JAK2 mutation and disease phenotype: a double L611V/V617F in cis mutation of JAK2 is associated with isolated erythrocytosis and increased activation of AKT and ERK1/2 rather than STAT5
العنوان: | JAK2 mutation and disease phenotype: a double L611V/V617F in cis mutation of JAK2 is associated with isolated erythrocytosis and increased activation of AKT and ERK1/2 rather than STAT5 |
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المؤلفون: | Sylvie Hermouet, Harousseau Jl, Marjorie Boissinot, J.-P. Issa, Ponge T, Jaroslav Jelinek, Cédric Cleyrat, François Girodon |
المصدر: | Leukemia. 24:1069-1073 |
بيانات النشر: | Springer Science and Business Media LLC, 2010. |
سنة النشر: | 2010 |
مصطلحات موضوعية: | Cancer Research, Janus kinase 2, biology, food and beverages, Hematology, Phenotype, Molecular biology, Myeloproliferative Disorders, Oncology, hemic and lymphatic diseases, Genotype, Mutation (genetic algorithm), biology.protein, Phosphorylation, Protein kinase B, hormones, hormone substitutes, and hormone antagonists, STAT5 |
الوصف: | JAK2 mutation and disease phenotype: a double L611V/V617F in cis mutation of JAK2 is associated with isolated erythrocytosis and increased activation of AKT and ERK1/2 rather than STAT5 |
تدمد: | 1476-5551 0887-6924 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::99f43ae8abdb267ec309fbfacbe16839Test https://doi.org/10.1038/leu.2010.23Test |
حقوق: | OPEN |
رقم الانضمام: | edsair.doi...........99f43ae8abdb267ec309fbfacbe16839 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 14765551 08876924 |
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