مستخلص: Ruminococcus gnavus is a Gram-positive anaerobe and normal gut commensal in the human host. There have been a small number of reported cases of infections attributed to R. gnavus, and no cases of urogenital infections have previously been published. We describe here a case of bilateral tubo-ovarian abscesses (TOAs) which cultured a pure growth of R. gnavus in a young female with concurrent deep infiltrating endometriosis and evidence of pelvic inflammatory disease. This case provides an insight into the behaviour of R. gnavus as a coloniser of the human host and provides further incentive to investigate its potentially pathogenic role in inflammatory conditions such as pelvic inflammatory disease.Copyright © 2020 Elsevier Ltd

مصطلحات الفهرس: female, fever, Haemophilus influenzae, histopathology, human, human tissue, hysteroscopy, laparoscopic surgery, laparoscopy, lower abdominal pain, malaise, matrix assisted laser desorption ionization time of flight mass spectrometry, pelvic inflammatory disease/di [Diagnosis], priority journal, Ruminococcus, tuboovarian abscess/di [Diagnosis], tuboovarian abscess/dt [Drug Therapy], tuboovarian abscess/su [Surgery], vagina smear, x-ray computed tomography, amoxicillin plus clavulanic acid/dt [Drug Therapy], amoxicillin plus clavulanic acid/po [Oral Drug Administration], azithromycin/dt [Drug Therapy], azithromycin/iv [Intravenous Drug Administration], ceftriaxone/iv [Intravenous Drug Administration], levonorgestrel, metronidazole/dt [Drug Therapy], metronidazole/iv [Intravenous Drug Administration], oral contraceptive agent, mass spectrometer, Ruminococcus gnavus, ovary cyst/di [Diagnosis], C reactive protein/ec [Endogenous Compound], ceftriaxone/dt [Drug Therapy], abscess drainage, adult, anorexia, article, bacterium culture, bacterium identification, Candida albicans, case report, clinical article, dilatation and curettage, echography, endometriosis/di [Diagnosis], endometriosis/su [Surgery], Article

URL: https://repository.monashhealth.org/monashhealthjspui/handle/1/26948Test
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مستخلص: Ruminococcus gnavus is a Gram-positive anaerobe and normal gut commensal in the human host. There have been a small number of reported cases of infections attributed to R. gnavus, and no cases of urogenital infections have previously been published. We describe here a case of bilateral tubo-ovarian abscesses (TOAs) which cultured a pure growth of R. gnavus in a young female with concurrent deep infiltrating endometriosis and evidence of pelvic inflammatory disease. This case provides an insight into the behaviour of R. gnavus as a coloniser of the human host and provides further incentive to investigate its potentially pathogenic role in inflammatory conditions such as pelvic inflammatory disease.Copyright © 2020 Elsevier Ltd

مصطلحات الفهرس: female, fever, Haemophilus influenzae, histopathology, human, human tissue, hysteroscopy, laparoscopic surgery, laparoscopy, lower abdominal pain, malaise, matrix assisted laser desorption ionization time of flight mass spectrometry, pelvic inflammatory disease/di [Diagnosis], priority journal, Ruminococcus, tuboovarian abscess/di [Diagnosis], tuboovarian abscess/dt [Drug Therapy], tuboovarian abscess/su [Surgery], vagina smear, x-ray computed tomography, amoxicillin plus clavulanic acid/dt [Drug Therapy], amoxicillin plus clavulanic acid/po [Oral Drug Administration], azithromycin/dt [Drug Therapy], azithromycin/iv [Intravenous Drug Administration], ceftriaxone/iv [Intravenous Drug Administration], levonorgestrel, metronidazole/dt [Drug Therapy], metronidazole/iv [Intravenous Drug Administration], oral contraceptive agent, mass spectrometer, Ruminococcus gnavus, ovary cyst/di [Diagnosis], C reactive protein/ec [Endogenous Compound], ceftriaxone/dt [Drug Therapy], abscess drainage, adult, anorexia, article, bacterium culture, bacterium identification, Candida albicans, case report, clinical article, dilatation and curettage, echography, endometriosis/di [Diagnosis], endometriosis/su [Surgery], Article

