دورية أكاديمية
Direct Thrombus Imaging in Stroke
| العنوان: | Direct Thrombus Imaging in Stroke |
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| المؤلفون: | Kim, Jongseong, Park, Jung E., Nahrendorf, Matthias, Kim, Dong-Eog |
| المصدر: | Kim, Jongseong, Jung E. Park, Matthias Nahrendorf, and Dong-Eog Kim. 2016. “Direct Thrombus Imaging in Stroke.” Journal of Stroke 18 (3): 286-296. doi:10.5853/jos.2016.00906. http://dx.doi.org/10.5853/jos.2016.00906Test. |
| بيانات النشر: | Korean Stroke Society, 2016. |
| سنة النشر: | 2016 |
| المجموعة: | HMS Scholarly Articles |
| مصطلحات موضوعية: | Acute stroke, Direct thrombus imaging, Positron-emission tomography, X-ray Computed Tomography, Magnetic resonance imaging, Molecular imaging |
| الوصف: | There is an emergent need for imaging methods to better triage patients with acute stroke for tissue-plasminogen activator (tPA)-mediated thrombolysis or endovascular clot retrieval by directly visualizing the size and distribution of cerebral thromboemboli. Currently, magnetic resonance (MR) or computed tomography (CT) angiography visualizes the obstruction of blood flow within the vessel lumen rather than the thrombus itself. The present visualization method, which relies on observation of the dense artery sign (the appearance of cerebral thrombi on a non-enhanced CT), suffers from low sensitivity. When translated into the clinical setting, direct thrombus imaging is likely to enable individualized acute stroke therapy by allowing clinicians to detect the thrombus with high sensitivity, assess the size and nature of the thrombus more precisely, serially monitor the therapeutic effects of thrombolysis, and detect post-treatment recurrence. This review is intended to provide recent updates on stroke-related direct thrombus imaging using MR imaging, positron emission tomography, or CT. |
| نوع الوثيقة: | Journal Article |
| اللغة: | English |
| تدمد: | 2287-6391 |
| العلاقة: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066439/pdfTest/; Journal of Stroke |
| DOI: | 10.5853/jos.2016.00906 |
| الوصول الحر: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:29408135Test |
| حقوق: | open URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAATest |
| رقم الانضمام: | edshld.1.29408135 |
| قاعدة البيانات: | Digital Access to Scholarship at Harvard (DASH) |
Full Text Finder | تدمد: | 22876391 |
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| DOI: | 10.5853/jos.2016.00906 |