دورية أكاديمية
Micronutrient intake in relation to all-cause mortality in a prospective Danish cohort
| العنوان: | Micronutrient intake in relation to all-cause mortality in a prospective Danish cohort |
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| المؤلفون: | Nina Roswall, Anja Olsen, Jane Christensen, Louise Hansen, Lars O. Dragsted, Kim Overvad, Anne Tjønneland |
| المصدر: | Food & Nutrition Research, Vol 56, Iss 0, Pp 1-9 (2012) |
| بيانات النشر: | Swedish Nutrition Foundation, 2012. |
| سنة النشر: | 2012 |
| المجموعة: | LCC:Nutrition. Foods and food supply |
| مصطلحات موضوعية: | mortality, dietary supplements, micronutrients, prospective cohort study, vitamin C, vitamin E, folate, beta-carotene, Nutrition. Foods and food supply, TX341-641 |
| الوصف: | Background: Few studies have considered source-specific micronutrient intake in relation to mortality under the consideration that dietary and supplemental intake could exhibit different effects. Objective: To evaluate the association between intake of vitamin C, E, folate, beta-carotene from diet and supplements, and overall mortality. Furthermore, to examine effect modification by smoking, alcohol intake, and BMI and to investigate if the effect of supplement use differs with dietary micronutrient intake. Methods and Material: In a prospective cohort study of 55,453 middle-aged Danes, information regarding diet, supplement use, and lifestyle was collected through questionnaires. During follow-up, 6,767 deaths were identified and incidence rate ratios (IRRs) of mortality related to micronutrient intake were calculated using Cox proportional hazards models. Results: The present study found no effect of dietary vitamin C, E, folate, or beta-carotene in relation to mortality. In contrast, supplemental folic acid was associated with a significantly increased mortality, whereas no other micronutrient supplement was associated with mortality. Effect modification by smoking and alcohol intake, but not BMI, was suggested in relation to some dietary micronutrients. The effect of supplements did not differ in groups defined by dietary micronutrient intake. Conclusion: This study suggests no effect of dietary micronutrients in relation to overall mortality. Supplemental folic acid was found to be associated with increased mortality, but further studies are required. No other supplemental micronutrient was associated with mortality. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1654-6628 1654-661X |
| العلاقة: | http://www.foodandnutritionresearch.net/index.php/fnr/article/view/5466/21353Test; https://doaj.org/toc/1654-6628Test; https://doaj.org/toc/1654-661XTest |
| DOI: | 10.3402/fnr.v56i0.5466 |
| الوصول الحر: | https://doaj.org/article/b3f9a6b8a0d345809d6ec94aa4cfe44dTest |
| رقم الانضمام: | edsdoj.b3f9a6b8a0d345809d6ec94aa4cfe44d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16546628 1654661X |
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| DOI: | 10.3402/fnr.v56i0.5466 |