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المؤلفون: Vittorio Krogh, Rudolf Kaaks, Yvonne T. van der Schouw, Gianluca Severi, Eva Ardanaz, Marc J. Gunter, Tilman Kühn, Nicholas J. Wareham, Timothy J. Key, Francesca Mancini, Carlotta Sacerdote, María José Sánchez, Heiner Boeing, Annemieke M.W. Spijkerman, Peter M. Nilsson, Guy Fagherazzi, Miren Dorronsoro, María Dolores Chirlaque, Kay-Tee Khaw, Olov Rolandsson, Stephen J. Sharp, Salvatore Panico, Domenico Palli, Nita G. Forouhi, Christiane S. Hampe, Claudia Langenberg, Kim Overvad, Rosario Tumino, Elio Riboli
المساهمون: Centre de recherche en épidémiologie et santé des populations (CESP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), LSHM_CT_2006_037197 N∫ 6236 National Institutes of Health, NIH: DK26190 Compagnia di San Paolo Kræftens Bekæmpelse, DCS German Cancer Research Center, DKFZ Medical Research Council, MRC: MC_UU_12015/1, MC_UU_12015/5, MR/N003284/1 Cancer Research UK, CRUK World Cancer Research Fund, WCRF Bundesministerium für Bildung und Forschung, BMBF Västerbotten Läns Landsting Ministerie van Volksgezondheid, Welzijn en Sport, VWS Agentschap NL: IGE05012 Vetenskapsrådet, VR Umeå Universitet Bundesministerium für Forschung und Technologie, BMFT Deutsche Krebshilfe Bundesministerium für Bildung und Frauen, BMBF Stichting Diabetes Onderzoek Nederland NIHR Imperial Biomedical Research Centre, BRC NIHR Cambridge Biomedical Research Centre: IS-BRC-1215-20014, O. Rolandsson: The Västerboten County Council, M. Dorronsoro: We thank the participants of the Spanish EPIC cohort for their contribution to the study as well as to the team of trained nurses who participated in the recruitment, R. Kaaks: German Cancer Aid, German Ministry of Research (BMBF), K. T. Khaw: Medical Research Council UK, Cancer Research UK, T. Kühn: German Cancer Aid, German Cancer Research Center (DKFZ), German Federal Ministry of Education and Research (BMBF), S. Panico: Compagnia di San Paolo, A. M. W. Spijkerman: EPIC Bilthoven and Utrecht acknowledge the Dutch Ministry of Public Health, Welfare and Sports (VWS), Netherlands Cancer Registry (NKR), Statistics Netherlands (the Netherlands), EPIC Ragusa acknowledges for their participation blood donors of AVIS-Ragusa (local blood donors association), Y. T. van der Schouw: EPIC Bilthoven and Utrecht acknowledge the Dutch Ministry of Public Health, Welfare and Sports (VWS), Netherlands Cancer Registry (NKR), Dutch ZON (Zorg Onderzoek Nederland), WCRF, Statistics Netherland, E. Riboli: Imperial College Biomedical Research Centre., Open access funding provided by Umea University. Funding for the InterAct project was provided by the EU FP6 Programme (grant number LSHM_CT_2006_037197). The autoantibody measurement was funded by Västerbotten County Council and Umeå University, Sweden (OR), the National Institutes of Health (DK26190) (CSH) and the Medical Research Council (MC_UU_12015/1) (NJW). OR: the Västerbotten County Council, Umeå University, MDC: Health Research Fund (FIS) of the Spanish Ministry of Health, Murcia Regional Government (N∫ 6236), EA: the Health Research Fund (FIS) of the Spanish Ministry of Health and Navarre Regional Government, RK: German Cancer Aid, the German Ministry of Research (BMBF), TJK: Cancer Research UK, KTK: the Medical Research Council UK, Cancer Research UK, PMN: the Swedish Research Council, KO: the Danish Cancer Society, SP: Compagnia di San Paolo, AMWS: the Dutch Ministry of Public Health, Welfare and Sports (VWS), the Netherlands Cancer Registry (NKR), LK Research Funds, Dutch Prevention Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), Statistics Netherlands, RT: AIRE-ONLUS Ragusa, AVIS-Ragusa, Sicilian Regional Government, AMWS: LK Research Funds, Dutch Prevention Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund (WCRF), YTvdS: verification of diabetes cases was additionally funded by NL Agency grant IGE05012 and an Incentive Grant from the Board of the UMC Utrecht, LK Research Funds, Dutch Prevention Funds, NGF: MRC core support (MC_UU_12015/5), NIHR Cambridge Biomedical Research Centre (IS-BRC-1215-20014). