مورد إلكتروني
INFLUENCE OF DYNAMIC LOADS DIFFERENT IN DURATION ON CHANGES IN THE ACTIVITY OF LACTATE DEHYDROGENASE ISOENZYMES IN INTERVERTEBRAL DISC CELLS
| العنوان: | INFLUENCE OF DYNAMIC LOADS DIFFERENT IN DURATION ON CHANGES IN THE ACTIVITY OF LACTATE DEHYDROGENASE ISOENZYMES IN INTERVERTEBRAL DISC CELLS |
|---|---|
| المصدر: | Slobozhanskyi herald of science and sport; Том 8, № 2 (2020); 96-108; 2311-6374 |
| بيانات النشر: | Kharkiv State Academy of Physical Culture 2020-05-04 |
| تفاصيل مُضافة: | Sak, Andrіі; Kharkiv State Academy of Physical Culture Antypova, Raisa; Kharkiv State Academy of Physical Culture |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Purpose: to determine the effect of long-term dynamic loads on changes in the activity of isoenzymes lactate dehydrogenase (LDH) in the cells of the intervertebral discs in the age aspect.Material and Methods: the study was performed on male Wistar rats of three age groups: 1, 3 and 12 months. A total of 90 animals of the experimental series and 90 animals of the control series were observed. Dynamic loads were created by running in a horizontal treadmill. Using histochemical methods, the analysis of changes in the activity of lactate dehydrogenase isoenzymes in the cells of the intervertebral discs of Wistar rats after 20- and 90-day experimental run was performed.Results: it is experimentally established that changes in the activity of lactate dehydrogenase isoenzymes depend on the age of the animals and the duration of dynamic loads. There was a decrease in the activity of LDH-1 and LDH-2 isoenzymes in the cells of the intervertebral disc, but an increase in the activity of LDH-3 and LDH-4 isoenzymes.Conclusions: the identified age features of changes in enzyme activity are proposed to be used as a histochemical test to objectively assess the degree of destructive effect of prolonged running on the fibrous cartilage of the intervertebral disc. |
| مصطلحات الفهرس: | lactate dehydrogenase, intervertebral disc, treadmill, experimental running., 611.711/616.8-009.2:001.53, info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion, Рецензована стаття |
| URL: | |
| الإتاحة: | Open access content. Open access content Copyright (c) 2020 Slobozhanskyi herald of science and sport http://creativecommons.org/licenses/by/4.0Test |
| ملاحظة: | application/pdf Slobozhanskyi herald of science and sport English |
| أرقام أخرى: | UANTU oai:ojs.journals.uran.ua:article/204192 1164602417 |
| المصدر المساهم: | NATIONAL TECH UNIV OF UKRAINE From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1164602417 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |