نتائج البحث

1

دورية أكاديمية

The biotherapeutic Clostridium butyricum MIYAIRI 588 strain potentiates enterotropism of Rorγt + Treg and PD-1 blockade efficacy

المؤلفون: Paz del Socorro, Thomas, Oka, Kentaro, Boulard, Olivier, Takahashi, Motomichi, Poulin, Lionel, Franz, Hayashi, Atsushi, Chamaillard, Mathias

المساهمون: Laboratoire de Physiologie Cellulaire : Canaux ioniques, inflammation et cancer - U 1003 (PHYCELL), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Miyarisan Pharmaceutical Co. (Miyarisan Pharmaceutical Co.), Miyarisan Pharmaceutical Co.

المصدر: ISSN: 1949-0976.

مصطلحات موضوعية: Immune checkpoint inhibitors interferon gamma interleukin-10 oncomicrobiotic Rorγt + T reg, Immune checkpoint inhibitors, interferon gamma, interleukin-10, oncomicrobiotic, Rorγt + T reg, [SDV]Life Sciences [q-bio]

العلاقة: hal-04543189; https://hal.science/hal-04543189Test; https://hal.science/hal-04543189/documentTest; https://hal.science/hal-04543189/file/The%20biotherapeutic%20Clostridium%20butyricum%20MIYAIRI%20588%20strain%20potentiates%20enterotropism%20of%20Ror%20t%20Treg%20and%20PD-1%20blockade%20efficacy.pdfTest

الإتاحة: https://doi.org/10.1080/19490976.2024.2315631Test
https://hal.science/hal-04543189Test
https://hal.science/hal-04543189/documentTest
https://hal.science/hal-04543189/file/The%20biotherapeutic%20Clostridium%20butyricum%20MIYAIRI%20588%20strain%20potentiates%20enterotropism%20of%20Ror%20t%20Treg%20and%20PD-1%20blockade%20efficacy.pdfTest

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2

دورية أكاديمية

Therapeutic effects and mechanism of action of lavender essential oil on atopic dermatitis by modulating the STAT3/RORγt pathway

المؤلفون: Jiawei Duan, Jinkai Li, Yujiao Wang, Peijie Zhou, Xuan Wang, Ning Xia, Jie Wang, Jia Li, Wenfei Wang, Xiao Wang, Jing Sun, Dongyan Guo, Junbo Zou, Xiaofei Zhang, Changli Wang

المصدر: Arabian Journal of Chemistry, Vol 17, Iss 2, Pp 105525- (2024)

مصطلحات موضوعية: Atopic dermatitis, Lavender essential oil, STAT3, RORγt, Chemistry, QD1-999

العلاقة: http://www.sciencedirect.com/science/article/pii/S1878535223009875Test; https://doaj.org/toc/1878-5352Test; https://doaj.org/article/74435546079f45b9a6ba87bfeae8fc29Test

الإتاحة: https://doi.org/10.1016/j.arabjc.2023.105525Test
https://doaj.org/article/74435546079f45b9a6ba87bfeae8fc29Test

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النص الكامل

3

دورية أكاديمية

Discovery of Biaryl Amide Derivatives as Potent, Selective, and Orally Bioavailable RORγt Agonists for Cancer Immunotherapy

المؤلفون: Lixue Lu, Yafei Huang, Meiqi Song, Nannan Sun, Li Xia, Mingcheng Yu, Meiling Zhao, Ruomeng Qiu, Ji-an Chen, Yunpeng Zhao, Haojie Wang, Huimin Guo, Yan Li, Di Zhu, Yonghui Wang, Qiong Xie

العلاقة: https://figshare.com/articles/journal_contribution/Discovery_of_Biaryl_Amide_Derivatives_as_Potent_Selective_and_Orally_Bioavailable_ROR_t_Agonists_for_Cancer_Immunotherapy/24591888Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01492.s001Test
https://figshare.com/articles/journal_contribution/Discovery_of_Biaryl_Amide_Derivatives_as_Potent_Selective_and_Orally_Bioavailable_ROR_t_Agonists_for_Cancer_Immunotherapy/24591888Test

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4

دورية أكاديمية

IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis

المؤلفون: Valle Noguera, Ana, Sancho Temiño, Lucía, Castillo González, Raquel, Villa Gómez, Cristina, Gomez Sánchez, María José, Ochoa Ramos, Anne, González Granado, José María, Cruz Adalia, Aranzazu

