نتائج البحث

1

Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated

المؤلفون: Knut Dahl-Jørgensen, Shiva Reddy, Lars Krogvold, Owen Martin, Charlton Martin, Kevin Xueying Sun, Aamenah Al-Ani

المصدر: Cell and Tissue Research. 384:655-674

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, endocrine system, medicine.medical_specialty, Histology, Adolescent, endocrine system diseases, Nitric Oxide Synthase Type II, Nitric Oxide, Glucagon, Pathology and Forensic Medicine, Proinflammatory cytokine, Nitric oxide, Islets of Langerhans, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Humans, Beta (finance), Cells, Cultured, Type 1 diabetes, geography, geography.geographical_feature_category, biology, Chemistry, Cell Biology, medicine.disease, Islet, Nitric oxide synthase, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, biology.protein, Female, Beta cell, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6728a9832de8ac370bf9e4176fa86c25Test
https://doi.org/10.1007/s00441-020-03340-4Test

2

ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer's disease

المؤلفون: Franco Bernini, Maria Pia Adorni, Francesca Zimetti, Daniela Galimberti, Paolo Caffarra, Cinzia Marchi, Marco Spallazzi, Nicoletta Ronda, Federica Barocco

المصدر: Journal of Lipid Research, Vol 60, Iss 8, Pp 1449-1456 (2019)
J Lipid Res

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, Adult, Male, medicine.medical_specialty, apolipoprotein A-I, QD415-436, 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Cerebrospinal fluid, Alzheimer Disease, Internal medicine, medicine, Dementia, Humans, ATP Binding Cassette Transporter, Subfamily G, Member 1, Aged, apolipoprotein E, ATP-binding cassette A1, Amyloid beta-Peptides, biology, Cholesterol, business.industry, Neurodegeneration, ATP-binding cassette G1, Cell Biology, Middle Aged, apolipoprotein E4, medicine.disease, Pathophysiology, Peptide Fragments, 030104 developmental biology, chemistry, ABCA1, biology.protein, cardiovascular system, Female, lipids (amino acids, peptides, and proteins), Efflux, business, Patient-Oriented and Epidemiological Research, apolipoproteins, ATP Binding Cassette Transporter 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32af647e6d95ae13ea957fc028bbe95Test
http://www.sciencedirect.com/science/article/pii/S0022227520322392Test

3

The cAMP pathway promotes sirtuin-1 expression in human granulosa-lutein cells

المؤلفون: Ketan Shrestha, Avi Harlev, Rina Meidan, Eliezer Girsh, Magdalena Szymanska, Sarah Manthe

المصدر: Reproductive Biology. 20:273-281

مصطلحات موضوعية: Adult, 0301 basic medicine, animal structures, endocrine system diseases, Carbazoles, Enzyme Activators, Heterocyclic Compounds, 2-Ring, Cell Line, Adenylyl cyclase, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Sirtuin 1, Luteal Cells, Cyclic AMP, Humans, RNA, Small Interfering, Granulosa Lutein Cell, Gene knockdown, Granulosa Cells, 030219 obstetrics & reproductive medicine, Forskolin, Dose-Response Relationship, Drug, biology, Colforsin, food and beverages, Phosphodiesterase, Cell biology, enzymes and coenzymes (carbohydrates), 030104 developmental biology, chemistry, Resveratrol, biology.protein, cAMP-dependent pathway, Female, Animal Science and Zoology, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, Developmental Biology, Deacetylase activity

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba58c84c9e837291a7444de6dfe0710Test
https://doi.org/10.1016/j.repbio.2020.07.010Test

4

Association of placental nutrient sensing pathways with birth weight

المؤلفون: Maria-Luisa Lazo-de-la-Vega-Monroy, Hector-Manuel Gomez-Zapata, Juan-Antonio Garcia-Santillan, Maria-Angelica Corona-Figueroa, Gloria Barbosa-Sabanero, J. M. Malacara, Martha-Isabel Gonzalez-Dominguez, Leonel Daza-Benítez, Karen-Alejandra Mata-Tapia

