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1دورية أكاديمية
المؤلفون: Pedro Tadao Hamamoto Filho, Marco Antônio Zanini, Fabio Pires Botta, Marianna Vaz Rodrigues, Rodrigo Bazan, Luiz Carlos Vulcano, Germano Francisco Biondi
المصدر: Acta Cirúrgica Brasileira, Vol 30, Iss 12, Pp 819-823 (2015)
مصطلحات موضوعية: Neurocysticercosis, Hydrocephalus, Magnetic Resonance Imaging, Cerebrospinal Fluid, Rats., Surgery, RD1-811
الوصف: ABSTRACT PURPOSE: To develop an experimental model of neurocysticercosis-induced hydrocephalus METHODS: There were used 17 rats. Ten animals were inoculated with Taenia crassiceps cysts into the subarachnoid. Five animals were injected with 0.1ml of 25% kaolin (a standard solution for the development of experimental hydrocephalus) and two animals were injected with saline. Magnetic resonance imaging (MRI) was used to evaluate enlargement of the ventricles after one or three months of inoculation. Volumetric study was used to quantify the ventricle enlargement. RESULTS: Seven of the 10 animals in the cyst group developed hydrocephalus, two of them within one month and five within three months after inoculation. Three of the five animals in the kaolin group had hydrocephalus and none in the saline group. Ventricle volumes were significantly higher in the 3-months MRI cyst subgroup than in the 1-month cyst subgroup. Differences between cyst subgroups and kaolin group did not reach statistical significance. CONCLUSION: The developed model may reproduce the human condition of neurocysticercosis-related hydrocephalus, which exhibits a slowly progressive chronic course.
وصف الملف: electronic resource
العلاقة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015001200819&tlng=enTest; http://www.scielo.br/pdf/acb/v30n12/1678-2674-acb-30-12-00819.pdfTest; https://doaj.org/toc/0102-8650Test
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2دورية أكاديمية
المؤلفون: Samuel Caputo de Castro, Hélio Rubens Machado, Carlos Henrique Rocha Catalão, Betina Aisengart de Siqueira, Ana Leda Bertoncini Simões, João-José Lachat, Luiza da Silva Lopes
المصدر: Acta Cirúrgica Brasileira, Vol 27, Iss 11, Pp 768-772 (2012)
مصطلحات موضوعية: Hidrocefalia, Imagem por Ressonância Magnética, Ratos, Hydrocephalus, Magnetic Resonance Imaging, Rats, Surgery, RD1-811
الوصف: PURPOSE: To investigate the accuracy of 1.0T Magnetic Resonance Imaging (MRI) to measure the ventricular size in experimental hydrocephalus in pup rats. METHODS: Wistar rats were subjected to hydrocephalus by intracisternal injection of 20% kaolin (n=13). Ten rats remained uninjected to be used as controls. At the endpoint of experiment animals were submitted to MRI of brain and killed. The ventricular size was assessed using three measures: ventricular ratio (VR), the cortical thickness (Cx) and the ventricles area (VA), performed on photographs of anatomical sections and MRI. RESULTS: The images obtained through MR present enough quality to show the lateral ventricular cavities but not to demonstrate the difference between the cortex and the white matter, as well as the details of the deep structures of the brain. There were no statistically differences between the measures on anatomical sections and MRI of VR and Cx (p=0.9946 and p=0.5992, respectively). There was difference between VA measured on anatomical sections and MRI (pOBJETIVO: Investigar a fidelidade das Imagens de Ressonância Magnética de 1,0T no estudo do tamanho ventricular na hidrocefalia experimental em ratos jovens. MÉTODOS: Ratos Wistar foram submetidos à hidrocefalia através da injeção intracisternal de caulim 20%. Dez animais permaneceram sem injeção para uso como controles. Ao final do experimento, os animais foram submetidos à Ressonância magnética de encéfalo e sacrificados. O tamanho ventricular foi avaliado por três medidas: razão ventricular (VR), espessura cortical (Cx) e área ventricular (VA), tomadas em fotografias das secções anatômicas e nas imagens de ressonância magnética (RM). RESULTADOS: As imagens por RM apresentaram qualidade suficiente para individualizar os ventriculos laterais, mas a distinção entre córtex e substância branca, bem como detalhamento das estruturas profundas do encéfalo não foram possíveis. Quando comparadas as medidas em seções anatômicas e RM, não houve diferença estatística entre as médias de razão ventricular e espessura cortical (p=0,9946 e p=0,5992, respectivamente). Houve diferença da área ventricular comparando-se as secções anatômicas e ressonância magnética (p
وصف الملف: electronic resource
