دورية أكاديمية

Diverse neolignans and lignans from an aqueous extract of the Angelica sinensis root head.

التفاصيل البيبلوغرافية
العنوان: Diverse neolignans and lignans from an aqueous extract of the Angelica sinensis root head.
المؤلفون: Xia, Zhao, Chen, You-Zhe, Xu, Cheng-Bo, Zhu, Cheng-Gen, Lei, Xiao-Qiang, Guo, Qing-Lan, Shi, Jian-Gong
المصدر: Journal of Asian Natural Products Research; Oct2023, Vol. 25 Issue 10, p919-940, 22p
مصطلحات موضوعية: BIOCHEMISTRY, EXPERIMENTAL design, LIGNANS, HERBAL medicine, HIGH performance liquid chromatography, DONG quai, PHENOMENOLOGICAL biology, WATER, NUCLEAR magnetic resonance spectroscopy, PLANT roots, EDIBLE plants, TOMOGRAPHY, CRYSTALLOGRAPHY, RESEARCH funding, MASS spectrometry, PLANT extracts, MOLECULAR structure, BIOLOGICAL assay, CHINESE medicine, SPECTRUM analysis
مستخلص: Neolignans and lignans with diverse new chemical structures, including eleven pairs of separated chiral enantiomers [(+)-/(−)-1–(+)-/(−)-5, (+)-/(−)-8, (+)-/(−)-10, and (+)-/(−)-12–(+)-/(−)-15], two achiral compounds (6 and 9), and an unseparated racemate [(±)-11], together with a new natural product (7) and 21 known derivatives, were isolated from an aqueous extract of the Angelica sinensis root head (guitou). Among the chiral isolates, (+)-/(−)-13 and (+)-/(−)-15 were scalemic pairs with enantiomeric ratios of around 3:1 and 1.5:1, respectively, while others were enantiomeric equivalent pairs. This indicates that the diverse neolignans in A. sinensis are biosynthesized via different pathways with varying degrees of stereo-controlled manners. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:10286020
DOI:10.1080/10286020.2023.2173181