دورية أكاديمية
A VQ-motif-containing protein fine-tunes rice immunity and growth by a hierarchical regulatory mechanism.
| العنوان: | A VQ-motif-containing protein fine-tunes rice immunity and growth by a hierarchical regulatory mechanism. |
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| المؤلفون: | Hao, Zeyun, Tian, Jinfu, Fang, Hong, Fang, Liang, Xu, Xiao, He, Feng, Li, Shaoya, Xie, Wenya, Du, Qiang, You, Xiaoman, Wang, Debao, Chen, Qiuhong, Wang, Ruyi, Zuo, Shimin, Yuan, Meng, Wang, Guo-Liang, Xia, Lanqin, Ning, Yuese |
| المصدر: | Cell Reports, 40 (7), 111235 (2022-08-16) |
| بيانات النشر: | Elsevier B.V., 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | CP: Plants, Magnaporthe oryzae, VQ-motif-containing protein, WRKY transcription factor, Xanthomonas oryzae pv.oryzae, broad-spectrum disease resistance, plant immunity, rice (Oryza sativa), transcriptional regulation, ubiquitin E3 ligase, ubiquitination, Plant Proteins, Transcription Factors, Ubiquitin-Protein Ligases, Disease Resistance, Gene Expression Regulation, Plant, Plant Diseases, Plant Proteins/genetics, Plant Proteins/metabolism, Transcription Factors/metabolism, Ubiquitin-Protein Ligases/genetics, Ubiquitin-Protein Ligases/metabolism, Xanthomonas, Magnaporthe/metabolism, Oryza/genetics, Oryza/metabolism, Oryza/microbiology, Magnaporthe, Oryza, Biochemistry, Genetics and Molecular Biology (all), General Biochemistry, Genetics and Molecular Biology, Life sciences, Agriculture & agronomy, Sciences du vivant, Agriculture & agronomie |
| الوصف: | Rice blast and bacterial blight, caused by the fungus Magnaporthe oryzae and the bacterium Xanthomonas oryzae pv. oryzae (Xoo), respectively, are devastating diseases affecting rice. Here, we report that a rice valine-glutamine (VQ) motif-containing protein, OsVQ25, balances broad-spectrum disease resistance and plant growth by interacting with a U-Box E3 ligase, OsPUB73, and a transcription factor, OsWRKY53. We show that OsPUB73 positively regulates rice resistance against M. oryzae and Xoo by interacting with and promoting OsVQ25 degradation via the 26S proteasome pathway. Knockout mutants of OsVQ25 exhibit enhanced resistance to both pathogens without a growth penalty. Furthermore, OsVQ25 interacts with and suppresses the transcriptional activity of OsWRKY53, a positive regulator of plant immunity. OsWRKY53 downstream defense-related genes and brassinosteroid signaling genes are upregulated in osvq25 mutants. Our findings reveal a ubiquitin E3 ligase-VQ protein-transcription factor module that fine-tunes plant immunity and growth at the transcriptional and posttranslational levels. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501Test article peer reviewed |
| اللغة: | English |
| العلاقة: | https://api.elsevier.com/content/article/PII:S221112472201052X?httpAccept=text/xmlTest; https://doi.org/10.1016/j.celrep.2022.111235Test; urn:issn:2211-1247 |
| DOI: | 10.1016/j.celrep.2022.111235 |
| الوصول الحر: | https://orbi.uliege.be/handle/2268/313572Test |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2Test info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsorb.313572 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.1016/j.celrep.2022.111235 |
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