المؤلفون: Michalec, Barret, Cuddy, Monica M., Felix, Kaitlyn, Gur-Arie, Rachel, Tilburt, Jon C., Hafferty, Frederic W.

المصدر: Human Factors in Healthcare ; volume 5, page 100061 ; ISSN 2772-5014

الإتاحة: https://doi.org/10.1016/j.hfh.2023.100061Test
https://api.elsevier.com/content/article/PII:S2772501423000283?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2772501423000283?httpAccept=text/plainTest

المؤلفون: Kawam, Omar, Zhu, Xuan, Eton, David T., Martin-Lillie, Charlene, Finney Rutten, Lila J., Shapiro, Shane, Tilburt, Jon C., Master, Zubin

المساهمون: National Institutes of Health, National Institute on Aging

المصدر: Stem Cell Reports ; volume 18, issue 8, page 1549-1554 ; ISSN 2213-6711

مصطلحات موضوعية: Cell Biology, Developmental Biology, Genetics, Biochemistry

الإتاحة: https://doi.org/10.1016/j.stemcr.2023.06.004Test
https://api.elsevier.com/content/article/PII:S2213671123002333?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2213671123002333?httpAccept=text/plainTest

المؤلفون: Joyce, Daniel D., Tilburt, Jon C., Pacyna, Joel E., Cina, Kristin, Petereit, Daniel G., Koller, Kathryn R., Flanagan, Christie A., Stillwater, Barbara, Miller, Mariam, Kaur, Judith S., Peil, Elizabeth, Zahrieh, David, Dueck, Amylou C., Montori, Victor M., Frosch, Dominick L., Volk, Robert J., Kim, Simon P.

المساهمون: National Institute on Minority Health and Health Disparities, Patient-Centered Outcomes Research Institute

المصدر: Urology ; volume 175, page 90-95 ; ISSN 0090-4295

مصطلحات موضوعية: Urology

الإتاحة: https://doi.org/10.1016/j.urology.2023.02.029Test
https://api.elsevier.com/content/article/PII:S0090429523001991?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0090429523001991?httpAccept=text/plainTest

المؤلفون: Sharma, Pravesh, Patten, Christi A., Tilburt, Jon C., Cheville, Andrea L., Pritchett, Joshua C., Brewer, LaPrincess C., White, Richard O., Kelpin, Sydney S., Albertie, Monica, Brockman, Tabetha A., Doubeni, Chyke A.

المصدر: Journal of Clinical and Translational Science ; volume 6, issue 1 ; ISSN 2059-8661

مصطلحات موضوعية: General Medicine

الوصف: COVID-19 has widened the existing digital divide, especially for people from socially and economically deprived communities. We describe a program evaluation using a community participatory approach to develop self-reported items of patient experience with technology inclusive of digital access and literacy. The feedback received from Community Advisory Boards and Community Engagement Studio members led to the evaluation and refinement of the individual items. The community-based participatory approach highlighted in our paper to develop these items could serve as a model for other screening tool development for enhancing equity and inclusiveness in clinical care and research.

الإتاحة: https://doi.org/10.1017/cts.2022.451Test
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S2059866122004514Test

المؤلفون: Stout, Jeremiah, Smith, Cambray, Buckner, Jan, Adjei, Alex A., Wentworth, Mark, Tilburt, Jon C., Master, Zubin

المساهمون: Ugalde, Anna, National Center for Advancing Translational Sciences, Center of Excellence in Regulatory Science and Innovation Scholars Award to Yale and Mayo Clinic

المصدر: PLOS ONE ; volume 16, issue 12, page e0261478 ; ISSN 1932-6203

الوصف: The U.S. Food and Drug Administration (FDA) allows patients with serious illnesses to access investigational drugs for “compassionate use” outside of clinical trials through expanded access (EA) Programs. The federal Right-to-Try Act created an additional pathway for non-trial access to experimental drugs without institutional review board or FDA approval. This removal of oversight amplifies the responsibility of physicians, but little is known about the role of practicing physicians in non-trial access to investigational drugs. We undertook semi-structured interviews to capture the experiences and opinions of 21 oncologists all with previous EA experience at a major cancer center. We found five main themes. Participants with greater EA experience reported less difficulty accessing drugs through the myriad of administrative processes and drug company reluctance to provide investigational products while newcomers reported administrative hurdles. Oncologists outlined several rationales patients offered when seeking investigational drugs, including those with stronger health literacy and a good scientific rationale versus others who remained skeptical of conventional medicine. Participants reported that most patients had realistic expectations while some had unrealistic optimism. Given the diverse reasons patients sought investigational drugs, four factors—scientific rationale, risk-benefit ratio, functional status of the patient, and patient motivation—influenced oncologists’ decisions to request compassionate use drugs. Physicians struggled with a “right-to-try” framing of patient access to experimental drugs, noting instead their own responsibility to protect patients’ best interest in the uncertain and risky process of off-protocol access. This study highlights the willingness of oncologists at a major cancer center to pursue non-trial access to experimental treatments for patients while also shedding light on the factors they use when considering such treatment. Our data reveal discrepancies between ...

