دورية أكاديمية
Free fatty acid profiling of marine sentinels by nanoLC-EI-MS for the assessment of environmental pollution effects
| العنوان: | Free fatty acid profiling of marine sentinels by nanoLC-EI-MS for the assessment of environmental pollution effects |
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| المؤلفون: | Albergamo, A., Rigano, F., Purcaro, Giorgia, Mauceri, A., Fasulo, S., Mondello, L. |
| المصدر: | Science of the Total Environment, 571, 955-962 (2016) |
| بيانات النشر: | Elsevier B.V., 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Bioindicator, Biomonitoring, Environmental pollution, Free fatty acids (FFAs), M. galloprovincialis, NanoLC-EI-MS, Biomarkers, Ionization of liquids, Liquid chromatography, Marine pollution, Mass spectrometry, Molluscs, Nanotechnology, Phase separation, Pollution, Environmental pollutions, Free fatty acid, Nano-LC, Fatty acids, Article, Italy, Mytilus galloprovincialis, Mytilus, Animals, Chromatography, Liquid, Environmental Monitoring, Fatty Acids, Nonesterified, Water Pollutants, Chemical, Physical, chemical, mathematical & earth Sciences, Chemistry, Life sciences, Animal production & animal husbandry, Physique, chimie, mathématiques & sciences de la terre, Chimie, Sciences du vivant, Productions animales & zootechnie |
| الوصف: | The present work aims to elucidate the free fatty acid (FFA) profile of the mussel Mytilus galloprovincialis caged in an anthropogenically impacted area and in a reference site through an innovative and validated analytical approach for the assessment of biological alterations induced by marine pollution. The FFA pattern is involved in the regulation of different cellular pathways and differs with respect to metabolic stimuli. To this purpose, the lipid fraction of mussels coming from both sampling areas was extracted and the FFA fractions were isolated and purified by a solid phase extraction; then, nano-scale liquid chromatography coupled to electron ionization mass spectrometry (nanoLC-EI-MS) was employed for the characterization of the two samples. A total of 19 and 17 FFAs were reliably identified in the mussels coming from the reference and polluted site, respectively. Significant qualitative and quantitative differences found in saturated, monounsaturated and polyunsaturated species may be exploited as typical pollution biomarkers (e.g. alteration of the fatty acid biosynthetic system and lipotoxicity) and explain adverse and compromising effects (e.g. oxidative stress and inflammatory processes) related to environmental pollution. © 2016 Elsevier B.V. National Interest Research Project(PRIN 2010–2011, Prot. 2010ARBLT7_001/008) |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501Test article |
| اللغة: | English |
| العلاقة: | urn:issn:0048-9697; urn:issn:1879-1026 |
| DOI: | 10.1016/j.scitotenv.2016.07.082 |
| الوصول الحر: | https://orbi.uliege.be/handle/2268/231713Test |
| حقوق: | restricted access http://purl.org/coar/access_right/c_16ecTest info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsorb.231713 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1016/j.scitotenv.2016.07.082 |
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