المصدر: Reproduction. 160:455-468

مصطلحات موضوعية: Adult, Leptin, 0301 basic medicine, Embryology, medicine.medical_specialty, Adolescent, Placenta, medicine.medical_treatment, Body Mass Index, Receptor, IGF Type 1, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Pregnancy, Internal medicine, medicine, Birth Weight, Humans, Insulin-Like Growth Factor I, Mechanistic target of rapamycin, Protein kinase B, PI3K/AKT/mTOR pathway, 030219 obstetrics & reproductive medicine, biology, TOR Serine-Threonine Kinases, Insulin, Infant, Newborn, Obstetrics and Gynecology, AMPK, Nutrients, Cell Biology, Cross-Sectional Studies, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, Reproductive Medicine, Cord blood, biology.protein, Female, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93608e055cb7d4600122c65cfdbd5a1Test
https://doi.org/10.1530/rep-20-0186Test

5

GRHL2 induces liver fibrosis and intestinal mucosal barrier dysfunction in non‐alcoholic fatty liver disease via microRNA‐200 and the MAPK pathway

المؤلفون: Lin Guan, Zishu Zeng, Ran Ao, Ying Wang

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: Liver Cirrhosis, Male, 0301 basic medicine, MAPK/ERK pathway, Occludin, chemistry.chemical_compound, sirtuin‐1, 0302 clinical medicine, Sirtuin 1, Non-alcoholic Fatty Liver Disease, Medicine, Intestinal Mucosa, transcription factor, liver fibrosis, biology, Fatty liver, microRNA‐200, Middle Aged, DNA-Binding Proteins, 030220 oncology & carcinogenesis, Molecular Medicine, Female, Original Article, Adult, non‐alcoholic fatty liver disease, medicine.medical_specialty, MAP Kinase Signaling System, Grainyhead‐like 2, Models, Biological, digestive system, Young Adult, 03 medical and health sciences, Insulin resistance, Internal medicine, microRNA, Animals, Humans, Gene Silencing, Triglyceride, MAPK signalling pathway, business.industry, intestinal mucosal barrier dysfunction, Cell Biology, Original Articles, medicine.disease, digestive system diseases, Mice, Inbred C57BL, MicroRNAs, 030104 developmental biology, Endocrinology, Gene Expression Regulation, chemistry, biology.protein, Ectopic expression, business, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0613520c85020896855175e6eac7dd91Test
http://europepmc.org/articles/PMC7294114Test

6

Pregnancy‐associated venous insufficiency course with placental and systemic oxidative stress

المؤلفون: Julia Buján, Felipe Sainz, Coral Bravo, Clara Martinez-Vivero, Juan De León-Luis, Miguel A Ortega, Natalio García-Honduvilla, Melchor Alvarez-Mon, Beatriz Romero, Ángel Asúnsolo

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Placenta, Poly (ADP-Ribose) Polymerase-1, Nitric Oxide Synthase Type II, medicine.disease_cause, chemistry.chemical_compound, 0302 clinical medicine, Pregnancy, Enos, chemistry.chemical_classification, biology, Malondialdehyde, Nitric oxide synthase, ERK, medicine.anatomical_structure, 030220 oncology & carcinogenesis, NOX1, NADPH Oxidase 1, Molecular Medicine, Gestation, Female, Original Article, Poly(ADP-ribose) Polymerases, Adult, malondialdehyde, medicine.medical_specialty, PARP, 03 medical and health sciences, NOX2, Internal medicine, medicine, Humans, Lower extremity venous insufficiency, Reactive oxygen species, business.industry, Pregnancy Complications, Hematologic, inducible nitric oxide synthase, Original Articles, Cell Biology, biology.organism_classification, Oxidative Stress, 030104 developmental biology, Endocrinology, Venous Insufficiency, chemistry, biology.protein, Reactive Oxygen Species, business, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e85ac5f98fc6025cde6872967913e3Test
https://doi.org/10.1111/jcmm.15077Test

7

The interaction between ABCA1 polymorphism and physical activity on the HDL-cholesterol levels in a Japanese population

