دورية أكاديمية
Antiproliferative effects of Camellia sinensis, Frangula alnus and Rosmarinus officinalis
| العنوان: | Antiproliferative effects of Camellia sinensis, Frangula alnus and Rosmarinus officinalis |
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| المؤلفون: | Cenić-Milošević Desanka, Tambur Z., Ivančajić S., Bokonjić D., Čuković Anika, Stanojković Tatjana, Grozdanić Nađa, Kulišić Z., Juranić Zorica |
| المصدر: | Archives of Biological Sciences, Vol 65, Iss 3, Pp 885-891 (2013) |
| بيانات النشر: | University of Belgrade, University of Novi Sad, 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Biology (General) |
| مصطلحات موضوعية: | Antiproliferative effect, Camellia sinensis, Frangula alnus, Rosmarinus officinalis, Biology (General), QH301-705.5 |
| الوصف: | The use of medicinal plants is becoming increasingly appreciated in suppressing cancer growth and cancer prevention. In this study the antiproliferative effects of the water extracts of previously obtained ethanolic dry extracts of three different medicinal plants (Camellia sinensis, Frangula alnus from two different places and Rosmarinus officinalis) using cell lines derived from human cervix adenocarcinoma (Hela cells) were investigated. The extract of Camellia sinensis exhibited significant cytotoxic effect against Hela cells (IC50 40.88 μg/ml). Screening in Hela cells revealed a moderate cytotoxic effect (IC50 80.26μg/ml) of the extract of Rosmarinus officinalis, a mild cytotoxic effect (IC50 148.05 μg/ml) of the extract of Frangula alnus (originating in Bosnia), and the extract of Frangula alnus (originating in Serbia) did not show active cytotoxicity (IC50 > 200 μg/ml). The best antiproliferative properties are those of Camellia sinensis, followed by Rosmarinus officinalis, and the least effective was Frangula alnus. As regards geographic origin, the Frangula alnus from Bosnia possessed better antiproliferative effects than Frangula alnus from Serbia. [Projekat Ministarstva nauke Republike Srbije, br. 34021 i br. 175011] |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0354-4664 1821-4339 |
| العلاقة: | https://doaj.org/toc/0354-4664Test; https://doaj.org/toc/1821-4339Test |
| DOI: | 10.2298/ABS1303885M |
| الوصول الحر: | https://doaj.org/article/e7dec2d97c4f4e9185670510f97b1152Test |
| رقم الانضمام: | edsdoj.7dec2d97c4f4e9185670510f97b1152 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 03544664 18214339 |
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| DOI: | 10.2298/ABS1303885M |