دورية أكاديمية

Transporter Imbalance Implicated in Schizophrenia.

التفاصيل البيبلوغرافية
العنوان: Transporter Imbalance Implicated in Schizophrenia.
المصدر: Indian Practitioner; May2021, Vol. 74 Issue 5, p12-12, 2/3p
مصطلحات موضوعية: SCHIZOPHRENIA -- Physiological aspects, ION transport (Biology), COGNITION disorders, GABA agents, BUMETANIDE, NEUROTRANSMITTERS
مستخلص: The article discusses research which investigated the possible contribution of chloride ion transporter imbalance to the cognitive symptoms in schizophrenia, conducted by professor Marco Martina and colleagues, published in an issue of "Science Advances" journal. Topics explored include the excitatory response of the GABAA inhibitory current in the brain to the imbalance, the chloride transporters that determine GABAA polarity, and the use of bumetanide to inhibit transporter activity.
قاعدة البيانات: Complementary Index