المؤلفون: Alabadi B, Civera M, Moreno-Errasquin B, Cruz-Jentoft AJ

المصدر: International Journal of Women's Health, Vol Volume 16, Pp 693-705 (2024)

مصطلحات موضوعية: postmenopausal osteoporosis, nutrition, micronutrients, bone health, dietary interventions, food components, Gynecology and obstetrics, RG1-991

الوصف: Blanca Alabadi,1,2,* Miguel Civera,1,3,* Beatriz Moreno-Errasquin,4 Alfonso J Cruz-Jentoft4 1Service of Endocrinology and Nutrition, Hospital Clinico Universitario of Valencia, Valencia, 46010, Spain; 2INCLIVA Biomedical Research Institute, Valencia, 46010, Spain; 3Department of Medicine, University of Valencia, Valencia, 46010, Spain; 4Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, 28034, Spain*These authors contributed equally to this workCorrespondence: Blanca Alabadi, Av. Blasco Ibañez, 17, Valencia, 46010, Spain, Email balabadi@incliva.esAbstract: Postmenopausal osteoporosis stands as the predominant bone disorder in the developed world, posing a significant public health challenge. Nutritional factors play a crucial role in bone health and may contribute to its prevention or treatment. Calcium and vitamin D, extensively studied with robust scientific evidence, are integral components of the non-pharmacological treatment for this disorder. Nevertheless, other less-explored nutritional elements appear to influence bone metabolism. This review provides a comprehensive summary of the latest evidence concerning the relationship between various nutrients, such as phosphorus, magnesium, vitamins, phytate, and phytoestrogens; specific foods like dairy or soy, and dietary patterns such as the Mediterranean diet with bone health and osteoporosis.Keywords: postmenopausal osteoporosis, nutrition, micronutrients, bone health, dietary interventions, food components

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/nutrition-based-support-for-osteoporosis-in-postmenopausal-women-a-rev-peer-reviewed-fulltext-article-IJWHTest; https://doaj.org/toc/1179-1411Test

الوصول الحر: https://doaj.org/article/1f2c436e859d413fbe7fd2f0bfd81ad8Test

المؤلفون: Ibrahim MO, Abuhijleh H, Tayyem R

المصدر: Cancer Management and Research, Vol Volume 15, Pp 17-30 (2023)

مصطلحات موضوعية: pancreatic cancer, macronutrients, micronutrients, and dietary pattern., Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

الوصف: Mohammed O Ibrahim,1 Haya Abuhijleh,2 Reema Tayyem2 1Department of Nutrition and Food Technology, Faculty of Agriculture, Mu’tah University, Karak, Jordan; 2Department of Human Nutrition, College of Health Sciences, QU Health, Qatar University, Doha, QatarCorrespondence: Reema Tayyem, Department of Human Nutrition, College of Health Sciences, Qatar University, Doha, 2713, Qatar, Email reema.tayyem@qu.edu.qaAbstract: This narrative review summarizes the main findings of observational studies (case-control and cohort) as well as systematic reviews and meta-analyses on the role of nutrients and dietary patterns on pancreatic cancer (PC) risk and elucidates possible mechanisms for the association between nutrients or specific food components and the risk of PC. A literature search of MEDLINE (PubMed), Google Scholar, ScienceDirect, and Scopus was performed. An extensive search of related articles published in the English language from 1985 to 2022 was carried out. Our search included macro- and micronutrient intake as well as dietary patterns associated with PC. In conclusion, the consumption of a diet high in nutrients such as sugar, fats, and red and processed meats can increase the risk of PC. Conversely, a high dietary intake of fresh fruit and vegetables and their associated nutrients like fiber, antioxidants, and polyphenols may prevent PC. Dietary patterns loaded with red and processed meats were also linked to an increased risk of PC, whereas dietary patterns rich in plant-based foods like vegetables, fruits, whole grains, and legumes were associated with a reduced risk of PC. Dietary fiber, fat-soluble vitamins, water-soluble vitamins, and minerals might also play a protective role against PC.Keywords: pancreatic cancer, macronutrients, micronutrients, dietary pattern