URL: https://repository.monashhealth.org/monashhealthjspui/handle/1/26948Test
Anaerobe
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عناروين إضافية: Potential of Selected Rumen Bacteria for Cellulose and Hemicellulose Degradation

المصدر: Food Technology and Biotechnology; ISSN 1330-9862 (Print); ISSN 1334-2606 (Online); Volume 52; Issue 2

مستخلص: U probavnom se sustavu biljojeda nalaze vrlo učinkoviti mikroorganizmi što razgrađuju celulolozu i hemicelulozu iz sažvakanog biljnog materijala, te ih opskrbljuju hranjivim tvarima. Osim protozoa i gljivica, razgradnji otporne (hemi)celulozne biomase u buragu znatno pridonose i bakterije. U fokusu je ovog preglednog rada opis enzimskog sustava triju predstavnika bakterija iz buraga što proizvode celulazu, i to: Ruminococcus flavefaciens, Prevotella bryantii i Pseudobutyrivibrio xylanivorans. R. flavefaciens je poznat po proizvodnji jedne od najkompleksnijih enzimskih struktura, pa bi se mogao upotrijebiti za dizajn enzimskog kompleksa za razgradnju stanične stijenke biljaka. S druge strane, bakterije Prevotella bryantii i Pseudobutyrivibrio xylanivorans proizvode jednostavne, slobodne i vrlo aktivne ksilanaze. Bakterija P. xylanivorans ima i probiotička svojstva, pa se može upotrijebiti za proizvodnju bioplina i kao dodatak krmivu. Ispitivanje je genoma i proteoma bakterija što razgrađuju celulozu i hemicelulozu usmjereno na identifikaciju novih enzima, koji se nakon kloniranja i ekspresije u odgovarajućim domaćinima mogu upotrijebiti za izradu vrlo aktivnih rekombinantnih hidrolitičkih mikroorganizama, te primijeniti u različitim biotehnološkim procesima.
Herbivorous animals harbour potent cellulolytic and hemicellulolytic microorganisms that supply the host with nutrients acquired from degradation of ingested plant material. In addition to protozoa and fungi, rumen bacteria contribute a considerable part in the breakdown of recalcitrant (hemi)cellulosic biomass. The present review is focused on the enzymatic systems of three representative fibrolytic rumen bacteria, namely Ruminococcus flavefaciens, Prevotella bryantii and Pseudobutyrivibrio xylanivorans. R. flavefaciens is known for one of the most elaborated cellulosome architectures and might represent a promising candidate for the construction of designer cellulosomes. On the other hand, Prevotella bryantii and Pseudobutyrivibrio xylanivorans produce multiple free, but highly efficient xylanases. In addition, P. xylanivorans was also shown to have some probiotic traits, which makes it a promising candidate not only for biogas production, but also as an animal feed supplement. Genomic and proteomic analyses of cellulolytic and hemicellulolytic bacterial species aim to identify novel enzymes, which can then be cloned and expressed in adequate hosts to construct highly active recombinant hydrolytic microorganisms applicable for different biotechnological tasks.

مصطلحات الفهرس: Ruminococcus flavefaciens; Prevotella bryantii; Pseudobutyrivibrio xylanivorans; multienzimski kompleksi; ksilanaza; probiotici, Ruminococcus flavefaciens; Prevotella bryantii; Pseudobutyrivibrio xylanivorans; cellulosome; xylanase; probiotics, text, info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion

URL: https://hrcak.srce.hr/122346Test
https://hrcak.srce.hr/file/180846Test
https://hrcak.srce.hr/file/180845Test

مستخلص: Additional file 7: Table S5. Mean (standard deviation) of Bayes factors and cage variance ratio estimates for OTU that are influenced by cage effects and adjusted with the normal LMM. Table S6. Mean (standard deviation) of Bayes factor and cage variance ratio estimates for OTU that are influenced by cage effect and adjusted with the ZIP model. Tables S7. Bayes factors, marginal posterior means (standard deviations) of cage variance ratio for genera and alpha-diversity indices that are influenced by cage effects.

