المصدر: A Phase 2, Multi-Center, Randomized, Double-Blind, Controlled Trial Evaluating the Safety and Efficacy of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06422884Test

المصدر: A Phase IIa/IIb, Randomised, Double Blind, Placebo-controlled, Parallel-group Dose-finding Study to Examine the Efficacy and Safety of BI 1839100 Administered Orally Over a 12-week Treatment Period in Patients With Idiopathic Pulmonary Fibrosis or Progressive Pulmonary Fibrosis With Clinically Meaningful Cough

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06360094Test

Other URLs: https://www.mystudywindow.comTest

المصدر: A Randomised, Double-blind, Placebo-controlled, Dose-finding Study Evaluating Efficacy, Safety, and Tolerability of Different Oral Doses of BI 1819479 Over at Least 24 Weeks in Patients With Idiopathic Pulmonary Fibrosis (IPF)

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06335303Test

Other URLs: http://www.mystudywindow.comTest

المصدر: Biomarker Modulation and the Inhibition of Natural Killer Type 1 (NKT1) Cells by Oral GRI-0621 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06331624Test

المصدر: Garantzt S, Steele MP, Schwartz DA. Pulmonary fros: thkg outse of the lung. J Cl vest. 2004 Aug;114(3):319-21. do 10.1172/JC2497.
Raghu G, Chen SY, Yeh WS, MaronB, LQ, Lee YC, Collard HR. path pulmonary fros US Medare benefrs aged 65 years and older: cence, prevalence, and surval, 2001-11. Lancet Resp Med. 2014 Jul;2(7):566-72. do 10.1016/S2213-2600(14)70101-8. Epub 2014 May 27. Erratum : Lancet Resp Med. 2014 Jul;2(7):e12.
Navaratnam V, Flemg KM, West J, Smh CJ, Jenks RG, Fogarty A, Hubbard RB. The rg cence of path pulmonary fros the U.K. Thorax. 2011 Jun;66(6):462-7. do 10.1136/thx.2010.148031. Epub 2011 Apr 27.
Lederer DJ, Martez FJ. path Pulmonary Fros. N Engl J Med. 2018 Aug 23;379(8):797-798. do 10.1056/NEJMc1807508. No abstract avaable.
Phase IIa Investigation of H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06325696Test

Other URLs: https://clinicalstudies.info.nih.gov/cgi/detail.cgi?B_001577-E.htmlTest

المؤلفون: National Heart, Lung, and Blood Institute (NHLBI)

