دورية أكاديمية
Polymer-based or Polymer-free Stents in Patients at High Bleeding Risk.
| العنوان: | Polymer-based or Polymer-free Stents in Patients at High Bleeding Risk. |
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| المؤلفون: | Windecker, Stephan, Latib, Azeem, Kedhi, Elvin, Kirtane, Ajay J, Kandzari, David E, Mehran, Roxana, Price, Matthew J, Abizaid, Alexandre, Simon, Daniel I, Worthley, Stephen G, Zaman, Azfar, Hudec, Martin, Poliacikova, Petra, Abdul Ghapar, A Kahar Bin, Selvaraj, Kamaraj, Petrov, Ivo, Mylotte, Darren, Pinar, Eduardo, Moreno, Raul, Fabbiocchi, Franco, Pasupati, Sanjeevan, Kim, Hyo-Soo, Aminian, Adel, Tie, Charles, Wlodarczak, Adrian, Hur, Seung-Ho, Marx, Steven O, Jankovic, Ivana, Brar, Sandeep, Bousquette, Lisa, Liu, Minglei, Stone, Gregg W, ONYX ONE |
| المساهمون: | Friedrich, Guy, Basic, Daniel, Brenner, Christoph, Dichtl, Wolfgang, Doerler, Jakob, Kirchmair, Rudolf, Klug, Gert, Mair, Johannes, Metzler, Bernhard, Moes, Nico, Plank, Fabian, Schreinlechner, Michael, Stuhlinger, Markus, Zaruba, Marc, Mayerl, Christina, Mrakovic, Anita, Mrakovic, Sarah, Petrov, Ivo, Dimitrova, Viktoria, Dobrev, Georgi, Pavlova, Silvia, Polomski, Petar, Stanillov, Plamen, Stankov, Zoran, Tasheva, Iveta, Kireva, Nadezhda, Milanova, Nadia, Petkova, Dafinka, Stancheva, Nadezhda, Zheglova, Ralitsa, Tie, Charles, Chacko, Georgy, Montarello, Joseph, Sage, Peter, Samaraie, Luay, Sidharta, Samuel, Cole, Joanna, Contibas, Michael, Deans, Renae, Fragnito, Kristen, Thring, Kate, Park, Seung Jung, Ahn, JungMin, Kang, DoYoon, Kwon, Osung, Lee, Pil Hyoung, Lee, Seung Whan, Park, Duk Woo, Jang, Soon Deok, Kim, Jong Sun, Lee, Jung Hwa, Lee, Min Suk, Webster, Mark, Ruygrok, Peter, Somaratne, Jithendra, Stewart, James, Burd, Jan, Clarke, Robin, Fish, Mandy, Conradie, Andre, Di Fiore, David, Grout, David, Wittmer, Hermann, Bryant, Lesley, Fox, Karen, Howes, Kassandra, Morgan, Jill, Nelson, Sonia, Starmer, Gregory, Brazzale, Anthony, Lam, Willis Chunwai, Ng, Kevin, Preston, Shane, Reddy, Saireddy Ramakrishna, Sutcliffe, Steven, Dixon, Sue, Gosley, Michelle, Anderson, Richard, Amtra, Rito, Choudhury, Anirban, Gallagher, Sean, Khurana, Ayush, Chandler, Kayleigh, Hodges, Elizabeth, Holder, Jacqueline, Nott, Claire, Thompson, Elizabeth, Moccetti, Tiziano, Araco, Marco, Bomio, Fulvio, Crljenica, Carmela, Del Bufalo, Alessandro, Moccetti, Marco, Monti, Cristina, Pasotti, Elena, Pedrazzini, Giovanni, Quagliana, Angelo, Rossi, Mariagrazia, Petrova Slater, Iveta, Surder, Daniel, Camporini, Cristina, Chiumiento, Lorena, Forlenza, Rossella, Maspoli, Simona, Polledri, Simona, Ponti, Giada, Serra, Anna, Fabbiocchi, Franco, Bartorelli, Antonio, Calligaris, Giuseppe, De Martini, Stefano, Galli, Stefano, Montorsi, Piero, Teruzzi, Giovanni, Trabattoni, Daniela, Jeong, Myung-Ho, Kim, Min Chul, Kim, Yong Cheol, Kim, Doo Sun Sim Yuri, Aminian, Adel, Ben