-
1مورد إلكتروني
المؤلفون: Okhuarobo, Agbonlahor
المصدر: Alcohol (Hanover, York County, Pa.); vol 47, iss 2, 336-347; 0145-6008
مصطلحات الفهرس: Animals, Mice, Inbred C57BL, Alcoholism, Ethanol, Proto-Oncogene Proteins c-fos, Stress, Psychological, Alcohol Drinking, Female, early-life stress, hyperkatifeia, pain, resilience, vulnerability, Neurosciences, Behavioral and Social Science, Basic Behavioral and Social Science, Substance Misuse, Alcohol Use and Health, Good Health and Well Being, Clinical Sciences, Psychology, Substance Abuse, article
-
2مورد إلكتروني
المؤلفون: Galer, Erika L
المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience; vol 43, iss 3, 419-432; 0270-6474
مصطلحات الفهرس: Spinal Cord, Neurons, Animals, Rats, Somatostatin, Proto-Oncogene Proteins c-fos, Electric Stimulation, Female, Male, Respiratory Rate, Cervical Cord, cervical spinal cord, epidural stimulation, somatostatin, Neurodegenerative, Lung, Neurosciences, Neurological, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery, article
-
3مورد إلكتروني
المصدر: Molecular and cellular biology, 29 (20
مصطلحات الفهرس: Sciences bio-médicales et agricoles, Breast Neoplasms -- genetics, Breast Neoplasms -- pathology, Cell Line, Tumor, Chromatin -- metabolism, Ergosterol -- analogs & derivatives, Ergosterol -- pharmacology, Gene Expression Regulation, Neoplastic -- drug effects, Histones -- metabolism, Humans, Interleukin-6 -- genetics, Neoplasm Metastasis, Promoter Regions, Genetic -- physiology, Proto-Oncogene Proteins c-fos -- antagonists & inhibitors, Proto-Oncogene Proteins c-fos -- metabolism, Proto-Oncogene Proteins c-jun -- metabolism, RNA, Small Interfering -- metabolism, Transcription Factor AP-1 -- antagonists & inhibitors, Transcription Factor AP-1 -- metabolism, Transcription Factor RelA -- antagonists & inhibitors, Transcription Factor RelA -- metabolism, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article
-
4مورد إلكتروني
عناروين إضافية: Veränderung der formalinbedingten c-fos-ähnlichen Immunreaktivität im Rückenmark infolge Stress und Behandlung mit Morphin und Ketoamin
المصدر: GMS German Medical Science; VOL: 6; DOC05 /20080630/
مصطلحات الفهرس: RATS, ANIMALS, RATS, SPRAGUE-DAWLEY/metabolism, STRESS, PSYCHOLOGICAL, STRESS, PSYCHOLOGICAL/*metabolism, PROTO-ONCOGENE PROTEINS C-FOS, PROTO-ONCOGENE PROTEINS C-FOS/*biosynthesis, PROTO-ONCOGENE PROTEINS C-FOS/*drug effects, FORMALDEHYDE/pharmacology, MORPHINE/pharmacology, KETAMINE/pharmacology, ANALGESIA/psychology, PAIN, PAIN/*metabolism, COMPARATIVE STUDY, RATTUS, TIER, RATTEN, SPRAGUE-DAWLEY-/Stoffwechsel, STREß, PSYCHOLOGISCHER, STREß, PSYCHOLOGISCHER/*Stoffwechsel, PROTO-ONKOGEN-PROTEINE C-FOS, PROTO-ONKOGEN-PROTEINE C-FOS/*Biosynthese, PROTO-ONKOGEN-PROTEINE C-FOS/*Arzneimittelwirkungen, FORMALDEHYD/Pharmakologie, MORPHIN/Pharmakologie, KETAMIN/Pharmakologie, ANALGESIE/Psychologie, SCHMERZEN, SCHMERZEN/*Stoffwechsel, VERGLEICHENDE STUDIE, Fos, stress, pain, formalin, morphine, ketamine, c-fos, Stress, Schmerz, Formalin, Morphin, Ketoamin, ddc: 610, article
URL:
http://www.egms.de/en/journals/gms/2008-6/000050.shtmlTest
Abbadie C, Taylor BK, Peterson MA, Basbaum AI. Differential contribution of the two phases of the formalin test to the pattern of c-fos expression in the rat spinal cord: studies with remifentanil and lidocaine. Pain. 1997;69(1-2):101-10.
