المؤلفون: Pistenmaa, Carrie L., Nardelli, P., Ash, S.Y., Come, C.E., Diaz, A.A., Rahaghi, F.N., Barr, R.G., Young, K.A., Kinney, G.L., Simmons, J.P., Wade, R.C., Wells, J.M., Hokanson, J.E., Washko, G.R., San José Estépar, R., COPDGene Investigators, Pistenmaa, C L, San José, Estépar R

المصدر: CHEST; Aug2021, Vol. 160 Issue 2, p470-480, 11p

مصطلحات موضوعية: LUNGS, LUNG volume, ANIMAL development, DISEASE progression, PULMONARY circulation

مستخلص: Background: Pulmonary endothelial damage has been shown to precede the development of emphysema in animals, and vascular changes in humans have been observed in COPD and emphysema.Research Question: Is intraparenchymal vascular pruning associated with longitudinal progression of emphysema on CT imaging or decline in lung function over 5 years?Study Design and Methods: The Genetic Epidemiology of COPD Study enrolled ever smokers with and without COPD from 2008 through 2011. The percentage of emphysema-like lung, or "percent emphysema," was assessed at baseline and after 5 years on noncontrast CT imaging as the percentage of lung voxels < -950 Hounsfield units. An automated CT imaging-based tool assessed and classified intrapulmonary arteries and veins. Spirometry measures are postbronchodilator. Pulmonary arterial pruning was defined as a lower ratio of small artery volume (< 5 mm2 cross-sectional area) to total lung artery volume. Mixed linear models included demographics, anthropomorphics, smoking, and COPD, with emphysema models also adjusting for CT imaging scanner and lung function models adjusting for clinical center and baseline percent emphysema.Results: At baseline, the 4,227 participants were 60 ± 9 years of age, 50% were women, 28% were Black, 47% were current smokers, and 41% had COPD. Median percent emphysema was 2.1 (interquartile range, 0.6-6.3) and progressed 0.24 percentage points/y (95% CI, 0.22-0.26 percentage points/y) over 5.6 years. Mean FEV1 to FVC ratio was 68.5 ± 14.2% and declined 0.26%/y (95% CI, -0.30 to -0.23%/y). Greater pulmonary arterial pruning was associated with more rapid progression of percent emphysema (0.11 percentage points/y per 1-SD increase in arterial pruning; 95% CI, 0.09-0.16 percentage points/y), including after adjusting for baseline percent emphysema and FEV1. Arterial pruning also was associated with a faster decline in FEV1 to FVC ratio (-0.04%/y per 1-SD increase in arterial pruning; 95% CI, -0.008 to -0.001%/y).Interpretation: Pulmonary arterial pruning was associated with faster progression of percent emphysema and more rapid decline in FEV1 to FVC ratio over 5 years in ever smokers, suggesting that pulmonary vascular differences may be relevant in disease progression.Trial Registry: ClinicalTrials.gov; No.: NCT00608764; URL: www.clinicaltrials.gov. [ABSTRACT FROM AUTHOR]

: Copyright of CHEST is the property of American College of Chest Physicians and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Cope, T. C., Housley, S. N., Nardelli, P., Carrasco, D. I., Powers, R. K.

المصدر: Proceedings of the Physiological Society; 2019, Issue 43, p72P-74P, 3p

مصطلحات موضوعية: MUSCLES, RATS, PATHOLOGICAL physiology

المؤلفون: Pieri, M, Ortalda, A, Ajello, S, Altizio, S, Nardelli, P, Scandroglio, AM

المصدر: European Heart Journal: Acute Cardiovascular Care; 2022 Supplement, Vol. 11, p1-1, 1p

المؤلفون: Rahmatollahi, G., Perez Guirao, M.D., Nardelli, P., de Abreu, G.

المصدر: 2009 6th Workshop on Positioning, Navigation & Communication; 2009, p125-128, 4p

المؤلفون: Eusebi, A. L., Nardelli, P., Gatti, G., Battistoni, P., Cecchi, F.

