التفاصيل البيبلوغرافية
| العنوان: |
One pair of new enantiomeric trinorsesquiterpenes from the aerial parts of Justicia gendarussa. |
| المؤلفون: |
Zhang, Hai-Xin, Xia, Zhao, Xu, Tian-Qi, Xu, Wei, Chen, Yi-Min, Zhou, Guang-Xiong |
| المصدر: |
Journal of Asian Natural Products Research; Dec2021, Vol. 23 Issue 12, p1140-1147, 8p |
| مصطلحات موضوعية: |
LIPOPOLYSACCHARIDES, BIOLOGICAL models, IN vitro studies, TERPENES, HIGH performance liquid chromatography, PLANT anatomy, ANTI-inflammatory agents, MACROPHAGES, RESEARCH funding, DESCRIPTIVE statistics, PLANT extracts, MOLECULAR structure, NITRIC oxide, DATA analysis software, CELL surface antigens, SPECTRUM analysis, MICE, IMMUNODIAGNOSIS |
| مصطلحات جغرافية: |
CHINA |
| مستخلص: |
A pair of new enantiomeric trinorsesquiterpenes, (+)-genpenterpene A (1a) and (-)-genpenterpene A (1b), together with seven known compounds (2–8), were isolated from the aerial parts of Justicia gendarussa Burm.f.. All of these known compounds were isolated from this plant for the first time. Racemic genpenterpene A was separated by chiral HPLC column. Their chemical structures were elucidated based on extensive spectroscopic analysis, single crystal X-ray diffraction, and ECD calculations. (+)-genpenterpene A (1a) exhibited potent inhibitory effect against nitric oxide production in lipopolysaccharide-activated RAW 264.7 mouse macrophage cells with an IC50 value of 9.54 ± 1.02 μM. [ABSTRACT FROM AUTHOR] |
|
Copyright of Journal of Asian Natural Products Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
