مورد إلكتروني
Successful treatment of unresectable advanced rectal cancer with liver metastases by hemostasis re-irradiation of the rectal cancer and palliative low-dose whole-liver radiation therapy: a case report.
| العنوان: | Successful treatment of unresectable advanced rectal cancer with liver metastases by hemostasis re-irradiation of the rectal cancer and palliative low-dose whole-liver radiation therapy: a case report. |
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| عناروين إضافية: | Successful treatment of unresectable advanced rectal cancer with liver metastases by hemostasis re-irradiation of the rectal cancer and palliative low-dose whole-liver radiation therapy: a case report. Embago 12month (First Online: 18 July 2019) |
| بيانات النشر: | Springer 2020-01-14 2019-07-18 |
| تفاصيل مُضافة: | Yasuda, Takeshi Tanaka, Osamu Hayashi, Sadanari Nakahata, Yuki Yasuda, Yuriko Omatsu, Tatsushi Obora, Akihiro Kojima, Takao Matsuo, Masayuki Yagi, Nobuaki Department of Gastroenterology, Asahi University Hospital Department of Radiation Oncology, Asahi University Hospital Department of Gastroenterology, Asahi University Hospital Department of Gastroenterology, Asahi University Hospital Department of Gastroenterology, Asahi University Hospital Department of Gastroenterology, Asahi University Hospital Department of Gastroenterology, Asahi University Hospital Department of Gastroenterology, Asahi University Hospital Department of Radiology, Gifu University Hospital Department of Gastroenterology, Asahi University Hospital |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | A 72-year-old man was admitted to the hospital with fatigue. Colonoscopy revealed a 50 × 50mm rectal tumor with bleeding. Based on close inspection, he was diagnosed with unresectable advanced rectal cancer with multiple liver metastases. Chemotherapy was administered as 10 cycles of bevacizumab + mFOLFOX6 and 7 cycles of bevacizumab + FOLFIRI. Nine months later, he presented with hematochezia and progression of anemia. It was difficult to stop the bleeding via endoscopy. He underwent radiation therapy (39Gy in 13 fractions), and hemostasis was confirmed. Then, further chemotherapy was performed with 3 cycles of bevacizumab + FOLFIRI and 2 cycles of TAS102. However 14months after the initial visit, he presented with right hypochondralgia and abdominal fullness due to the progression of multiple liver metastases. Palliative low-dose whole-liver radiation therapy (WLRT) (30Gy in 10 fractions) was performed. He developed Grade 2 nausea, but his right hypochondralgia reduced, liver dysfunction improved, and he successfully completed radiotherapy. At approximately the same time his anemia progressed, and colonoscopy revealed recurrent bleeding from the tumor. Re-irradiation (15Gy in 5 fractions) of the rectal tumor was carried out and a blood transfusion was performed for the bleeding. He was discharged after confirmation the anemia had not progressed. Few reports have been published on the use of both palliative re-irradiation to stop bleeding from rectal cancer and palliative low-dose WLRT. Based on our experience with this case, we believe that palliative radiotherapy can be useful in treating patients with a poor prognosis. |
| مصطلحات الفهرس: | Hemostasis re-irradiation, Low-dose whole-liver irradiation, Palliative radiotherapy, Journal Article, AM |
| URL: | 31321737 |
| الإتاحة: | Open access content. Open access content CC BY-NC-ND |
| ملاحظة: | English |
| أرقام أخرى: | JPNII oai:irdb.nii.ac.jp:01469:0004546348 1865-7265 Clinical journal of gastroenterology 1378508998 |
| المصدر المساهم: | NATIONAL INST OF INFO From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1378508998 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |