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المؤلفون: Valeria Napolitano, Piotr Mróz, Monika Marciniak, Vishal C. Kalel, Charlotte A. Softley, Julian D. Janna Olmos, Bettina G. Tippler, Kenji Schorpp, Sarah Rioton, Tony Fröhlich, Oliver Plettenburg, Kamyar Hadian, Ralf Erdmann, Michael Sattler, Grzegorz M. Popowicz, Maciej Dawidowski, Grzegorz Dubin
المصدر: Eur. J. Med. Chem. 243:114778 (2022)
مصطلحات موضوعية: Pharmacology, Protein Transport, Trypanosoma, Structure-Activity Relationship, Organic Chemistry, Drug Discovery, Trypanosoma brucei brucei, Membrane Proteins, Chagas Disease, Glycosomal Protein Import, Hts, Human African Trypanosomiasis, Ppi Inhibition, Structure-based Drug Design, General Medicine, Microbodies, Trypanocidal Agents
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e15a3ec07e102366e8fc4ca9cc1dcdTest
https://pubmed.ncbi.nlm.nih.gov/36194937Test -
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المؤلفون: U. Helena Danielson, Helena Nordström, Tom Dzus, Valeria Napolitano, Giulia Opassi, Gerhard Klebe, Arne Lundin, Francesca Magari
المصدر: Protein Science
Protein Science : A Publication of the Protein Societyمصطلحات موضوعية: Chagas disease, Thermal shift assay, Trypanosoma cruzi, Fragment-based lead discovery, Farnesyl pyrophosphate, SPR, Biochemistry, Pyrophosphate, Catalysis, Article, Cofactor, 03 medical and health sciences, chemistry.chemical_compound, Magnesium, Luciferase, Molecular Biology, 030304 developmental biology, 0303 health sciences, biology, 030302 biochemistry & molecular biology, Biochemistry and Molecular Biology, Geranyltranstransferase, fragment screening, Articles, Surface Plasmon Resonance, binding efficiency, biology.organism_classification, farnesyl pyrophosphate synthase, chemistry, biology.protein, Target protein, Biokemi och molekylärbiologi
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4244925221396853671363436167464eTest
https://doi.org/10.1002/pro.3834Test -
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المؤلفون: Ekaterina L. Ratkova, Igor V. Tetko, Michael Sattler, Grzegorz Dubin, Valeria Napolitano, Roberto Fino, Maciej Dawidowski, Grzegorz M. Popowicz, Michael Sebastian Ostertag
المصدر: Chem. Commun. 56, 4360-4363 (2020)
Chemical Communicationsمصطلحات موضوعية: Pyrrolidines, Peroxisome-Targeting Signal 1 Receptor, In silico, Trypanosoma brucei brucei, Protozoan Proteins, Crystallography, X-Ray, Proof of Concept Study, 01 natural sciences, Catalysis, Protein–protein interaction, Structure-Activity Relationship, 03 medical and health sciences, Materials Chemistry, Humans, Computer Simulation, 030304 developmental biology, Envelope (waves), 0303 health sciences, Molecular Structure, 010405 organic chemistry, Chemistry, Metals and Alloys, Membrane Proteins, Water, General Chemistry, Orders of magnitude (mass), ddc, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Ceramics and Composites, Biophysics, Pyrazoles, Protein Multimerization, Protein Binding
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40869e66bf8d308bf2c99b2ca1f76db3Test
https://doi.org/10.1039/c9cc07714fTest -
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المؤلفون: Maciej, Dawidowski, Vishal C, Kalel, Valeria, Napolitano, Roberto, Fino, Kenji, Schorpp, Leonidas, Emmanouilidis, Dominik, Lenhart, Michael, Ostertag, Marcel, Kaiser, Marta, Kolonko, Bettina, Tippler, Wolfgang, Schliebs, Grzegorz, Dubin, Pascal, Mäser, Igor V, Tetko, Kamyar, Hadian, Oliver, Plettenburg, Ralf, Erdmann, Michael, Sattler, Grzegorz M, Popowicz
المصدر: Journal of medicinal chemistry. 63(2)
مصطلحات موضوعية: Models, Molecular, Trypanosoma brucei rhodesiense, Magnetic Resonance Spectroscopy, Pyridines, Trypanosoma brucei gambiense, Protozoan Proteins, Membrane Proteins, Molecular Dynamics Simulation, Crystallography, X-Ray, Trypanocidal Agents, Rats, Molecular Docking Simulation, Myoblasts, Structure-Activity Relationship, Drug Design, Animals, Humans
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::05cbdd96ae09ed23812b416f65bca487Test
https://pubmed.ncbi.nlm.nih.gov/31860309Test -
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المؤلفون: Carlo Andrea Mattia, Valeria Napolitano, Luigi Petraccone, V. A. Spiridonova, Romualdo Troisi, Irene Russo Krauss, Filomena Sica
المساهمون: Russo Krauss, Irene, Napolitano, Valeria, Petraccone, Luigi, Troisi, Romualdo, Spiridonova, Vera, Mattia, Carlo Andrea, Sica, Filomena
المصدر: International journal of biological macromolecules. 107
مصطلحات موضوعية: 0301 basic medicine, Circular dichroism, Aptamer, Duplex/quadruplex, Ultraviolet Rays, Oligonucleotides, Monovalent cation, 010402 general chemistry, G-quadruplex, Nucleic Acid Denaturation, 01 natural sciences, Biochemistry, TBA, Antithrombins, 03 medical and health sciences, chemistry.chemical_compound, Structural Biology, heterocyclic compounds, Molecular Biology, Coagulation, Base Sequence, Calorimetry, Differential Scanning, Oligonucleotide, Circular Dichroism, Bimodular aptamer, Structure-function relationship, Thrombin, Temperature, DNA, General Medicine, Aptamers, Nucleotide, 0104 chemical sciences, G-Quadruplexes, 030104 developmental biology, chemistry, Structural biology, Duplex (building), Biophysics, Anti-thrombin aptamers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92eb0653bd0b2e0104b126c95f5539bcTest
https://pubmed.ncbi.nlm.nih.gov/29024684Test -
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المساهمون: RUSSO KRAUSS, Irene, Vera, Spiridonova, Pica, Andrea, Napolitano, Valeria, Sica, Filomena
المصدر: Nucleic Acids Research
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Aptamer, Biology, Bioinformatics, G-quadruplex, Crystallography, X-Ray, Thrombin, apamer ,auplex/quadruplex, junction, anticoagulan sctivity, crystal structure, 03 medical and health sciences, Thrombin, Structural Biology, Hydrolase, Genetics, medicine, heterocyclic compounds, Hydrogen bond, Oligonucleotide, Hydrogen Bonding, Aptamers, Nucleotide, G-Quadruplexes, 030104 developmental biology, Duplex (building), Biophysics, Nucleic Acid Conformation, Corrigendum, Anti-thrombin aptamers, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08d8c07af166d65d2fbecdbf9b2a50cTest
https://pubmed.ncbi.nlm.nih.gov/31095328Test -
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المصدر: Nucleic Acids Research. 44:3969-3969
مصطلحات موضوعية: Genetics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7086d5960158af6ac2387c03f4a9666bTest
https://doi.org/10.1093/nar/gkw078Test