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/what-dietary-patterns-and-nutrients-are-associated-with-pancreatic-can-peer-reviewed-fulltext-article-CMARTest; https://doaj.org/toc/1179-1322Test

الوصول الحر: https://doaj.org/article/a89a56bf86ee4b7a818d99b14440e86fTest

المؤلفون: Nguyen AD, McMahan ZH, Volkmann ER

المصدر: Open Access Rheumatology: Research and Reviews, Vol Volume 14, Pp 309-327 (2022)

مصطلحات موضوعية: systemic sclerosis, nutrition, malnutrition, vitamins, minerals, micronutrients, Diseases of the musculoskeletal system, RC925-935

الوصف: Audrey D Nguyen,1 Zsuzsanna H McMahan,2 Elizabeth R Volkmann1 1Division of Rheumatology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; 2Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USACorrespondence: Elizabeth R Volkmann, Division of Rheumatology, Department of Medicine, David Geffen School of Medicine at UCLA, 1000 Veteran Ave, Ste 32-59, Los Angeles, CA, 90095, USA, Tel +1 310-825-2448, Email evolkmann@mednet.ucla.eduPurpose: The primary aim is to identify the micronutrient deficiencies commonly reported in SSc. The exploratory aim is to evaluate associations between micronutrient deficiencies and SSc clinical manifestations.Patient and Methods: We conducted a scoping review of all published reports on SSc and nutrition in PubMed from its inception to August 2020. Clinical trials, observational studies, meta-analyses, and case series (with ≥ 20 cases) containing data on nutritional deficiency and SSc were included. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) for reporting our findings. Two reviewers (ADN and ERV) studied the titles and abstracts of all search results with pre-specified inclusion and exclusion criteria.Results: Among 790 retrieved publications, 35 full-length articles and 3 abstracts met the inclusion/exclusion criteria. Included studies took place across multiple geographic locations and included patients with both diffuse and limited cutaneous SSc. Vitamin D deficiency was the most commonly reported deficiency described in SSc, followed by vitamin B12, vitamin B9, selenium, zinc, and iron. In addition, some small studies found deficiencies in vitamins B1, B6, C, E, and A. While some studies reported associations between specific micronutrient deficiencies and SSc disease features (eg, interstitial lung disease was commonly associated with vitamin D deficiency and elevated homocysteine [Hcy]), the evidence to support these associations was not robust.Conclusion: Micronutrient deficiencies are common in SSc and are associated with specific SSc features. Routine screening for micronutrient deficiencies may lead to early detection of malnutrition. Future studies are needed to understand how interventions to replete micronutrient deficiencies affect patient outcomes in SSc.Keywords: systemic sclerosis, micronutrient deficiency, vitamin deficiency, malnutrition, nutritional deficiency

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/micronutrient-deficiencies-in-systemic-sclerosis-a-scoping-review-peer-reviewed-fulltext-article-OARRRTest; https://doaj.org/toc/1179-156XTest

الوصول الحر: https://doaj.org/article/3296a27d60314429a2968167deb349dcTest

المؤلفون: Santonocito S, Polizzi A, Palazzo G, Indelicato F, Isola G

المصدر: Clinical, Cosmetic and Investigational Dentistry, Vol Volume 13, Pp 283-292 (2021)

مصطلحات موضوعية: periodontitis, nutrition, diet, macronutrients, micronutrients, oral health, Dentistry, RK1-715