المصدر: Water Science & Technology; 2009, Vol. 60 Issue 4, p1041-1048, 8p, 1 Diagram, 6 Charts, 6 Graphs

مصطلحات موضوعية: MASS (Serials control system), CONSUMPTION (Economics), NONMETALS, ENERGY consumption, POWER resources, WINE making -- Environmental aspects, ENERGY management

مستخلص: The paper deals with the results obtained as nitrogen removal and energy savings in a wastewater treatment plant located in the Province of Trento where the vineyards grow on about 1,500 ha (19% of total vineyards of the Province). In the plant the municipal and pre-treated winery wastewater were co-treated. The optimal effluent quality and the reduction of energy consumption were achieved changing the total oxidation process to an alternate cycles (AC) one and applying a remote control system for three months. The characterization of the influent highlighted a remarkable variability of the mass loads mainly determined by the cyclic winemaking periods. The AC application allowed the system to cope with the intense variations of influent nitrogen loadings and to obtain a stable quality of the effluent with an average TN concentration less than 10mgNL^-1. The nitrogen loading rate (NLR) up to 0.227 Kg TNm^-3 d^-1 was tolerated by the elevated AC control level device to assure successful denitrification performances (from 70% to 90%) also in conditions of COD/TN lower than 7. Comparing the AC with the pre AC conditions, a total energy saving in the range of 13-23% was estimated. Moreover, the specific energy consumptions were reduced to 59% despite the increment of the influent mass loadings. [ABSTRACT FROM AUTHOR]

: Copyright of Water Science & Technology is the property of IWA Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Nardelli, P., Gatti, G., Cecchi, F., Battistoni, E. M.

المصدر: Water Science & Technology; 2008, Vol. 58 Issue 4, p831-838, 8p, 4 Charts, 7 Graphs

مصطلحات موضوعية: WASTEWATER treatment, AUTOMATION, SEWAGE disposal plants, SEWAGE purification, DENITRIFICATION, ENERGY policy

مستخلص: The paper deals with the real application of a strategy, based on process control automation and remote on-line supervision, for the wastewater treatment in a piedmont. Three existing small wastewater treatment plants were selected to be upgraded and to be included into a network remotely supervised. Further, the potentialities of the process control automation were enhanced by the appropriate upgrading of the whole plant. A consolidated alternating nitrification and denitrification process was applied for the biological treatment. The selected plants well represent the area of Autonomous Province of Trento because they are characterized by remarkable seasonal fluctuation. After five months of experimentation data processed show the real stable high quality of the treated effluent in terms of total nitrogen content. Moreover, the power requirements are significantly reduced according the correct energy policy. The performances of the new biological process applied and the economical balance, put in evidence the gain by chosing the AC technology for upgrading small WWTPs. [ABSTRACT FROM AUTHOR]

: Copyright of Water Science & Technology is the property of IWA Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Andreottola, G., Cadonna, M., Foladori, P., Gatti, G., Lorenzi, F., Nardelli, P.

المصدر: Water Science & Technology; 2007, Vol. 56 Issue 2, p111-120, 10p, 1 Diagram, 3 Charts, 2 Graphs

مصطلحات موضوعية: WINE making -- Environmental aspects, INDUSTRIAL waste management, HEAVY metals removal (Sewage purification), WASTEWATER treatment, CHELATES, TRIAZINES, COPPER & the environment, ZINC & the environment

مستخلص: In most cases of winery effluent, the heavy metal content, especially zinc (Zn) and copper (Cu), does not meet the limits for the discharge as imposed by the most restrictive regulations at international level (0.4 mgCu/L and 1.0mgZn/L in the Italian regulations). An alternative for the reduction of Cu and Zn is the on-site pre-treatment of wastewater at the winery in order to meet the limits for the discharge into the public sewerage. The purpose of this study is to evaluate the effectiveness of a pre-treatment based on chemical precipitation with chelating agents (TMT: 2,4,6-trimercaptotriazine), for the reduction of Cu and Zn from raw winery wastewater. The chemical precipitation was optimised at lab-scale through jar tests in order to evaluate the optimal dosages. An average dosage equal to 0.84 mL of TMT (15%) for 1mg of Cu removed was estimated. Furthermore, the efficiency of the on-site chemical pre-treatment was investigated at pilot scale. The results confirmed the feasibility of using TMT treatment for the reduction of Cu and Zn in order to meet the limits for discharge into the sewerage. Contextually to the removal of heavy metals, the chemical pre-treatment allowed us to obtain the reduction of particulate COD and TSS. Finally, the costs for the operation and the management of the on-site pre-treatment were evaluated. [ABSTRACT FROM AUTHOR]

