An Aniline-Mediated Regioselective Synthesis of Quinoxalin-2-ones via the Condensation of α-Ketimine Esters with 2-Aminoanilines
| العنوان: | An Aniline-Mediated Regioselective Synthesis of Quinoxalin-2-ones via the Condensation of α-Ketimine Esters with 2-Aminoanilines |
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| المؤلفون: | Xiaoming Liao, Huy V. Huynh, Trevor J. Rainey, Teague M. McGinitie, Lizhi Yu, Selcuk Calimsiz, Hilaire V. Kemami Wangun |
| المصدر: | Synthesis. 50:2221-2230 |
| بيانات النشر: | Georg Thieme Verlag KG, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 010405 organic chemistry, Organic Chemistry, Condensation, One-pot synthesis, Regioselectivity, Substrate (chemistry), 010402 general chemistry, 01 natural sciences, Medicinal chemistry, Catalysis, 0104 chemical sciences, chemistry.chemical_compound, Aniline, chemistry |
| الوصف: | A highly regioselective method for the condensation of α-ketimine esters with 2-aminoanilines for the construction of quinoxalin-2-one derivatives is described. The substrate scope with 2-aminoaniline derivatives and different α-keto esters is explored with yields ranging from 44 to 90% and typical isolated regioselectivities between 6.4 to >25:1. |
| تدمد: | 1437-210X 0039-7881 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::bd651950003bc3796844d69bbc698f78Test https://doi.org/10.1055/s-0037-1609345Test |
| رقم الانضمام: | edsair.doi...........bd651950003bc3796844d69bbc698f78 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1437210X 00397881 |
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