مورد إلكتروني

Retroperitoneal metastases in testicular cancer: role of CT measurements of residual masses in decision making for resection after chemotherapy

التفاصيل البيبلوغرافية
العنوان: Retroperitoneal metastases in testicular cancer: role of CT measurements of residual masses in decision making for resection after chemotherapy
بيانات النشر: 2000-01-01
تفاصيل مُضافة: Steyerberg, E.W. (Ewout)
Keizer, H.J.
Sleijfer, D.T. (Dirk)
Fossa, S.D. (Sophie)
Bajorin, D.F.
Gerl, A. (Arthur)
Kirkels, W.J. (Wim)
Koops, H.S.
Habbema, J.D.F. (Dik)
Wit, R. (Ronald) de
نوع الوثيقة: Electronic Resource
مستخلص: PURPOSE: To determine the relative importance of computed tomographic (CT) measurements for the prediction of histologic findings in residual masses in patients with nonseminomatous testicular cancer. MATERIALS AND METHODS: Measurements of the maximum transverse size of retroperitoneal metastases before and after chemotherapy were available in 641 patients who underwent resection after chemotherapy while their levels of tumor markers were normal. Radiologic measurements of mass size and clinical characteristics (histologic findings in primary tumor and levels of alpha-fetoprotein, human chorionic gonadotropin, and lactate dehydrogenase before chemotherapy) were related to histologic findings in the residual mass with logistic regression analysis. RESULTS: At resection, 302 patients had benign tissue, and 339 had residual tumor (mature teratomas or cancer). Tumor was more frequent in larger masses after chemotherapy but was unrelated to mass size before chemotherapy. Inclusion of the reduction in size significantly improved the logistic regression model, which included mass size after chemotherapy. This model was furth
مصطلحات الفهرس: Decision Making, Patient Care Planning, Tomography, X-Ray Computed, Area Under Curve, Carcinoma/drug therapy/pathology/secondary/surgery, Chorionic Gonadotropin/analysis, Forecasting, Humans, L-Lactate Dehydrogenase/analysis, Logistic Models, Lymphatic Metastasis, Male, Neoplasm, Residual/pathology, Odds Ratio, Prospective Studies, ROC Curve, Retroperitoneal Neoplasms/drug therapy/pathology/*secondary/surgery, Teratoma/drug therapy/pathology/secondary/surgery, Testicular Neoplasms/*pathology, Tumor Markers, Biological/analysis, alpha-Fetoproteins/analysis, info:eu-repo/semantics/article
URL: http://repub.eur.nl/pub/9359Test
الإتاحة: Open access content. Open access content
info:eu-repo/semantics/openAccess
ملاحظة: application/pdf
Radiology
English
أرقام أخرى: QGQ oai:repub.eur.nl:9359
urn:hdl:1765/9359
929960290
المصدر المساهم: ERASMUS UNIVERSITEIT ROTTERDAM
From OAIster®, provided by the OCLC Cooperative.
رقم الانضمام: edsoai.ocn929960290
قاعدة البيانات: OAIster