Abbadie C, Besson JM. C-fos expression in rat lumbar spinal cord following peripheral stimulation in adjuvant-induced arthritic and normal rats. Brain Res. 1993;607(1-2):195-204.
Aida S, Yamakura T, Baba H, Taga K, Fukuda S, Shimoji K. Preemptive analgesia by intravenous low-dose ketamine and epidural morphine in gastrectomy: a randomized double-blind study. Anesthesiology. 2000;92(6):1624-30.
Amit Z, Galina ZH. Stress-induced analgesia: adaptive pain suppression. Physiol Rev. 1986;66(4):1091-120.
Annetta MG, Iemma D, Garisto C, Tafani C, Proietti R. Ketamine: new indications for an old drug. Curr Drug Targets. 2005;6(7): 789-94.
Benrath J, Brechtel C, Stark J, Sandkühler J. Low dose of S+-ketamine prevents long-term potentiation in pain pathways under strong opioid analgesia in the rat spinal cord in vivo. Br J Anaesth. 2005;95(4):518-23.
Bontempi B, Sharp FR. Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area. J Neurosci. 1997;17(21):8596-612.
Bruijnzeel AW, Stam R, Compaan JC, Croiset G, Akkermans LM, Olivier B, Wiegant VM. Long-term sensitization of Fos-responsivity in the rat central nervous system after a single stressful experience. Brain Res. 1999;819(1-2):15-22.
Castro AR, Pinto M, Lima D, Tavares I. Imbalance between the expression of NK1 and GABAB receptors in nociceptive spinal neurons during secondary hyperalgesia: a c-Fos study in the monoarthritic rat. Neuroscience. 2005;132(4):905-16.
Catheline G, Le Guen S, Besson JM. Effects of opioid receptor antagonists on the effects of i.v. morphine on carrageenin evoked c-Fos expression in the superficial dorsal horn of the rat spinal cord. Brain Res. 1999;824(1):105-11.
Chaplan SR, Malmberg AB, Yaksh TL. Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. J Pharmacol Exp Ther. 1997;280:829-38.
Choe H, Choi YS, Kim YH, Ko SH, Choi HG, Han YJ, Song HS. Epidural morphine plus ketamine for upper abdominal surgery: improved analgesia from preincisional versus postincisional administration. Anesth Analg. 1997;84(3):560-3.
Costa A, Smeraldi A, Tassorelli C, Greco R, Nappi G. Effects of acute and chronic restraint stress on nitroglycerin-induced hyperalgesia in rats. Neurosci Lett. 2005;383(1-2):7-11.
Crane JW, French KR, Buller KM. Patterns of neuronal activation in the rat brain and spinal cord in response to increasing durations of restraint stress. Stress. 2005;8(3):199-211.
Curran T, Teich NM. Identification of a 39,000-dalton protein in cells transformed by the FBJ murine osteosarcoma virus. Virology. 1982;116(1):221-35.
De Bruin JT, Schäfer MK, Krohne HW, Dreyer A. Preoperative anxiety, coping, and intraoperative adjustment: Are there mediating effects of stress-induced analgesia? Psychol Health. 2001;16(3):253-71.
Deutsch SI, Mastropaolo J, Riggs RL, Rosse RB. The antiseizure efficacies of MK-801, phencyclidine, ketamine, and memantine are altered selectively by stress. Pharmacol Biochem Behav. 1997;58(3):709-12.
Dickenson AH, Chapman V, Green GM. The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cord. Gen Pharmacol. 1997;28(5):633-8.
Dubuisson D, Dennis SG. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain. 1977;4(2):161-74.
de Lange RP, Geerse GJ, Dahlhaus M,van Laar TJ, Wiegant VM, Stam R. Altered brain stem responsivity to duodenal pain after a single stressful experience. Neurosci Lett. 2005;381(1-2):144-8.
Ebersberger A, Anton F, Tolle TR, Zieglgänsberger W. Morphine, 5-HT2 and 5-HT3 receptor antagonists reduce c-fos expression in the trigeminal nuclear complex following noxious chemical stimulation of the rat nasal mucosa. Brain Res. 1995;676(2):336-42.
