نتائج البحث

1

Functional Analysis of the SIM1 Variant p.G715V in 2 Patients With Obesity

المؤلفون: Jay A. van Gerpen, Kimberly G. Harris, Owen A. Ross, Mieke M. van Haelst, Thomas R. Caulfield, Paldeep S. Atwal, Murray L. Whitelaw, Patrick R. Blackburn, Adrienne E. Sullivan, Mellody I. Cooiman, Eric W. Klee, Klaas J. Wierenga, David C. Bersten, Alexis G. Gerassimou, Lotte Kleinendorst

المساهمون: Human Genetics, Graduate School, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam Reproduction & Development (AR&D), Human genetics, Amsterdam Neuroscience - Complex Trait Genetics

المصدر: Blackburn, P R, Sullivan, A E, Gerassimou, A G, Kleinendorst, L, Bersten, D C, Cooiman, M, Harris, K G, Wierenga, K J, Klee, E W, van Gerpen, J A, Ross, O A, van Haelst, M M, Whitelaw, M L, Caulfield, T R & Atwal, P S 2020, ' Functional Analysis of the SIM1 Variant p.G715V in 2 Patients With Obesity ', The Journal of clinical endocrinology and metabolism, vol. 105, no. 1, pp. 1-7 . https://doi.org/10.1210/clinem/dgz192Test
Journal of clinical endocrinology and metabolism, 105(1), 1-7. The Endocrine Society
The Journal of clinical endocrinology and metabolism, 105(1), 1-7. The Endocrine Society

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Aryl hydrocarbon receptor nuclear translocator, Endocrinology, Diabetes and Metabolism, Two-hybrid screening, Clinical Biochemistry, Mutation, Missense, Glutamic Acid, 030105 genetics & heredity, Biology, Biochemistry, 03 medical and health sciences, Endocrinology, Single-minded homolog 1, Internal medicine, medicine, Basic Helix-Loop-Helix Transcription Factors, Missense mutation, Humans, Obesity, SIM1, Genetic Association Studies, P.G715V, Genetics, Biochemistry (medical), Valine, Middle Aged, Penetrance, Phenotype, Repressor Proteins, 030104 developmental biology, Amino Acid Substitution, CHD2, Prader-Willi-like syndrome, Haploinsufficiency, Prader-Willi Syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c212a6cf4759487d4bbc82f6d37d120fTest
https://doi.org/10.1210/clinem/dgz192Test

2

Colonic Lactulose Fermentation Has No Impact on Glucagon-like Peptide-1 and Peptide-YY Secretion in Healthy Young Men

المؤلفون: Søren Møller, Bolette Hartmann, Astrid Marie Gauguin, C. Christiansen, Jens J. Holst, Simon Veedfald, Thomas Moritz, Sten Madsbad

المصدر: The Journal of clinical endocrinology and metabolism. 107(1)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Colon, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Administration, Oral, Context (language use), Gut flora, Biochemistry, 03 medical and health sciences, Lactulose, Young Adult, 0302 clinical medicine, Endocrinology, Glucagon-Like Peptide 1, Internal medicine, medicine, Humans, Peptide YY, Intestinal Mucosa, 030304 developmental biology, 0303 health sciences, Cross-Over Studies, biology, Chemistry, Biochemistry (medical), Peptide secretion, biology.organism_classification, Glucagon-like peptide-1, Healthy Volunteers, Gastrointestinal Microbiome, Postprandial, Fermentation, 030211 gastroenterology & hepatology, medicine.drug, Hormone

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f04c62a7513feea9664bd66971d6a0Test
https://pubmed.ncbi.nlm.nih.gov/34508600Test

3

PD-1 and PD-L1 Expression in Peripheral CD4/CD8+ T Cells Is Restored in the Partial Remission Phase in Type 1 Diabetes

المؤلفون: Zhiguang Zhou, Fang Liu, Ting Zhong, Xia Li, Yuting Xie, Chao Wu, Rong Tang

المصدر: The Journal of clinical endocrinology and metabolism. 105(6)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, CD4-Positive T-Lymphocytes, Male, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Programmed Cell Death 1 Receptor, CD8-Positive T-Lymphocytes, Biochemistry, T-Lymphocytes, Regulatory, B7-H1 Antigen, 0302 clinical medicine, Endocrinology, Cytotoxic T cell, Prospective Studies, Child, biology, Chemistry, Remission Induction, Middle Aged, Prognosis, Child, Preschool, Female, Adult, medicine.medical_specialty, Adolescent, 030209 endocrinology & metabolism, Context (language use), 03 medical and health sciences, Young Adult, Immune system, Downregulation and upregulation, Internal medicine, PD-L1, medicine, Humans, Aged, Glycated Hemoglobin, Type 1 diabetes, Biochemistry (medical), Infant, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Case-Control Studies, biology.protein, Hemoglobin, CD8, Biomarkers, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d699b5dedc204397be237eefc4fba29Test
https://pubmed.ncbi.nlm.nih.gov/32236416Test

