مورد إلكتروني
Clinical Applications of NanoVelcro Rare-Cell Assays for Detection and Characterization of Circulating Tumor Cells.
| العنوان: | Clinical Applications of NanoVelcro Rare-Cell Assays for Detection and Characterization of Circulating Tumor Cells. |
|---|---|
| المؤلفون: | Chen, Jie-Fu |
| المصدر: | Theranostics; vol 6, iss 9, 1425-1439; 1838-7640 |
| بيانات النشر: | eScholarship, University of California 2016-01-01 |
| تفاصيل مُضافة: | Chen, Jie-Fu Zhu, Yazhen Lu, Yi-Tsung Hodara, Elisabeth Hou, Shuang Agopian, Vatche G Tomlinson, James S Posadas, Edwin M Tseng, Hsian-Rong |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Liquid biopsy of tumor through isolation of circulating tumor cells (CTCs) allows non-invasive, repetitive, and systemic sampling of disease. Although detecting and enumerating CTCs is of prognostic significance in metastatic cancer, it is conceivable that performing molecular and functional characterization on CTCs will reveal unprecedented insight into the pathogenic mechanisms driving lethal disease. Nanomaterial-embedded cancer diagnostic platforms, i.e., NanoVelcro CTC Assays represent a unique rare-cell sorting method that enables detection isolation, and characterization of CTCs in peripheral blood, providing an opportunity to noninvasively monitor disease progression in individual cancer patients. Over the past decade, a series of NanoVelcro CTC Assays has been demonstrated for exploring the full potential of CTCs as a clinical biomarker, including CTC enumeration, phenotyping, genotyping and expression profiling. In this review article, the authors will briefly introduce the development of three generations of NanoVelcro CTC Assays, and highlight the clinical applications of each generation for various types of solid cancers, including prostate cancer, pancreatic cancer, lung cancer, and melanoma. |
| مصطلحات الفهرس: | Animals, Humans, Neoplasms, Diagnostic Tests, Routine, Cell Separation, Nanomedicine, Neoplastic Cells, Circulating, Circulating tumor cell, Cancer, Lung, Prostate Cancer, Digestive Diseases, Urologic Diseases, Lung Cancer, Clinical Research, Aetiology, Detection, screening and diagnosis, 2.1 Biological and endogenous factors, 4.1 Discovery and preclinical testing of markers and technologies, 4.2 Evaluation of markers and technologies, Oncology and Carcinogenesis, article |
| URL: | |
| الإتاحة: | Open access content. Open access content public |
| ملاحظة: | application/pdf Theranostics vol 6, iss 9, 1425-1439 1838-7640 |
| أرقام أخرى: | CDLER oai:escholarship.org:ark:/13030/qt7d6368c5 qt7d6368c5 https://escholarship.org/uc/item/7d6368c5Test https://escholarship.orgTest/ 1367467866 |
| المصدر المساهم: | UC MASS DIGITIZATION From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1367467866 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |