-
1
المؤلفون: Joel D. Leverson, Naoki Osada, Yusuke Furukawa, Jiro Kikuchi, Yoshiaki Kuroda, Hiroshi Yasui, Daisuke Koyama
المصدر: Haematologica
مصطلحات موضوعية: Sulfonamides, Venetoclax, business.industry, TOR Serine-Threonine Kinases, Hematology, MTOR Inhibitors, Discovery and development of mTOR inhibitors, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, IKZF3, Up-Regulation, chemistry.chemical_compound, Ikaros Transcription Factor, chemistry, Downregulation and upregulation, Proto-Oncogene Proteins c-bcl-2, Cell Line, Tumor, Cancer research, Medicine, Humans, business, Letters to the Editor, Multiple Myeloma, Multiple myeloma
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989d9cea5882c1907624c4d1654ef05eTest
http://europepmc.org/articles/PMC8561283Test -
2
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 1016-1027 (2021)
Neoplasia (New York, N.Y.)مصطلحات موضوعية: Cancer Research, 4E-BP1, Antineoplastic Agents, Jurkat Cells, chemistry.chemical_compound, hemic and lymphatic diseases, Tumor Cells, Cultured, medicine, Humans, Philadelphia Chromosome, Protein kinase B, PI3K/AKT/mTOR pathway, RC254-282, Original Research, ABL, Dose-Response Relationship, Drug, TOR Serine-Threonine Kinases, Ponatinib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Imatinib, MTOR Inhibitors, Oncogenes, Precursor Cell Lymphoblastic Leukemia-Lymphoma, BCR-ABL1, Dasatinib, Adult Acute Lymphoblastic Leukemia, chemistry, Nilotinib, Oncogene independent resistance, Drug Resistance, Neoplasm, Cancer research, AKT/mTOR pathway, Proto-Oncogene Proteins c-akt, Tyrosine kinase, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbfb48714062bf527043a3ebbe462feTest
http://www.sciencedirect.com/science/article/pii/S1476558621000646Test -
3
المؤلفون: David Ebuka Arthur, Jibrin Noah Akoji, Riadh Sahnoun, Greatman C. Okafor, Karimatu Lami Abdullahi, Charles Mgbemena, Samira A. Abdullahi
المصدر: Bulletin of the National Research Centre, Vol 45, Iss 1, Pp 1-12 (2021)
مصطلحات موضوعية: Stereochemistry, Hydrogen interaction, Binding energy, Food and drug administration, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Mole, Receptor, lcsh:Science, PI3K/AKT/mTOR pathway, 030304 developmental biology, General Environmental Science, SBDD, 0303 health sciences, Hydrogen bond, Hydrophobic interaction, Ligand (biochemistry), Discovery and development of mTOR inhibitors, chemistry, 030220 oncology & carcinogenesis, Molecular docking, General Earth and Planetary Sciences, lcsh:Q, Drug, Adenosine triphosphate
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b530a5f1e6a6450dd168e97d15f717Test
https://doaj.org/article/89f67ef9a17f43c58284770b1b9814d9Test -
4
المؤلفون: Tiffany Shaw, Hannah Lee, Robert A. Figlin
المصدر: ONCOLOGY. :306-310
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Cabozantinib, medicine.medical_treatment, Ipilimumab, chemistry.chemical_compound, Antineoplastic Agents, Immunological, Renal cell carcinoma, Internal medicine, Basic Helix-Loop-Helix Transcription Factors, medicine, Humans, Carcinoma, Renal Cell, Protein Kinase Inhibitors, Randomized Controlled Trials as Topic, Everolimus, business.industry, MTOR Inhibitors, Immunotherapy, medicine.disease, Kidney Neoplasms, respiratory tract diseases, Axitinib, chemistry, Practice Guidelines as Topic, Nivolumab, business, Lenvatinib, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2384827fee72ba75eb3766c87f599354Test
https://doi.org/10.46883/onc.2021.3506.0306Test -
5
المؤلفون: Matteo Santoni, Camillo Porta, Mimma Rizzo
المصدر: Journal of Onco-Nephrology. 4:153-164
مصطلحات موضوعية: 0301 basic medicine, business.industry, medicine.medical_treatment, Immunotherapy, medicine.disease, Discovery and development of mTOR inhibitors, Vascular endothelial growth factor, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, Renal cell carcinoma, 030220 oncology & carcinogenesis, Cancer research, Medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::10ef544052cb0af64cfaa698fd6f745cTest
https://doi.org/10.1177/2399369320943609Test -
6
المؤلفون: James A. McCubrey, Maria Sofia Basile, José Francisco Muñoz-Valle, Paolo Fagone, Jorge Hernández-Bello, Ferdinando Nicoletti, Eugenio Cavalli
المصدر: Drug Discovery Today
مصطلحات موضوعية: mTOR inhibitors, In silico, Cell, Akt inhibitors, Antiviral Agents, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, Downregulation and upregulation, In vivo, Drug Discovery, medicine, Animals, Humans, Phosphatidylinositol, Protein kinase B, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Pharmacology, business.industry, SARS-CoV-2, TOR Serine-Threonine Kinases, COVID-19, PI3K inhibitors, In vitro, PI3K/Akt/mTOR pathway, COVID-19 Drug Treatment, medicine.anatomical_structure, chemistry, Cancer research, business, Post-Screen (Grey), Proto-Oncogene Proteins c-akt, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c636e10507f558b21b8a0d484f73ebf8Test