Yedder, Mohamed, Dolatabadi, Dariouch, Lalmand, Jacques, Lefebvre, Pascal, Conde Y Bolado, Asuncion, El Houri, Aya, Piamonte, Veronica, Teixeira, Elisabete, LANCELLOTTI, Patrizio, DAVIN, Laurent, Gach, Olivier, LEMPEREUR, Mathieu, MARECHAL, Patrick, Christophe, Christophe, Martinez, Martinez, Dive, Anne-Francoise, Doneux, Pierre, Silvestri, Marc, Maillard, Luc, Tavildari, Alain, Sevilla, José, Shetty, Sharad, Clugston, Richard, Erickson, Matthew, Judkins, Chris, Kuppusamy, Harveen, Lee, Felicity, Mabote, Thato, Nguyen, Michael, Rankin, James, Shiekh, Imran Amin, Whelan, Alan, Yong, Gerald, Forrest, Nicole, Greenwell, Della, Tulloch, Gill, Sinhal, Ajay, Chew, Derek, Chuang, Ming-Yu, Nazir, Sheraz, Tee, Su Ling, Tiver, Kathryn, Hincks, Christine, Horsfall, Matthew, Thomas, Simeoni, Wollaston, Fiona, Mylotte, Darren, Ahmed, Khalid, Amario Bel, Xavier, Reddy Bijjam, Venu, Connolly, Niall, Crowley, Jim, Cusack, Ronan, Hynes, Brian, Ullah Jan, Zia, Keane, Stephen, MacNeill, Briain, McGrath, Brian, Nash, Patrick, Neylon, Antoinette, O'Connor, Tim, Quinn, Sandra, Rosseel, Liesbeth, Sharif, Faisal, Burke, Maura, Coen, Eileen, Duane, Linda, Finnerty, Sara, Glynn, Nicola, Ryan, Chloe, Kastberg, Robert, Hellsten, Lasse, Johansson, Staffan, Lutter, Kris, Saleh, Elena, Bergström, Kristina, Mauritzon, Marina, Oldroyd, Keith, Good, Richard, Kelly, Joanne, McLaren, Ruth, O'Donnell, Anna, Tewkesbury, Alex, Teyhan, Fiona, Wojakowski, Wojciech, Dworowy, Sebastian, Gasior, Pawel, Kurzelowski, Radosław, Nowak, Adrianna, Ochała, Andrzej, Haag, Den, Somi, Samer, Bax, Matthijs, Bleeker, Gabe, Haasdijk, Arnout, Hoftijzer, Dieke, Liu, Tommy, Schotborgh, Carl, Karijodikoro-Bogaards, Ellen, van den Heuvel, Anne-Marthe, Chevalier, Bernard, Ben-Amer, Hakim, Champagne, Stéphane, Garot, Philippe, Hovasse, Thomas, Lefevre, Thierry, Sanguineti, Francesca, Unterseeh, Thierry, Carado, Julia, Martin Culet, Noëlie, Roger, Séverine, Cruz, Ignacio, Diego, Alejandro, Herrero, Jesús, Martín, Javier, Rodríguez, Javier, Moralejo, Ana, Sanchez Pablo, Clara, Sánchez, Nuria, Pinar, Eduardo, Duran, Juan M, Garcia de Lars, Juan, Gimeno, Juan R, Hurtado, Jose, Lacunza, Javier, Leithold, Gunnar, Lova, Alejandro, Valdesuso, Raul, Valles, Dolores, Vaquerizo, Beatriz, Millan, Raul, Rodriquez Costoya, Iris, Salvatella, Neus, Tizon Marcos, Helena, Cabero, Paula, Ivern, Consol, Sánchez Carpintero, Andrea, Soler, Cristina, Mainar, Vincente, Bordes, Pascual, Pineda, Javier, Ruiz Nodar, Juan Miguel, Valencia, José, Ajo, Maria, Ajo, Raquel, Unikas, Ramūnas, Braukylienė, Rima, Jaruševičius, Gediminas, Morkūnaitė, Kristina, Nemeikša, Sigitas, Pažereckaitė, Daiva, Bin Abdul Ghapar, Abdul Kahar, Bin Abdul Malek, Abdul Muizz, Bin Abdullah Ramaiah, Asri Ranga, Selvaraj, Kamaraj, Sivasubramaniam, Vanessa, Tay, Lip Kai, Binti Abdul Haq, Hafsah Begum, Binti Daud, Siti Rohaya, Binti Mohammad Zamri, Nur Aizah, Cequier, Ángel, Ferreiro, José