التفاصيل البيبلوغرافية
| العنوان: |
Six-Month Prostate Cancer Empowerment Program (PC-PEP) Improves Urinary Function: A Randomized Trial. |
| المؤلفون: |
Lawen, Tarek, Ilie, Gabriela, Mason, Ross, Rendon, Ricardo, Spooner, Jesse, Champion, Emmi, Davis, Jessica, MacDonald, Cody, Kucharczyk, Michael J., Patil, Nikhilesh, Bowes, David, Bailly, Greg, Bell, David, Lawen, Joseph, Wilke, Derek, Kephart, George, Rutledge, Robert David Harold |
| المصدر: |
Cancers; Mar2024, Vol. 16 Issue 5, p958, 34p |
| مصطلحات موضوعية: |
PROSTATE tumors treatment, URINARY organ physiology, PATIENT compliance, PATIENT education, SELF-efficacy, STRESS management, DIGESTION, SECONDARY analysis, KEGEL exercises, HUMAN sexuality, EVALUATION of human services programs, QUESTIONNAIRES, RADICAL prostatectomy, PROSTATE tumors, AEROBIC exercises, HORMONE therapy, SOCIAL support, HEALTH outcome assessment, CANCER patient psychology, NUTRITION education, PHYSICAL activity, EVALUATION |
| مصطلحات جغرافية: |
NOVA Scotia |
| مستخلص: |
Simple Summary: In this research, we explore the effectiveness of a unique home-based 6-month comprehensive program designed to empower prostate cancer patients during their treatment. The Prostate Cancer-Patient Empowerment Program (PC-PEP) aims to enhance the quality of life for men undergoing curative treatment for prostate cancer, focusing on improving urologic function. Through a blend of physical activities, dietary education and recommendations, stress management, and social support, PC-PEP offers an innovative approach to patient care. This study rigorously assesses the impact of PC-PEP through a detailed 6-month comparison with standard care, evaluating its potential to significantly improve patient-reported outcomes. Our findings hold the promise of reshaping patient care strategies, presenting a potentially valuable addition to clinical practices for men battling prostate cancer, with the hope of improving not just their physical well-being but also their overall quality of life. Purpose: This is a secondary analysis examining a six-month home-based Prostate Cancer-Patient Empowerment Program (PC-PEP) on patient-reported urinary, bowel, sexual, and hormonal function in men with curative prostate cancer (PC) against standard of care. Methods: In a crossover clinical trial, 128 men scheduled for PC surgery (n = 62) or radiotherapy with/without hormones (n = 66) were randomized to PC-PEP (n = 66) or waitlist-control and received the standard of care for 6 months, and then PC-PEP to the end of the year. PC-PEP included daily emails with video instructions, aerobic and strength training, dietary guidance, stress management, and social support, with an initial PFMT nurse consultation. Over 6 months, participants in the PC-PEP received optional text alerts (up to three times daily) reminding them to follow the PFMT video program, encompassing relaxation, quick-twitch, and endurance exercises; compliance was assessed weekly. Participants completed baseline, 6, and 12-month International Prostate Symptom Score (IPSS) and Expanded Prostate Cancer Index Composite (EPIC) questionnaires. Results: At 6 months, men in the PC-PEP reported improved urinary bother (IPSS, p = 0.004), continence (EPIC, p < 0.001), and irritation/obstruction function (p = 0.008) compared to controls, with sustained urinary continence benefits at 12 months (p = 0.002). Surgery patients in the waitlist-control group had 3.5 (95% CI: 1.2, 10, p = 0.024) times and 2.3 (95% CI: 0.82, 6.7, p = 0.11) times higher odds of moderate to severe urinary problems compared to PC-PEP at 6 and 12 months, respectively. Conclusions: PC-PEP significantly improves lower urinary tract symptoms, affirming its suitability for clinical integration alongside established mental health benefits in men with curative prostate cancer. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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