4

HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes

المؤلفون: Christoph Engel, Nora Klöting, Michael Stumvoll, Joachim Thiery, Lucas Massier, Peter Kovacs, Katrin Horn, Thomas Jacobi, Markus Scholz, Ilias Doxiadis, Anke Tönjes, Matthias Blüher, Peter Ahnert, Alexander Schuch, Ralph Burkhardt, Markus Löffler

المصدر: The Journal of clinical endocrinology and metabolism. 105(3)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, DNA Mutational Analysis, Genes, MHC Class II, 030209 endocrinology & metabolism, Single-nucleotide polymorphism, Type 2 diabetes, Human leukocyte antigen, Biology, Biochemistry, Polymorphism, Single Nucleotide, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Gene Frequency, Diabetes mellitus, Internal medicine, Germany, medicine, Genetic predisposition, Humans, Genetic Predisposition to Disease, Allele, Genetic Association Studies, Aged, Genetics, Type 1 diabetes, Biochemistry (medical), Haplotype, Middle Aged, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Haplotypes, Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458568e2b4f9cb54b9243720ca84054aTest
https://pubmed.ncbi.nlm.nih.gov/31974565Test

5

Genome-Wide Association for HbA1c in Malay Identified Deletion on SLC4A1 that Influences HbA1c Independent of Glycemia

المؤلفون: Shih-Ling Kao, Victor Jun Yu Lim, Sonia Chothani, Jianjun Liu, Jinzhuang Dou, Ching-Yu Cheng, Xueling Sim, Charumathi Sabanayagam, Andrew D. Paterson, Chaolong Wang, Rob M. van Dam, Jin-Fang Chai, Dermot F. Reilly, Tien Yin Wong, Ing Wei Khor, Anna I. Podgornaia

المصدر: The Journal of clinical endocrinology and metabolism. 105(12)

مصطلحات موضوعية: 0301 basic medicine, Adult, Blood Glucose, Male, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, 030209 endocrinology & metabolism, Locus (genetics), Genome-wide association study, Biology, Biochemistry, Cohort Studies, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Endocrinology, Asian People, Internal medicine, Anion Exchange Protein 1, Erythrocyte, medicine, Ethnicity, Humans, Prediabetes, 1000 Genomes Project, Exome, Malay, Genetic association, Aged, Genetics, Glycated Hemoglobin, Singapore, Polymorphism, Genetic, Biochemistry (medical), Elliptocytosis, Hereditary, Malaysia, Middle Aged, medicine.disease, language.human_language, 030104 developmental biology, Cross-Sectional Studies, Case-Control Studies, language, Female, Imputation (genetics), Gene Deletion, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084b88118dd15e7dafda8934e9d5b045Test
https://pubmed.ncbi.nlm.nih.gov/32936915Test

6

Immune Co-inhibitory Receptors PD-1, CTLA-4, TIM-3, LAG-3, and TIGIT in Medullary Thyroid Cancers: A Large Cohort Study

المؤلفون: Wen-Jun Wei, Cui-Wei Li, Li-Cheng Tan, Xiao Shi, Ning Qu, Tong-Zhen Chen, Yu-Long Wang, Peng-Cheng Yu, Qinghai Ji, Tian Liao, Shishuai Wen, Yu Wang, Rong-Liang Shi, Ben Ma, Yan Zhang, Zhongwu Lu

المصدر: The Journal of clinical endocrinology and metabolism. 106(1)

مصطلحات موضوعية: Oncology, Male, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Clinical Biochemistry, Programmed Cell Death 1 Receptor, Biochemistry, Cohort Studies, Endocrinology, Medicine, CTLA-4 Antigen, Receptors, Immunologic, Child, Hepatitis A Virus Cellular Receptor 2, Aged, 80 and over, Tissue microarray, biology, Middle Aged, Prognosis, Immunohistochemistry, Lymphocyte Activation Gene 3 Protein, Disease Progression, Female, Antibody, Adult, medicine.medical_specialty, China, Adolescent, Context (language use), Young Adult, TIGIT, Antigen, Antigens, CD, PD-L1, Internal medicine, Biomarkers, Tumor, Humans, Thyroid Neoplasms, Aged, Retrospective Studies, business.industry, Biochemistry (medical), Immunotherapy, Immune Checkpoint Proteins, Survival Analysis, Carcinoma, Neuroendocrine, CTLA-4, Tissue Array Analysis, biology.protein, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564eb5f9ccfb87a2d235499e0211c3d1Test
https://pubmed.ncbi.nlm.nih.gov/33000173Test