مصطلحات الفهرس: Marginal posterior distributions, g ., humans, Deviance information criterion, 16s rdna sequences, Model comparison regarding, Four microbial alpha, Complex microbial ecosystem, Rabbit cecum hosts, Linear model except, Host genetics shapes, 425 rabbits resulted, Included additive genetic, Bayes factor approach, 984 microbial traits, Specific microbial taxa, Host genetics, Bayes factor, Additive genetic, Model parameters, Microbial traits, Microbial diversity, Specific level, Rabbit microbiota, Mixed linear, Genetic control, Bayes factors, Systematic factors, Statistical distribution, Significant proportions, Significant proportion, Shannon indices, Several species, Several members, Results analysis, Relative abundances, Nursing environment, Inflated poisson, Global scale, Genus ruminococcus, Family s24, Environmental factors, Economic interest, Diversity indices, Cecal microbiota, Cattle, Body weight, dataset

URL: http://hdl.handle.net/10261/330065Test
https://doi.org/10.6084/m9.figshare.20167044.v1Test
Velasco‐Galilea, María; Piles, Miriam; Ramayo-Caldas, Yuliaxis; Varona, Luis; Sánchez, Juan Pablo. Use of Bayes factors to evaluate the effects of host genetics, litter and cage on the rabbit cecal microbiota. https://doi.org/10.1186/s12711-022-00738-2Test. http://hdl.handle.net/10261/287012Test
https://doi.org/10.6084/m9.figshare.20167044.v1Test
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مستخلص: Additional file 9: Table S9. Bayes factors, marginal posterior means and standard deviations of litter variance ratio for OTU influenced by litter effects together with the associated probability of these estimates being higher than 0.10. The frequency among the rabbit samples and the taxonomic assignment are also provided for each OTU.

مصطلحات الفهرس: Marginal posterior distributions, g ., humans, Deviance information criterion, 16s rdna sequences, Model comparison regarding, Four microbial alpha, Complex microbial ecosystem, Rabbit cecum hosts, Linear model except, Host genetics shapes, 425 rabbits resulted, Included additive genetic, Bayes factor approach, 984 microbial traits, Specific microbial taxa, Host genetics, Bayes factor, Additive genetic, Model parameters, Microbial traits, Microbial diversity, Specific level, Rabbit microbiota, Mixed linear, Genetic control, Bayes factors, Systematic factors, Statistical distribution, Significant proportions, Significant proportion, Shannon indices, Several species, Several members, Results analysis, Relative abundances, Nursing environment, Inflated poisson, Global scale, Genus ruminococcus, Family s24, Environmental factors, Economic interest, Diversity indices, Cecal microbiota, Cattle, Body weight, dataset

URL: http://hdl.handle.net/10261/330074Test
https://doi.org/10.6084/m9.figshare.20167050.v1Test
Velasco‐Galilea, María; Piles, Miriam; Ramayo-Caldas, Yuliaxis; Varona, Luis; Sánchez, Juan Pablo. Use of Bayes factors to evaluate the effects of host genetics, litter and cage on the rabbit cecal microbiota. https://doi.org/10.1186/s12711-022-00738-2Test. http://hdl.handle.net/10261/287012Test
https://doi.org/10.6084/m9.figshare.20167050.v1Test
Sí

مستخلص: Additional file 8: Table S8. Bayes factors, marginal posterior means and standard deviations of heritability estimates for OTU under genetic control together with the associated probability of these estimates being higher than 0.10. The frequency among the rabbit samples and the taxonomic assignment are also provided for each OTU.