Frenkel C, Urban BW. Molecular actions of racemic ketamine on human CNS sodium channels. Br J Anaesth. 1992;69(3):292-7.
Fu ES, Miguel R, Scharf JE. Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery. Anesth Analg. 1997;84(5):1086-90.
Gilron I, Quirion R, Coderre TJ. Pre- versus postformalin effects of ketamine or large-dose alfentanil in the rat: discordance between pain behavior and spinal Fos-like immunoreactivity. Anesth Analg. 1999;89(1):128-35.
Gilron I, Coderre TJ. Novel targets of pain modulation in anaesthesia: preventing painful memories. Can J Anaesth. 1997;44(5 Pt 1):457-62.
Gogas KR, Cho HJ, Botchkina GI, Levine JD, Basbaum AI. Inhibition of noxious stimulus-evoked pain behaviors and neuronal fos-like immunoreactivity in the spinal cord of the rat by supraspinal morphine. Pain. 1996;65(1):9-15.
Grau JW. The central representation of an aversive event maintains the opioid and nonopioid forms of analgesia. Behav Neurosci. 1987;101(2):272-88.
Graven-Nielsen T, Aspegren Kendall S, Henriksson KG, Bengtsson M, Sörensen J, Johnson A, Gerdle B, Arendt-Nielsen L. Ketamine reduces muscle pain, temporal summation, and referred pain in fibromyalgia patients. Pain. 2000;85(3):483-91.
Hao JX, Sjölund BH, Wiesenfeld-Hallin Z. Electrophysiological evidence for an antinociceptive effect of ketamine in the rat spinal cord. Acta Anaesthesiol Scand. 1998;42(4):435-41.
Hao S, Takahata O, Mamiya K, Iwasaki H. Sevoflurane suppresses noxious stimulus-evoked expression of Fos-like immunoreactivity in the rat spinal cord via activation of endogenous opioid systems. Life Sci. 2002;71(5):571-80.
Harris JA. Using c-fos as a neural marker of pain. Brain Res Bull. 1998;45(1):1-8.
Harris JA, Westbrook RF, Duffield TQ, Bentivoglio M. Fos expression in the spinal cord is suppressed in rats displaying conditioned hypoalgesia. Behav Neurosci. 1995;109(2):320-8.
Herbert J. Fortnighly review. Stress, the brain, and mental illness. BMJ. 1997;315(7107):530-5.
Herdegen T, Leah JD. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res Brain Res Rev. 1998;28(3):370-490.
Hoffman GE, Lyo D. Anatomical markers of activity in neuroendocrine systems: Are we all 'fos-ed out'? J Neuroendocrinol. 2002;14(4):259-68.
Huang W, Simpson RK Jr. Ketamine suppresses c-fos expression in dorsal horn neurons after acute constrictive sciatic nerve injury in the rat. Neurosci Lett. 1999;269(3):165-8.
Hunt SP, Pini A, Evan G. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature. 1987;328(6131):632-4.
Jaksch W, Lang S, Reichhalter R, Raab G, Dann K, Fitzal S. Perioperative small-dose S(+)-ketamine has no incremental beneficial effects on postoperative pain when standard-practice opioid infusions are used. Anesth Analg. 2002;94(4):981-6.
Jennings E, Fitzgerald M. C-fos can be induced in the neonatal rat spinal cord by both noxious and innocuous peripheral stimulation. Pain. 1996;68(2-3):301-6.
Ji RR, Rupp F. Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos induction. J Neurosci. 1997;17(5):1776-85.
Kamei J, Hitosugi H, Misawa M, Nagase H, Kasuya Y. Delta-Opioid receptor-mediated forced swimming stress-induced antinociception in the formalin test. Psychopharmacology (Berl.). 1993;113(1):15-8.
Kawamata T, Omote K, Sonoda H, Kawamata M, Namiki A. Analgesic mechanisms of ketamine in the presence and absence of peripheral inflammation. Anesthesiology. 2000;93(2): 520-8.
Koizuka S, Obata H, Sasaki M, Saito S, Goto F. Systemic ketamine inhibits hypersensitivity after surgery via descending inhibitory pathways in rats. Can J Anaesth. 2005;52(5):498-505.