Luís, Fuentes, Lara, Antoni Gómez, Joan, Gómez Lara, Josep, Gracida, Montserrat, León, Valentina, Romaguera, Rafael, Roura, Gerard, Teruel, Luis, Cañavate, Olga, Guerrero, Sonia, Rodríguez, Silvia, Bosa Ojeda, Francisco, Leiva, Miguel, Méndez Vargas, Corabel, Sánchez-Grande Flecha, Alejandro, Yanes Bowden, Geoffrey, de la Fuente Perdomo, Mária Belén, Moreno, Raul, Galeote Garcia, Guillermo, Jimenez Valero, Santiago, Pascual, Virgina, Sánchez Recalde, Angel, Albadalejo, Ainara, Fernández-Figares, Virgina, Mediavilla, Guiomar, Molins, Cristina, de la Torre Hernandez, Jose María, Garcia Camarero, Tamara, Hwang, Dae-Hyun Lee, Sainz Laso, Fermin, Veiga Fernandez, Gabriela, Windecker, Stephan, Billinger, Michael, Häner, Jonas, Pilgrim, Thomas, Praz, Fabien, Raeber, Lorenz, Siontis, Georgios, Spirito, Alessandro, Stortecky, Stefan, Valgimiglo, Marco, Bertschy, Magali, Fahrni, Therese, Morf, Laura, Sager, Ursina, Lumpur, Kuala, Malaysia, Malaysia, Bin Nuruddin, Amin Ariff, Arshad, Akmal Hakim, Bin Rosman, Azhari, Bin Wan Rahimi Shah, Faizal, Kolanthaivelu, Jayakhanthan, Penwala, Tanveer Iqbal, Teoh, Chee Kiang, Win, Nay Thu, Syamsi, Renobastian Nur, Selamat, Salizah, Kedhi, Elvin, Berta, Balazs, Gosselink, Antonius, Hermanides, Rik, Kaplan, Eliza, Ottervanger, Jan Paul, Roolvink, Vincent, van Leeuwen, Maarten, Yokota, S, Bouwhuis, Ilse, Rietdijk, Gijsbert Johan Adriaan, Schrijver, Claudia, van den Brink, Linda, van der Laan, Marielle, Henareh, Loghman, Desta, Liyew, Hassan, Shams, Jurga, Juliane, Mogensen, Brynjolfur, Venetsanos, Dimitros, Forstedt, Gunilla, Nylund, Lotta, Tarlinder, Teresia, Hur, Seung-Ho, Cho, Yun Kyeong, Han, Seongwook, Hwang, Jongmin, Kim, Hyung-Seop, Kim, In Cheol, Lee, Cheol Hyun, Nam, Chang-Wook, Park, Hyoung Seob, Yoon, Hyuck Joon, Kwon, So Young, Park, So Hyeon, Toth, Gabor, Buschmann, Eva, Luha, Olev, Schmidt, Albrecht, Zweiker, Robert, Flasch, Marlies, Gharibeh, Sarah, Praschk, Andreas, van 't Hof, Arnoud, Feld, Rob, Gho, Ben, Ilhan, Mustafa, Kietselaer, Bas, Rasoul, Saman, Ruiters, Alexander, Stein, Mèra, Theunissen, Ralph, Vainer, Jindrich, Veenstra, Leo, Baggen, Moniek, Berends-Sluijsmans, Debora, Douven, Odette, Hendrick, Rémon, Hessels-Linnemeijer, Brigitta, Kasperski, Ilse, Lardinois, Rob, Lousberg, Aimee, Włodarczak, Adrian, Jastrzębski, Artur, Pęcherzewski, Maciej, Szudrowicz, Marek, Chan, Koo Hui, Chan, Mark Yan Yee, Loh, Joshua Ping Yun, Loh, Poay Huan, Low, Adrian, Tan, Huay Cheem, Tay, Edgar Lik-Wui, Leong, Audrey Whye Yi, Sia, Winnie Chew Huang, Tan, Vion Sik Yin, Wong, Cher Yi, Opdahl, Anders, Fossum, Egil, Due-Tønnessen, Nicole, Halvorsen