المصدر: Journal of Lipid Research, Vol 61, Iss 1, Pp 86-94 (2020)
J Lipid Res

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Single-nucleotide polymorphism, QD415-436, 030204 cardiovascular system & hematology, Polymorphism, Single Nucleotide, Biochemistry, 03 medical and health sciences, symbols.namesake, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Japan, Polymorphism (computer science), Internal medicine, Epidemiology, medicine, Humans, genetics, Allele, Alleles, Aged, biology, exercise, business.industry, Cholesterol, Cholesterol, HDL, nutritional and metabolic diseases, Cell Biology, Middle Aged, 030104 developmental biology, Bonferroni correction, chemistry, ABCA1, biology.protein, symbols, Female, lipids (amino acids, peptides, and proteins), epidemiology, high density lipoprotein-cholesterol, Patient-Oriented and Epidemiological Research, business, polymorphisms, cholesterol efflux, ATP Binding Cassette Transporter 1, Cohort study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e129a6fec184c9abc71f8a04cfc610Test
http://www.sciencedirect.com/science/article/pii/S0022227520300183Test

8

Apolipoprotein-defined lipoprotein subclasses, serum apolipoproteins, and carotid intima-media thickness in T1D

المؤلفون: W. Timothy Garvey, Complications Trial, Jamie R. Wood, Petar Alaupovic, Arpita Basu, Timothy J. Lyons, David S. Schade, Julie A. Stoner, Ying Zhang, Richard L. Klein, Alicia J. Jenkins, Diabetes Control, Maria F. Lopes-Virella

المصدر: Journal of Lipid Research, Vol 59, Iss 5, Pp 872-883 (2018)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Apolipoprotein B, Cross-sectional study, type 1 diabetes, 030209 endocrinology & metabolism, Type 2 diabetes, QD415-436, 030204 cardiovascular system & hematology, Carotid Intima-Media Thickness, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Apolipoprotein-A-I, Diabetes mellitus, Internal medicine, medicine, Humans, cardiovascular diseases, Type 1 diabetes, biology, business.industry, Cell Biology, medicine.disease, Apolipoprotein-C-III carotid intima-media thickness, Apolipoproteins, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Intima-media thickness, Cardiology, Albuminuria, biology.protein, cardiovascular system, Regression Analysis, Female, lipids (amino acids, peptides, and proteins), medicine.symptom, business, Patient-Oriented and Epidemiological Research, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54785dd00c0ab15c3d27873a9fc1133fTest
http://www.sciencedirect.com/science/article/pii/S0022227520331229Test

9

Altered HDL proteome predicts incident CVD in chronic kidney disease patients

المؤلفون: Baohai Shao, Anna V. Mathew, Carissa Thornock, Subramaniam Pennathur, Matthias Kretzler, Debbie Gipson, Markus Bitzer, Crystal Gadegbeku, Keith Bellovich, Zeenat Bhat, Susan Massengill, Kalyani Perumal

المصدر: Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100135-(2021)

مصطلحات موضوعية: Male, HD, hemodialysis, Biochemistry, Gastroenterology, APOA4, apolipoprotein A-IV, Phosphatidylcholine-Sterol O-Acyltransferase, chemistry.chemical_compound, Endocrinology, High-density lipoprotein, ESRD, end-stage renal disease, PRM, parallel reaction monitoring, Medicine, Aged, 80 and over, Proteinuria, biology, eGFR, estimated glomerular filtration rate, Middle Aged, CVD, Cardiovascular Diseases, CRP, C-reactive protein, Regression Analysis, APOC3, apolipoprotein C-III, lipids (amino acids, peptides, and proteins), Female, medicine.symptom, Lipoproteins, HDL, Research Article, Adult, medicine.medical_specialty, matched logistic regression analysis, HDL, case-control study, CPROBE, Clinical Phenotyping and Resource Biobank Core, Renal function, PON3, paraoxonase/arylesterase 3, QD415-436, End stage renal disease, Internal medicine, CKD, Humans, Renal Insufficiency, Chronic, Apolipoproteins A, Aged, business.industry, Aryldialkylphosphatase, C-reactive protein, APOA1, apolipoprotein A-I, CKD, chronic kidney disease, Case-control study, Cell Biology, Odds ratio, MS, medicine.disease, PON1, paraoxonase/arylesterase 1, OR, odds ratio, parallel reaction monitoring, chemistry, biology.protein, HDL-C levels, HDL proteomics, business, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87de69cbed2920675daa3f2993ac5df5Test
https://pubmed.ncbi.nlm.nih.gov/34634315Test

10

Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease

المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze

المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec108ccaaae2e081b54e4ea79fe8b459Test

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