Major CD4 T-Cell Depletion and Immune Senescence in a Patient with Chronic Granulomatous Disease

التفاصيل البيبلوغرافية
العنوان:	Major CD4 T-Cell Depletion and Immune Senescence in a Patient with Chronic Granulomatous Disease
المؤلفون:	Adriana S. Albuquerque, Susana M. Fernandes, Rita Tendeiro, Rémi Cheynier, Margarida Lucas, Susana L. Silva, Rui M. M. Victorino, Ana E. Sousa
المصدر:	Frontiers in Immunology, Vol 8 (2017)
بيانات النشر:	Frontiers Media S.A., 2017.
سنة النشر:	2017
المجموعة:	LCC:Immunologic diseases. Allergy
مصطلحات موضوعية:	primary immunodeficiency, chronic granulomatous disease, genetic phagocytic defect, reactive oxygen species, CD4 T-cell lymphopenia, immune senescence, Immunologic diseases. Allergy, RC581-607
الوصف:	Chronic granulomatous disease (CGD) results from primary defects in phagocytic reactive oxygen species (ROS) production. T-cell evaluation is usually neglected during patients’ follow-up, although T-cell depletion has been reported in CGD through unknown mechanisms. We describe here a 36-year-old patient with X-linked CGD with severe CD4 T-cell depletion
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	1664-3224
العلاقة:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00543/fullTest; https://doaj.org/toc/1664-3224Test
DOI:	10.3389/fimmu.2017.00543
الوصول الحر:	https://doaj.org/article/9c8f501011654e078d685f5de6eca40cTest
رقم الانضمام:	edsdoj.9c8f501011654e078d685f5de6eca40c
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	16643224
DOI:	10.3389/fimmu.2017.00543