Egeland, Cecilie, Nesheim, Marianne, Montorfano, Matteo, Latib, Azeem, Altizio, Savino, Ancona, Marco, Bellini, Barbara, Gitto, Mauro, Godino, Cosmo, Rossi, Federica, Rusconi, Vega, Ērglis, Andrējs, Lesiņa, Krista, Narbute, Inga, Štrenge, Agnese, Grāve, Aļona, Tamburino, Corrado, Capranzano, Piera, D'Arrigo, Paolo, Dipasquale, Francesco, Francaviglia, Bruno, Garrahy, Paul, Camuglia, Anthony, Connors, Gerard, Cox, Stephen, Fetahovic, Taufik, Fogarty, Samuel, Gill, Daljeet, Harvey, Robert, Kang, Simon, Kaye, Gerald, Korczyk, Dariusz, Lim, Richard, McCann, Andrew Barry, Nguyen, Sean, Peverill, William, Robinson, James, Singbal, Yash, Thoreau, Jennifer, Wahi, Sudhir, Hall, Cindy, Lollbat, Naomi, Sieg, Charmaine, Anantharam, Brijesh, Strike, Philip, Dana, Ali, Haworth, Peter, Hobson, Alex, Kirubakaran, Senthil, Mahadevan, Kalaivani, Austin, Rosalynn, Howe, Serena, Scott, Kerrie, Suttling, Anne, Turner, Charlotte, Whitehead, Helena, Lee, Michael Kang-Yin, Chan, Alan Ka Chun, Chan, Kam Tim, Cheng, Yuet Wong, Chui, Shing Fung, Fu, Chiu Lai, Kwok, Kevin Chun Kit, Luk, Ngai Hong, Wong, Eric Chi Yuen, Chan, Cecilia, Leung, Jo Ka-Wai, Liew, Houng Bang, Ang, Kuan Hooi, Chan, Lee Lee, Chia, Chun Keat, Chin, Fah Shin, Chow, Kwok Kang, Chu, Chong Mow, Eng, Theng Sheng, Khaw, Yeong Mei, Lee, Kuo Ting, Murugesu, Kalaivani, Ng, Kai Choon, Saharudin, Sahrin, Salleh, Siti Nur Syuhada, Sekaran, Vithiyah, Sevalingam, Raj Kumar, Bin Syaripuddin, Alfieyanto, Tan, You Zhuan, Teoh, Eu Vin, Chong, Melanie Shu Theng, Jenarun, Grazele, Pungging, Normalah, Subramanian, Vimala Veni, Wong, Mabelle, Tam, Frankie, Chan, Eric Kwong Yue, Chan, Kelvin Ki Wan, Chan, Will Yap Hang, Fang, Jonathan, Lam, Simon Cheung Chi, Lam, Yui Ming, Shea, Catherine, Siu, David Chung Wah, Sze, Micheal Shu Yue, Tse, Hung-Fat, Un, Ka Chun, Wong, Anthony YiuTung, Yung, Arthur, Chan, Alice, Ho, Jerrical, Wong, Wendy Wen, Kalniņš, Artis, Ļebedeva, Sofija, Lisnovs, Artjoms, Hammett, Christopher, Hayman, Samual, Mew, Thomas, O'Sullivan, Patricia, Puchalski, Robert J, Shetty, Rajesh, Singh, Suhasini, Sowden, Nicholas, Stewart, Peter, Tomlinson, Stephen, Hindom, Linda, Lilwall, Lydia, Palethorpe, Leeanne, Ludman, Andrew, Sharp, Andrew, Renouf, Adrian, Adams, Lisa, Godbeer, Emma, Keenan, Samantha, Mackle, Daisy, Kalra, Sundeep, Manmathan, Gavin, Badhan, Gurpreet Rani, Bidle, Amanda, Burgwyn, Joshua, Crause, Jacolene, Davies, Nina, Deelchand, Vashist, Dimond, Kristy, Uren, Neal, Adamson, Philip, Behan, Miles, Cruden, Nick, Henriksen, Peter, Mills, Nick, Newby, David, Blair, Jane, Harrison, James, Paterson, Karen, Rif, Belinda, Bhindi, Ravinay, Dind, Ashleigh, Hansen, Peter, Harmer, Jason, Leung, James, McConnell, Eliza, Ward, Michael, Chui, Karina, Dent, Jill, Reid, Emma, Whitbourn, Robert, Adams, Heath, Burns, Andrew, Jones, Nicholas, Layland, Jamie, MacIsaac, Andrew, Palmer, Sonny, Wilson, Andrew, Read, Jeanette, Stewart, Natasha, Gwon, Hyeon Cheol, Choi, Seung-Hyuk, Hahn, Joo-Yong, Lee, Joo Myung, Park, Taek-Kyu, Song, Young Bin, Hee, Won Jin, Kim, Miran, Ong, Tiong Kiam, Binti Mohammad Amin, Nor Hanim, Cham, Yee Ling, Fong, Alan Yean Yip, Ho, Kian Hui, Khiew, Ning Zan, Said, Asri