Quantitative analysis of internal components of the human crystalline lens during accommodation in adults
| العنوان: | Quantitative analysis of internal components of the human crystalline lens during accommodation in adults |
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| المؤلفون: | Jinming Guo, Qiongfang Xu, Wei Chen, Ting Fu, Ping Wang, Anne Manyande, Hong Zhang, Zhiqi Chen, Xuebi Tian, Junming Wang, Yan Xiang, Chaohua Deng |
| المصدر: | Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021) Scientific Reports |
| بيانات النشر: | Nature Portfolio, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, clinical_medicine, Science, Posterior parietal cortex, 01 natural sciences, Article, 010309 optics, 03 medical and health sciences, 0302 clinical medicine, Ophthalmology, Cortex (anatomy), 0103 physical sciences, Lens, Crystalline, medicine, Image Processing, Computer-Assisted, Humans, Multidisciplinary, Lenticular nucleus, business.industry, Age Factors, Accommodation, Ocular, health, clinical-care, Healthy Volunteers, eye diseases, medicine.anatomical_structure, Preclinical research, Lens (anatomy), Anterior cortex, 030221 ophthalmology & optometry, Vertex (curve), Medicine, sense organs, Anatomy, business, Nucleus, Accommodation, Tomography, Optical Coherence |
| الوصف: | Objectives. To quantitatively analyze changes in the inner components of the human crystalline lens during accommodation in adults. \ud Methods. Eyes of 23 subjects were sequentially examined using CASIA2 Optical Coherence Tomography under 0D, -3D and -6D accommodation states. The anterior chamber depth (ACD), anterior and posterior crystalline lens radius of the curvature (ALRC and PLRC) were obtained using built-in software. The lens thickness (LT), lenticular nucleus thickness (NT), anterior cortex thickness (ACT), posterior cortex thickness (PCT), anterior and posterior lenticular nucleus radius of the curvature (ANRC and PNRC), anterior and posterior lenticular nucleus vertex (ANV and PNV) were quantified manually with the Image-pro plus software.\ud Results. During accommodation, the ACD became significantly shallower and LT significantly increased. For changes in the lens, the ALRC decreased by an average magnitude （related to accommodative stimuli） 0.44 mm/D and PLRC decreased 0.09 mm/D. There was no difference for the ACT and PCT in different accommodation states. For lenticular nucleus response, NT increased on average by 30μm/D. Both the ANRC and PNRC decreased on average by 212 μm/D and 115 μm/D respectively. The ANV moved forward on average by 0.07mm under -3D accommodative stimuli and 0.16mm for -6D. However, there was no statistically significant difference between different accommodation states in the PNV movement.\ud Conclusion. Under accommodation stimulation, lens thickness changed mainly due to the lenticular nucleus, but not the cortex. For the lenticular nucleus, both the ANRC and PNRC decreased and ANRC changed the most. The anterior surface of the nucleus moved forward while the posterior surface of the nucleus moved backward but only slightly.\ud Keywords: crystalline lens, lenticular nucleus, lenticular cortex, accommodation |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2045-2322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c3b50ba1021fbd6106a5388b0ca911Test https://doaj.org/article/53835e4e1173458aab6a3431d62dfe90Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....34c3b50ba1021fbd6106a5388b0ca911 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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