Kosek E, Lundberg L. Segmental and plurisegmental modulation of pressure pain thresholds during static muscle contractions in healthy individuals. Eur J Pain. 2003;7(3):251-8.
Kovelowski CJ, Raffa RB, Porreca F. Tramadol and its enantiomers differentially suppress c-fos-like immunoreactivity in rat brain and spinal cord following acute noxious stimulus. Eur J Pain. 1998;2(3):211-9.
Kucuk N, Kizilkaya M, Tokdemir M. Preoperative epidural ketamine does not have a postoperative opioid sparing effect. Anesth Analg. 1998;87(1):103-6.
Labuz D, Chocyk A, Wedzony K, Toth G, Przewlocka B. Endomorphin-2, deltorphin II and their analogs suppress formalin-induced nociception and c-Fos expression in the rat spinal cord. Life Sci. 2003;73(4):403-12.
Lee IO, Lee IH, Lee KC. Pre-versus post-formalin effects of intrathecal ketamine on spinal Fos-like immunoreactivity in rats. Indian J Med Res. 2004;120(6):527-33.
Lee IO, Lee IH. Systemic, but not Intrathecal, Ketamine Produces Preemptive Analgesia in the Rat Formalin Model. Acta Anaesthesiol Sin. 2001;39(3):123-7.
Liu RJ, Qiang M, Qiao JT. Nociceptive c-fos expression in supraspinal areas in avoidance of descending suppression at the spinal relay station. Neuroscience. 1998;85(4):1073-1087.
Matsumoto N, Kawarada K, Kamata K, Suzuki TA. Electrical stimulation of tooth pulp increases the expression of c-fos in the cat supraoptic nucleus but not in the paraventricular nucleus. Life Sci. 1993;53(15):1235-41.
Molander C, Xu Q, Grant G. The cytoarchitectonic organization of the spinal cord in the rat. I. The lower thoracic and lumbosacral cord. J Comp Neurol. 1984;230(1):133-41.
Nakao S, Miyamoto E, Masuzawa M, Kambara T, Shingu K. Ketamine-induced c-Fos expression in the mouse posterior cingulate and retrosplenial cortices is mediated not only via NMDA receptors but also via sigma receptors. Brain Res. 2002;926(1-2):191-6.
Rittner HL, Stein C. Involvement of cytokines, chemokines and adhesion molecules in opioid analgesia. Eur J Pain. 2005;9(2):109-12.
Sawamura S, Fujinaga M, Kingery WS, Belanger N, Davies MF, Maze M. Opioidergic and adrenergic modulation of formalin-evoked spinal c-fos mRNA expression and nocifensive behavior in the rat. Eur J Pharmacol. 1999;379(2-3):141-9.
Sawynok J, Reid A. Modulation of formalin-induced behaviors and edema by local and systemic administration of dextromethorphan, memantine and ketamine. Eur J Pharmacol. 2002;450(2):153-62.
Sevostianova N, Danysz W, Bespalov AY. Analgesic effects of morphine and loperamide in the rat formalin test: Interactions with NMDA receptor antagonists. Eur J Pharmacol. 2005;525(1-3):83-90.
Shibata M, Ohkubo T, Takahashi H, Inoki R. Modified formalin test: characteristic biphasic pain response. Pain. 1989;38: 347-52.
Shimoyama M, Shimoyama N, Gorman AL, Elliott KJ, Inturrisi CE. Oral ketamine is antinociceptive in the rat formalin test: role of the metabolite, norketamine. Pain. 1999;81(1-2):85-93.
Sun WZ, Shyu BC, Shieh JY. Nitrous oxide or halothane, or both, fail to suppress c-fos expression in rat spinal cord dorsal horn neurones after subcutaneous formalin. Br J Anaesth. 1996;76(1):99-105.
Tateyama S, Ikeda T, Kosai K, Nakamura T, Kasaba T, Takasaki M, Nishimori T. Endomorphins suppress nociception-induced c-Fos and Zif/268 expression in the rat spinal dorsal horn. Eur J Pharmacol. 2002;451(1):79-87.
Tjølsen A, Berge OG, Hunskaar S, Rosland JH, Hole K. The formalin test: an evaluation of the method. Pain. 1992;51:5-17.
