التفاصيل البيبلوغرافية
| العنوان: |
The Epidemiology, Diagnosis, and Management of Aristolochic Acid Nephropathy. |
| المؤلفون: |
Gökmen, M. Refik, Cosyns, Jean-Pierre, Arlt, Volker M., Stiborová, Marie, Phillips, David H., Schmeiser, Heinz H., Simmonds, Monique S. J., Cook, Terence, Vanherweghem, Jean-Louis, Nortier, Joëlle L., Lord, Graham M. |
| المصدر: |
Annals of Internal Medicine; 3/19/2013, Vol. 158 Issue 6, p469-477, 9p, 1 Color Photograph, 2 Diagrams, 1 Map |
| مصطلحات موضوعية: |
KIDNEY disease treatments, CHINESE medicine, HERBAL medicine, ARISTOLOCHIC acid, TRANSITIONAL cell carcinoma, KIDNEY failure, EVIDENCE-based medicine, DISEASE risk factors |
| مستخلص: |
It has been 20 years since the first description of a rapidly progres-sive renal disease that is associated with the consumption of Chi-nese herbs containing aristolochic acid (AA) and is now termed aristolochic acid nephropathy (AAN). Recent data have shown that AA is also the primary causative agent in Balkan endemic nephrop-athy and associated urothelial cancer. Aristolochic acid nephropathy is associated with a high long-term risk for renal failure and urothe-lial cancer, and the potential worldwide population exposure is enormous. This evidence-based review of the diagnostic approach to and management of AAN draws on the authors' experience with the largest and longest-studied combined cohort of patients with this condition. It is hoped that a better understanding of the im-portance of this underrecognized and severe condition will improve epidemiologic, preventive, and therapeutic strategies to reduce the global burden of this disease. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