العلاقة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012001100005Test; https://doaj.org/toc/0102-8650Test; https://doaj.org/toc/1678-2674Test
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3دورية أكاديمية
المؤلفون: Samuel Caputo de Castro, Hélio Rubens Machado, Carlos Henrique Rocha Catalão, Betina Aisengart de Siqueira, Ana Leda Bertoncini Simões, João-José Lachat, Luiza da Silva Lopes
المصدر: Acta Cirúrgica Brasileira, Vol 27, Iss 11, Pp 768-772 (2012)
مصطلحات موضوعية: Hydrocephalus, Magnetic Resonance Imaging, Rats, Surgery, RD1-811
الوصف: PURPOSE: To investigate the accuracy of 1.0T Magnetic Resonance Imaging (MRI) to measure the ventricular size in experimental hydrocephalus in pup rats. METHODS: Wistar rats were subjected to hydrocephalus by intracisternal injection of 20% kaolin (n=13). Ten rats remained uninjected to be used as controls. At the endpoint of experiment animals were submitted to MRI of brain and killed. The ventricular size was assessed using three measures: ventricular ratio (VR), the cortical thickness (Cx) and the ventricles area (VA), performed on photographs of anatomical sections and MRI. RESULTS: The images obtained through MR present enough quality to show the lateral ventricular cavities but not to demonstrate the difference between the cortex and the white matter, as well as the details of the deep structures of the brain. There were no statistically differences between the measures on anatomical sections and MRI of VR and Cx (p=0.9946 and p=0.5992, respectively). There was difference between VA measured on anatomical sections and MRI (p
وصف الملف: electronic resource
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4دورية أكاديمية
المؤلفون: Edvaldo José Rodrigues Cardoso, João José Lachat, Luiza Silva Lopes, Antonio Carlos dos Santos, Benedicto Oscar Colli
المصدر: Acta Cirúrgica Brasileira, Vol 26, Pp 8-14 (2011)
مصطلحات موضوعية: Hidrocefalia, Corpo Caloso, Bainha de Mielina, Cães, Hydrocephalus, Corpus Callosum, Myelin Sheath, Dogs, Surgery, RD1-811
الوصف: PURPOSE: To analyze the ventricular enlargement and myelination of the corpus callosum in adult dogs after four and eight weeks of kaolin-induction of hydrocephalus. METHODS: 36 dogs were randomly divided into 3 groups: 1 - without hydrocephalus, 2 - kaolin-induction of hydrocephalus until the fourth week, and 3 - kaolin-induction of hydrocephalus until the eighth week. Ventricular ratios and volumes were calculated using magnetic resonance images, and myelination of the corpus callosum were histologically evaluated using solocromo-cianin stain. RESULTS: Radiological hydrocephalus was observed in 93.75% and overall mortality was 38.4%. Ventricular volumes and ratios were higher in groups 2 and 3 compared to group 1 and similar when measures in the fourth and eighth weeks were compared in the group 3. Indices of luminescence in the knee and in the splenium of the corpus callosum were higher in group 2 than in group 1 indicating that there was loss of myelin in group 2, and similar in groups 1 and 3, showing a tendency to remyelination after 8 weeks. CONCLUSION: The corpus callosum of dogs with kaolin-induced hydrocephalus responds with demyelination of the knee and splenium by the fourth week with a tendency to remyelination by the eighth week.OBJETIVO: Analisar a dilatação ventricular e a mielinização do corpo caloso em cães adultos após quatro e oito semanas da indução de hidrocefalia por caulin. MÉTODOS: 36 cães foram aleatoriamente divididos em 3 grupos: 1- sem hidrocefalia, 2- quatro semanas de hidrocefalia induzida por caulin, 3- oito semanas de hidrocefalia induzida por caulin. As razões e volumes ventriculares foram calculados utilizando imagens de ressonância magnética, e, a mielinização do corpo caloso por estudo histológico (coloração com solocromo- cianina). RESULTADOS: Hidrocefalia foi observada radiologicamente em 93,75% e a mortalidade global foi de 38,4%. Os volumes e as razões ventriculares foram maiores nos grupos 2 e 3 em relação ao grupo 1 e semelhantes nas quarta e oitava semanas no grupo 3. Índices de luminescência no joelho e no esplênio do corpo caloso foram maiores no grupo 2 em relação ao grupo 1, indicando que houve perda de mielina no grupo 2, e semelhantes nos grupos 1 e 3, mostrando uma tendência à remielinização em torno de 8 semanas. CONCLUSÃO: O corpo caloso de cães com hidrocefalia induzida por caulin responde com desmielinização no joelho e esplênio em torno de quatro semanas com tendência à remielinização em torno da oitava semana.