: Copyright of Water Science & Technology is the property of IWA Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Turi, S, Nardelli, P, Landoni, G

المصدر: Annals of Cardiac Anaesthesia; Jul-Sep2020, Vol. 23 Issue 3, p258-259, 2p

مستخلص: Since the first cases of a different type of pneumonia in Wuhan, China in December 2019, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected more than 6.3 million people, with 376,294 confirmed deaths in 185 different countries as of June 1, 2020.[[1]] As other viruses from the Coronaviridae family, SARS-CoV-2 infection entails a systemic syndrome (COVID-19) in which respiratory symptoms represent a hallmark. Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): An atypical acute respiratory distress syndrome working hypothesis. Interleukin 1 blockade with high dose intravenous anakinra in patients with COVID-19, acute respiratory distress syndrome and hyper-inflammation: A retrospective cohort study. [Extracted from the article]

: Copyright of Annals of Cardiac Anaesthesia is the property of Wolters Kluwer India Pvt Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Andreottola, G., Foladori, P., Nardelli, P., Denicolo, A.

المصدر: Water Science & Technology; 2005, Vol. 51 Issue 1, p71-79, 9p

مصطلحات موضوعية: WATER quality management, WINE making -- Environmental aspects, INDUSTRIAL wastes, ACTIVATED sludge process, BIODEGRADATION, EFFLUENT quality, WASTEWATER treatment

مستخلص: The treatment of winery wastewater was performed at full-scale applying a two-stage fixed bed biofilm reactor (FBBR) system for the discharge in the sewerage. The results of the first year of operation at the full-scale plant are presented. Values of removed organic loads and effluent concentrations were interpreted on the basis of the COD fractionation of influent wastewater assessed through respirometric tests. The average removal efficiency of total COD was 91%. It was not possible to reach an higher efficiency because of the unbiodegradable soluble fraction of COD (about 10% of total COD on average during the whole year), that cannot be removed by biological process or settling. Due to the high empty space offered by the plastic carriers, FBBRs did not require backwashing during the seasonal operationing period of the plant (September-March). In comparison with other treatment systems the FBBR configuration allows one to ensure a simple management, to obtain high efficiency also in the case of higher fluctuations of flow and loads and to guarantee a good settleability of the sludge, without bulking problems. [ABSTRACT FROM AUTHOR]

: Copyright of Water Science & Technology is the property of IWA Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Andreottola, G., Damiani, E., Foladori, P., Nardelli, P., Ragazzi, M.

المصدر: Water Science & Technology; 2003, Vol. 48 Issue 11/12, p169-177, 9p

مصطلحات موضوعية: INDUSTRIAL wastes, WATER quality management, SEWAGE purification, TRICKLING filters, ENERGY consumption, SEWAGE disposal plants, BIOREACTORS, BIOMASS

مستخلص: Tourists visiting mountain refuges in the Alps have increased significantly in the last decade and the number of refuges and huts at high altitude too. In this research the results of an intensive monitoring of a wastewater treatment plant (WWTP) for a tourist mountain refuge located at 2,981 m a.s.l. are described. Two biofilm reactors were adopted: (a) a Moving Bed Biofilm Reactor (MBBR); (b) a submerged Fixed Bed Biofilm Reactor (FBBR). The aims of this research were: (i) the evaluation of the main parameters characterising the processes and involved in the design of the wastewater plants, in order to compare advantages and disadvantages of the two tested alternatives; (ii) the acquisition of an adequate knowledge of the problems connected with the wastewater treatment in alpine refuges. The main results have been: (i) a quick start-up of the biological reactors obtainable thanks to a pre-colonization before the transportation of the plastic carriers to the refuge at the beginning of the tourist season; (ii) low volume and area requirement; (iii) significantly higher removal efficiency compared to other fixed biomass systems, such as trickling filters, but the energy consumption is higher. [ABSTRACT FROM AUTHOR]

: Copyright of Water Science & Technology is the property of IWA Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)