Bin, Shu, Francis Eng Pbeng, Voon, Chi Yen, Gundek, Ritem Anak, Binti Abdullah, Syamsukinah, Dize, Lindsy Anak Sylvester, Osman, Nur Fitri Yana, Sekon, Manyup Anak, Sulehan, Juriah Binti, Tay, Chung Moi, Voon, Siew Moi, Chae, In-Ho, Cho, Young-Seok, Kang, Si-Hyuck, Lee, Won Jae, Park, Jin-Joo, Suh, Jung-Won, Yoon, Chang-Hwan, Youn, Tae Jin, Go, Jin Kyung, Im, Na Hyun, Yun, Ji Yeon, Kim, Hyo Soo, Cho, Hyun-Jai, Han, Jung Kyu, Kang, Hyun-Jae, Kang, Jee Hoon, Koo, Bon Kwon, Park, Kyung-Woo, Yang, Hanmo, Jeong, Jae-Hoon, Lee, Jin Hwa, Chang, Kiyuk, Hwang, Byung Hee, Baek, Chun Young, Lee, Jae Hyun, Jang, Yangsoo, Ahn, Chul Min, Choi, Dong-Hoon, Hong, Myeong-Ki, Hong, Sung Jin, Kim, Byeong-Keuk, Kim, Joong Sun, Ko, Young-Guk, Cho, Yusun, Kim, So Young, Kim, Woo Sin, Tresukosol, Damras, Towashiraporn, Korakoth, Wongpraparut, Nattawut, Chaiphet, Olaree, Reanthong, Treenet, Witt, Nils, Alström, Patrik, Fedchenko, Nikolai, Jensen, Ulf, Santos Pardo, Irene, Ahlinder, Carolin, Blomberg, Elin, Korsell, Annette, Malkki, Katri, Österblom, Ulrika, Sundelin, Runa, Jan Suttorp, Maarten, Agostoni, Pierfrancesco, Arslan, Fatih, Arnoud, Mike, Bosschaert, Ramon, Eefting, Frank, Rensing, Bernard, Ten Berg, Jurriën, van den Akker, Bertinel, van Kuijk, Jan-Peter, Albersen, Inke, Gornelda Bras, Rebecca, Feirabend, Conny, Helwig-Vernooij, Johanna Catharina, Kranen, Gerda, Nakamura, Rosana, Oostveen, Manfred, Larsen, Alf Inge, Bogale, Nigussie, Bonarjee, Vernon, Ogne, Christer, Moen, Solfrid, Nilsen, Jorunn, Skadberg, Mette, Sletteboe, Inger Marie, Hudec, Martin, Gombaský, Marcel, Krajči, Peter, Kupec, Andrej, Poliačiková, Petra, Trenčan, Milan, Lesiak, Maciej, Dudek, Magdalena, Iwańczyk, Sylwia, Kałużna-Oleksy, Marta, Klotzka, Aneta, Przepióra, Agnieszka, Ong, Paul J L, Ho, Hee Hwa, Jafary, Fahim Hairder, Khoo, Deanna Zhi-Lin, Lee, Deborah Jin Hyun, Loh, Jason, Li, Cathy Haiyan, Ong, Elena See Peng, Tan, Geraldine Geok Cheng, Wong, Stephanie, Yu, Crystal Bo, Walton, Tony, Bloom, Jason, Chan, William, Duffy, Stephen, Freilich, Mark, Hengel, Christopher, Htun, Nay, Peter, Karlheinz, Prakash, Roshan, Shaw, James, Stehli, Julia, Stub, Dion, Davidson, Brianna, Hammond, Louise H, Holland, Samantha, Johnston, Rozanne, Muir, Douglas, Bawamia, Bilal, Chapman, Michael, Vahabi, Sharareh, Williams, Paul, Athorne, Deborah, Atkinson, Beverley, Donnelly, Anthony, Mack, Stephanie, Manders, Tracy, Richardson, Catherine, Zaman, Azfar, Ahmed, Javed, Bagnall, Alan, Das, Rajiv, Edwards, Richard, Egred, Mohaned, Purcell, Ian, Spyridopoulos, Ioakim, Adams, Jennifer, Arkley, Michael, Bailey, Angela, Ebejer, Michela, Harrison, Ursula, Hetherington, Suzanne, Hindmarch, Paul, Lamb, Sarah, Matsvimbo, Pamela, Procter, Katherine, Quinn, Louise, Ward, Jane, Wealleans, Vera, Raffel, Christopher, Aroney, Nicholas, Chan, Julian, Dautov, Rustem, Gaikwad, Niranjan, Gopal, Kathikeyan, Markham, Ryan, Mishra, Akshay, Poon, Karl, Putrino, Anthony, Beevors, Estelle, Chu, Winnie