المساهمون: Imre Noth, MD, Department Chair of Pulmonary & Critical Care

المصدر: Lederer DJ, Martez FJ. path Pulmonary Fros. N Engl J Med. 2018 May 10;378(19):1811-1823. do 10.1056/NEJMra1705751. No abstract avaable.
Ley B, Ryerson CJ, Vtghoff E, Ryu JH, TomassettS, Lee JS, PolettV, BucclM, Elker BM, Jones KD, Kg TE Jr, Collard HR. A multensnal dex and stagg system for path pulmonary fros. Ann tern Med. 2012 May 15;156(10):684-91. do 10.7326/0003-4819-156-10-201205150-00004.
Podolanczuk AJ, K JS, Cooper CB, Lasky JA, Murray S, Oldham JM, Raghu G, Flaherty KR, Spo C, Noth Martez FJ; PRECNS Study Team. Desn and ratnale for the prospecte treatment effacy F usg genotype for NAC selectn (PRECNS) clal trl. BMC Pulm Med. 2022 Dec 13;22(1):475. do 10.1186/s12890-022-02281-8.
Humphrs SM, Swr JJ, Brown KK, Strand M, Gong Q, Sundy JS, Raghu G, Schwarz M Flaherty KR, Sood R, O'Rrdan TG, Lynch DA. Quantate hh-resolutn computed tomography fros score: performance characterts path pulmonary fros. Eur Resp J. 2018 Sep 17;52(3):1801384. do 10.1183/13993003.01384-2018. Prt 2018 Sep.
Humphrs SM, YagashK, Huckleberry J, Rho BH, Schroeder JD, Strand M, Schwarz M Flaherty KR, KazeroonEA, van Beek EJR, Lynch DA. path Pulmonary Fros: Data-dren Textural Analys of Extent of Fros at Basele and 15-Month Follow-up. Radlogy. 2017 Oct;285(1):270-278. do 10.1148/radl.2017161177. Epub 2017 May 10.
Kg TE Jr, Bradford WZ, Castro-BernardS, Fagan EA, Glaspole Glassberg MK, Gora E, Hopks PM, Kardatzke D, Lancaster L, Lederer DJ, Nathan SD, Perea CA, Sahn SA, Sussman R, Swr JJ, Noble PW; ASCEND Study Group. A phase 3 trl of pfenone patnts wh path pulmonary fros. N Engl J Med. 2014 May 29;370(22):2083-92. do 10.1056/NEJMoa1402582. Epub 2014 May 18. Erratum : N Engl J Med. 2014 Sep 18;371(12):1172.
RheldL, du Bo RM, Raghu G, Azuma A, Brown KK, Costabel U, Cott V, Flaherty KR, Hansell DM, oue Y, K DS, Kolb M, Nholson AG, Noble PW, Selman M, TanuchH, Brun M, Le Maulf F, Gard M, Stowasser S, Schlenker-Herceg R, Dse B, Collard HR; PULS Trl vestators. Effacy and safety of ntedan path pulmonary fros. N Engl J Med. 2014 May 29;370(22):2071-82. do 10.1056/NEJMoa1402584. Epub 2014 May 18. Erratum : N Engl J Med. 2015 Aug 20;373(8):782.
Rehmann WM, Yu YF, Macaulay D, Wu EQ, Nathan SD. Change forced val capacy and assocted subsequent outcomes patnts wh newly dgnosed path pulmonary fros. BMC Pulm Med. 2015 Dec 29;15:167. do 10.1186/s12890-015-0161-5.
Schmt SL, Tayob N, Han MK, Zappala C, Kervsky D, Murray S, Wells AU, Brown KK, Martez FJ, Flaherty KR. Predtg pulmonary fros dease course from past trends pulmonary functn. Chest. 2014 Mar 1;145(3):579-585. do 10.1378/chest.13-0844.
PaternMO, BY, Rek D, Wang Y, KarShah BA, Chowdhury BA. Acute Exacerbatn and Decle Forced Val Capacy Are Assocted wh creased Mortaly path Pulmonary Fros. Ann Am Thorac Soc. 2017 Sep;14(9):1395-1402. do 10.1513/AnnalsATS.201606-458OC.
The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06323876Test

المصدر: A Phase 2, Randomized, Double-Blind, Placebo Controlled, Parallel Group Study (TRANSFORM) to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06317285Test

المصدر: A Phase I, Single-center, Randomized, Double-blind, Single-dose, Dose-ascending, Placebo-controlled Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers.

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06267183Test

المؤلفون: Cornell University, Massachusetts General Hospital, University of Michigan, National Heart, Lung, and Blood Institute (NHLBI)

المساهمون: Hal Chapman, Professor, Medicine

المصدر: MontesSB, qurdo-Garc D, Desogere P, Abston E, Lng LL, Dumarthy S, Seethamraju R, LanutM, Caravan P, Catana C. Type Collagen-targeted Posron Emsn Tomography agg path Pulmonary Fros: Fst--Human Studs. Am J Resp Cr Care Med. 2019 Jul 15;200(2):258-261. do 10.1164/rccm.201903-0503LE. No abstract avaable.
Izquierdo-Garcia D, Desogere P, Fur ML, Shuvaev S, Zhou IY, Ramsay I, Lanuti M, Catalano OA, Catana C, Caravan P, Montesi SB. Biodistribution, Dosimetry, and Pharmacokinetics of 68Ga-CBP8: A Type I Collagen-Targeted PET Probe. J Nucl Med. 2023 May;64(5):775-781. doi: 10.2967/jnumed.122.264530. Epub 2022 Dec 8.
Collagen-targeted PET Imaging for Assessment of EGCG Effect

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06265532Test

المصدر: An Open-label, Single-group Trial to Evaluate the Effect of Pirfenidone on the Pharmacokinetics of a Single Oral Dose of BI 1015550

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06241560Test

Other URLs: https://www.mystudywindow.comTest