaro, William Friedman, David W. Andrews, Abhijit Guha, Mary Iacocca, Brian P. O’Neill, Greg Foltz, Jerome Myers, Daniel J. Weisenberger, Robert Penny, Raju Kucherlapati, Charles M. Perou, D. Neil Hayes, Richard Gibbs, Marco Marra, Gordon B. Mills, Eric Lander, Paul Spellman, Richard Wilson, Chris Sander, John Weinstein, Matthew Meyerson, Stacey Gabriel, Peter W. Laird, David Haussler, Gad Getz, Lynda Chin, Christopher Benz, Wendi Barrett, Quinn Ostrom, Yingli Wolinsky, Bikash Bose, Paul T. Boulos, Madgy Boulos, Jenn Brown, Christine Czerinski, Matthew Eppley, Thelma Kempista, Teresa Kitko, Yakov Koyfman, Brenda Rabeno, Pawan Rastogi, Michael Sugarman, Patricia Swanson, Kennedy Yalamanchii, Ilana P. Otey, Yingchun Spring Liu, Yonghong Xiao, J.Todd Auman, Peng-Chieh Chen, Angela Hadjipanayis, Eunjung Lee, Semin Lee, Peter J. Park, Jonathan Seidman, Lixing Yang, Steven Kalkanis, Laila M. Poisson, Aditya Raghunathan, Lisa Scarpace, Ryan Bressler, Andrea Eakin, Lisa Iype, Richard B. Kreisberg, Kalle Leinonen, Sheila Reynolds, Hector Rovira, Vesteinn Thorsson, Matti J. Annala, Joseph Paulauskis, Erin Curley, Martha Hatfield, David Mallery, Scott Morris, Troy Shelton, Candace Shelton, Mark Sherman, Peggy Yena, Lucia Cuppini, Francesco DiMeco, Marica Eoli, Emanuela Maderna, Bianca Pollo, Marco Saini, Saianand Balu, Katherine A. Hoadley, Ling Li, C. Ryan Miller, Yan Shi, Michael D. Topal, Junyuan Wu, Gavin Dunn, Caterina Giannini, Brian P. O'Neill, B. Arman Aksoy, Yevgeniy Antipin, Laetitia Borsu, Ethan Cerami, Jianjiong Gao, Benjamin Gross, Anders Jacobsen, Marc Ladanyi, Alex Lash, Yupu Liang, Boris Reva, Nikolaus Schultz, Ronglai Shen, Nicholas D. Socci, Agnes Viale, Martin L. Ferguson, Qing-Rong Chen, John A. Demchok, Laura A.L. Dillon, Kenna R. Mills Shaw, Margi Sheth, Roy Tarnuzzer, Zhining Wang, Liming Yang, Tanja Davidsen, Mark S. Guyer, Bradley A. Ozenberger, Heidi J. Sofia, Julie Bergsten, John Eckman, Jodi Harr, Christine Smith, Kelly Tucker, Cindy Winemiller, Leigh Anne Zach, Julia Y. Ljubimova, Greg Eley, Brenda Ayala, Mark A. Jensen, Ari Kahn, Todd D. Pihl, David A. Pot, Yunhu Wan, Nathan Hansen, Parvi Hothi, Biaoyang Lin, Nameeta Shah, Jae-geun Yoon, Ching Lau, Michael Berens, Kristin Ardlie, Scott L. Carter, Andrew D. Cherniack, Mike Noble, Juok Cho, Kristian Cibulskis, Daniel DiCara, Scott Frazer, Stacey B. Gabriel, Nils Gehlenborg, Jeff Gentry, David Heiman, Jaegil Kim, Rui Jing, Eric S. Lander, Michael Lawrence, Pei Lin, Will Mallard, Robert C. Onofrio, Gordon Saksena, Steve Schumacher, Petar Stojanov, Barbara Tabak, Doug Voet, Hailei Zhang, Nathan N. Dees, Li Ding, Lucinda L. Fulton, Robert S. Fulton, Krishna-Latha Kanchi, Elaine R. Mardis, Richard K. Wilson, Stephen B. Baylin, Larry Harshyne, Mark L. Cohen, Karen Devine, Andrew E. Sloan, Scott R. VandenBerg, Mitchel S. Berger, Daniel Carlin, Brian Craft, Kyle Ellrott, Mary Goldman, Theodore Goldstein, Mia Grifford, Singer Ma, Sam Ng, Joshua Stuart, Teresa Swatloski, Peter Waltman, Jing Zhu, Robin Foss, Barbara Frentzen, Raquel McTiernan, Anthony Yachnis, Yong Mao, Rehan Akbani, Oliver Bogler, Gregory N. Fuller, Wenbin Liu, Yuexin Liu, Yiling Lu, Gordon Mills, Alexei Protopopov, Xiaojia Ren, Youting Sun, W.K. Alfred Yung, Jianhua Zhang, Ken Chen, John N. Weinstein, Moiz S. Bootwalla, Phillip H. Lai, Timothy J. Triche, David J. Van Den Berg, David H. Gutmann, Norman L. Lehman, Erwin G. VanMeir, Daniel Brat, Jeffrey J. Olson, Gena M. Mastrogianakis, Narra S. Devi, Zhaobin Zhang, Darell Bigner, Eric Lipp, Roger McLendon

