Yessotoxin, a Promising Therapeutic Tool
| العنوان: | Yessotoxin, a Promising Therapeutic Tool |
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| المؤلفون: | Mercedes R. Vieytes, Amparo Alfonso, Luis M. Botana |
| المساهمون: | Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, Universidade de Santiago de Compostela. Departamento de Fisioloxía |
| المصدر: | Marine Drugs, Vol 14, Iss 2, p 30 (2016) Marine Drugs Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela instname |
| بيانات النشر: | MDPI AG, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, Pharmaceutical Science, Apoptosis, Review, Signal transduction, Pharmacology, Bioinformatics, medicine.disease_cause, Second Messenger Systems, cellular death, chemistry.chemical_compound, Drug Discovery, lcsh:QH301-705.5, Pharmacology, Toxicology and Pharmaceutics (miscellaneous), Cytoskeleton, Glucose metabolism, Cell Death, Oxocins, apoptosis, cytoskeleton, 3. Good health, Second messenger system, Dinoflagellida, Cellular death, Yessotoxin, signal transduction, Intracellular, autophagy, glucose metabolism, Mollusk Venoms, Biology, 03 medical and health sciences, Immune system, Yessotoxin (YTX), Autophagy, medicine, Animals, Humans, Shellfish, 030102 biochemistry & molecular biology, Toxin, immune system, 030104 developmental biology, lcsh:Biology (General), chemistry, yessotoxin (YTX), Alzheimer |
| الوصف: | Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications The research leading to these results has received funding from the following FEDER cofunded grants. From CDTI and Technological Funds, supported by Ministerio de Economía y Competitividad, AGL2012-40185-CO2-01, AGL2014-58210-R; Consellería de Cultura, Educación e Ordenación Universitaria, GRC2013-016; CDTI under ISIP Programme, Spain, IDI-20130304 APTAFOOD; and the European Union’s Seventh Framework Programme managed by REA—Research Executive Agency (FP7/2007–2013) under grant agreement 312184 PHARMASEA SI |
| وصف الملف: | application/pdf |
| تدمد: | 1660-3397 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c96a307142be819c2fcd04075460c5aTest https://doi.org/10.3390/md14020030Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....3c96a307142be819c2fcd04075460c5a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16603397 |
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