http://europepmc.org/articles/PMC8574122Test -
7
المؤلفون: Nicola Fusco, Antonio Ghidini, Gianluca Tomasello, Francesco Grossi, Fausto Petrelli, Andrea Botticelli, Michele Ghidini, Giulia Grizzi, Tommaso Savio, Mary Cabiddu
المصدر: Cancer Management and Research, Vol Volume 12, Pp 675-686 (2020)
Cancer Management and Researchمصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Estrogen receptor, Review, Palbociclib, lcsh:RC254-282, Aromatase inhibitors, Breast cancer, CDK 4/6 inhibitors, MTOR inhibitors, Neoadjuvant endocrine therapy, PI3K inhibitors, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Abemaciclib, Everolimus, business.industry, Cancer, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Hormonal therapy, business, Tamoxifen, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1827d1c140e47f6f8a458a2962ff8f54Test
https://doi.org/10.2147/cmar.s202965Test -
8
المؤلفون: Yujia Xu, Yan Li, Wen Zhao, Pengju Wang, Yalin Zhang, Zhaoming Lu, Huiyun Wei, Guiqin Hou
مصطلحات موضوعية: Indoles, Esophageal Neoplasms, Cell, Models, Biological, Cell cycle phase, Immunophenotyping, chemistry.chemical_compound, Mice, Isothiocyanates, Cell Line, Tumor, Genetics, medicine, Animals, Humans, MTT assay, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Cell growth, TOR Serine-Threonine Kinases, Drug Synergism, General Medicine, MTOR Inhibitors, Xenograft Model Antitumor Assays, digestive system diseases, Disease Models, Animal, medicine.anatomical_structure, chemistry, Apoptosis, Purines, Sulfoxides, Cancer research, Proto-Oncogene Proteins c-akt, Sulforaphane, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6507f0840ddbe107eb36d18ecd86e45Test
https://doi.org/10.21203/rs.3.rs-892848/v1Test -
9
المؤلفون: Shao-Pei Hung, Wen-Chin Lee, Hsiang-Hao Hsu, Jin-Bor Chen, You-Ying Chau, Terry Ting-Yu Chiou
المصدر: Biomedicine & Pharmacotherapy, Vol 144, Iss, Pp 112349-(2021)
Chioua, T T-Y, Chau, Y-Y, Chen, J-B, Hsu, H-H, Huang, S-P & Lee, W-C 2021, ' Rapamycin attenuates PLA2R activation-mediated podocyte apoptosis via the PI3K/AKT/mTOR pathway ', Biomedicine and Pharmacotherapy, vol. 144 . https://doi.org/10.1016/j.biopha.2021.112349Testمصطلحات موضوعية: Membranous nephropathy, Apoptosis Regulatory Proteins/metabolism, Phospholipase A2 receptor, Podocyte, Apoptosis, RM1-950, Glomerulonephritis, Membranous, Cell Line, chemistry.chemical_compound, Downregulation and upregulation, Proto-Oncogene Proteins c-akt/metabolism, medicine, Humans, LY294002, Protein kinase B, PI3K/AKT/mTOR pathway, Sirolimus, MTOR Inhibitors/pharmacology, Pharmacology, TOR Serine-Threonine Kinases/antagonists & inhibitors, Mammalian target of rapamycin, biology, Podocytes, Chemistry, Receptors, Phospholipase A2, TOR Serine-Threonine Kinases, Cytochrome c, Apoptosis/drug effects, Sirolimus/pharmacology, MTOR Inhibitors, General Medicine, Enzyme Activation, Crosstalk (biology), Receptors, Phospholipase A2/metabolism, medicine.anatomical_structure, Cancer research, biology.protein, Therapeutics. Pharmacology, Phosphatidylinositol 3-Kinase, Podocytes/drug effects, Apoptosis Regulatory Proteins, Proto-Oncogene Proteins c-akt, Phosphatidylinositol 3-Kinase/metabolism, Glomerulonephritis, Membranous/drug therapy, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9d35f5abc372da2d816d2bcd3713e5Test
https://doi.org/10.1016/j.biopha.2021.112349Test -
10
المؤلفون: Guoli Shi, Abhilash I. Chiramel, Tiansheng Li, Kin Kui Lai, Adam D. Kenney, Ashley Zani, Adrian C. Eddy, Saliha Majdoul, Lizhi Zhang, Tirhas Dempsey, Paul A. Beare, Swagata Kar, Jonathan W. Yewdell, Sonja M. Best, Jacob S. Yount, Alex A. Compton
المصدر: bioRxiv
article-version (status) pre
article-version (number) 1مصطلحات موضوعية: Intrinsic immunity, mTOR inhibitor, Cell, membrane fusion, coronavirus, medicine.disease_cause, rapalog, Virus, Article, IFITM, Ridaforolimus, chemistry.chemical_compound, Immune system, Immunopathology, medicine, Influenza A virus, Humans, SARS, Sirolimus, business.industry, rapamycin, SARS-CoV-2, fungi, COVID-19, Membrane Proteins, RNA-Binding Proteins, General Medicine, interferon, MTOR Inhibitors, Virus Internalization, Acquired immune system, Influenza, Immunity, Innate, medicine.anatomical_structure, chemistry, Cancer research, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681ff4acf303d40082d1e4292bf4dabaTest
https://pubmed.ncbi.nlm.nih.gov/36264642Test