الوصف: Simona Santonocito, Alessandro Polizzi, Giuseppe Palazzo, Francesco Indelicato, Gaetano Isola Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania, ItalyCorrespondence: Gaetano IsolaUnit of Periodontology, Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Via S. Sofia 78, Catania, 95123, ItalyTel/Fax +390953782453Email gaetano.isola@unict.itAbstract: In the last few decades, growing evidence have shown a possible impact of diet and nutrients on oral health. This review aims to describe, in the light of current knowledge, the role of diet, nutrients, and micronutrients in periodontal health and periodontal diseases. A variety of macronutrients and micronutrients could have an impact on periodontal health. The balanced intake of unprocessed complex carbohydrates, vegetable proteins, omega-3 fatty acids, minerals, and vitamins positively affects periodontal inflammation. On the other way, refined carbohydrates, non-vegetable proteins, proinflammatory saturated fatty acids and an unbalanced supply of vitamins and minerals may increase periodontal inflammation. This review will discuss the current evidence that shows how a healthy and balanced diet has anti-inflammatory and protective effects on periodontal health. Therefore, it appears that adopting a correct lifestyle and diet should be encouraged in patients with oral and periodontal disease.Keywords: periodontitis, nutrition, diet, macronutrients, micronutrients, oral health

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/dietary-factors-affecting-the-prevalence-and-impact-of-periodontal-dis-peer-reviewed-fulltext-article-CCIDETest; https://doaj.org/toc/1179-1357Test

الوصول الحر: https://doaj.org/article/9c15207ba0f7488c8cefe9133526b808Test

المؤلفون: Samad N, Dutta S, Sodunke TE, Fairuz A, Sapkota A, Miftah ZF, Jahan I, Sharma P, Abubakar AR, Rowaiye AB, Oli AN, Charan J, Islam S, Haque M

المصدر: Journal of Inflammation Research, Vol Volume 14, Pp 2091-2110 (2021)

مصطلحات موضوعية: sars-cov-2, covid-19, fat-soluble-vitamins, micronutrients, immune-response, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

الوصف: Nandeeta Samad,1 Siddhartha Dutta,2 Temitayo Eniola Sodunke,3 Adiba Fairuz,4 Ashmita Sapkota,5 Zannatul Ferdous Miftah,6 Iffat Jahan,7 Paras Sharma,8 Abdullahi Rabiu Abubakar,9 Adekunle Babajide Rowaiye,10 Angus Nnamdi Oli,10 Jaykaran Charan,2 Salequl Islam,11 Mainul Haque12 1Department of Public Health, North South University, Dhaka, 1229, Bangladesh; 2Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India; 3Department of Anatomy, University of Ilorin, Nigeria; 4Department of Pharmacy, University of Dhaka, Dhaka, Bangladesh; 5Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand; 6Department of Nutrition and Food Science, University of Dhaka, Dhaka, Bangladesh; 7Department of Physiology, Eastern Medical College, Cumilla, Bangladesh; 8Department of Pharmacognosy, BVM College of Pharmacy, Gwalior, India; 9Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Bayero University, Kano, Nigeria; 10Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria; 11Department of Microbiology, Jahangirnagar University, Savar, Dhaka, Bangladesh; 12Unit of Pharmacology, Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kuala Lumpur, MalaysiaCorrespondence: Mainul HaqueUnit of Pharmacology, Faculty of Medicine and Defence Health, Universiti Pertahanan Nasional Malaysia (National Defence University of Malaysia), Kem Perdana Sungai Besi, Kuala Lumpur, 57000, MalaysiaTel +60109265543Email runurono@gmail.comAbstract: The outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), later named COVID-19 by the World Health Organization (WHO), was initiated at Wuhan, Hubei, China, and there was a rapid spread of novel SARS-CoV-2 and the disease COVID-19 in late 2019. The entire world is now experiencing the challenge of COVID-19 infection. However, still very few evidence-based treatment options are available for the prevention and treatment of COVID-19 disease. The present review aims to summarize the publicly available information to give a comprehensive yet balanced scientific overview of all the fat-soluble vitamins concerning their role in SARS-CoV-2 virus infection. The roles of different fat-soluble vitamins and micronutrients in combating SARS-CoV-2 infection have been recently explored in several studies. There are various hypotheses to suggest their use to minimize the severity of COVID-19 infection. These vitamins are pivotal in the maintenance and modulation of innate and cell-mediated, and antibody-mediated immune responses. The data reported in recent literature demonstrate that deficiency in one or more of these vitamins compromises the patients’ immune response and makes them more vulnerable to viral infections and perhaps worse disease prognosis. Vitamins A, D, E, and K boost the body’s defense mechanism against COVID-19 infection and specifically prevent its complications such as cytokine storm and other inflammatory processes, leading to increased morbidity and mortality overemphasis. However, more detailed randomized double-blind clinical pieces of evidence are required to define the use of these supplements in preventing or reducing the severity of the COVID-19 infection.Keywords: SARS-CoV-2, COVID-19, fat-soluble vitamins, micronutrients, immune response