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. Acknowledgements, We thank all EPIC participants and staff for their contribution to this study. We thank N. Kerrison (MRC Epidemiology Unit, Cambridge, UK) for managing the data and the laboratory team at the MRC Epidemiology Unit, Cambridge for managing the blood samples for the EPIC-InterAct project. We thank the participants of the Spanish EPIC cohort for their contribution to the study as well as the team of trained nurses who participated in the recruitment. O. Rolandsson: The V?sterboten County Council, T. K?hn: German Cancer Aid, German Cancer Research Center (DKFZ), German Federal Ministry of Education and Research (BMBF), E. Riboli: Imperial College Biomedical Research Centre. Some of the data were presented as an abstract at the 54th EASD Annual Meeting in 2018., Rolandsson, Olov [0000-0002-1341-6828], Apollo - University of Cambridge Repository
المصدر: Rolandsson, O, Hampe, C S, Sharp, S J, Ardanaz, E, Boeing, H, Fagherazzi, G, Mancini, F R, Nilsson, P M, Overvad, K, Chirlaque, M-D, Dorronsoro, M, Gunter, M J, Kaaks, R, Key, T J, Khaw, K-T, Krogh, V, Kühn, T, Palli, D, Panico, S, Sacerdote, C, Sánchez, M-J, Severi, G, Spijkerman, A M W, Tumino, R, van der Schouw, Y T, Riboli, E, Forouhi, N G, Langenberg, C & Wareham, N J 2020, ' Autoimmunity plays a role in the onset of diabetes after 40 years of age ', Diabetologia, vol. 63, no. 2, pp. 266-277 . https://doi.org/10.1007/s00125-019-05016-3Test
Diabetologia
Diabetologia, Springer Verlag, 2020, 63 (2), pp.266-277. ⟨10.1007/s00125-019-05016-3⟩
Diabetologia, 63, 266. Springer Verlagمصطلحات موضوعية: Male, [SDV]Life Sciences [q-bio], Endocrinology, Diabetes and Metabolism, Autoimmunity, Type 2 diabetes, medicine.disease_cause, LADA, Endocrinology, Autoantibody, 0302 clinical medicine, POPULATION, RISK, 0303 health sciences, Glutamate Decarboxylase, ANTIBODY POSITIVITY, GAD, Middle Aged, Phenotype, Genetic risk score, Pathophysiology, 3. Good health, Diabetes and Metabolism, Type 1 diabetes, Endokrinologi och diabetes, Female, Life Sciences & Biomedicine, Adult, 030209 endocrinology & metabolism, Endocrinology and Diabetes, Antibodies, Article, 1117 Public Health and Health Services, Endocrinology & Metabolism, 03 medical and health sciences, GLUTAMIC-ACID DECARBOXYLASE, Insulin resistance, Diabetes mellitus, Internal Medicine, medicine, Humans, TYPE-1, Aged, 030304 developmental biology, Science & Technology, business.industry, RECOGNITION, 1103 Clinical Sciences, ADULTS, medicine.disease, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Incident diabetes, Case-Control Studies, Immunology, 1114 Paediatrics and Reproductive Medicine, AUTOANTIBODIES, indident diabetes, business
وصف الملف: application/pdf; text/xml; image/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46551c110c8a2c18bb7e24b7c5c12882Test
https://doi.org/10.1007/s00125-019-05016-3Test -
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المؤلفون: Craig A. Beam, Johnny Ludvigsson, Kevan C. Herold, Colleen MacCallum, Jerry P. Palmer, Diane K. Wherrett
المصدر: Diabetologia. 60:43-49
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Bayesian probability, 030209 endocrinology & metabolism, Placebo, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Internal Medicine, medicine, Humans, Insulin, 030212 general & internal medicine, Child, Vaccines, Type 1 diabetes, Glutamate Decarboxylase, business.industry, Bayes Theorem, Middle Aged, medicine.disease, Clinical trial, Vaccination, Diabetes Mellitus, Type 1, Meta-analysis, Immunology, Female, business, Expected loss
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c011f637d406d9cfe7e1d2407ca06478Test
https://doi.org/10.1007/s00125-016-4122Test-1 -