مصطلحات موضوعية: 612.017, CP: Immunology, Citrobacter rodentium, HIF-1α, IL-18, IL-22, TLR2, colitis, group 3 innate lymphoid cells, infection, innate RORγt(+) cells, Inmunología, 2412.99 Otras

وصف الملف: application/pdf

العلاقة: info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-093647-B-I00/ES/CONTROL DE LA REGULACION METABOLICA Y MOLECULAR MEDIADA POR HIF-1A EN LAS CELULAS INNATAS LINFOIDES/; PID2021-122780OB-I00; CNS2022-135365; info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI20%2F00306/ES/INMUNOLOGIA, INMUNOPATOLOGIA Y TERAPIA EN ENFERMEDAD INFLAMATORIA INTESTINAL/; https://hdl.handle.net/20.500.14352/92186Test; Valle-Noguera A, Sancho-Temiño L, Castillo-González R, Villa-Gómez C, Gomez-Sánchez MJ, Ochoa-Ramos A, Yagüe-Fernández P, Soler Palacios B, Zorita V, Raposo-Ponce B, González-Granado JM, Aragonés J, Cruz-Adalia A. IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis. Cell Rep. 2023 Dec 26;42(12):113508. doi:10.1016/j.celrep.2023.113508. Epub 2023 Nov 28. PMID: 38019650.; https://www.sciencedirect.com/journal/cell-reportsTest

الإتاحة: https://doi.org/20.500.14352/92186Test
https://doi.org/10.1016/j.celrep.2023.113508Test
https://hdl.handle.net/20.500.14352/92186Test
https://www.sciencedirect.com/journal/cell-reportsTest

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النص الكامل

5

دورية أكاديمية

Virtual Screening Strategy to Identify Retinoic Acid-Related Orphan Receptor γt Modulators

المؤلفون: Elmeri M. Jokinen, Miika Niemeläinen, Sami T. Kurkinen, Jukka V. Lehtonen, Sakari Lätti, Pekka A. Postila, Olli T. Pentikäinen, Sanna P. Niinivehmas

المصدر: Molecules; Volume 28; Issue 8; Pages: 3420

مصطلحات موضوعية: molecular docking, docking rescoring, negative image-based rescoring (R-NiB), brute force negative image-based optimization (BR-NiB), pharmacophore (PHA) filtering, retinoic acid receptor-related orphan receptor gamma t (RORγt), virtual screening (VS), inflammation

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules28083420Test

الإتاحة: https://doi.org/10.3390/molecules28083420Test

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6

دورية أكاديمية

Cornus mas L. Extract Targets the Specific Molecules of the Th17/Treg Developmental Pathway in TNBS-Induced Experimental Colitis in Rats

المؤلفون: Marta Szandruk-Bender, Beata Nowak, Anna Merwid-Ląd, Alicja Z. Kucharska, Małgorzata Krzystek-Korpacka, Iwona Bednarz-Misa, Benita Wiatrak, Adam Szeląg, Narcyz Piórecki, Tomasz Sozański

المصدر: Molecules; Volume 28; Issue 7; Pages: 3034

مصطلحات موضوعية: experimental colitis, TNBS, Th17/Treg axis, IL-6, RORγt, STAT3, Foxp3, PIAS3, cornelian cherry, polyphenols

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Natural Products Chemistry; https://dx.doi.org/10.3390/molecules28073034Test

الإتاحة: https://doi.org/10.3390/molecules28073034Test

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7

دورية أكاديمية

Bile acid dysmetabolism in inflammatory bowel diseases ; Нарушение метаболизма желчных кислот при воспалительных заболеваниях кишечника

المؤلفون: Kuznetsova D.A., Lapin S.V., Gubonina I.V.

المساهمون: 1

المصدر: Almanac of Clinical Medicine; Vol 51, No 1 (2023); 1-13 ; Альманах клинической медицины; Vol 51, No 1 (2023); 1-13 ; 2587-9294 ; 2072-0505

مصطلحات موضوعية: bile acids, bile acid metabolism, bile acid malabsorption, gut microbiota, FXR, GPBAR1, PXR, RORγt, VDR, inflammatory bowel diseases, желчные кислоты, метаболизм желчных кислот, мальабсорбция желчных кислот, микробиота кишечника, воспалительные заболевания кишечника