الإتاحة: https://doi.org/10.1371/journal.pone.0261478Test

المؤلفون: DeMartino, Erin S., Tilburt, Jon C.

المصدر: Chest ; volume 159, issue 6, page 2163-2164 ; ISSN 0012-3692

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine, Critical Care and Intensive Care Medicine, Pulmonary and Respiratory Medicine

الإتاحة: https://doi.org/10.1016/j.chest.2021.03.061Test
https://api.elsevier.com/content/article/PII:S0012369221006784?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0012369221006784?httpAccept=text/plainTest

المؤلفون: Master, Zubin, Adjei, Alex A, Hargraves, Ian G, Montori, Victor M, Tilburt, Jon C

المصدر: JNCI: Journal of the National Cancer Institute ; volume 113, issue 3, page 340-341 ; ISSN 0027-8874 1460-2105

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1093/jnci/djaa192Test
http://academic.oup.com/jnci/article-pdf/113/3/340/36419133/djaa192.pdfTest

المؤلفون: Hafferty, Frederic W., O’Brien, Bridget C., Tilburt, Jon C.

المصدر: Academic Medicine ; volume 95, issue 6, page 833-837 ; ISSN 1040-2446

الوصف: With ever-growing emphasis on high-stakes testing in medical education, such as the Medical College Admission Test and the United States Medical Licensing Examination Step 1, there has been a recent surge of concerns on the rise of a “Step 1 climate” within U.S. medical schools. The authors propose an alternative source of the “climate problem” in current institutions of medical education. Drawing on the intertwined concepts of trust and professionalism as organizational constructs, the authors propose that the core problem is not hijacking-by-exam but rather a hijackable learning environment weakened by a pernicious and under-recognized tide of commodification within the U.S. medical education system. The authors discuss several factors contributing to this weakening of medicine’s control over its learning environments, including erosion of trust in medical school curricula as adequate preparation for entry into the profession, increasing reliance on external profit-driven sources of medical education, and the emergence of an internal medical education marketplace. They call attention to breaches in the core tenets of a profession—namely a logic that differentiates its work from market and managerial forces, along with related slippages in discretionary decision making. The authors suggest reducing reliance on external performance metrics (high-stakes exams and corporate rankings), identifying and investing in alternative metrics that matter, abandoning the marketization of medical education “products,” and attending to the language of educational praxis and its potential corruption by market and managerial lexicons. These steps might salvage some self-governing independence implied in the term “profession” and make possible (if not probable) a recovery of a public trust becoming of the term and its training institutions.

الإتاحة: https://doi.org/10.1097/acm.0000000000003193Test

المؤلفون: Tilburt, Jon C.

المصدر: Mayo Clinic Proceedings ; volume 95, issue 2, page 221-223 ; ISSN 0025-6196

مصطلحات موضوعية: General Medicine

الإتاحة: https://doi.org/10.1016/j.mayocp.2019.12.026Test
https://api.elsevier.com/content/article/PII:S0025619619311243?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0025619619311243?httpAccept=text/plainTest

المؤلفون: Joyce, Daniel D, Schulte, Phillip J, Kwon, Eugene D, Dusetzina, Stacie B, Moses, Kelvin A, Sharma, Vidit, Penson, David F, Tilburt, Jon C, Boorjian, Stephen A

المصدر: J Urol ; ISSN:1527-3792 ; Volume:210 ; Issue:2

مصطلحات موضوعية: costs and cost analysis, neoplasm metastasis, prostatic neoplasms

الوصف: Assessments of financial toxicity among patients with metastatic prostate cancer are lacking. Using patient surveys, we sought to identify coping mechanisms and assess characteristics associated with lower financial toxicity.

العلاقة: https://doi.org/10.1097/JU.0000000000003506Test; https://pubmed.ncbi.nlm.nih.gov/37416955Test

الإتاحة: https://doi.org/10.1097/JU.0000000000003506Test
https://pubmed.ncbi.nlm.nih.gov/37416955Test