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المؤلفون: Riitta Veijola, Michael G. Kenward, Mikael Knip, Liisa Uusitalo, T. Korhonen, Jaakko Nevalainen, Suvi M. Virtanen, G. Alfthan, Olli Simell, Sari Niinistö, Hannu Oja, Jouko Sundvall, Jorma Ilonen
المصدر: Diabetologia. 51:773-780
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Insulin Antibodies, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, alpha-Tocopherol, Mothers, Autoimmunity, Human leukocyte antigen, medicine.disease_cause, Cohort Studies, HLA Antigens, Risk Factors, Insulin-Secreting Cells, Immunopathology, Internal medicine, Internal Medicine, medicine, Genetic predisposition, Humans, Genetic Predisposition to Disease, Risk factor, Child, Autoimmune disease, Type 1 diabetes, gamma-Tocopherol, Glutamate Decarboxylase, business.industry, Vitamin E, medicine.disease, Diabetes Mellitus, Type 1, Endocrinology, Immunology, Educational Status, Female, business, Maternal Age
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b7cf7b01da11e2132029b5d0579a72Test
https://doi.org/10.1007/s00125-008-0959-2Test -
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المؤلفون: J. Seissler, Werner A. Scherbaum, T. Lohmann, Holger Steinbrenner, B. Ostendorf
المصدر: Diabetologia. 43:1381-1384
مصطلحات موضوعية: Adult, Male, endocrine system, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Glutamate decarboxylase, Gene Expression, Autoantigens, Sensitivity and Specificity, Islets of Langerhans, Antigen, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Receptor-Like Protein Tyrosine Phosphatases, Class 8, RNA, Messenger, Cloning, Molecular, Child, Immunosorbent Techniques, Autoantibodies, Brain Chemistry, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Autoimmune disease, biology, business.industry, Insulin, High Mobility Group Proteins, Autoantibody, Infant, Membrane Proteins, Middle Aged, medicine.disease, Anti-thyroid autoantibodies, Diabetes Mellitus, Type 1, Endocrinology, Child, Preschool, Immunology, biology.protein, Female, Protein Tyrosine Phosphatases, Antibody, business, SOXD Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c24aa826e3cdda3b3e7086b3947e993Test
https://doi.org/10.1007/s001250051542Test -
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المصدر: Diabetologia. 55(5)
مصطلحات موضوعية: Adult, Male, Risk, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Glutamate decarboxylase, Zinc Transporter 8, Prediabetic State, HLA Antigens, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Prevalence, Humans, Receptor-Like Protein Tyrosine Phosphatases, Class 8, Cation Transport Proteins, Aged, Autoantibodies, Type 1 diabetes, biology, C-Peptide, business.industry, Glutamate Decarboxylase, Norway, Autoantibody, Middle Aged, medicine.disease, Phenotype, Endocrinology, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Haplotypes, Immunology, biology.protein, Etiology, Female, Antibody, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e205c2e4979ede8bc361e6432a965bTest
https://pubmed.ncbi.nlm.nih.gov/22297581Test -
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المؤلفون: D Wile, Geoffrey Gill, A. Tekle, M. Diver, Patrick English, Alistair J K Williams, Solomon Tesfaye, Ahmed Reja
المصدر: Diabetologia. 54(1)
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Disease, Type 2 diabetes, chemistry.chemical_compound, Diabetes mellitus, Internal medicine, Internal Medicine, Medicine, Humans, Insulin, Autoantibodies, Type 1 diabetes, C-Peptide, business.industry, C-peptide, Glutamate Decarboxylase, Malnutrition, Middle Aged, medicine.disease, Diabetes Mellitus, Type 1, chemistry, Diabetes Mellitus, Type 2, Cohort, Immunology, Female, Ethiopia, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81089e6090be069552816d7db93a5d2Test
https://pubmed.ncbi.nlm.nih.gov/20890591Test -
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المؤلفون: Ian R. Mackay, Paul Zev Zimmet, Merrill J. Rowley, Susan W. Serjeantson, Maija R.J. Kohonen-Corish, W. Knowles