مصطلحات الفهرس: Marginal posterior distributions, g ., humans, Deviance information criterion, 16s rdna sequences, Model comparison regarding, Four microbial alpha, Complex microbial ecosystem, Rabbit cecum hosts, Linear model except, Host genetics shapes, 425 rabbits resulted, Included additive genetic, Bayes factor approach, 984 microbial traits, Specific microbial taxa, Host genetics, Bayes factor, Additive genetic, Model parameters, Microbial traits, Microbial diversity, Specific level, Rabbit microbiota, Mixed linear, Genetic control, Bayes factors, Systematic factors, Statistical distribution, Significant proportions, Significant proportion, Shannon indices, Several species, Several members, Results analysis, Relative abundances, Nursing environment, Inflated poisson, Global scale, Genus ruminococcus, Family s24, Environmental factors, Economic interest, Diversity indices, Cecal microbiota, Cattle, Body weight, dataset

URL: http://hdl.handle.net/10261/330067Test
https://doi.org/10.6084/m9.figshare.20167047.v1Test
Velasco‐Galilea, María; Piles, Miriam; Ramayo-Caldas, Yuliaxis; Varona, Luis; Sánchez, Juan Pablo. Use of Bayes factors to evaluate the effects of host genetics, litter and cage on the rabbit cecal microbiota. https://doi.org/10.1186/s12711-022-00738-2Test. http://hdl.handle.net/10261/287012Test
https://doi.org/10.6084/m9.figshare.20167047.v1Test
Sí

مستخلص: Additional file 10: Table S10. Bayes factors, marginal posterior means and standard deviations of cage variance ratio for OTU influenced by cage effects together with the associated probability of these estimates being higher than 0.10. The frequency among the rabbit samples and the taxonomic assignment are also provided for each OTU.

مصطلحات الفهرس: Marginal posterior distributions, g ., humans, Deviance information criterion, 16s rdna sequences, Model comparison regarding, Four microbial alpha, Complex microbial ecosystem, Rabbit cecum hosts, Linear model except, Host genetics shapes, 425 rabbits resulted, Included additive genetic, Bayes factor approach, 984 microbial traits, Specific microbial taxa, Host genetics, Bayes factor, Additive genetic, Model parameters, Microbial traits, Microbial diversity, Specific level, Rabbit microbiota, Mixed linear, Genetic control, Bayes factors, Systematic factors, Statistical distribution, Significant proportions, Significant proportion, Shannon indices, Several species, Several members, Results analysis, Relative abundances, Nursing environment, Inflated poisson, Global scale, Genus ruminococcus, Family s24, Environmental factors, Economic interest, Diversity indices, Cecal microbiota, Cattle, Body weight, dataset

URL: http://hdl.handle.net/10261/329995Test
https://doi.org/10.6084/m9.figshare.20167020.v1Test
Velasco‐Galilea, María; Piles, Miriam; Ramayo-Caldas, Yuliaxis; Varona, Luis; Sánchez, Juan Pablo. Use of Bayes factors to evaluate the effects of host genetics, litter and cage on the rabbit cecal microbiota. https://doi.org/10.1186/s12711-022-00738-2Test. http://hdl.handle.net/10261/287012Test
https://doi.org/10.6084/m9.figshare.20167020.v1Test
Sí

مستخلص: Additional file 4: Figure S1. Geweke z-statistics for genetic, litter and cage variance ratios computed for the microbial traits that were better adjusted with the normal linear mixed model.

مصطلحات الفهرس: Marginal posterior distributions, g ., humans, Deviance information criterion, 16s rdna sequences, Model comparison regarding, Four microbial alpha, Complex microbial ecosystem, Rabbit cecum hosts, Linear model except, Host genetics shapes, 425 rabbits resulted, Included additive genetic, Bayes factor approach, 984 microbial traits, Specific microbial taxa, Host genetics, Bayes factor, Additive genetic, Model parameters, Microbial traits, Microbial diversity, Specific level, Rabbit microbiota, Mixed linear, Genetic control, Bayes factors, Systematic factors, Statistical distribution, Significant proportions, Significant proportion, Shannon indices, Several species, Several members, Results analysis, Relative abundances, Nursing environment, Inflated poisson, Global scale, Genus ruminococcus, Family s24, Environmental factors, Economic interest, Diversity indices, Cecal microbiota, Cattle, Body weight, dataset

