Increased Progastrin-Releasing Peptide Expression is Associated with Progression in Gastric Cancer Patients
| العنوان: | Increased Progastrin-Releasing Peptide Expression is Associated with Progression in Gastric Cancer Patients |
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| المؤلفون: | Li Li, Juan-Yu Hu, Jian-Yong Xu, Hai Meng, Zhengqing Yu, Xiaodong Yin |
| المصدر: | Yonsei Medical Journal |
| بيانات النشر: | Yonsei University College of Medicine, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Progastrin-releasing peptide, 030204 cardiovascular system & hematology, GPI-Linked Proteins, Gastroenterology, Sensitivity and Specificity, 03 medical and health sciences, 0302 clinical medicine, Carcinoembryonic antigen, Stomach Neoplasms, Internal medicine, medicine, Biomarkers, Tumor, Humans, In patient, Antigens, Tumor-Associated, Carbohydrate, Stage (cooking), Peptide expression, Tumor node metastasis, Aged, Chemotherapy, biology, Receiver operating characteristic, business.industry, gastric cancer, Cancer, General Medicine, Middle Aged, medicine.disease, Prognosis, Peptide Fragments, Recombinant Proteins, Carcinoembryonic Antigen, Oncology, ROC Curve, 030220 oncology & carcinogenesis, Case-Control Studies, biology.protein, Disease Progression, Original Article, Female, progression, business |
| الوصف: | PURPOSE The purpose of this study was to assess the diagnostic and prognostic value of serum progastrin-releasing peptide (ProGRP) in patients with gastric cancer (GC). MATERIALS AND METHODS A total of 150 patients with GC (89 males and 61 females) were recruited, including those with stage I (n=28), stage II (n=33), stage III (n=50), and stage IV (n=39) disease; 50 healthy controls and 66 patients with benign gastric diseases were also enrolled. Levels of serum ProGRP, carcinoembryonic antigen (CEA), and carbohydrate antigen 72-4 (CA72-4) were measured in all subjects. RESULTS Serum ProGRP levels were significantly higher in GC patients than in controls (p |
| اللغة: | English |
| تدمد: | 1976-2437 0513-5796 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb50c3e5a337466e778178576a5340bTest http://europepmc.org/articles/PMC6938777Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bfb50c3e5a337466e778178576a5340b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19762437 05135796 |
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