دورية أكاديمية
Targeted temperature management after intraoperative cardiac arrest: a multicenter retrospective study.
| العنوان: | Targeted temperature management after intraoperative cardiac arrest: a multicenter retrospective study. |
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| المؤلفون: | Constant, Anne-Laure, Mongardon, Nicolas, Morelot, Quentin, Pichon, Nicolas, Grimaldi, David, Bordenave, Lauriane, Soummer, Alexis, Sauneuf, Bertrand, Merceron, Sybille, Ricome, Sylvie, Misset, Benoît, Bruel, Cedric, Schnell, David, Boisrame-Helms, Julie, Dubuisson, Etienne, Brunet, Jennifer, Lasocki, Sigismond, Cronier, Pierrick, Bouhemad, Belaid, Carreira, Serge, Begot, Emmanuelle, Vandenbunder, Benoit, Dhonneur, Gilles, Jullien, Philippe, Resche-Rigon, Matthieu, Bedos, Jean-Pierre, Montlahuc, Claire, Legriel, Stephane |
| المصدر: | Intensive Care Medicine, 43 (4), 485-495 (2017) |
| بيانات النشر: | Springer, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Adult, Aged, Body Temperature, Electric Countershock, Female, France/epidemiology, Heart Arrest/mortality/therapy, Humans, Hypothermia, Induced/adverse effects/methods, Intensive Care Units, Intraoperative Complications/mortality/therapy, Male, Middle Aged, Multivariate Analysis, Proportional Hazards Models, Retrospective Studies, Time Factors, Treatment Outcome, Cardiopulmonary resuscitation, Coma/therapy, Hypothermia, Induced, Intraoperative complications/therapy, Human health sciences, Anesthesia & intensive care, Sciences de la santé humaine, Anesthésie & soins intensifs |
| الوصف: | PURPOSE: Few outcome data are available about temperature management after intraoperative cardiac arrest (IOCA). We describe targeted temperature management (TTM) (32-34 degrees C) modalities, adverse events, and association with 1-year functional outcome in patients with IOCA. METHODS: Patients admitted to 11 ICUs after IOCA in 2008-2013 were studied retrospectively. The main outcome measure was 1-year functional outcome. RESULTS: Of the 101 patients [35 women and 66 men; median age, 62 years (interquartile range, 42-72)], 68 (67.3%) were ASA PS I to III and 57 (56.4%) had emergent surgery. First recorded rhythms were asystole in 44 (43.6%) patients, pulseless electrical activity in 36 (35.6%), and ventricular fibrillation/tachycardia in 20 (19.8%). Median times from collapse to cardiopulmonary resuscitation and return of spontaneous circulation (ROSC) were 0 min (0-0) and 10 min (4-20), respectively. The 30 (29.7%) patients who received TTM had an increased risk of infection (P = 0.005) but not of arrhythmia, bleeding, or metabolic/electrolyte disorders. By multivariate analysis, one or more defibrillation before ROSC was positively associated with a favorable functional outcome at 1-year (OR 3.06, 95% CI 1.05-8.95, P = 0.04) and emergency surgery was negatively associated with 1-year favorable functional outcome (OR 0.36; 95% CI 0.14-0.95, P = 0.038). TTM use was not independently associated with 1-year favorable outcome (OR 0.82; 95% CI 0.27-2.46, P = 0.72). CONCLUSIONS: TTM was used in less than one-third of patients after IOCA. TTM was associated with infection but not with bleeding or coronary events in this setting. TTM did not independently predict 1-year favorable functional outcome after IOCA in this study. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501Test article |
| اللغة: | English |
| العلاقة: | urn:issn:0342-4642; urn:issn:1432-1238 |
| DOI: | 10.1007/s00134-017-4709-0 |
| الوصول الحر: | https://orbi.uliege.be/handle/2268/245133Test |
| حقوق: | restricted access http://purl.org/coar/access_right/c_16ecTest info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsorb.245133 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1007/s00134-017-4709-0 |
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