Ueyama T, Saika M, Koreeda C, Senba E. Water immersion-restraint stress induces expression of immediate-early genes in gastrointestinal tract of rats. Am J Physiol. 1998;275(2 Pt 1):G287-95.
Vaccarino AL, Marek P, Liebeskind JC. Stress-induced analgesia prevents the development of the tonic, late phase of pain produced by subcutaneous formalin. Brain Res. 1992;572(1-2):250-2.
Vanderah TW, Wild KD, Takemori AE, Sultana M, Portoghese PS, Bowen WD, Mosberg HI, Porreca F. Mediation of swim-stress antinociception by the opioid delta 2 receptor in the mouse. J Pharmacol Exp Ther. 1992;262(1):190-7.
Vendruscolo LF, Pamplona FA, Takahashi RN. Strain and sex differences in the expression of nociceptive behavior and stress-induced analgesia in rats. Brain Res. 2004;1030(2):277-83.
Warncke T, Stubhaug A, Jørum E. Preinjury treatment with morphine or ketamine inhibits the development of experimentally induced secondary hyperalgesia in man. Pain. 2000;86(3):293-303.
Woda A, Blanc O, Voisin DL, Coste J, Molat JL, Luccarini P. Bidirectional modulation of windup by NMDA receptors in the rat spinal trigeminal nucleus. Eur J Neurosci. 2004;19(8):2009-16.
Yamamoto T, Yaksh TL. Comparison of the antinociceptive effects of pre- and post-treatment with intrathecal morphine and MK801, an NMDA antagonist, on the formalin test in the rat. Anesthesiology. 1992;77(4):757-63.
Zhang SP, Zhang JS, Yung KK, Zhang HQ. Non-opioid-dependent anti-inflammatory effects of low frequency electroacupuncture. Brain Res Bull. 2004;62(4):327-34.
Zou CJ, Liu JD, Zhou YC. Roles of central interleukin-1 on stress-induced-hypertension and footshock-induced-analgesia in rats. Neurosci Lett. 2001;311(1):41-4. -
5مورد إلكتروني
المصدر: World journal of gastroenterology, Vol. 28, no.48, p. 6935-6949 (2022)
مصطلحات الفهرس: Rats, Male, Mice, Animals, Urinary Bladder, Proto-Oncogene Proteins c-fos, CX3C Chemokine Receptor 1, Rats, Sprague-Dawley, Green Fluorescent Proteins, Mice, Inbred C57BL, Spinal Cord, Inflammation, Colorectal Neoplasms, Cross-organ sensitization, MAPK-p38, Microglia, NK1 receptor, Pain, Visceral hypersensitivity, info:eu-repo/semantics/article
-
6مورد إلكتروني
المصدر: Scientific Reports vol.12 (2022) date: 2022-11-29 nr.1 p.20571 [ISSN 2045-2322]
مصطلحات الفهرس: Animals, Mice, Transcranial Magnetic Stimulation, Parvalbumins, Brain, Antibodies, Light, Proto-Oncogene Proteins c-fos, Graft vs Host Disease, Artikel, Article
-
7مورد إلكتروني
المصدر: Biochemical and biophysical research communications, 337 (4
مصطلحات الفهرس: Sciences bio-médicales et agricoles, Cell Line, Culture Media, Serum-Free -- pharmacology, Gene Expression Regulation -- drug effects, Humans, Protein Binding, Proteomics, Proto-Oncogene Proteins c-fos -- genetics, Proto-Oncogene Proteins c-fos -- metabolism, Small Ubiquitin-Related Modifier Proteins -- metabolism, Substrate Specificity, Transcription Factors -- genetics, Transcription Factors -- metabolism, Transcription, Genetic -- drug effects, Transcription, Genetic -- genetics, 2D PAGE, H2O 2, MALDI-TOF, ROS, Stress, Substrate, SUMO, Sumoylation, Ubiquitylation, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article
-
8مورد إلكتروني
المصدر: Biochemical and biophysical research communications, 337 (4
