Leukocyte Filtration Improves Pulmonary Function and Reduces the Need for Postoperative Non-Invasive Ventilation
| العنوان: | Leukocyte Filtration Improves Pulmonary Function and Reduces the Need for Postoperative Non-Invasive Ventilation |
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| المؤلفون: | Roberto Marsico, Daniela Foti, Elio Gulletta, Giuseppe Filiberto Serraino, Antonino S. Rubino, Attilio Renzulli, Valeria Ventura |
| المساهمون: | Rubino, A, Serraino Giuseppe, F., Marsico, Roberto, Ventura, Valeria, Foti, Daniela, Gulletta, Elio, Renzulli, Attilio |
| المصدر: | The International Journal of Artificial Organs. 35:679-688 |
| بيانات النشر: | SAGE Publications, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, 030204 cardiovascular system & hematology, Pulmonary function testing, law.invention, Biomaterials, 03 medical and health sciences, 0302 clinical medicine, law, Intensive care, medicine, Cardiopulmonary bypass, Humans, Platelet, Respiratory function, Hospital Mortality, Postoperative Period, Lung, Aged, Cardiopulmonary Bypass, Noninvasive Ventilation, business.industry, Incidence (epidemiology), General Medicine, Length of Stay, Middle Aged, medicine.disease, Surgery, Pneumonia, 030228 respiratory system, Anesthesia, Breathing, Cytokines, Female, Leukocyte Reduction Procedures, business |
| الوصف: | OBJECTIVES: Leukocyte depletion (LD) has been reported to reduce inflammatory damage during cardiopulmonary bypass (CPB). We evaluated the role of LD in pulmonary function and inflammatory response. METHODS: Seventy consecutive CABG patients were randomized (1:1) to receive LD on both arterial and cardioplegia lines (Filters) or standard arterial filters (Controls) during CPB. Estimates of pulmonary function, inflammatory and anti-inflammatory cytokines were collected pre-, intra- and postoperatively. RESULTS: Hospital mortality, intensive care and in-hospital lengths of stay were similar. Although duration of ventilation and incidence of pneumonia were comparable, leukodepleted patients showed higher PaO2/FiO2 (p-between groups = 0.005; ICU arrival p = 0.023; 24 hours p = 0.039; 48 hours p |
| تدمد: | 1724-6040 0391-3988 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e5bca067cbd7c88ba009e2dc558d72Test https://doi.org/10.1177/039139881203500908Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....07e5bca067cbd7c88ba009e2dc558d72 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17246040 03913988 |
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