Lai Cheung, Janoschka, Bo, Mearns, Megan, Phillips, Sandra, Roxas, Maricel, Rymar, Irena, Spencer, Suzanne, Stibijl, Kathryn, Sardella, Gennaro, Infusino, Fabio, Salvi, Nicolo, van der Harst, Pim, de Koning, Marie-Sophie, Groot, Hilde, Lipsic, Erik, Pundziute, Gabija, Schurer, Remco, Tan, Yong, van den Heuvel, Aloysius, van der Werf, Rik, Fröbert, Ole, Calais, Fredrik, Dhaha, Usama, Josefsson, Johan, Kellerth, Thomas, Marton, Laszlo, Zagozdzon, Leszek, Eriksson, Annika, Eriksson, Sandra, Hansson, Liselotte, Johansson, Magnus, Karlstrom, Kristina, Larsson, Liselotte, Thorsson, Amanda, Törnkvist, Eva, Desmet, Walter, Adriaenssens, Tom, Bennett, Johan, Dubois, Christophe, Marynissen, Thomas, McCutcheon, Keir Robert Gregor, Sinnaeve, Peter, Broos, Karin, Claes, Marina, Reniers, Sarah, van Roey, Sabina, Diderholm, Erik, Grimfjärd, Per, Kåregren, Amra, Saman, Saidi, Skoglund Andersson, Camilla, Voldberg, Birgitta, Andersson, Carina, Lundqvist, Marika, Myllylä, Lotta, Troquay, Roel, Aydin, Selahattin, Duygun, Ayse, Eerens, Filip, Frenk, Lisa, Rahel, B M, Remkes, Wouter, Daniels, Richard, Doesborg, Loek, Hattu, Lilian, Peeters, Conny, Baranauskas, Arvydas, Abraitis, Vytautas, Davidavičius, Giedrius, Radauskaitė, Greta, Solovjova, Svetlana, Baltokaitė, Lina, Gaidamavičiūtė, Violeta, Urbonaitė, Eglė, Pasupati, Sanjeevan, Fisher, Raewyn, Hamilton, Fraser, Heald, Spencer, Khurana, Akshat, Vun Liew, Tze, Menon, Madhav, Michael, Amit, Ali, Faaez Mohammed, Nair, Rajesh, Nizar, Ahmad, Nunn, Christopher, Pera, Vijaya, Sebastian, Cherian, Thaneeru, Pavan, Wolbinski, Mariusz, Kirk, Melissa, Low, Liz, Pillay, Roselyn, Harding, Scott, Aitken, Andrew, Fairley, Sarah, Ranchord, Anil, Wilkins, Benjamin, Davies, Bronwyn, Middleditch, Diane, Wylie, Donna, Yoon, Junghan, Ahn, Min Soo, Ahn, Sung Gyun, Kim, Jang Young, Lee, Jun-Won, Lee, Seung Hwan, Park, Sang Wook, Son, Jung-Woo, Yoo, Byung-Su, Ahn, Hae Jung, Han, Sunhui, Jang, Hye Suk, Shin, Seon Mi, Woo, Jung Ja |
| المصدر: | New England Journal of Medicine, 382 (13), 1208-1218 (2020-03-26) |
| بيانات النشر: | Massachusetts Medical Society, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Immunosuppressive Agents, Platelet Aggregation Inhibitors, Polymers, H4GXR80IZE (zotarolimus), U36PGF65JH (umirolimus), W36ZG6FT64 (Sirolimus), Coronary Artery Disease/therapy, Coronary Thrombosis/etiology/mortality, Drug Therapy, Combination, Drug-Eluting Stents/adverse effects, Heart Diseases/mortality, Hemorrhage/chemically induced, Humans, Immunosuppressive Agents/administration & dosage, Kaplan-Meier Estimate, Percutaneous Coronary Intervention, Platelet Aggregation Inhibitors/adverse effects/therapeutic use, Prosthesis Design, Single-Blind Method, Sirolimus/administration & dosage/analogs & derivatives, Human health sciences, Cardiovascular & respiratory systems, Sciences de la santé humaine, Systèmes cardiovasculaire & respiratoire |