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/fat-soluble-vitamins-and-the-current-global-pandemic-of-covid-19-evide-peer-reviewed-fulltext-article-JIRTest; https://doaj.org/toc/1178-7031Test

الوصول الحر: https://doaj.org/article/d6083403ed1743659df397333ca95604Test

المؤلفون: Walle BM, Adekunle AO, Arowojolu AO, Dugul TT, Mebiratie AL

المصدر: Nutrition and Dietary Supplements, Vol Volume 12, Pp 237-254 (2020)

مصطلحات موضوعية: multiple micronutrients, ifa, adverse birth outcomes, pregnancy, mortalities., Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627

الوصف: Birhanie Muluken Walle,1,2 Adeyemi O Adekunle,3 Ayodele O Arowojolu,3 Tesfaye Tolessa Dugul,2 Akiloge Lake Mebiratie4 1Department of Obstetrics and Gynecology, Pan African University Life and Earth Sciences Institutes, College of Medicine, University of Ibadan, Ibadan, Nigeria; 2Department of Medical Physiology, College of Medicine and Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 3Department of Obstetrics and Gynecology, College of Medicine, University College Hospital, University of Ibadan, Ibadan, Nigeria; 4Department of Obstetrics and Gynecology, College of Health Sciences, School of Medicine, Debre Markos University, Debre Markos, EthiopiaCorrespondence: Birhanie Muluken Walle Email muluken.walle@aau.edu.etAbstract: Micronutrients are vitamins, minerals and trace elements that are used in minute doses as cofactors, antioxidants and modulators of gene transcription homeostasis. MMNs may have a role in averting or treating adverse pregnancy outcomes and maternal complications. In 2016, WHO suggested the use of iron-folic acid (IFA) rather than multiple micronutrients (MMNs) during pregnancy owing to some feared adverse outcomes like perinatal mortalities. However, this effect is debatable as such complications could be also due to genetic or environmental factors. Therefore, this appraisal should provide appropriate information and guidance to health workers, scholars and policymakers. This review includes large sample-sized studies with a special focus on developing countries like Ethiopia. The articles were selected using systematic searching with Boolean operators, advanced search techniques, snowballing and search limits. Mendeley was used as a reference management tool where the source of databases and references were PubMed, AJOL, Google Scholar, IRIS, Summon, DOAJ, Cochrane Library, Oxford Medicine Online, WHO reproductive health libraries majorly from the Hinari program. Articles from BMC, American Society for Nutrition, Lancet, Elsevier, John Wiley and Sons LTD, PLoS One, Springer and Nature Publishing Groups were also used. The results showed that there are no variations in adverse effects between MMNs and IFA. Moreover, MMNs are valuable in anemic pregnant women with lower preconception weight as it increases maternal weight and reduces low birth weight and anemia more than IFA. Therefore, MMNs may have greater health benefits than IFA for the offspring by minimizing fetal complications and the cost of their treatment, resulting from the MMN deficiency state.Keywords: multiple micronutrients, IFA, adverse birth outcomes, pregnancy, mortalities

وصف الملف: electronic resource

العلاقة: https://www.dovepress.comTest/micronutrients-deficiency-and-their-associations-with-pregnancy-outcom-peer-reviewed-article-NDS; https://doaj.org/toc/1179-1489Test

الوصول الحر: https://doaj.org/article/b4b4190e277b4550b3b470ba923f112bTest

المؤلفون: Mshanga N, Martin H, Petrucka P

المصدر: Nutrition and Dietary Supplements, Vol Volume 12, Pp 179-188 (2020)

مصطلحات موضوعية: micronutrients, pregnant women, pastoralists, dietary iron, vitamin a., tanzania, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627