مصطلحات الفهرس: Sciences bio-médicales et agricoles, Cell Line, Culture Media, Serum-Free -- pharmacology, Gene Expression Regulation -- drug effects, Humans, Protein Binding, Proteomics, Proto-Oncogene Proteins c-fos -- genetics, Proto-Oncogene Proteins c-fos -- metabolism, Small Ubiquitin-Related Modifier Proteins -- metabolism, Substrate Specificity, Transcription Factors -- genetics, Transcription Factors -- metabolism, Transcription, Genetic -- drug effects, Transcription, Genetic -- genetics, 2D PAGE, H2O 2, MALDI-TOF, ROS, Stress, Substrate, SUMO, Sumoylation, Ubiquitylation, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article
-
9مورد إلكتروني
المؤلفون: Hilgenberg, Lutz G W
المصدر: Molecular and cellular neurosciences; vol 19, iss 1, 97-9110; 1044-7431
مصطلحات الفهرس: Agrin: genetics, metabolism, pharmacology, Animals, Calcium Channels: physiology, Calcium Signaling: physiology, Cell Communication: physiology, Cells, Cultured, Cerebral Cortex: cytology, Electrophysiology, Epilepsy: metabolism, physiopathology, Excitatory Amino Acid Agonists: pharmacology, Genotype, Glutamic Acid: metabolism, Heterozygote, Homozygote, In Vitro Techniques, Kainic Acid: pharmacology, Mice, Neurons: cytology, physiology, Neurotoxins: pharmacology, Nicotine: pharmacology, Nicotinic Agonists: pharmacology, Phenotype, Proto-Oncogene Proteins c-fos: analysis, biosynthesis, Receptors, Glutamate: analysis, agrin, calcium channel, glutamate receptor, neurotransmitter, nicotinic receptor, animal experiment, animal model, animal tissue, article, brain cell, calcium signaling, cell differentiation, controlled study, cytotoxicity, embryo, gene induction, heterozygosity, mouse, nerve cell culture, nerve potential, neuromuscular synapse, neurotransmission, nonhuman, oncogene c fos, phenotype, priority journal, seizure, Agrin, Calcium Channels, Calcium Signaling, Cell Communication, Cerebral Cortex, Epilepsy, Excitatory Amino Acid Agonists, Glutamic Acid, Kainic Acid, Neurons, Neurotoxins, Nicotine, Nicotinic Agonists, Proto-Oncogene Proteins c-fos, Glutamate, Animalia, article
-
10مورد إلكتروني
المصدر: Hilgenberg, Lutz G W; Ho, Kathleen D; Lee, Daewoo; O'Dowd, Diane K; & Smith, Martin A. (2002). Agrin regulates neuronal responses to excitatory neurotransmitters in vitro and in vivo.. Molecular and cellular neurosciences, 19(1), 97 - 9110. UC Irvine: Retrieved from:
مصطلحات الفهرس: Medicine and Health Sciences, Agrin: genetics, metabolism, pharmacology, Animals, Calcium Channels: physiology, Calcium Signaling: physiology, Cell Communication: physiology, Cells, Cultured, Cerebral Cortex: cytology, Electrophysiology, Epilepsy: metabolism, physiopathology, Excitatory Amino Acid Agonists: pharmacology, Genotype, Glutamic Acid: metabolism, Heterozygote, Homozygote, In Vitro Techniques, Kainic Acid: pharmacology, Mice, Neurons: cytology, physiology, Neurotoxins: pharmacology, Nicotine: pharmacology, Nicotinic Agonists: pharmacology, Phenotype, Proto-Oncogene Proteins c-fos: analysis, biosynthesis, Receptors, Glutamate: analysis, agrin, calcium channel, glutamate receptor, neurotransmitter, nicotinic receptor, animal experiment, animal model, animal tissue, article, brain cell, calcium signaling, cell differentiation, controlled study, cytotoxicity, embryo, gene induction, heterozygosity, mouse, nerve cell culture, nerve potential, neuromuscular synapse, neurotransmission, nonhuman, oncogene c fos, phenotype, priority journal, seizure, Agrin, Calcium Channels, Calcium Signaling, Cell Communication, Cerebral Cortex, Epilepsy, Excitatory Amino Acid Agonists, Glutamic Acid, Kainic Acid, Neurons, Neurotoxins, Nicotine, Nicotinic Agonists, Proto-Oncogene Proteins c-fos, Glutamate, Animalia, article