| الوصف: | BACKGROUND: Polymer-free drug-coated stents provide superior clinical outcomes to bare-metal stents in patients at high bleeding risk who undergo percutaneous coronary intervention (PCI) and are treated with 1 month of dual antiplatelet therapy. Data on the use of polymer-based drug-eluting stents, as compared with polymer-free drug-coated stents, in such patients are limited. METHODS: In an international, randomized, single-blind trial, we compared polymer-based zotarolimus-eluting stents with polymer-free umirolimus-coated stents in patients at high bleeding risk. After PCI, patients were treated with 1 month of dual antiplatelet therapy, followed by single antiplatelet therapy. The primary outcome was a safety composite of death from cardiac causes, myocardial infarction, or stent thrombosis at 1 year. The principal secondary outcome was target-lesion failure, an effectiveness composite of death from cardiac causes, target-vessel myocardial infarction, or clinically indicated target-lesion revascularization. Both outcomes were powered for noninferiority. RESULTS: A total of 1996 patients at high bleeding risk were randomly assigned in a 1:1 ratio to receive zotarolimus-eluting stents (1003 patients) or polymer-free drug-coated stents (993 patients). At 1 year, the primary outcome was observed in 169 of 988 patients (17.1%) in the zotarolimus-eluting stent group and in 164 of 969 (16.9%) in the polymer-free drug-coated stent group (risk difference, 0.2 percentage points; upper boundary of the one-sided 97.5% confidence interval [CI], 3.5; noninferiority margin, 4.1; P = 0.01 for noninferiority). The principal secondary outcome was observed in 174 patients (17.6%) in the zotarolimus-eluting stent group and in 169 (17.4%) in the polymer-free drug-coated stent group (risk difference, 0.2 percentage points; upper boundary of the one-sided 97.5% CI, 3.5; noninferiority margin, 4.4; P = 0.007 for noninferiority). CONCLUSIONS: Among patients at high bleeding risk who received 1 month of dual antiplatelet therapy after PCI, use of polymer-based zotarolimus-eluting stents was noninferior to use of polymer-free drug-coated stents with regard to safety and effectiveness composite outcomes. (Funded by Medtronic; ONYX ONE ClinicalTrials.gov number, NCT03344653.). |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501Test article peer reviewed |
| اللغة: | English |
| العلاقة: | urn:issn:0028-4793; urn:issn:1533-4406 |
| DOI: | 10.1056/NEJMoa1910021 |
| الوصول الحر: | https://orbi.uliege.be/handle/2268/292594Test |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2Test info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsorb.292594 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1056/NEJMoa1910021 |
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