دورية أكاديمية
SOME RESULT OF QUALITY PARAMETERS OF 'GARDI' TRANSDERMAL PATCH
| العنوان: | SOME RESULT OF QUALITY PARAMETERS OF 'GARDI' TRANSDERMAL PATCH |
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| المؤلفون: | Erdenechimeg Ch, Uuganbayar B, Dejidmaa B, Chimedragchaa Ch, Munkhzul G |
| المصدر: | Proceedings of the Mongolian Academy of Sciences, Vol 57, Iss 4, Pp 44-49 (2018) |
| بيانات النشر: | Mongolian Academy of Sciences, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Science LCC:Social Sciences |
| مصطلحات موضوعية: | Gardi patch, transdermal patch, standardization, quality parameters, high performance liquid chromatography, aconitine, Science, Social Sciences |
| الوصف: | The aim of this study was to conduct standardization study and determine quality parameters of “Gardi” transdermal patch. We used “Gardi” transdermal patch consists of extract of radix Aconitum Kusnezoffii, extract of Terminalia chebula, extract of Saussurea lappa L., extract of Acorus calamus L. and Musk of Musk deer. We used some biologically active compounds of the transdermal patch were revealed by TLC. And main biologically active compounds content of the transdermal patch were determined by spectrophotometric methods. The moisture, average weight and parameters of microbiology were determined by Mongolian National First Pharmacopoeia methods. The transdermal patch was light brown colour, unusual smell and rectangular shape. We determined aconitine, costunolide and gallic acid in “Gardi” transdermal patch by TLC. The retention time of aconitine was 63.04±0.2 minutes and amount was 0.169±0.009% by HPLC.The polyphenolic compounds by spectrophotometer method using Folin-Chiocalto reagent as 0.567±0.043%. Quality and safety parameters of “Gardi” transdermal patch determined as: moisture 27.28±0.65 %, average weight 3.969±0.196 g, thickness 0.83±0.2 mm, total bacteria 1х103, mould, Escherichia coli, Salmonella, Pseudomonas aeruginosa, Staphylococcus aureus and Enterobacter were not detected in “Gardi” transdermal patch. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Mongolian Russian |
| تدمد: | 2310-4716 2312-2994 |
| العلاقة: | https://www.mongoliajol.info/index.php/PMAS/article/view/922Test; https://doaj.org/toc/2310-4716Test; https://doaj.org/toc/2312-2994Test |
| DOI: | 10.5564/pmas.v57i4.922 |
| الوصول الحر: | https://doaj.org/article/2b9ac5fee75943cda2a3b2494e41d222Test |
| رقم الانضمام: | edsdoj.2b9ac5fee75943cda2a3b2494e41d222 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23104716 23122994 |
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| DOI: | 10.5564/pmas.v57i4.922 |