وصف الملف: electronic resource
العلاقة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502011000800003Test; https://doaj.org/toc/0102-8650Test; https://doaj.org/toc/1678-2674Test
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5دورية أكاديمية
المصدر: Acta Cirúrgica Brasileira, Vol 26, Pp 133-140 (2011)
مصطلحات موضوعية: Hidrocefalia, Neuroendoscopia, Septo Pelúcido, Anatomia, Hydrocephalus, Neuroendoscopy, Septum Pellucidum, Anatomy, Surgery, RD1-811
الوصف: PURPOSE: Verify the presence of the rostral lamina of the corpus callosum, and set parameters for neuroendoscopy. METHODS: Relationship of the floor of the frontal horn of lateral ventricle and the hypothalamic-septal region were studied after sagittal and axial sections of the brains. Measurements were compared using F and Student t tests. The correlations between anterior-posterior diameter of the interventricular foramen / anterior-posterior diameter of the fornix column, and between anterior-posterior diameter of the interventricular foramen / length of the rostral lamina were performed by Pearson index test. RESULTS: There was no statistically significant difference in measurements performed in both hemispheres (pOBJETIVO: Verificar a presença da lâmina rostral do corpo caloso e padronizar parâmetros para a realização de neuroendoscopia. MÉTODOS: A relação do assoalho do corno frontal do ventrículo lateral e a região hipotálamo-septal lateral foi estudada através de secções sagitais e axiais dos cérebros. As medidas foram comparadas utilizando os testes F e t-Student. As correlações entre diâmetro ântero-posterior do forame interventricular / diâmetro ântero-posterior da coluna do fornix, e entre o diâmetro ântero-posterior do forame interventricular / comprimento da lâmina rostral foram estudadas pelo teste de Pearson. RESULTADOS: Não houve diferença estatisticamente significante nas medidas realizadas em ambos hemisférios (p
وصف الملف: electronic resource
العلاقة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502011000800025Test; https://doaj.org/toc/0102-8650Test; https://doaj.org/toc/1678-2674Test
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6دورية أكاديمية
المؤلفون: Lopes Luiza da Silva, Machado Hélio Rubens, Lachat João-José
المصدر: Acta Cirúrgica Brasileira, Vol 18, Iss suppl.5, Pp 10-14 (2003)
مصطلحات موضوعية: Corpus callosum, Hydrocephalus, Myelin, Wistar rat, Development, Surgery, RD1-811
الوصف: PURPOSE: Hydrocephalus causes countless cerebral damages, especially on the structures around the ventricles. Hydrocephalic children present deficiencies in the nonverbal skills more than in the verbal skills, and not always revertible with an early treatment. As the corpus callosum has an important role in the nonverbal acquisition it is possible that the injuries in this structure are responsible for the cognitive dysfunctions of these children. This present study tries to establish the alterations caused by hydrocephalus on the corpus callosum of developing Wistar rats, induced by intracisternal injection of kaolin. METHODS : Seven, fourteen and twenty one days after the injection, the animals were killed, and the corpus callosum was dissected and prepared for the study of the axonal fibers. RESULTS AND CONCLUSION: The seven-day old rats in hydrocephalus development presented a delay in myelination in relation to the control rats. With the fourteen-day old rats in hydrocephalus development the corpus callosum showed a recovery of myelin, but with the twenty one-day old rats in hydrocephalus development the axonal fibers were damaged and reduced in number.
وصف الملف: electronic resource