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: Male, Telomerase, Proteome, REGULAÇÃO GÊNICA, Somatic cell, Mesenchymal Glioblastoma, PDGFRA, Computational biology, Biology, medicine.disease_cause, Article, General Biochemistry, Genetics and Molecular Biology, medicine, Humans, Gene Regulatory Networks, Gene, Genetics, Glioblastoma cell, Mutation, Brain Neoplasms, Biochemistry, Genetics and Molecular Biology(all), Gene Expression Profiling, Phenotype, Gene expression profiling, DNA methylation, Cancer research, Female, Glioblastoma, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6a01be1b6ad71e670249f202697e6aTest

المؤلفون: Eric S. Martin, Andrew J. Aguirre, Ronald A. DePinho, Hongbin Ji, Giovanni Tonon, Mingjian James You, Cameron Brennan, Gautam Maulik, Z. Yang, Lynda Chin, Yunyu Zhang, Bin Feng, Deepak B. Khatry, Alexei Protopopov, Kwok-Kin Wong

المساهمون: Tonon, G, Brennan, C, Protopopov, A, Maulik, G, Feng, B, Zhang, Y, Khatry, Db, You, Mj, Aguirre, Aj, Martin, E, Yang, Z, Ji, H, Chin, L, Wong, Kk, Depinho, Ra

المصدر: Cold Spring Harbor Symposia on Quantitative Biology. 70:11-24

مصطلحات موضوعية: Lung Neoplasms, Cellular differentiation, Gene Dosage, Adenocarcinoma, Biology, Biochemistry, Cytogenetics, Carcinoma, Non-Small-Cell Lung, Genetics, medicine, Humans, Lung cancer, Molecular Biology, Gene, In Situ Hybridization, Fluorescence, Gene Expression Profiling, Membrane Proteins, Oncogenes, Amplicon, medicine.disease, Phenotype, Gene expression profiling, Chromosome 3, Carcinoma, Squamous Cell, Chromosomes, Human, Pair 3

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7ab9fc0c8248272ae4ebae56d430e5Test
https://doi.org/10.1101/sqb.2005.70.021Test

المؤلفون: Michele Ceccarelli, Floris P. Barthel, Tathiane M. Malta, Thais S. Sabedot, Sofie R. Salama, Bradley A. Murray, Olena Morozova, Yulia Newton, Amie Radenbaugh, Stefano M. Pagnotta, Samreen Anjum, Jiguang Wang, Ganiraju Manyam, Pietro Zoppoli, Shiyun Ling, Arjun A. Rao, Mia Grifford, Andrew D. Cherniack, Hailei Zhang, Laila Poisson, Carlos Gilberto Carlotti, Daniela Pretti da Cunha Tirapelli, Arvind Rao, Tom Mikkelsen, Ching C. Lau, W.K. Alfred Yung, Raul Rabadan, Jason Huse, Daniel J. Brat, Norman L. Lehman, Jill S. Barnholtz-Sloan, Siyuan Zheng, Kenneth Hess, Ganesh Rao, Matthew Meyerson, Rameen Beroukhim, Lee Cooper, Rehan Akbani, Margaret Wrensch, David Haussler, Kenneth D. Aldape, Peter W. Laird, David H. Gutmann, Houtan Noushmehr, Antonio Iavarone, Roel G.W. Verhaak, Harindra Arachchi, J. Todd Auman, Miruna Balasundaram, Saianand Balu, Gene Barnett, Stephen Baylin, Sue Bell, Christopher Benz, Natalie Bir, Keith L. Black, Tom Bodenheimer, Lori Boice, Moiz S. Bootwalla, Jay Bowen, Christopher A. Bristow, Yaron S.N. Butterfield, Qing-Rong Chen, Lynda Chin, Juok Cho, Eric Chuah, Sudha Chudamani, Simon G. Coetzee, Mark L. Cohen, Howard Colman, Marta Couce, Fulvio D’Angelo, Tanja Davidsen, Amy Davis, John A. Demchok, Karen Devine, Li Ding, Rebecca Duell, J. Bradley Elder, Jennifer M. Eschbacher, Ashley Fehrenbach, Martin Ferguson, Scott Frazer, Gregory Fuller, Jordonna Fulop, Stacey B. Gabriel, Luciano Garofano, Julie M. Gastier-Foster, Nils Gehlenborg, Mark Gerken, Gad Getz, Caterina Giannini, William J. Gibson, Angela Hadjipanayis, D. Neil Hayes, David I. Heiman, Beth Hermes, Joe Hilty, Katherine A. Hoadley, Alan P. Hoyle, Mei Huang, Stuart R. Jefferys, Corbin D. Jones, Steven J.M. Jones, Zhenlin Ju, Alison Kastl, Ady Kendler, Jaegil Kim, Raju Kucherlapati, Phillip H. Lai, Michael S. Lawrence, Semin Lee, Kristen M. Leraas, Tara M. Lichtenberg, Pei Lin, Yuexin Liu, Jia Liu, Julia Y. Ljubimova, Yiling Lu, Yussanne Ma, Dennis T. Maglinte, Harshad S. Mahadeshwar, Marco A. Marra, Mary McGraw, Christopher McPherson, Shaowu Meng, Piotr A. Mieczkowski, C. Ryan Miller, Gordon B. Mills, Richard A. Moore, Lisle E. Mose, Andrew J. Mungall, Rashi Naresh, Theresa Naska, Luciano Neder, Michael S. Noble, Ardene Noss, Brian Patrick O’Neill, Quinn T. Ostrom, Cheryl Palmer, Angeliki Pantazi, Michael Parfenov, Peter J. Park, Joel S. Parker, Charles M. Perou, Christopher R. Pierson, Todd Pihl, Alexei Protopopov, Nilsa C. Ramirez, W. Kimryn Rathmell, Xiaojia Ren, Jeffrey Roach, A. Gordon Robertson, Gordon Saksena, Jacqueline E. Schein, Steven E. Schumacher, Jonathan Seidman, Kelly Senecal, Sahil Seth, Hui Shen, Yan Shi, Juliann Shih, Kristen Shimmel, Hugues Sicotte, Suzanne Sifri, Tiago Silva, Janae V. Simons, Rosy Singh, Tara Skelly, Andrew E. Sloan, Heidi J. Sofia, Matthew G. Soloway, Xingzhi Song, Carrie Sougnez, Camila Souza, Susan M. Staugaitis, Huandong Sun, Charlie Sun, Donghui Tan, Jiabin Tang, Yufang Tang, Leigh Thorne, Felipe Amstalden Trevisan, Timothy Triche, David J. Van Den Berg, Umadevi Veluvolu, Doug Voet, Yunhu Wan, Zhining Wang, Ronald Warnick, John N. Weinstein, Daniel J. Weisenberger, Matthew D. Wilkerson, Felicia Williams, Lisa Wise, Yingli Wolinsky, Junyuan Wu, Andrew W. Xu, Lixing Yang, Liming Yang, Travis I. Zack, Jean C. Zenklusen, Jianhua Zhang, Wei Zhang, Jiashan Zhang, Erik Zmuda