الوصف: Naelijwa Mshanga,1 Haikael Martin,1 Pammla Petrucka2 1Department of Food Biotechnology and Nutrition Sciences, The Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania; 2College of Nursing, University of Saskatchewan, Saskatoon, CanadaCorrespondence: Naelijwa Mshanga Email mshangan@nm-aist.ac.tzBackground: Provision of micronutrients knowledge is important during pregnancy as it informs mothers what to eat and avoid, to ensure sufficient micronutrient absorption by the mothers and fetuses. Most studies focus on general nutrition knowledge and dietary practices, but there is minimal known about micronutrient knowledge especially in pastoral societies. Therefore, the aim of this study was to explain the current micronutrient knowledge and dietary practices of pregnant women in this unique pastoral society.Methods: This is a mixed-method study that involves focus group discussions and questionnaires in assessing the micronutrient knowledge and frequency micronutrients dietary practices of Maasai pregnant women from one week to thirty-six weeks pregnant. Chi-square test and descriptive statistics, such as percentages, frequency distribution and measures of central tendency, were used to assess socio-demographic data, micronutrients knowledge and frequency of micronutrients dietary practices and the comparison between knowledge and dietary practices, while inductive thematic content analysis was used to analyze qualitative data.Results: In total, 140 questionnaires were completed with a response rate of 100% and 32 participants drawn from this group attended one of four focus group discussions. The study found that most participants had good knowledge of dietary iron, while less than a quarter (24.3%) had good knowledge of vitamin A. Moreover, there was a statistical significance difference (P=0.043) between knowledge and dietary practices. Low dietary micronutrient intake was primarily due to cultural restrictions, prohibition in cultivating and unavailability of micronutrients rich foods in this geographical area.Conclusion: The majority of the study participants had good knowledge of iron compared to vitamin A; however, they do not translate the knowledge in dietary practices. Therefore, the Government of Tanzania through Ministry of Education and Health should introduce different interventions to increase micronutrients knowledge and practices in pastoral societies.Keywords: micronutrients, pregnant women, pastoralists, dietary iron, vitamin A, Tanzania

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/knowledge-and-dietary-practices-on-vitamin-a-and-iron-among-maasai-pre-peer-reviewed-article-NDSTest; https://doaj.org/toc/1179-1489Test

الوصول الحر: https://doaj.org/article/4e03e524558d4df6a41caefbe805f42dTest

المؤلفون: Umeakunne K, Hibbert JM

المصدر: Nutrition and Dietary Supplements, Vol Volume 11, Pp 9-17 (2019)

مصطلحات موضوعية: Macronutrients, micronutrients, inflammation, Vaso-occlusive crisis (VOC), Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627

الوصف: Kayellen Umeakunne,1 Jacqueline M Hibbert21Clinical Research Center, Bio-nutrition Core, Morehouse School of Medicine, Atlanta, GA, USA; 2Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, GA, USAAbstract: A cure for sickle cell anemia (SCA) is not available to all who have inherited this devastating genetically inherited disease. However, increasing knowledge that nutritional problems are fundamental to the severity of the disease, has produced interest in promoting dietary supplementation for treating these patients. This review seeks to emphasize the understanding that both children and adults with sickle cell disease require much higher energy and protein consumption (more macronutrient intake) than healthy individuals and tend to suffer from undernutrition if energy intake is consistently low. Shortages may also exist for micronutrients, eg, Glutathione, which has both anti-inflammatory and anti-oxidant properties. Both chronic inflammation and oxidant stress are central issues for increased sickle cell disease severity. In conclusion, dedicating more effort and resources to establishing recommended dietary reference intakes (DRIs)/recommended dietary allowances (RDAs) for SCA patients is essential, and nutritional intervention should be included as an adjunct treatment in tandem with standard practice.Keywords: macronutrients, micronutrients, inflammation, vaso-occlusive crisis (VOC)

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/nutrition-in-sickle-cell-disease-recent-insights-peer-reviewed-article-NDSTest; https://doaj.org/toc/1179-1489Test

