التفاصيل البيبلوغرافية
| العنوان: |
A Convenient Synthesis of 1,4-Disubstituted Isoquinolines by Reactions of α-Substituted 2-Lithio-β-methoxystyrenes with Nitriles. |
| المؤلفون: |
Kazuhiro Kobayashi, Kazutaka Hayashi, Kazuna Miyamoto, Osamu Morikawa, Hisatoshi Konishi |
| المصدر: |
Synthesis; 2006, Vol. 2006 Issue 17, p2934-2938, 5p |
| مصطلحات موضوعية: |
ISOQUINOLINE synthesis, METHOXY compounds, STYRENE derivatives, NITRILE derivatives, BUTYLLITHIUM, SUBSTITUENTS (Chemistry) |
| مستخلص: |
It has been found that halogen-lithium exchange between α-substituted 2-bromo-β-methoxystyrene derivatives and n-butyllithium generates α-substituted 2-lithio-β-methoxystyrene derivatives, which successfully react with a range of nitriles to afford the corresponding 1,4-disubstituted isoquinolines in reasonable yields. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
