رسالة جامعية

Curating and analysing the genome of a model eukaryote

التفاصيل البيبلوغرافية
العنوان: Curating and analysing the genome of a model eukaryote
المؤلفون: Wood, Valerie
بيانات النشر: University of Manchester, 2019.
سنة النشر: 2019
المجموعة: University of Manchester
مصطلحات موضوعية: 579.5, Schizosaccharomyces pombe, biocuration, annotation, genome, gene ontology
الوصف: This work describes the biocuration of the fission yeast Schizosaccharomyces pombe, and how this has contributed to the development of fission yeast as a model species. I recount the curation and refinement of the gene complement, and manually curated ortholog inventories and describe how these two resources have been pivotal for comparative analysis. I outline the mechanisms of functional curation using ontologies, the PomBase community curation initiative and ongoing curation work to construct a qualitative model of cellular pathways. I describe how functional curation has been used to analyse important genome-wide datasets. Finally, the tools and resources developed to curate, display and enable interrogation and reuse of data are outlined.
نوع الوثيقة: Electronic Thesis or Dissertation
اللغة: English
الوصول الحر: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.825789Test
رقم الانضمام: edsble.825789
قاعدة البيانات: British Library EThOS