URL: http://hdl.handle.net/10261/330019Test
https://doi.org/10.6084/m9.figshare.20167035.v1Test
Velasco‐Galilea, María; Piles, Miriam; Ramayo-Caldas, Yuliaxis; Varona, Luis; Sánchez, Juan Pablo. Use of Bayes factors to evaluate the effects of host genetics, litter and cage on the rabbit cecal microbiota. https://doi.org/10.1186/s12711-022-00738-2Test. http://hdl.handle.net/10261/287012Test
https://doi.org/10.6084/m9.figshare.20167035.v1Test
Sí

مستخلص: Additional file 5: Figure S2. Geweke z-statistics for genetic, litter and cage variance ratios computed for the microbial traits that were better adjusted with the zero-inflated Poisson model.

مصطلحات الفهرس: Marginal posterior distributions, g ., humans, Deviance information criterion, 16s rdna sequences, Model comparison regarding, Four microbial alpha, Complex microbial ecosystem, Rabbit cecum hosts, Linear model except, Host genetics shapes, 425 rabbits resulted, Included additive genetic, Bayes factor approach, 984 microbial traits, Specific microbial taxa, Host genetics, Bayes factor, Additive genetic, Model parameters, Microbial traits, Microbial diversity, Specific level, Rabbit microbiota, Mixed linear, Genetic control, Bayes factors, Systematic factors, Statistical distribution, Significant proportions, Significant proportion, Shannon indices, Several species, Several members, Results analysis, Relative abundances, Nursing environment, Inflated poisson, Global scale, Genus ruminococcus, Family s24, Environmental factors, Economic interest, Diversity indices, Cecal microbiota, Cattle, Body weight, dataset

URL: http://hdl.handle.net/10261/330061Test
https://doi.org/10.6084/m9.figshare.20167038.v1Test
Velasco‐Galilea, María; Piles, Miriam; Ramayo-Caldas, Yuliaxis; Varona, Luis; Sánchez, Juan Pablo. Use of Bayes factors to evaluate the effects of host genetics, litter and cage on the rabbit cecal microbiota. https://doi.org/10.1186/s12711-022-00738-2Test. http://hdl.handle.net/10261/287012Test
https://doi.org/10.6084/m9.figshare.20167038.v1Test
Sí

مستخلص: Additional file 1: Table S1. Metadata associated with the 425 rabbit cecal samples analyzed in this study.

مصطلحات الفهرس: Marginal posterior distributions, g ., humans, Deviance information criterion, 16s rdna sequences, Model comparison regarding, Four microbial alpha, Complex microbial ecosystem, Rabbit cecum hosts, Linear model except, Host genetics shapes, 425 rabbits resulted, Included additive genetic, Bayes factor approach, 984 microbial traits, Specific microbial taxa, Host genetics, Bayes factor, Additive genetic, Model parameters, Microbial traits, Microbial diversity, Specific level, Rabbit microbiota, Mixed linear, Genetic control, Bayes factors, Systematic factors, Statistical distribution, Significant proportions, Significant proportion, Shannon indices, Several species, Several members, Results analysis, Relative abundances, Nursing environment, Inflated poisson, Global scale, Genus ruminococcus, Family s24, Environmental factors, Economic interest, Diversity indices, Cecal microbiota, Cattle, Body weight, dataset

URL: http://hdl.handle.net/10261/330003Test
https://doi.org/10.6084/m9.figshare.20167023.v1Test
Velasco‐Galilea, María; Piles, Miriam; Ramayo-Caldas, Yuliaxis; Varona, Luis; Sánchez, Juan Pablo. Use of Bayes factors to evaluate the effects of host genetics, litter and cage on the rabbit cecal microbiota. https://doi.org/10.1186/s12711-022-00738-2Test. http://hdl.handle.net/10261/287012Test
https://doi.org/10.6084/m9.figshare.20167023.v1Test
Sí