المساهمون: Ceccarelli, M, Barthel, Fp, Malta, Tm, Sabedot, T, Salama, Sr, Murray, Ba, Morozova, O, Newton, Y, Radenbaugh, A, Pagnotta, Sm, Anjum, S, Wang, Jg, Manyam, G, Zoppoli, P, Ling, S, Rao, Aa, Grifford, M, Cherniack, Ad, Zhang, Hl, Poisson, L, Carlotti, Cg, Tirapelli, Dpd, Rao, A, Mikkelsen, T, Lau, Cc, Yung, Wka, Rabadan, R, Huse, J, Brat, Dj, Lehman, Nl, Barnholtz-Sloan, J, Zheng, S, Hess, K, Rao, G, Meyerson, M, Beroukhim, R, Cooper, L, Akbani, R, Wrensch, M, Haussler, D, Aldape, Kd, Laird, Pw, Gutmann, Dh, Noushmehr, H, Iavarone, A, Verhaak, Rgw, Neurosurgery

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Ceccarelli, M, Barthel, F P, Malta, T M, Sabedot, T S, Salama, S R, Murray, B A, Morozova, O, Newton, Y, Radenbaugh, A, Pagnotta, S M, Anjum, S, Wang, J, Manyam, G, Zoppoli, P, Ling, S, Rao, A A, Grifford, M, Cherniack, A D, Zhang, H, Poisson, L, Carlotti, C G J, Tirapelli, D P D C, Rao, A, Mikkelsen, T, Lau, C C, Yung, W K A, Rabadan, R, Huse, J, Brat, D J, Lehman, N L, Barnholtz-Sloan, J S, Zheng, S, Hess, K, Rao, G, Meyerson, M, Beroukhim, R, Cooper, L, Akbani, R, Wrensch, M, Haussler, D, Aldape, K D, Laird, P W, Gutmann, D H, Noushmehr, H, Iavarone, A & Verhaak, R G W 2016, ' Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma ', Cell, vol. 164, no. 3, pp. 550-563 . https://doi.org/10.1016/j.cell.2015.12.028Test
Cell, 164(3), 550-563. Cell Press

مصطلحات موضوعية: 0301 basic medicine, Adult, X-linked Nuclear Protein, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Epigenesis, Genetic, Transcriptome, 03 medical and health sciences, Diffuse Glioma, Glioma, medicine, Cluster Analysis, Humans, Promoter Regions, Genetic, Gene, Telomerase, ATRX, Cell Proliferation, Pilocytic astrocytoma, Biochemistry, Genetics and Molecular Biology(all), Brain Neoplasms, MUTAÇÃO GENÉTICA, DNA Helicases, Nuclear Proteins, DNA Methylation, Middle Aged, Telomere, medicine.disease, Isocitrate Dehydrogenase, 3. Good health, 030104 developmental biology, DNA demethylation, DNA methylation, Mutation, Cancer research, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632ac454203f4f8d554b72918f8683a4Test