الوصول الحر: https://doaj.org/article/2d8040dc429542b2b0c49ff75b7e60f8Test

المؤلفون: Serena TE, Yaakov RA, DeLegge M, Mayhugh TA, Moore S

المصدر: Chronic Wound Care Management and Research, Vol Volume 5, Pp 5-9 (2018)

مصطلحات موضوعية: Wound care, chronic wounds, parenteral nutrition, micronutrients, macronutrients, wound healing, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

الوصف: Thomas E Serena,1 Raphael A Yaakov,1 Mark DeLegge,2 Tim A Mayhugh,1 Sarah Moore1 1SerenaGroup, Cambridge, MA, USA; 2Nutritional Healing LLC, Nashville, TN, USA Abstract: Chronic ulcers continue to pose a significant clinical and economic burden for both patients and wound care practitioners. Despite good standard of care (SOC), many wounds fail to heal. Wound healing requires a complex cascade of physiologic and immunologic processes as well as proper nutrition. An adequate balance of macro- and micronutrients is important to support the cellular activities that are necessary for repairing and remodeling of tissue. Despite being well documented in a number of clinical studies there continues to be a gap in recognizing nutritional deficits as well as appropriate clinical interventions in patients with chronic wounds. Effective management of malnutrition in patients with chronic wounds requires collaboration among multiple clinical disciplines. A holistic nutritional management approach may yield both clinical and economic benefits. Keywords: wound care, chronic wounds, parenteral nutrition, micronutrients, macronutrients, wound healing, nutrition management, malnutrition, nutrition assessment

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/nutrition-in-patients-with-chronic-non-healing-ulcers-a-paradigm-shift-peer-reviewed-article-CWCMRTest; https://doaj.org/toc/2324-481XTest

الوصول الحر: https://doaj.org/article/2c7128fb4ca2439abb93eee58653771eTest

المؤلفون: Sneij A, Campa A, Baum MK

المصدر: Nutrition and Dietary Supplements, Vol 2016, Iss Issue 1, Pp 21-39 (2016)

مصطلحات موضوعية: HIV, micronutrients, probiotics, antiretroviral therapy, randomized clinical trials, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627

الوصف: Alicia Sneij, Adriana Campa, Marianna K Baum Stempel College of Public Health and Social Work, Florida International University, Modesto Maidique Campus, Miami, FL, USA Background: Nutritional deficiencies are widespread in people living with HIV (PLWH), prior to the antiretroviral treatment (ART). Nutrient deficiencies and other nutrition-related conditions, however, have been identified in patients receiving ART. Trials of nutritional supplementation have been conducted to alleviate these nutritional conditions and improve or reverse nutrition-related outcomes. This review aims to evaluate the benefits of supplementation, its unintended adverse effects, and the difference in approach and focus, research design, formulations, and outcomes between those randomized clinical trials (RCTs) conducted before and after the initiation of ART. Methods: An evidence-based systematic review of the literature was conducted using electronic databases and the resources of the Florida International University Research Library. Forty-two RCTs were selected for review, and their design and outcomes were compared and contrasted conceptually and in the form of tables. Results: Most of the RCTs (n=31) were conducted before the advent of ART, and their aims were delaying disease progression, reversing malnutrition, and improving pregnancy outcomes in women and infants infected with HIV. The RCTs conducted with coadministration of ART were fewer (n=11), with relative smaller sample size, of shorter duration, and mainly focused on preventing or ameliorating the nutrition-related conditions generated by the chronic infection, its treatment, and the aging of PLWH. Conclusion: As ART is becoming more accessible worldwide, and people are living longer with the disease, more longitudinal trials of nutritional interventions with larger sample sizes are needed to study the nutritional consequences and potential treatments for PLWH. Keywords: HIV, antiretroviral therapy, micronutrients, probiotics, AIDS, randomization, clinical trial

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/review-of-randomized-controlled-trials-of-nutritional-supplementation--peer-reviewed-article-NDSTest; https://doaj.org/toc/1179-1489Test

الوصول الحر: https://doaj.org/article/83eb00cabf874594be4805484feb20d5Test