المصدر: Diabetologia. 35:996-1001
مصطلحات موضوعية: Adult, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Glutamate decarboxylase, medicine.disease_cause, Antibodies, White People, Autoimmunity, Asian People, Japan, Antigen, HLA-DQ Antigens, Diabetes mellitus, Internal medicine, HLA-DQ, Internal Medicine, medicine, Humans, Child, Type 1 diabetes, Korea, Glutamate Decarboxylase, business.industry, Australia, Autoantibody, HLA-DR Antigens, Glutamic acid, medicine.disease, Diabetes Mellitus, Type 1, Endocrinology, Child, Preschool, Antibody Formation, Immunology, Hong Kong, business, Biomarkers, Polymorphism, Restriction Fragment Length
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0309bdac2318b2a90579d7dafe793d36Test
https://doi.org/10.1007/bf00401432Test -
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المؤلفون: Decochez, K, De Leeuw, I H, Keymeulen, B, Mathieu, C, Rottiers, R, Weets, I, Vandemeulebroucke, E, Truyen, I, Kaufman, L, Schuit, F C, Pipeleers, D G, Gorus, F K, Belgian Diabetes Registry, Beckers, Dominique
المساهمون: UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de pédiatrie, Belgian Diabetes Registry
المصدر: Diabetologia, Vol. 45, no.12, p. 1658-66 (2002)
Diabetologiaمصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Insulin Antibodies, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Risk Assessment, Gastroenterology, Predictive Value of Tests, Internal medicine, Diabetes mellitus, HLA-DQ, Internal Medicine, medicine, Humans, Longitudinal Studies, Sibling, Child, Survival analysis, Autoantibodies, Proportional Hazards Models, Glutamate Decarboxylase, Proportional hazards model, business.industry, Insulin, Infant, Newborn, Autoantibody, Infant, medicine.disease, Isoenzymes, Diabetes Mellitus, Type 1, Child, Preschool, Predictive value of tests, Immunology, Female, Human medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9d692d5d348f17c66a32cbce6e5285Test
https://doi.org/10.1007/s00125-002-0949-8Test -
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المؤلفون: J. S. Dorman, D. J. Becker, Massimo Pietropaolo, Massimo Trucco, S. Riboni, Sati Mazumdar, Ronald E. LaPorte, William A. Rudert
المصدر: Diabetologia. 45:66-76
مصطلحات موضوعية: Adult, Time Factors, Adolescent, endocrine system diseases, Insulin Antibodies, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Human leukocyte antigen, Risk Assessment, Prediabetic State, Islets of Langerhans, HLA-DQ Antigens, Diabetes mellitus, HLA-DQ, Prevalence, Internal Medicine, medicine, Humans, Registries, Allele, Child, Aged, Autoantibodies, Demography, geography, geography.geographical_feature_category, Glutamate Decarboxylase, business.industry, Insulin, Haplotype, Age Factors, Autoantibody, nutritional and metabolic diseases, Middle Aged, Pennsylvania, Islet, medicine.disease, Isoenzymes, Diabetes Mellitus, Type 1, Haplotypes, Immunology, business, Follow-Up Studies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae005b92d6f1401a2269a07326c38dbbTest
https://doi.org/10.1007/s125-002-8246-5Test -
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المؤلفون: J. Steindorf, J. Seissler, H.-J. Verlohren, Tobias Lohmann, J. Krug, K. Kellner, Werner A. Scherbaum
المصدر: Diabetologia. 44:1005-1010
مصطلحات موضوعية: Adult, Latent autoimmune diabetes of adults, Endocrinology, Diabetes and Metabolism, Glutamate decarboxylase, Autoimmune Diseases, Body Mass Index, Islets of Langerhans, Diabetes mellitus, Internal Medicine, medicine, Humans, Autoantibodies, Autoimmune disease, C-Peptide, biology, Glutamate Decarboxylase, business.industry, Autoantibody, Fasting, Middle Aged, medicine.disease, Titer, Diabetes Mellitus, Type 1, Immunology, biology.protein, Antibody, Metabolic syndrome, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334161de9a79bc33dbcc1fcdbef26c57Test
https://doi.org/10.1007/s001250100602Test