7

Genetic Variation at PPP1R3B Increases Hepatic CT Attenuation and Interacts With Prandial Status on Plasma Glucose

المؤلفون: Anne-Sofie Seidelin, Stefan Stender, Børge G. Nordestgaard, Anne Tybjærg-Hansen

المصدر: The Journal of clinical endocrinology and metabolism. 105(6)

مصطلحات موضوعية: 0301 basic medicine, Adult, Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Population, Context (language use), 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Endocrinology, Internal medicine, Hounsfield scale, Protein Phosphatase 1, medicine, Humans, Prospective Studies, education, Aged, Aged, 80 and over, Meal, education.field_of_study, biology, Glycogen, business.industry, Tomography, X-Ray, Liver Diseases, Biochemistry (medical), Genetic Variation, Fasting, Middle Aged, Postprandial Period, Prognosis, 030104 developmental biology, Postprandial, Alanine transaminase, chemistry, biology.protein, Population study, Female, business, Biomarkers, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de25583a58b6ef42b529ed007d6d2e06Test
https://pubmed.ncbi.nlm.nih.gov/32219298Test

8

Contribution of Liver Fat to Weight Loss-Induced Changes in Serum Hepatokines: A Randomized Controlled Trial

المؤلفون: Nicolaas C. Schaper, Peter J. Joris, Martijn C. G. J. Brouwers, Jogchum Plat, Casper G. Schalkwijk, Ine Telgenkamp, Ronald P. Mensink, Yvo H.A.M. Kusters, Coen D.A. Stehouwer, Judith A P Bons, Lucas Lindeboom, M. Eline Kooi, Alfons J.H.M. Houben

المساهمون: RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation, RS: CARIM - R3.01 - Vascular complications of diabetes and the metabolic syndrome, Promovendi PHPC, RS: Carim - V01 Vascular complications of diabetes and metabolic syndrome, Promovendi CD, MUMC+: MA Med Staf Artsass Interne Geneeskunde (9), Interne Geneeskunde, RS: CARIM - R3 - Vascular biology, RS: Carim - B06 Imaging, Beeldvorming, MUMC+: DA BV Klinisch Fysicus (9), RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, RS: CARIM - R3.11 - Imaging, Nutrition and Movement Sciences, MUMC+: DA CDL Algemeen (9), RS: NUTRIM - R3 - Respiratory & Age-related Health, MUMC+: MA Endocrinologie (9), RS: CARIM - R3.02 - Hypertension and target organ damage, MUMC+: MA Interne Geneeskunde (3), MUMC+: MA Maag Darm Lever (9), MUMC+: MA Hematologie (9), MUMC+: MA Medische Oncologie (9), MUMC+: MA Nefrologie (9), MUMC+: HVC Pieken Maastricht Studie (9), MUMC+: MA Reumatologie (9)

المصدر: Journal of Clinical Endocrinology & Metabolism, 104(7), 2719-2727. Oxford University Press

مصطلحات موضوعية: 0301 basic medicine, Male, alpha-2-HS-Glycoprotein, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Type 2 diabetes, Biochemistry, FGF21, 0302 clinical medicine, Endocrinology, Sex hormone-binding globulin, Weight loss, Sex Hormone-Binding Globulin, CALORIE RESTRICTION, Medicine, FETUIN-A, Insulin-Like Growth Factor I, Abdominal obesity, RISK, biology, Middle Aged, Liver, LIFE-STYLE INTERVENTION, OBESITY, Obesity, Abdominal, GROWTH-HORMONE, medicine.symptom, Adult, medicine.medical_specialty, Diet, Reducing, 030209 endocrinology & metabolism, Context (language use), 03 medical and health sciences, Internal medicine, Weight Loss, Humans, HEPATIC STEATOSIS, Triglycerides, OVERWEIGHT, business.industry, Biochemistry (medical), Case-control study, medicine.disease, Obesity, Fetuin, CIRCULATING LEVELS, Fetuin-B, Fibroblast Growth Factors, Insulin-Like Growth Factor Binding Protein 1, 030104 developmental biology, Cross-Sectional Studies, Case-Control Studies, biology.protein, business