التفاصيل البيبلوغرافية
| العنوان: |
De‐identification procedures for magnetic resonance images and the impact on structural brain measures at different ages. |
| المؤلفون: |
Buimer, Elizabeth E. L., Schnack, Hugo G., Caspi, Yaron, Haren, Neeltje E. M., Milchenko, Mikhail, Pas, Pascal, Hulshoff Pol, Hilleke E., Brouwer, Rachel M. |
| المصدر: |
Human Brain Mapping; Aug2021, Vol. 42 Issue 11, p3643-3655, 13p |
| مصطلحات موضوعية: |
MAGNETIC resonance imaging, BRAIN imaging, YOUNG adults, INTRACLASS correlation |
| مستخلص: |
Surface rendering of MRI brain scans may lead to identification of the participant through facial characteristics. In this study, we evaluate three methods that overwrite voxels containing privacy‐sensitive information: Face Masking, FreeSurfer defacing, and FSL defacing. We included structural T1‐weighted MRI scans of children, young adults and older adults. For the young adults, test–retest data were included with a 1‐week interval. The effects of the de‐identification methods were quantified using different statistics to capture random variation and systematic noise in measures obtained through the FreeSurfer processing pipeline. Face Masking and FSL defacing impacted brain voxels in some scans especially in younger participants. FreeSurfer defacing left brain tissue intact in all cases. FSL defacing and FreeSurfer defacing preserved identifiable characteristics around the eyes or mouth in some scans. For all de‐identification methods regional brain measures of subcortical volume, cortical volume, cortical surface area, and cortical thickness were on average highly replicable when derived from original versus de‐identified scans with average regional correlations >.90 for children, young adults, and older adults. Small systematic biases were found that incidentally resulted in significantly different brain measures after de‐identification, depending on the studied subsample, de‐identification method, and brain metric. In young adults, test–retest intraclass correlation coefficients (ICCs) were comparable for original scans and de‐identified scans with average regional ICCs >.90 for (sub)cortical volume and cortical surface area and ICCs >.80 for cortical thickness. We conclude that apparent visual differences between de‐identification methods minimally impact reliability of brain measures, although small systematic biases can occur. [ABSTRACT FROM AUTHOR] |
|
Copyright of Human Brain Mapping is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder